Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1970 2
1975 2
1976 2
1978 1
1980 1
1982 4
1983 3
1984 4
1985 6
1986 3
1987 7
1988 2
1989 12
1990 10
1991 10
1992 10
1993 16
1994 12
1995 14
1996 16
1997 19
1998 21
1999 15
2000 17
2001 20
2002 18
2003 24
2004 22
2005 25
2006 29
2007 15
2008 21
2009 27
2010 15
2011 26
2012 35
2013 29
2014 24
2015 29
2016 32
2017 33
2018 36
2019 32
2020 40
2021 40
2022 35
2023 25
2024 31
2025 36
2026 32

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

842 results

Results by year

Filters applied: . Clear all
Page 1
Impact of alpha-Linolenic Acid, the Vegetable omega-3 Fatty Acid, on Cardiovascular Disease and Cognition.
Sala-Vila A, Fleming J, Kris-Etherton P, Ros E. Sala-Vila A, et al. Adv Nutr. 2022 Oct 2;13(5):1584-1602. doi: 10.1093/advances/nmac016. Adv Nutr. 2022. PMID: 35170723 Free PMC article.
Given the evidence of the health benefits of plant-based diets and long-chain n-3 (omega-3) fatty acids, there is keen interest in better understanding the role of alpha-linolenic acid (ALA), a plant-derived n-3 fatty acid, on cardiometabolic diseases …
Given the evidence of the health benefits of plant-based diets and long-chain n-3 (omega-3) fatty acids, there is keen interest in better un …
Alpha-Linolenic Acid and Cardiovascular Events: A Narrative Review.
Bertoni C, Abodi M, D'Oria V, Milani GP, Agostoni C, Mazzocchi A. Bertoni C, et al. Int J Mol Sci. 2023 Sep 20;24(18):14319. doi: 10.3390/ijms241814319. Int J Mol Sci. 2023. PMID: 37762621 Free PMC article. Review.
One of the alternative systems to drug therapy to minimize the risk of CVDs is represented by alpha-linolenic acid (ALA), an essential fatty acid of the omega-3 series, known for its cholesterol-lowering effect. ...Concerning the lipid-lowering prevent …
One of the alternative systems to drug therapy to minimize the risk of CVDs is represented by alpha-linolenic acid (ALA …
Effect of Alpha-Linolenic Acid Supplementation on Cardiovascular Disease Risk Profile in Individuals with Obesity or Overweight: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Yin S, Xu H, Xia J, Lu Y, Xu D, Sun J, Wang Y, Liao W, Sun G. Yin S, et al. Adv Nutr. 2023 Nov;14(6):1644-1655. doi: 10.1016/j.advnut.2023.09.010. Epub 2023 Sep 29. Adv Nutr. 2023. PMID: 37778442 Free PMC article.
Overweight and obesity are highly prevalent worldwide and are associated with cardiovascular disease (CVD) risk factors, including systematic inflammation, dyslipidemia, and hypertension. Alpha-linolenic acid (ALA) is a plant-based essential polyunsaturated f …
Overweight and obesity are highly prevalent worldwide and are associated with cardiovascular disease (CVD) risk factors, including systemati …
Omega-3 fatty acids for the primary and secondary prevention of cardiovascular disease.
Abdelhamid AS, Brown TJ, Brainard JS, Biswas P, Thorpe GC, Moore HJ, Deane KH, Summerbell CD, Worthington HV, Song F, Hooper L. Abdelhamid AS, et al. Cochrane Database Syst Rev. 2020 Feb 29;3(3):CD003177. doi: 10.1002/14651858.CD003177.pub5. Cochrane Database Syst Rev. 2020. PMID: 32114706 Free PMC article.
BACKGROUND: Omega-3 polyunsaturated fatty acids from oily fish (long-chain omega-3 (LCn3)), including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)), as well as from plants (alpha-linolenic acid (ALA)) may benefit cardiovascular hea …
BACKGROUND: Omega-3 polyunsaturated fatty acids from oily fish (long-chain omega-3 (LCn3)), including eicosapentaenoic acid (EPA) and …
Current Insights into the Effects of Dietary alpha-Linolenic Acid Focusing on Alterations of Polyunsaturated Fatty Acid Profiles in Metabolic Syndrome.
Takić M, Ranković S, Girek Z, Pavlović S, Jovanović P, Jovanović V, Šarac I. Takić M, et al. Int J Mol Sci. 2024 Apr 30;25(9):4909. doi: 10.3390/ijms25094909. Int J Mol Sci. 2024. PMID: 38732139 Free PMC article. Review.
The plant-derived alpha-linolenic acid (ALA) is an essential n-3 acid highly susceptible to oxidation, present in oils of flaxseeds, walnuts, canola, perilla, soy, and chia. After ingestion, it can be incorporated in to body lipid pools (particularly …
