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Diagnosis and Management of Patients with the alpha-Gal Syndrome.
Platts-Mills TAE, Li RC, Keshavarz B, Smith AR, Wilson JM. Platts-Mills TAE, et al. J Allergy Clin Immunol Pract. 2020 Jan;8(1):15-23.e1. doi: 10.1016/j.jaip.2019.09.017. Epub 2019 Sep 28. J Allergy Clin Immunol Pract. 2020. PMID: 31568928 Free PMC article. Review.
The galactose-alpha-1,3-galactose (alpha-Gal) syndrome has many novel features that are relevant to diagnosis and management. ...In general, the diagnosis also dictates the primary treatment, that is, avoiding mammalian meat and also dairy in some cases. In t …
The galactose-alpha-1,3-galactose (alpha-Gal) syndrome has many novel features that are relevant to diagnosis and manag …
Beneficial Bloodsucking.
Crutchfield P, Hereth B. Crutchfield P, et al. Bioethics. 2025 Oct;39(8):772-781. doi: 10.1111/bioe.70015. Epub 2025 Jul 22. Bioethics. 2025. PMID: 40693342
The bite of the lone star tick spreads alpha-gal syndrome (AGS), a condition whose only effect is the creation of a severe but nonfatal red meat allergy. Public health departments warn against lone star …
The bite of the lone star tick spreads alpha-gal syndrome (AGS), a condition whose only effect is …
The Immunology of Alpha-Gal Syndrome: History, Tick Bites, IgE, and Delayed Anaphylaxis to Mammalian Meat.
Platts-Mills TAE, Gangwar RS, Workman L, Wilson JM. Platts-Mills TAE, et al. Immunol Rev. 2025 Jul;332(1):e70035. doi: 10.1111/imr.70035. Immunol Rev. 2025. PMID: 40515672 Free PMC article. Review.
The primary features of the alpha-gal syndrome (AGS) are (i) The IgE ab that are causally related to anaphylaxis with infusions of Cetuximab are specific for galactose alpha-1,3-galactose. (ii) In the USA, this IgE ab is induced by bites of the tick …
The primary features of the alpha-gal syndrome (AGS) are (i) The IgE ab that are causally related to anaphylaxis with i …
Identification of Alpha-Gal glycolipids in saliva of Lone-Star Tick (Amblyomma americanum).
Sharma SR, Hussain S, Choudhary SK, Commins SP, Karim S. Sharma SR, et al. Ticks Tick Borne Dis. 2024 Nov;15(6):102384. doi: 10.1016/j.ttbdis.2024.102384. Epub 2024 Jul 24. Ticks Tick Borne Dis. 2024. PMID: 39053323 Free article.
Alpha-Gal Syndrome (AGS) is a delayed allergic reaction triggered by IgE antibodies targeting galactose-alpha-1,3-galactose (alpha-gal), prevalent in red meat. Its global significance has increased, with over 450,000 estimated cases in the United States alone …
Alpha-Gal Syndrome (AGS) is a delayed allergic reaction triggered by IgE antibodies targeting galactose-alpha-1,3-galac …
Tick bite-induced alpha-gal syndrome and immunologic responses in an alpha-gal deficient murine model.
Sharma SR, Choudhary SK, Vorobiov J, Commins SP, Karim S. Sharma SR, et al. Front Immunol. 2024 Feb 8;14:1336883. doi: 10.3389/fimmu.2023.1336883. eCollection 2023. Front Immunol. 2024. PMID: 38390396 Free PMC article.
METHODS: Lone-star tick (Amblyomma americanum) and gulf-coast tick (Amblyomma maculatum) nymphs were used to sensitize AGKO mice, followed by pork meat challenge. ...RESULTS: Our results showed a significant increase in the total IgE, IgG …
METHODS: Lone-star tick (Amblyomma americanum) and gulf-coast tick (Amblyomma maculatum) nymphs we …
Galactose-alpha-1,3-galactose syndrome.
Nguyen M, Heath J. Nguyen M, et al. J Food Allergy. 2020 Sep 1;2(1):108-110. doi: 10.2500/jfa.2020.2.200006. eCollection 2020 Sep. J Food Allergy. 2020. PMID: 39022145 Free PMC article.
The galactose-alpha-1,3-galactose (alpha-Gal) syndrome is a newly recognized and unique form of food allergy, characterized by delayed reactions to mammalian meats. ...Sensitization occurs after exposure to multiple arthropod bites, most commonly the lone …
The galactose-alpha-1,3-galactose (alpha-Gal) syndrome is a newly recognized and unique form of food allergy, character …
Alpha-gal syndrome: Recognizing and managing a tick-bite-related meat allergy.
Naseem Z, Muhammad A, Chatterjee A, Rubio-Tapia A. Naseem Z, et al. Cleve Clin J Med. 2025 May 1;92(5):311-319. doi: 10.3949/ccjm.92a.24072. Cleve Clin J Med. 2025. PMID: 40312115 Free article. Review.
Alpha-gal syndrome is an emerging condition characterized by an immunoglobulin (Ig) E-mediated reaction to galactose-alpha-1,3-galactose (alpha-gal) after consumption of mammalian-derived food products. Identified in the early 2000s, the syndrome is linked to …
Alpha-gal syndrome is an emerging condition characterized by an immunoglobulin (Ig) E-mediated reaction to galactose-al …
Association between lone star tick bites and increased alpha-gal sensitization: evidence from a prospective cohort of outdoor workers.
Mitchell CL, Lin FC, Vaughn M, Apperson CS, Meshnick SR, Commins SP. Mitchell CL, et al. Parasit Vectors. 2020 Sep 14;13(1):470. doi: 10.1186/s13071-020-04343-4. Parasit Vectors. 2020. PMID: 32928302 Free PMC article.
However, evidence prospectively linking exposure to a single tick species and an immune response to alpha-gal is lacking. METHODS: We used serum samples from a prior study cohort of outdoor workers in North Carolina, USA, with high exposure to the lone star …
However, evidence prospectively linking exposure to a single tick species and an immune response to alpha-gal is lacking. METHODS: We …
Tick Saliva and the Alpha-Gal Syndrome: Finding a Needle in a Haystack.
Sharma SR, Karim S. Sharma SR, et al. Front Cell Infect Microbiol. 2021 Jul 20;11:680264. doi: 10.3389/fcimb.2021.680264. eCollection 2021. Front Cell Infect Microbiol. 2021. PMID: 34354960 Free PMC article. Review.
Alpha-gal syndrome (AGS), a newly reported food allergy, is believed to be induced by saliva proteins decorated with a sugar molecule, the oligosaccharide galactose- -1,3-galactose (alpha-gal). ...The alpha-gal antigen was discovered in the salivary glands an …
Alpha-gal syndrome (AGS), a newly reported food allergy, is believed to be induced by saliva proteins decorated with a …
Tick exposures and alpha-gal syndrome: A systematic review of the evidence.
Young I, Prematunge C, Pussegoda K, Corrin T, Waddell L. Young I, et al. Ticks Tick Borne Dis. 2021 May;12(3):101674. doi: 10.1016/j.ttbdis.2021.101674. Epub 2021 Jan 27. Ticks Tick Borne Dis. 2021. PMID: 33529984 Free article.
Alpha-gal syndrome (AGS) refers to a delayed allergic reaction to galactose-alpha-1,3-galactose (alpha-Gal) that occurs following the consumption of mammalian meat or exposure to other animal-based foods and products. ...The proportion of AGS cases that recal …
Alpha-gal syndrome (AGS) refers to a delayed allergic reaction to galactose-alpha-1,3-galactose (alpha-Gal) that occurs …
87 results