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Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1980 2
1981 5
1982 2
1983 9
1984 5
1985 6
1986 8
1987 10
1988 11
1989 7
1990 22
1991 33
1992 24
1993 26
1994 26
1995 19
1996 12
1997 11
1998 16
1999 12
2000 9
2001 5
2002 4
2003 7
2004 8
2005 17
2006 8
2007 13
2008 8
2009 8
2010 5
2011 10
2012 11
2013 3
2014 11
2015 8
2016 4
2017 5
2018 6
2019 7
2020 6
2021 4
2022 5
2023 7
2024 2

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Search Results

429 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Alprazolam for depression.
van Marwijk H, Allick G, Wegman F, Bax A, Riphagen II. van Marwijk H, et al. Cochrane Database Syst Rev. 2012 Jul 11;2012(7):CD007139. doi: 10.1002/14651858.CD007139.pub2. Cochrane Database Syst Rev. 2012. PMID: 22786504 Free PMC article. Review.
We considered six studies to have a high risk of bias.When alprazolam was compared with placebo for reduction in symptoms all estimates indicated a positive effect for alprazolam. ...The RD of all-cause withdrawals was -0.04 (95% CI -0.07 to 0.00; I(2) = 35%), in fa …
We considered six studies to have a high risk of bias.When alprazolam was compared with placebo for reduction in symptoms all estimat …
Pharmacological treatments in panic disorder in adults: a network meta-analysis.
Guaiana G, Meader N, Barbui C, Davies SJ, Furukawa TA, Imai H, Dias S, Caldwell DM, Koesters M, Tajika A, Bighelli I, Pompoli A, Cipriani A, Dawson S, Robertson L. Guaiana G, et al. Cochrane Database Syst Rev. 2023 Nov 28;11(11):CD012729. doi: 10.1002/14651858.CD012729.pub3. Cochrane Database Syst Rev. 2023. PMID: 38014714 Free article. Review.
There is evidence from 48 RCTs (N = 10,118) that most medications are more effective in the response outcome than placebo. In particular, diazepam, alprazolam, clonazepam, paroxetine, venlafaxine, clomipramine, fluoxetine and adinazolam showed the strongest effect, with di …
There is evidence from 48 RCTs (N = 10,118) that most medications are more effective in the response outcome than placebo. In particular, di …
Age-related digoxin-alprazolam interaction.
Guven H, Tuncok Y, Guneri S, Cavdar C, Fowler J. Guven H, et al. Clin Pharmacol Ther. 1993 Jul;54(1):42-4. doi: 10.1038/clpt.1993.107. Clin Pharmacol Ther. 1993. PMID: 8330464 Clinical Trial.
A case report of dramatic increases in serum digoxin levels after alprazolam administration prompted our investigation. Twelve inpatients receiving long-term digoxin (0.25 mg daily) randomly received oral administration of either 1.0 or 0.5 mg alprazolam per day for …
A case report of dramatic increases in serum digoxin levels after alprazolam administration prompted our investigation. Twelve inpati …
Inhaled alprazolam rapidly suppresses epileptic activity in photosensitive participants.
French JA, Wechsler R, Gelfand MA, Pollard JR, Vazquez B, Friedman D, Gong LH, Kamemoto E, Isojarvi J, Cassella JV. French JA, et al. Epilepsia. 2019 Aug;60(8):1602-1609. doi: 10.1111/epi.16279. Epub 2019 Jul 3. Epilepsia. 2019. PMID: 31268555 Clinical Trial.
The AE profile of Staccato alprazolam was similar to what has been reported for alprazolam for other indications. The results support further development of Staccato alprazolam as a rescue medication for the acute treatment of seizures....
The AE profile of Staccato alprazolam was similar to what has been reported for alprazolam for other indications. The results …
GABAergic Effects of Etifoxine and Alprazolam Assessed by Double Pulse TMS.
Riebel M, von Pappenheim B, Kanig C, Nothdurfter C, Wetter TC, Rupprecht R, Schwarzbach J. Riebel M, et al. Pharmacopsychiatry. 2023 Jul;56(4):154-161. doi: 10.1055/a-2078-4823. Epub 2023 May 23. Pharmacopsychiatry. 2023. PMID: 37220781 Clinical Trial.
