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Year Number of Results
1982 3
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637 results

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Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Efficacy of Alprostadil in Preventing Contrast-Induced Nephropathy: A Systematic Review and Meta-Analysis.
Xu H, Wang H, Zhang C, Xiao J, Hua N, Tang X, Xie J, Zhang Z. Xu H, et al. Angiology. 2021 Oct;72(9):878-888. doi: 10.1177/00033197211004412. Epub 2021 Apr 15. Angiology. 2021. PMID: 33853365
We included 29 studies with 5623 patients. Compared with hydration, 10 g/d alprostadil or 20 g/d alprostadil plus hydration significantly decreased the incidence of CIN. ...Alprostadil plus hydration significantly decreased urine macroglobulin versus hydrat …
We included 29 studies with 5623 patients. Compared with hydration, 10 g/d alprostadil or 20 g/d alprostadil plus hydration …
Alprostadil for hypertensive nephropathy: A systematic review and meta-analysis of randomized controlled trials.
Fu H, Hou W, Zhang Y, Hu X. Fu H, et al. PLoS One. 2022 May 26;17(5):e0269111. doi: 10.1371/journal.pone.0269111. eCollection 2022. PLoS One. 2022. PMID: 35617324 Free PMC article.
Compared to conventional treatment alone, alprostadil combined with conventional treatment can improve renal function in patients with hypertensive nephropathy more effectively. ...This is the first meta-analysis to evaluate the efficacy of alprostadil for hypertens …
Compared to conventional treatment alone, alprostadil combined with conventional treatment can improve renal function in patients wit …
Efficacy of alprostadil for preventing of contrast-induced nephropathy: A meta-analysis.
Zhang JZ, Kang XJ, Gao Y, Zheng YY, Wu TT, Li L, Liu F, Yang YN, Li XM, Ma YT, Xie X. Zhang JZ, et al. Sci Rep. 2017 Apr 21;7(1):1045. doi: 10.1038/s41598-017-01160-1. Sci Rep. 2017. PMID: 28432310 Free PMC article.

Compared to the control group, the CIN risk decreased significantly in the alprostadil group (P < 0.00001, OR = 0.29, 95% CI = 0.21-0.39). In the subgroup of coronary angiography patients, the use of alprostadil also decreased the risk of CIN (P < 0.00001, OR

…

Compared to the control group, the CIN risk decreased significantly in the alprostadil group (P < 0.00001, OR = 0.29, 95% CI = 0.2

