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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1965 1
1968 1
1973 2
1975 2
1976 4
1977 1
1978 2
1979 5
1980 7
1981 6
1982 8
1983 13
1984 4
1985 20
1986 25
1987 23
1988 25
1989 40
1990 44
1991 48
1992 50
1993 53
1994 38
1995 34
1996 29
1997 25
1998 37
1999 23
2000 28
2001 33
2002 25
2003 22
2004 21
2005 18
2006 34
2007 33
2008 26
2009 27
2010 23
2011 33
2012 38
2013 45
2014 49
2015 51
2016 50
2017 52
2018 51
2019 57
2020 73
2021 83
2022 88
2023 94
2024 32

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1,526 results

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Page 1
Effects of Cycloastragenol on Alzheimer's Disease in Rats by Reducing Oxidative Stress, Inflammation, and Apoptosis.
Alharbi KM, Alshehri SA, Almarwani WA, Aljohani KK, Albalawi AZ, Alatawi AS, Al-Atwi SM, Alhwyty LS, Hassan HM, Al-Gayyar MMH. Alharbi KM, et al. Curr Alzheimer Res. 2024 May 17. doi: 10.2174/0115672050315334240508162754. Online ahead of print. Curr Alzheimer Res. 2024. PMID: 38766828
BACKGROUND: As individuals age, they may develop Alzheimer's disease (AD), which is characterized by difficulties in speech, memory loss, and other issues related to neural function. Cycloastragenol is an active ingredient of Astragalus trojanus and has been …
BACKGROUND: As individuals age, they may develop Alzheimer's disease (AD), which is characterized by difficulties in sp …
Betanin combined with virgin coconut oil inhibits neuroinflammation in aluminum chloride-induced toxicity in rats by regulating NLRP3 inflammasome.
Thawkar BS, Kaur G. Thawkar BS, et al. J Tradit Complement Med. 2023 Nov 11;14(3):287-299. doi: 10.1016/j.jtcme.2023.11.001. eCollection 2024 May. J Tradit Complement Med. 2023. PMID: 38707915 Free PMC article.
BACKGROUND AND AIM: Activating NLRP3 (NOD-, LRR-, and pyrin domain-containing protein 3) is crucial in the pathogenesis of Alzheimer's disease (AD). A multimodal treatment intervention is the most feasible way to alter the course of AD progression. Hence, the …
BACKGROUND AND AIM: Activating NLRP3 (NOD-, LRR-, and pyrin domain-containing protein 3) is crucial in the pathogenesis of Alzheimer' …
"Time Saved" Calculations to Improve Decision-Making in Progressive Disease Studies.
Dickson SP, Haaland B, Mallinckrodt CH, Dubois B, O'Keefe P, Morgan M, Peters O, Fernández Santana Iii A, Harrison J, Schneeberger A, Hendrix S. Dickson SP, et al. J Prev Alzheimers Dis. 2024;11(3):529-536. doi: 10.14283/jpad.2024.64. J Prev Alzheimers Dis. 2024. PMID: 38706269 Free PMC article. Clinical Trial.
BACKGROUND: Disease modifying therapies (DMTs) may be most beneficial in early disease, when progression is slow and changes small, with clinical relevance difficult to interpret. ...SETTING: TCT methods were applied to a randomized phase II clinical trial. PARTICIP …
BACKGROUND: Disease modifying therapies (DMTs) may be most beneficial in early disease, when progression is slow and changes s …
Trace Elements in Alzheimer's Disease and Dementia: The Current State of Knowledge.
Tyczyńska M, Gędek M, Brachet A, Stręk W, Flieger J, Teresiński G, Baj J. Tyczyńska M, et al. J Clin Med. 2024 Apr 19;13(8):2381. doi: 10.3390/jcm13082381. J Clin Med. 2024. PMID: 38673657 Free PMC article. Review.
Changes in trace element concentrations are being wildly considered when it comes to neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease. This study aims to present the role that trace elements play in the central nervous s …
Changes in trace element concentrations are being wildly considered when it comes to neurodegenerative disorders, such as Alzheimer' …
Effect of thymol on oxidative stress and reelin signaling pathway in Alzheimer's disease model.