The plant-derived alpha-linolenic acid (ALA) is an essential n-3 acid highly susceptible to oxidation, present i …
alpha-Linolenic Acid-Rich Flaxseed Oil Improves Polycystic Ovary Syndrome via Regulating Lipid Metabolism by GPR120-cAMP Pathway and Restoring Gut Microecology.
Li S, Wang T, Liu M, Ma T, Li Y, Liu J, Liu Y, Shen W, Ma J, Wang X, Han X, Wang H, Zhang X. Li S, et al. Mol Nutr Food Res. 2025 Oct;69(19):e70136. doi: 10.1002/mnfr.70136. Epub 2025 Jun 11. Mol Nutr Food Res. 2025. PMID: 40500964
Polycystic ovary syndrome (PCOS) is a common endocrine disorder that affects metabolic and reproductive health in women. alpha-Linolenic acid (ALA)-rich flaxseed oil as a dietary food has been suggested to offer potential therapeutic benefits in managing meta …
Polycystic ovary syndrome (PCOS) is a common endocrine disorder that affects metabolic and reproductive health in women. alpha-Lin
Omega-3 fatty acids for the primary and secondary prevention of cardiovascular disease.
Abdelhamid AS, Brown TJ, Brainard JS, Biswas P, Thorpe GC, Moore HJ, Deane KH, AlAbdulghafoor FK, Summerbell CD, Worthington HV, Song F, Hooper L. Abdelhamid AS, et al. Cochrane Database Syst Rev. 2018 Jul 18;7(7):CD003177. doi: 10.1002/14651858.CD003177.pub3. Cochrane Database Syst Rev. 2018. Update in: Cochrane Database Syst Rev. 2018 Nov 30;11:CD003177. doi: 10.1002/14651858.CD003177.pub4. PMID: 30019766 Free PMC article. Updated.
BACKGROUND: Researchers have suggested that omega-3 polyunsaturated fatty acids from oily fish (long-chain omega-3 (LCn3), including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)), as well as from plants (alpha-linolenic acid (ALA)) …
BACKGROUND: Researchers have suggested that omega-3 polyunsaturated fatty acids from oily fish (long-chain omega-3 (LCn3), including eicosap …
Alpha-linolenic acid regulates white adipose tissue lipolysis independent of background dietary protein.
Woods SE, Gonzalez-Soto M, King AN, Capel F, Wright DC, Mutch DM. Woods SE, et al. J Nutr Biochem. 2026 Mar;149:110185. doi: 10.1016/j.jnutbio.2025.110185. Epub 2025 Nov 13. J Nutr Biochem. 2026. PMID: 41241262 Free article.
White adipose tissue (WAT) is an endocrine organ essential for maintaining whole-body energy balance by regulating fatty acid uptake, storage, and release. Emerging evidence indicates that omega-3 fatty acids have a role in modulating WAT lipid metabolism. While most studi …
White adipose tissue (WAT) is an endocrine organ essential for maintaining whole-body energy balance by regulating fatty acid uptake, …
alpha-Linolenic acid and linoleic acid modulate the lipidome and the skin barrier of a tissue-engineered skin model.
Simard M, Tremblay A, Morin S, Martin C, Julien P, Fradette J, Flamand N, Pouliot R. Simard M, et al. Acta Biomater. 2022 Mar 1;140:261-274. doi: 10.1016/j.actbio.2021.11.021. Epub 2021 Nov 20. Acta Biomater. 2022. PMID: 34808417 Free article.
Skin substitutes were engineered according to the self-assembly method with a culture medium supplemented with 10 muM of both alpha-linolenic acid (ALA) and linoleic acid (LA). The supplementation with ALA and LA decreased testosterone absorption throu …
Skin substitutes were engineered according to the self-assembly method with a culture medium supplemented with 10 muM of both alpha- …
Effects of alpha-linolenic acid intake on blood lipid profiles:a systematic review and meta-analysis of randomized controlled trials.
Yue H, Qiu B, Jia M, Liu W, Guo XF, Li N, Xu ZX, Du FL, Xu T, Li D. Yue H, et al. Crit Rev Food Sci Nutr. 2021;61(17):2894-2910. doi: 10.1080/10408398.2020.1790496. Epub 2020 Jul 9. Crit Rev Food Sci Nutr. 2021. PMID: 32643951
To investigate the effect of ALA intake on blood lipid profiles, including triglycerides (TG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), very-low-density lipoprotein (VLDL-C) and ratio of TC to HDL-C. …
To investigate the effect of ALA intake on blood lipid profiles, including triglycerides (TG), total cholesterol (TC), high-density l …
842 results