…
Effect of Alprostadil on the Prevention of Contrast-Induced Nephropathy: A Meta-Analysis of 36 Randomized Controlled Trials.
Xie J, Jiang M, Lin Y, Deng H, Li L. Xie J, et al. Angiology. 2019 Aug;70(7):594-612. doi: 10.1177/0003319719825597. Epub 2019 Jan 22. Angiology. 2019. PMID: 30669852 Review.
Contrast-induced nephropathy (CIN) is the third leading cause of acquired acute renal injury in hospitalized patients. Alprostadil plays a role in the maintenance and redistribution of intrarenal blood flow and the excretion of electrolytes and water. However, the effectiv …
Contrast-induced nephropathy (CIN) is the third leading cause of acquired acute renal injury in hospitalized patients. Alprostadil pl …
The effect of topical and intraurethral alprostadil on erectile function: A systematic review and meta-analysis.
Papadopoulos I, Tishukov M, Sokolakis I, Katafigiotis I, Leotsakos I, Karavitakis M, Marcon J, Stief CG, Pyrgidis N. Papadopoulos I, et al. Andrology. 2025 Nov;13(8):2235-2245. doi: 10.1111/andr.70025. Epub 2025 Mar 19. Andrology. 2025. PMID: 40105058 Free PMC article.
The meta-analysis showed a statistically significant improvement in the IIEF score by 4.7 points (95% CI: 2.4-7.1, I(2) = 97%) in patients using the topical form of alprostadil compared to placebo. There was also a statistically significant improvement of ED in patients us …
The meta-analysis showed a statistically significant improvement in the IIEF score by 4.7 points (95% CI: 2.4-7.1, I(2) = 97%) in patients u …
Efficacy and Safety of Alprostadil in Microcirculatory Disturbances During Emergency PCI: A Meta-Analysis of Randomized Controlled Trials.
Chen Y, Wang M, Yang Y, Zeng M. Chen Y, et al. Am J Cardiovasc Drugs. 2024 Jul;24(4):547-556. doi: 10.1007/s40256-024-00655-3. Epub 2024 Jun 8. Am J Cardiovasc Drugs. 2024. PMID: 38850398
OBJECTIVE: The clinical advantage of alprostadil [prostaglandin E1 (PGE1)] in the treatment of microcirculatory disturbances (defined as no-reflow or slow-flow) in acute percutaneous coronary intervention (PCI) is still disputed. ...
OBJECTIVE: The clinical advantage of alprostadil [prostaglandin E1 (PGE1)] in the treatment of microcirculatory disturbances (defined …
Application of Nanoliposome Alprostadil in the Perioperative Period of Percutaneous Coronary Intervention to Reduce In-Stent Restenosis: A Systematic Review and Meta-Analysis.
Zhu D, Wang D, Zhao Z, Liu Q, Yang R, Liu Q. Zhu D, et al. J Interv Cardiol. 2023 May 18;2023:4100197. doi: 10.1155/2023/4100197. eCollection 2023. J Interv Cardiol. 2023. PMID: 37251365 Free PMC article.
BACKGROUND: In-stent restenosis (ISR) is a common complication after percutaneous coronary intervention (PCI) surgery for patients with coronary atherosclerotic heart disease (CHD). Reports indicate alprostadil may reduce ISR, and this study aimed at reviewing and summariz …
BACKGROUND: In-stent restenosis (ISR) is a common complication after percutaneous coronary intervention (PCI) surgery for patients with coro …
Xuebijing injection combined with alprostadil in the treatment of diabetic nephropathy: A PRISMA-compliant systematic review and meta-analysis.
Hao N, Liu Y, Guo L, Li W, Zhao P. Hao N, et al. Medicine (Baltimore). 2024 Jun 14;103(24):e32095. doi: 10.1097/MD.0000000000032095. Medicine (Baltimore). 2024. PMID: 38875385 Free PMC article.
OBJECTIVE: The purpose of the research was to systematically evaluate the clinical efficacy of Xuebijing injection combined with alprostadil in the treatment of diabetic nephropathy. METHODS: We searched the China National Knowledge Infrastructure (CNKI), China Biomedical …
OBJECTIVE: The purpose of the research was to systematically evaluate the clinical efficacy of Xuebijing injection combined with alprosta …
Topical alprostadil cream for the treatment of erectile dysfunction: a combined analysis of the phase II program.
Steidle C, Padma-Nathan H, Salem S, Tayse N, Thwing D, Fendl J, Yeager J, Harning R. Steidle C, et al. Urology. 2002 Dec;60(6):1077-82. doi: 10.1016/s0090-4295(02)01980-5. Urology. 2002. PMID: 12475674 Clinical Trial.
OBJECTIVES: To present a meta-analysis of the efficacy and safety data of two recently completed Phase II studies examining a novel alprostadil topical cream for the treatment of erectile dysfunction (ED). METHODS: Patients (n = 303) with ED of at least 3 months' duration …
OBJECTIVES: To present a meta-analysis of the efficacy and safety data of two recently completed Phase II studies examining a novel alpro …
[Panax notoginseng extract combined with alprostadil in treatment of arteriosclerosis obliterans: Meta-analysis].
[No authors listed] [No authors listed] Zhongguo Zhong Yao Za Zhi. 2018 Apr;43(8):1701-1707. doi: 10.19540/j.cnki.cjcmm.20180112.002. Zhongguo Zhong Yao Za Zhi. 2018. PMID: 29751719 Chinese.
To evaluate the clinical efficacy of Panax notoginseng extract combined with alprostadil in the treatment of arteriosclerosis occlusion and investigate its effects on the degree of atherosclerosis. ...Analysis results showed that the P. notoginseng extract combined with …
To evaluate the clinical efficacy of Panax notoginseng extract combined with alprostadil in the treatment of arteriosclerosis occlusi …
637 results