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An effective method for the determination of the enantio-purity of L-α-glycerophosphocholine (L-α-GPC).
de Ferra L, Massa A, Di Mola A, Diehl B. de Ferra L, et al. J Pharm Biomed Anal. 2020 May 10;183:113152. doi: 10.1016/j.jpba.2020.113152. Epub 2020 Feb 8. J Pharm Biomed Anal. 2020. PMID: 32088520
Herein we describe for the first time a practical analytical method for determining the enantio-purity of L-alpha-glycerophosphocholine (L-alpha-GPC) by chiral derivatization. The use of a suitable chiral boronic acid allowed the formation of a mixture of two …
Herein we describe for the first time a practical analytical method for determining the enantio-purity of L-alpha-glycerophosphoch …
Anti-diabetic effect of S-adenosylmethionine and α-glycerophosphocholine in KK-Ay mice.
Izu H, Okuda M, Shibata S, Fujii T, Matsubara K. Izu H, et al. Biosci Biotechnol Biochem. 2019 Apr;83(4):747-750. doi: 10.1080/09168451.2018.1559721. Epub 2018 Dec 22. Biosci Biotechnol Biochem. 2019. PMID: 30582404
Six-week-old male KK-A(y) mice received drinking water with S-adenosylmethionine (SAM), alpha-glycerophosphocholine (GPC), or SAM+GPC for 10 weeks. The serum glucose of SAM+GPC at 15 weeks old, total cholesterol of GPC at 12 weeks old, and triglyceride of GPC at 15 …
Six-week-old male KK-A(y) mice received drinking water with S-adenosylmethionine (SAM), alpha-glycerophosphocholine (GPC), or …
Differential metabolism of choline supplements in adult volunteers.
Böckmann KA, Franz AR, Minarski M, Shunova A, Maiwald CA, Schwarz J, Gross M, Poets CF, Bernhard W. Böckmann KA, et al. Eur J Nutr. 2022 Feb;61(1):219-230. doi: 10.1007/s00394-021-02637-6. Epub 2021 Jul 21. Eur J Nutr. 2022. PMID: 34287673 Free PMC article. Clinical Trial.
Participants received a single dose of 550 mg/d choline equivalent in the form of choline chloride, choline bitartrate, alpha-glycerophosphocholine (GPC), and egg-PC in randomized sequence at least 1 week apart. ...
Participants received a single dose of 550 mg/d choline equivalent in the form of choline chloride, choline bitartrate, alpha-glyc …
L-alpha-glycerophosphocholine contributes to meat's enhancement of nonheme iron absorption.
Armah CN, Sharp P, Mellon FA, Pariagh S, Lund EK, Dainty JR, Teucher B, Fairweather-Tait SJ. Armah CN, et al. J Nutr. 2008 May;138(5):873-7. doi: 10.1093/jn/138.5.873. J Nutr. 2008. PMID: 18424594 Free article. Clinical Trial.
Tandem mass spectrometry was used to identify the compound as L-alpha-glycerophosphocholine (L-alpha) by comparing the spectra against authentic material. ...Nonheme iron absorption from lasagna was increased by the addition of either ascorbic acid (P = 0.010 …
Tandem mass spectrometry was used to identify the compound as L-alpha-glycerophosphocholine (L-alpha) by comparing the …
The delaying effect of alpha-glycerophosphocholine on senescence, transthyretin deposition, and osteoarthritis in senescence-accelerated mouse prone 8 mice.
Matsubara K, Okuda M, Shibata S, Miyaki S, Ohkubo T, Izu H, Fujii T. Matsubara K, et al. Biosci Biotechnol Biochem. 2018 Apr;82(4):647-653. doi: 10.1080/09168451.2017.1403883. Epub 2017 Dec 1. Biosci Biotechnol Biochem. 2018. PMID: 29191088
Administration of alpha-glycerophosphocholine (GPC), a choline compound in food, is expected to contribute to human health. ...
Administration of alpha-glycerophosphocholine (GPC), a choline compound in food, is expected to contribute to human health. .. …
alpha-Glycerophosphocholine in the mental recovery of cerebral ischemic attacks. An Italian multicenter clinical trial.
Barbagallo Sangiorgi G, Barbagallo M, Giordano M, Meli M, Panzarasa R. Barbagallo Sangiorgi G, et al. Ann N Y Acad Sci. 1994 Jun 30;717:253-69. doi: 10.1111/j.1749-6632.1994.tb12095.x. Ann N Y Acad Sci. 1994. PMID: 8030842 Clinical Trial.
The clinical efficacy and the tolerability of alpha-glycerophosphocholine (alpha-GPC), a drug able to provide high levels of choline for the nervous cells of the brain and to protect their cell walls, have been tested in a clinical open multicenter trial on 2 …
The clinical efficacy and the tolerability of alpha-glycerophosphocholine (alpha-GPC), a drug able to provide high leve …
Choline supplements: An update.
Kansakar U, Trimarco V, Mone P, Varzideh F, Lombardi A, Santulli G. Kansakar U, et al. Front Endocrinol (Lausanne). 2023 Mar 7;14:1148166. doi: 10.3389/fendo.2023.1148166. eCollection 2023. Front Endocrinol (Lausanne). 2023. PMID: 36950691 Free PMC article. Review.
In this comprehensive review, we examine the main preclinical and clinical investigations assessing the effects of different forms of choline supplementation currently available, including choline alfoscerate (C(8)H(20)NO(6)P), also known as alpha-glycerophosphocholine …
In this comprehensive review, we examine the main preclinical and clinical investigations assessing the effects of different forms of cholin …
Glycerophosphocholine enhances growth hormone secretion and fat oxidation in young adults.
Kawamura T, Okubo T, Sato K, Fujita S, Goto K, Hamaoka T, Iemitsu M. Kawamura T, et al. Nutrition. 2012 Nov-Dec;28(11-12):1122-6. doi: 10.1016/j.nut.2012.02.011. Epub 2012 Jun 5. Nutrition. 2012. PMID: 22673596 Clinical Trial.
OBJECTIVE: alpha-Glycerophosphocholine (GPC) is a putative acetylcholine precursor that potentially increases growth hormone secretion through the action of acetylcholine-stimulated catecholamine. ...
OBJECTIVE: alpha-Glycerophosphocholine (GPC) is a putative acetylcholine precursor that potentially increases growth hormone s …
Choline and choline-related nutrients in regular and preterm infant growth.
Bernhard W, Poets CF, Franz AR. Bernhard W, et al. Eur J Nutr. 2019 Apr;58(3):931-945. doi: 10.1007/s00394-018-1834-7. Epub 2018 Oct 8. Eur J Nutr. 2019. PMID: 30298207 Review.
The rapid decrease in plasma choline after premature birth suggests an untimely reduction in choline supply, as cellular uptake is proportional to plasma concentration. Supply via breast milk, with phosphocholine and alpha-glycerophosphocholine as its major choline …
The rapid decrease in plasma choline after premature birth suggests an untimely reduction in choline supply, as cellular uptake is proportio …
21 results