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Diagnosis & management of alpha-gal syndrome: lessons from 2,500 patients.
Commins SP. Commins SP. Expert Rev Clin Immunol. 2020 Jul;16(7):667-677. doi: 10.1080/1744666X.2020.1782745. Epub 2020 Jul 8. Expert Rev Clin Immunol. 2020. PMID: 32571129 Free PMC article. Review.
INTRODUCTION: Alpha-gal Syndrome (AGS) is a unique allergy to non-primate mammalian meat (and derived-products) that is associated with tick bites and is due to a specific IgE antibody to the oligosaccharide galactose-alpha-1,3-galactose …
INTRODUCTION: Alpha-gal Syndrome (AGS) is a unique allergy to non-primate mammalian meat (and derived-products) …
Beneficial Bloodsucking.
Crutchfield P, Hereth B. Crutchfield P, et al. Bioethics. 2025 Oct;39(8):772-781. doi: 10.1111/bioe.70015. Epub 2025 Jul 22. Bioethics. 2025. PMID: 40693342
The bite of the lone star tick spreads alpha-gal syndrome (AGS), a condition whose only effect is the creation of a severe but nonfatal red meat allergy. Public health departments warn against lone star ticks and AGS, and sc …
The bite of the lone star tick spreads alpha-gal syndrome (AGS), a condition whose only effect is the cre …
Tick bites, IgE to galactose-alpha-1,3-galactose and urticarial or anaphylactic reactions to mammalian meat: The alpha-gal syndrome.
Wilson JM, Erickson L, Levin M, Ailsworth SM, Commins SP, Platts-Mills TAE. Wilson JM, et al. Allergy. 2024 Jun;79(6):1440-1454. doi: 10.1111/all.16003. Epub 2024 Jan 9. Allergy. 2024. PMID: 38193233 Free PMC article. Review.
Thus, fittingly, this allergic disorder is now called the alpha-gal syndrome (AGS). The syndrome is strikingly regional, reflecting the important role of tick bites in sensitization, and is more common in demographic groups at risk of tick …
Thus, fittingly, this allergic disorder is now called the alpha-gal syndrome (AGS). The syndrome is strikingly regional …
The Meat of the Matter: Understanding and Managing Alpha-Gal Syndrome.
Macdougall JD, Thomas KO, Iweala OI. Macdougall JD, et al. Immunotargets Ther. 2022 Sep 15;11:37-54. doi: 10.2147/ITT.S276872. eCollection 2022. Immunotargets Ther. 2022. PMID: 36134173 Free PMC article. Review.
In this review, we discuss how alpha-gal syndrome reframes our current conception of the mechanisms of pathogenesis of food allergy. The development of alpha-gal IgE is associated with tick bites though the possibility of other parasites promoti …
In this review, we discuss how alpha-gal syndrome reframes our current conception of the mechanisms of pathogenesis of …
Diagnosis and Management of Patients with the alpha-Gal Syndrome.
Platts-Mills TAE, Li RC, Keshavarz B, Smith AR, Wilson JM. Platts-Mills TAE, et al. J Allergy Clin Immunol Pract. 2020 Jan;8(1):15-23.e1. doi: 10.1016/j.jaip.2019.09.017. Epub 2019 Sep 28. J Allergy Clin Immunol Pract. 2020. PMID: 31568928 Free PMC article. Review.
The galactose-alpha-1,3-galactose (alpha-Gal) syndrome has many novel features that are relevant to diagnosis and management. ...Blood levels of IgE to alpha-Gal often drop in patients who avoid recurrent tick bites, but the rate of decline is v …
The galactose-alpha-1,3-galactose (alpha-Gal) syndrome has many novel features that are relevant to diagnosis and manag …
Alpha-gal syndrome: Recognizing and managing a tick-bite-related meat allergy.
Naseem Z, Muhammad A, Chatterjee A, Rubio-Tapia A. Naseem Z, et al. Cleve Clin J Med. 2025 May 1;92(5):311-319. doi: 10.3949/ccjm.92a.24072. Cleve Clin J Med. 2025. PMID: 40312115 Free article. Review.
Identified in the early 2000s, the syndrome is linked to sensitization through tick bites; in the United States, the lone star tick (Amblyomma americanum) is the main vector. ...Management focuses on avoiding foods and products that contain alpha-gal and prev …
Identified in the early 2000s, the syndrome is linked to sensitization through tick bites; in the United States, the lone star …
The Immunology of Alpha-Gal Syndrome: History, Tick Bites, IgE, and Delayed Anaphylaxis to Mammalian Meat.
Platts-Mills TAE, Gangwar RS, Workman L, Wilson JM. Platts-Mills TAE, et al. Immunol Rev. 2025 Jul;332(1):e70035. doi: 10.1111/imr.70035. Immunol Rev. 2025. PMID: 40515672 Free PMC article. Review.
The primary features of the alpha-gal syndrome (AGS) are (i) The IgE ab that are causally related to anaphylaxis with infusions of Cetuximab are specific for galactose alpha-1,3-galactose. ...With repeated tick bites, the T cells develop a stron …
The primary features of the alpha-gal syndrome (AGS) are (i) The IgE ab that are causally related to anaphylaxis with i …
Management of Food Allergies and Food-Related Anaphylaxis.
Iglesia EGA, Kwan M, Virkud YV, Iweala OI. Iglesia EGA, et al. JAMA. 2024 Feb 13;331(6):510-521. doi: 10.1001/jama.2023.26857. JAMA. 2024. PMID: 38349368 Free PMC article.
The fatality rate from anaphylaxis due to food in the US is estimated to be 0.04 per million per year. Alpha-gal syndrome, which is associated with tick bites, is a rising cause of IgE-mediated food anaphylaxis. ...IgE-mediated anaphylaxis to fo …
The fatality rate from anaphylaxis due to food in the US is estimated to be 0.04 per million per year. Alpha-gal syndrome …
186 results