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626 results

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Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Effect of Alprostadil on the Prevention of Contrast-Induced Nephropathy: A Meta-Analysis of 36 Randomized Controlled Trials.
Xie J, Jiang M, Lin Y, Deng H, Li L. Xie J, et al. Angiology. 2019 Aug;70(7):594-612. doi: 10.1177/0003319719825597. Epub 2019 Jan 22. Angiology. 2019. PMID: 30669852 Review.
Contrast-induced nephropathy (CIN) is the third leading cause of acquired acute renal injury in hospitalized patients. Alprostadil plays a role in the maintenance and redistribution of intrarenal blood flow and the excretion of electrolytes and water. However, the effectiv …
Contrast-induced nephropathy (CIN) is the third leading cause of acquired acute renal injury in hospitalized patients. Alprostadil pl …
Alprostadil for hypertensive nephropathy: A systematic review and meta-analysis of randomized controlled trials.
Fu H, Hou W, Zhang Y, Hu X. Fu H, et al. PLoS One. 2022 May 26;17(5):e0269111. doi: 10.1371/journal.pone.0269111. eCollection 2022. PLoS One. 2022. PMID: 35617324 Free PMC article.
Compared to conventional treatment alone, alprostadil combined with conventional treatment can improve renal function in patients with hypertensive nephropathy more effectively. ...This is the first meta-analysis to evaluate the efficacy of alprostadil for hypertens …
Compared to conventional treatment alone, alprostadil combined with conventional treatment can improve renal function in patients wit …
Efficacy of Alprostadil in Preventing Contrast-Induced Nephropathy: A Systematic Review and Meta-Analysis.
Xu H, Wang H, Zhang C, Xiao J, Hua N, Tang X, Xie J, Zhang Z. Xu H, et al. Angiology. 2021 Oct;72(9):878-888. doi: 10.1177/00033197211004412. Epub 2021 Apr 15. Angiology. 2021. PMID: 33853365
We included 29 studies with 5623 patients. Compared with hydration, 10 g/d alprostadil or 20 g/d alprostadil plus hydration significantly decreased the incidence of CIN. ...Alprostadil plus hydration significantly decreased urine macroglobulin versus hydratio …
We included 29 studies with 5623 patients. Compared with hydration, 10 g/d alprostadil or 20 g/d alprostadil plus hydration si …
The effect of alprostadil on preventing contrast-induced nephropathy for percutaneous coronary intervention in diabetic patients: A systematic review and meta-analysis.
Ye Z, Lu H, Guo W, Dai W, Li H, Yang H, Li L. Ye Z, et al. Medicine (Baltimore). 2016 Nov;95(46):e5306. doi: 10.1097/MD.0000000000005306. Medicine (Baltimore). 2016. PMID: 27861357 Free PMC article. Review.
METHODS: An electronic database search was conducted in MEDLINE, Embase, Cochrane library, CBM, CNKI, VIP, and WanFang to retrieve randomized controlled trial (RCT) comparing Alprostadil versus hydration on preventing CIN for PCI in diabetic patients. Reference lists of re …
METHODS: An electronic database search was conducted in MEDLINE, Embase, Cochrane library, CBM, CNKI, VIP, and WanFang to retrieve randomize …
Alprostadil protects type 2 diabetes mellitus patients treated with metformin from contrast-induced nephropathy.
Wang J, Ai X, Li L, Gao Y, Sun N, Li C, Sun W. Wang J, et al. Int Urol Nephrol. 2017 Nov;49(11):2019-2026. doi: 10.1007/s11255-017-1639-2. Epub 2017 Jun 27. Int Urol Nephrol. 2017. PMID: 28656510 Clinical Trial.
METHODS: In this single-institution, single-blind, superiority trial, we randomly assigned 451 T2DM patients taking metformin and underwent emergency contrast-enhanced CT examination to either the alprostadil group (227 patients) receiving alprostadil or the control …
METHODS: In this single-institution, single-blind, superiority trial, we randomly assigned 451 T2DM patients taking metformin and underwent …
The Preventive Effect of Alprostadil on the Contrast-Induced Nephropathy of Coronary Heart Disease Treated by Percutaneous Coronary Intervention in Moderate and High-Risk Population Stratified by Mehran Score.
Liu X, Zhang P, Zhang J, Zhang X, Yang S, Fu N. Liu X, et al. Angiology. 2022 Jan;73(1):33-41. doi: 10.1177/00033197211015540. Epub 2021 Jun 8. Angiology. 2022. PMID: 34098771 Clinical Trial.
Alprostadil can be used as a preventive treatment for moderate- and high-risk CIN patients classified by the MRS. The reduction of CIN by alprostadil may be related to an anti-inflammatory effect....
Alprostadil can be used as a preventive treatment for moderate- and high-risk CIN patients classified by the MRS. The reduction of CI
Efficacy of alprostadil for preventing of contrast-induced nephropathy: A meta-analysis.
Zhang JZ, Kang XJ, Gao Y, Zheng YY, Wu TT, Li L, Liu F, Yang YN, Li XM, Ma YT, Xie X. Zhang JZ, et al. Sci Rep. 2017 Apr 21;7(1):1045. doi: 10.1038/s41598-017-01160-1. Sci Rep. 2017. PMID: 28432310 Free PMC article.

Compared to the control group, the CIN risk decreased significantly in the alprostadil group (P < 0.00001, OR = 0.29, 95% CI = 0.21-0.39). In the subgroup of coronary angiography patients, the use of alprostadil also decreased the risk of CIN (P < 0.00001, OR

Compared to the control group, the CIN risk decreased significantly in the alprostadil group (P < 0.00001, OR = 0.29, 95% CI = 0.2

Is topical alprostadil an usable and reliable alternative to intracavernous injection for penile dynamic duplex ultrasonography?
Arcaniolo D, Bellastella G, Manfredi C, Terribile M, Giordano DR, Quattrone C, La Rocca R, De Sio M, Verze P, Mirone V. Arcaniolo D, et al. Andrologia. 2020 Mar;52(2):e13480. doi: 10.1111/and.13480. Epub 2019 Nov 11. Andrologia. 2020. PMID: 31710398 Clinical Trial.
No study has yet been done to evaluate topical alprostadil as a less invasive alternative vasoactive agent for Penile Dynamic Duplex Ultrasonography (PDDU) in the diagnosis of erectile dysfunction. ...Patients reported less pain/discomfort during the procedure in case of t …
No study has yet been done to evaluate topical alprostadil as a less invasive alternative vasoactive agent for Penile Dynamic Duplex …
Effects of alprostadil combined with tanshinone IIa injection on microcirculation disorder, outcomes, and cardiac function in AMI patients after PCI.
Lu Y, Yan Y, Liu X. Lu Y, et al. Ann Palliat Med. 2021 Jan;10(1):97-103. doi: 10.21037/apm-20-2147. Ann Palliat Med. 2021. PMID: 33545751 Free article. Clinical Trial.
BACKGROUND: Alprostadil can effectively dilate blood vessels, improve cardiac microcirculation, and reduce cardiac load. ...CONCLUSIONS: For AMI patients after PCI, alprostadil combined with tanshinone IIa injection can effectively improve microcirculation and ventr …
BACKGROUND: Alprostadil can effectively dilate blood vessels, improve cardiac microcirculation, and reduce cardiac load. ...CONCLUSIO …
626 results