Alprazolam led to higher sedation and subjective impairment of concentration compared to etifoxine. ...The side effects and TMS profile of etifoxine are compatible with the involvement of neurosteroidogenesis and a predominant alpha3 subunit modulation compared to alpra
Alprazolam led to higher sedation and subjective impairment of concentration compared to etifoxine. ...The side effects and TMS profi
Alprazolam absorption kinetics affects abuse liability.
Mumford GK, Evans SM, Fleishaker JC, Griffiths RR. Mumford GK, et al. Clin Pharmacol Ther. 1995 Mar;57(3):356-65. doi: 10.1016/0009-9236(95)90162-0. Clin Pharmacol Ther. 1995. PMID: 7697954 Clinical Trial.
All subjects received placebo, 1 and 2 mg immediate-release alprazolam, and 2 and 3 mg extended-release alprazolam in random order. ...RESULTS: Mean peak alprazolam plasma concentrations occurred 1.7 and 9.2 hours after immediate-release alprazolam and …
All subjects received placebo, 1 and 2 mg immediate-release alprazolam, and 2 and 3 mg extended-release alprazolam in random o …
Alprazolam in end-stage renal disease: I. Pharmacokinetics.
Schmith VD, Piraino B, Smith RB, Kroboth PD. Schmith VD, et al. J Clin Pharmacol. 1991 Jun;31(6):571-9. doi: 10.1002/j.1552-4604.1991.tb03740.x. J Clin Pharmacol. 1991. PMID: 1880224 Clinical Trial.
Blood samples were collected over 48 hours after alprazolam 0.5 mg and alprazolam 2 mg administration. Alprazolam and alpha-hydroxyalprazolam concentrations and alprazolam free fraction were determined. ...Thus, end-stage renal disease is associated wi …
Blood samples were collected over 48 hours after alprazolam 0.5 mg and alprazolam 2 mg administration. Alprazolam and a …
Acute administration of alprazolam, alcohol and their combination on cognitive performance and mood: A randomised, double-blind, placebo-controlled study.
Aitken B, Hayley AC, Ford TC, Geier L, Shiferaw BA, Downey LA. Aitken B, et al. J Psychopharmacol. 2023 Dec;37(12):1227-1237. doi: 10.1177/02698811231200878. Epub 2023 Sep 19. J Psychopharmacol. 2023. PMID: 37724443 Free PMC article. Clinical Trial.
The most pronounced cognitive effects occurred at 100 min after dosing, coinciding with increased alprazolam concentrations. Sedative effects were heightened with alcohol, alprazolam and their combination while no stimulative effects were reported. CONCLUSIONS: Our …
The most pronounced cognitive effects occurred at 100 min after dosing, coinciding with increased alprazolam concentrations. Sedative …
Alprazolam-ritonavir interaction: implications for product labeling.
Greenblatt DJ, von Moltke LL, Harmatz JS, Durol AL, Daily JP, Graf JA, Mertzanis P, Hoffman JL, Shader RI. Greenblatt DJ, et al. Clin Pharmacol Ther. 2000 Apr;67(4):335-41. doi: 10.1067/mcp.2000.105757. Clin Pharmacol Ther. 2000. PMID: 10801241 Clinical Trial.
METHODS: The inhibitory effect of ritonavir on the metabolism of alprazolam, a CYP3A-mediated reaction in humans, was tested in vitro using human liver microsomes. In a double-blind clinical study, volunteer subjects received 1.0 mg of alprazolam concurrent with low …
METHODS: The inhibitory effect of ritonavir on the metabolism of alprazolam, a CYP3A-mediated reaction in humans, was tested in vitro …
Alprazolam in the treatment of neurotic anxiety.
Kerry RJ, McDermott CM. Kerry RJ, et al. Pharmatherapeutica. 1983;3(7):451-5. Pharmatherapeutica. 1983. PMID: 6142462 Clinical Trial.
A double-blind study was carried out in 30 hospital out-patients suffering from moderate to severe neurotic anxiety to compare the efficacy and tolerance of alprazolam and placebo. Patients were allocated at random to receive alprazolam, in a dosage of 0.5 to 1 mg 3 …
A double-blind study was carried out in 30 hospital out-patients suffering from moderate to severe neurotic anxiety to compare the efficacy …
429 results