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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1969 1
1971 1
1976 1
1977 1
1980 1
1981 2
1982 1
1983 1
1991 1
1993 3
1995 3
1996 1
1997 2
1998 3
1999 11
2000 5
2001 4
2002 15
2003 7
2004 13
2005 10
2006 8
2007 15
2008 16
2009 19
2010 15
2011 22
2012 24
2013 34
2014 23
2015 19
2016 20
2017 20
2018 26
2019 28
2020 24
2021 20
2022 19
2023 20
2024 17
2025 20
2026 7

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438 results

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Filters applied: Clinical Trial, Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Effects of Oral Alpha-Lipoic Acid Treatment on Diabetic Polyneuropathy: A Meta-Analysis and Systematic Review.
Hsieh RY, Huang IC, Chen C, Sung JY. Hsieh RY, et al. Nutrients. 2023 Aug 18;15(16):3634. doi: 10.3390/nu15163634. Nutrients. 2023. PMID: 37630823 Free PMC article.
Alpha-lipoic acid (ALA) was found to improve the symptoms in patients with diabetic sensorimotor peripheral neuropathy (DSPN) by reducing oxidative stress and ameliorating microcirculation. ...
Alpha-lipoic acid (ALA) was found to improve the symptoms in patients with diabetic sensorimotor peripheral neuropathy …
Alpha Lipoic Acid Supplementation and Iron Homeostasis: A Comprehensive Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials.
Sharifi-Zahabi E, Abdollahzad H. Sharifi-Zahabi E, et al. Int J Vitam Nutr Res. 2024 Dec 27;95(1):36623. doi: 10.31083/IJVNR36623. Int J Vitam Nutr Res. 2024. PMID: 40134249 Free article.
BACKGROUND: A growing body of evidence indicates the regulating effects of alpha-lipoic acid on iron metabolism. However, findings from clinical trials are equivocal. This systematic review and meta-analysis aimed to evaluate the quantitative effect of alp …
BACKGROUND: A growing body of evidence indicates the regulating effects of alpha-lipoic acid on iron metabolism. Howeve …
Oral Alpha Lipoic Acid Treatment for Symptomatic Diabetic Peripheral Neuropathy: A Randomized Double-Blinded Placebo-Controlled Study.
El-Nahas MR, Elkannishy G, Abdelhafez H, Elkhamisy ET, El-Sehrawy AA. El-Nahas MR, et al. Endocr Metab Immune Disord Drug Targets. 2020;20(9):1531-1534. doi: 10.2174/1871530320666200506081407. Endocr Metab Immune Disord Drug Targets. 2020. PMID: 32370731 Clinical Trial.
BACKGROUND: Alpha-lipoic acid (ALA) was used in the treatment of diabetic peripheral neuropathy (DPN) using different routes, doses and treatment durations. ...
BACKGROUND: Alpha-lipoic acid (ALA) was used in the treatment of diabetic peripheral neuropathy (DPN) using different r …
Ranking Alpha Lipoic Acid and Gamma Linolenic Acid in Terms of Efficacy and Safety in the Management of Adults With Diabetic Peripheral Neuropathy: A Systematic Review and Network Meta-analysis.
Prado MB Jr, Adiao KJB. Prado MB Jr, et al. Can J Diabetes. 2024 Jun;48(4):233-243.e10. doi: 10.1016/j.jcjd.2024.01.007. Epub 2024 Jan 29. Can J Diabetes. 2024. PMID: 38295879
The purpose of this work was to summarize the available evidence about the efficacy and safety of alpha lipoic acid (ALA) and gamma linolenic acid (GLA) in the management of DN. METHODS: Using the search terms [(alpha lipoic acid o …
The purpose of this work was to summarize the available evidence about the efficacy and safety of alpha lipoic acid (AL …
Alpha-lipoic acid supplementation affects serum lipids in a dose and duration-dependent manner in different health status.
Mahmoudinezhad M, Farhangi MA. Mahmoudinezhad M, et al. Int J Vitam Nutr Res. 2023 Aug;93(4):352-361. doi: 10.1024/0300-9831/a000732. Epub 2021 Oct 4. Int J Vitam Nutr Res. 2023. PMID: 34605276 Free article.
Background: Many studies have investigated the effect of alpha-lipoic acid (ALA) supplementation on lipid profile, and different results have been obtained from these studies. ...
Background: Many studies have investigated the effect of alpha-lipoic acid (ALA) supplementation on lipid profile, and …
Alpha-lipoic acid on intermediate disease markers in overweight or obese adults: a systematic review and meta-analysis.
Luo Y, Zhang J, Guo H. Luo Y, et al. BMJ Open. 2025 Apr 3;15(4):e088363. doi: 10.1136/bmjopen-2024-088363. BMJ Open. 2025. PMID: 40180416 Free PMC article.
OBJECTIVES: To evaluate the associations between alpha-lipoic acid (ALA) intake and intermediate disease markers in overweight or obese adults. ...
OBJECTIVES: To evaluate the associations between alpha-lipoic acid (ALA) intake and intermediate disease markers in ove …
Alpha-lipoic acid (ALA) supplementation effect on glycemic and inflammatory biomarkers: A Systematic Review and meta- analysis.
Rahimlou M, Asadi M, Banaei Jahromi N, Mansoori A. Rahimlou M, et al. Clin Nutr ESPEN. 2019 Aug;32:16-28. doi: 10.1016/j.clnesp.2019.03.015. Epub 2019 May 2. Clin Nutr ESPEN. 2019. PMID: 31221283
BACKGROUND & AIMS: Several randomized clinical trials (RCTs) have investigated the effect of Alpha - Lipoic Acid (ALA) supplementation on metabolic parameters, with conflicting results. ...The results demonstrated the significant effect of ALA on Fasting …
BACKGROUND & AIMS: Several randomized clinical trials (RCTs) have investigated the effect of Alpha - Lipoic Acid (A …
Alpha-lipoic acid effect on leptin and adiponectin concentrations: a systematic review and meta-analysis of randomized controlled trials.
Haghighatdoost F, Gholami A, Hariri M. Haghighatdoost F, et al. Eur J Clin Pharmacol. 2020 May;76(5):649-657. doi: 10.1007/s00228-020-02844-w. Epub 2020 Feb 10. Eur J Clin Pharmacol. 2020. PMID: 32040596
Our aim in this meta-analysis was to determine the effect of alpha-lipoic acid (ALA) supplementation on serum levels of leptin and adiponectin. METHODS: We searched Scopus, PubMed, Google Scholar, and ISI Web of Science from inception up to July 2019. ...
Our aim in this meta-analysis was to determine the effect of alpha-lipoic acid (ALA) supplementation on serum levels of …
Does alpha-lipoic acid affect lipid profile? A meta-analysis and systematic review on randomized controlled trials.
Haghighatdoost F, Hariri M. Haghighatdoost F, et al. Eur J Pharmacol. 2019 Mar 15;847:1-10. doi: 10.1016/j.ejphar.2019.01.001. Epub 2019 Jan 8. Eur J Pharmacol. 2019. PMID: 30633888
Randomized controlled trials (RCTs) have demonstrated that alpha lipoic acid (ALA) may change lipid profile, but their results are contradictory. ...Serum total cholesterol (TC) and low density lipoprotein-cholesterol (LDL-) levels were significantly lower in …
Randomized controlled trials (RCTs) have demonstrated that alpha lipoic acid (ALA) may change lipid profile, but their …
438 results