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Diagnosis & management of alpha-gal syndrome: lessons from 2,500 patients.
Commins SP. Commins SP. Expert Rev Clin Immunol. 2020 Jul;16(7):667-677. doi: 10.1080/1744666X.2020.1782745. Epub 2020 Jul 8. Expert Rev Clin Immunol. 2020. PMID: 32571129 Free PMC article. Review.
INTRODUCTION: Alpha-gal Syndrome (AGS) is a unique allergy to non-primate mammalian meat (and derived-products) that is associated with tick bites and is due to a specific IgE antibody to the oligosaccharide galactose-alpha-1,3-galactose (alpha- …
INTRODUCTION: Alpha-gal Syndrome (AGS) is a unique allergy to non-primate mammalian meat (and derived-pro …
The Meat of the Matter: Understanding and Managing Alpha-Gal Syndrome.
Macdougall JD, Thomas KO, Iweala OI. Macdougall JD, et al. Immunotargets Ther. 2022 Sep 15;11:37-54. doi: 10.2147/ITT.S276872. eCollection 2022. Immunotargets Ther. 2022. PMID: 36134173 Free PMC article. Review.
Alpha-gal syndrome is an unconventional food allergy, characterized by IgE-mediated hypersensitivity responses to the glycan galactose-alpha-1,3-galactose (alpha-gal) and not to a food-protein. In this review, we discuss how alpha-gal
Alpha-gal syndrome is an unconventional food allergy, characterized by IgE-mediated hypersensitivity resp
Diagnosis and Management of Patients with the alpha-Gal Syndrome.
Platts-Mills TAE, Li RC, Keshavarz B, Smith AR, Wilson JM. Platts-Mills TAE, et al. J Allergy Clin Immunol Pract. 2020 Jan;8(1):15-23.e1. doi: 10.1016/j.jaip.2019.09.017. Epub 2019 Sep 28. J Allergy Clin Immunol Pract. 2020. PMID: 31568928 Free PMC article. Review.
The galactose-alpha-1,3-galactose (alpha-Gal) syndrome has many novel features that are relevant to diagnosis and management. In most cases, the diagnosis can be made on a history of delayed allergic reactions to mammalian meat and the blood test for I …
The galactose-alpha-1,3-galactose (alpha-Gal) syndrome has many novel features that are relevant to diagnosis and manag …
Tick bites, IgE to galactose-alpha-1,3-galactose and urticarial or anaphylactic reactions to mammalian meat: The alpha-gal syndrome.
Wilson JM, Erickson L, Levin M, Ailsworth SM, Commins SP, Platts-Mills TAE. Wilson JM, et al. Allergy. 2024 Jun;79(6):1440-1454. doi: 10.1111/all.16003. Epub 2024 Jan 9. Allergy. 2024. PMID: 38193233 Free PMC article. Review.
The recent recognition of a syndrome of tick-acquired mammalian meat allergy has transformed the previously held view that mammalian meat is an uncommon allergen. ...Thus, fittingly, this allergic disorder is now called the alpha-gal syndrome
The recent recognition of a syndrome of tick-acquired mammalian meat allergy has transformed the previously held view that mam …
Alpha-gal syndrome: Recognizing and managing a tick-bite-related meat allergy.
Naseem Z, Muhammad A, Chatterjee A, Rubio-Tapia A. Naseem Z, et al. Cleve Clin J Med. 2025 May 1;92(5):311-319. doi: 10.3949/ccjm.92a.24072. Cleve Clin J Med. 2025. PMID: 40312115 Free article. Review.
Alpha-gal syndrome is an emerging condition characterized by an immunoglobulin (Ig) E-mediated reaction to galactose-alpha-1,3-galactose (alpha-gal) after consumption of mammalian-derived food products. ...Symptoms range from pruritus and hives to severe syst
Alpha-gal syndrome is an emerging condition characterized by an immunoglobulin (Ig) E-mediated reaction to galactose-al
Beneficial Bloodsucking.
Crutchfield P, Hereth B. Crutchfield P, et al. Bioethics. 2025 Oct;39(8):772-781. doi: 10.1111/bioe.70015. Epub 2025 Jul 22. Bioethics. 2025. PMID: 40693342
The bite of the lone star tick spreads alpha-gal syndrome (AGS), a condition whose only effect is the creation of a severe but nonfatal red meat allergy. Public health departments warn against lone star ticks and AGS, and scientists are w …
The bite of the lone star tick spreads alpha-gal syndrome (AGS), a condition whose only effect is the creation of a sev …
Mammalian meat allergy and beyond: overview of alpha-gal syndrome.
Browning RL, Iweala OI, Jerath MR. Browning RL, et al. Curr Opin Allergy Clin Immunol. 2026 Feb 1;26(1):37-44. doi: 10.1097/ACI.0000000000001126. Epub 2025 Nov 28. Curr Opin Allergy Clin Immunol. 2026. PMID: 41330545 Review.
PURPOSE OF REVIEW: Alpha-gal syndrome (AGS) is a unique allergy to the carbohydrate galactose-alpha-1,3-galactose, which is found in mammalian products, excluding humans and Old World primates. ...
PURPOSE OF REVIEW: Alpha-gal syndrome (AGS) is a unique allergy to the carbohydrate galactose-alpha-1,3-galactos …
alpha-Gal Syndrome: Busting Paradigms in Food Allergy.
Iweala OI. Iweala OI. Ann Intern Med Clin Cases. 2023 Jun;2(6):e230578. doi: 10.7326/aimcc.2023.0578. Epub 2023 Jun 20. Ann Intern Med Clin Cases. 2023. PMID: 39555229 Free PMC article.
alpha-Gal syndrome, also known as red or mammalian meat allergy, results from immunoglobulin E-mediated hypersensitivity responses to the carbohydrate galactose-alpha-1,3-galactose (alpha-gal). Patients with alpha-gal syn
alpha-Gal syndrome, also known as red or mammalian meat allergy, results from immunoglobulin E-mediated
The Immunology of Alpha-Gal Syndrome: History, Tick Bites, IgE, and Delayed Anaphylaxis to Mammalian Meat.
Platts-Mills TAE, Gangwar RS, Workman L, Wilson JM. Platts-Mills TAE, et al. Immunol Rev. 2025 Jul;332(1):e70035. doi: 10.1111/imr.70035. Immunol Rev. 2025. PMID: 40515672 Free PMC article. Review.
The primary features of the alpha-gal syndrome (AGS) are (i) The IgE ab that are causally related to anaphylaxis with infusions of Cetuximab are specific for galactose alpha-1,3-galactose. ...The current hypothesis about the cause of the delayed reactions is …
The primary features of the alpha-gal syndrome (AGS) are (i) The IgE ab that are causally related to anaphylaxis with i …
What Does a Red Meat Allergy Have to Do With Anesthesia? Perioperative Management of Alpha-Gal Syndrome.
Dunkman WJ, Rycek W, Manning MW. Dunkman WJ, et al. Anesth Analg. 2019 Nov;129(5):1242-1248. doi: 10.1213/ANE.0000000000003460. Anesth Analg. 2019. PMID: 29847378 Review.
Over the past decade, there has been a growing awareness of a new allergic syndrome known as alpha-gal allergy or alpha-gal syndrome, commonly recognized as a red meat allergy. We performed a review of the literature to identify ar …
Over the past decade, there has been a growing awareness of a new allergic syndrome known as alpha-gal allergy or alpha-gal
354 results