Bitmez B, Çevreli B, Kaşikçi E. Bitmez B, et al. Turk J Biol. 2024 Feb 1;48(1):70-79. doi: 10.55730/1300-0152.2683. eCollection 2024. Turk J Biol. 2024. PMID: 38665779 Free PMC article.
Thymol reduced working memory errors (WME), reference memory errors (RME), and maze completion time at 48, 72, and 96 hours when evaluated in terms of spatial memory in rats with Alzheimer's disease. Furthermore, Abeta(1-42) and ApoE levels were increased in …
Thymol reduced working memory errors (WME), reference memory errors (RME), and maze completion time at 48, 72, and 96 hours when evaluated i …
Ameliorative anti-coagulant, anti-oxidative and anti-ferroptotic activities of nanocurcumin and donepezil on coagulation, oxidation and ferroptosis in Alzheimer's disease.
Nawar NF, Beltagy DM, Mohamed TM, Tousson E, El-Keey MM. Nawar NF, et al. Toxicol Res (Camb). 2024 Apr 10;13(2):tfae054. doi: 10.1093/toxres/tfae054. eCollection 2024 Apr. Toxicol Res (Camb). 2024. PMID: 38617712
Alzheimer's disease (ad) is a neurological condition that worsens over time and is characterized by the buildup of amyloid (Abeta) plaques in the brain parenchyma. ...The objective of the current investigation was to examine the neuroprotective and anti-ferro
Alzheimer's disease (ad) is a neurological condition that worsens over time and is characterized by the buildup of amyl
Association between the Composition of Drinking Water and Cognitive Function in the Elderly: A Systematic Review.
Wasick A, Kim Y. Wasick A, et al. Int J Environ Res Public Health. 2024 Mar 19;21(3):362. doi: 10.3390/ijerph21030362. Int J Environ Res Public Health. 2024. PMID: 38541362 Free PMC article.
The prevalence of dementia increases with nearly 10 million new cases each year, with Alzheimer's disease contributing to 60-70% of cases. Environmental factors such as drinking water have been evaluated to determine if a relationship exists between trace ele …
The prevalence of dementia increases with nearly 10 million new cases each year, with Alzheimer's disease contributing …
Neuroprotective effect of taxifolin against aluminum chloride-induced dementia and pathological alterations in the brain of rats: possible involvement of toll-like receptor 4.
Saxena B, Parmar P, Chauhan H, Singh P, Datusalia AK, Vyas VK, Tripathi N, Shah J. Saxena B, et al. Toxicol Mech Methods. 2024 Mar 25:1-14. doi: 10.1080/15376516.2024.2329653. Online ahead of print. Toxicol Mech Methods. 2024. PMID: 38465425
Aluminum (Al) overexposure damages various organ systems, especially the nervous system. Regularly administered aluminum chloride (AlCl(3)) to rats causes dementia and pathophysiological alterations linked to Alzheimer's disease (AD). ...
Aluminum (Al) overexposure damages various organ systems, especially the nervous system. Regularly administered aluminum chlor
3-Acetyl coumarin alleviate neuroinflammatory responses and oxidative stress in aluminum chloride-induced Alzheimer's disease rat model.
Zeb Z, Sharif A, Akhtar B, Shahnaz. Zeb Z, et al. Inflammopharmacology. 2024 Apr;32(2):1371-1386. doi: 10.1007/s10787-024-01434-x. Epub 2024 Mar 6. Inflammopharmacology. 2024. PMID: 38448794
Alzheimer's disease (AD) is a neurodegenerative disorder that impairs mental ability and interrupts cognitive function. Heavy metal exposure like aluminum chloride is associated with neurotoxicity linked to neuro-inflammation, oxidative stress, accumul
Alzheimer's disease (AD) is a neurodegenerative disorder that impairs mental ability and interrupts cognitive function.
Protective effects of myricetin and morin on neurological damage in Abeta(1-42)/Al(3+) -induced Alzheimer's disease model of rats.
Guo L, Zhao Y, Kong Z, Liu R, Liu P. Guo L, et al. J Chem Neuroanat. 2024 Apr;137:102404. doi: 10.1016/j.jchemneu.2024.102404. Epub 2024 Feb 27. J Chem Neuroanat. 2024. PMID: 38423257
Alzheimer's disease (AD) is a degenerative neurological disorder with unclear pathogenesis. ...In this study, we used microinjection of Abeta(1-42) oligomers into the CA1 region of rat hippocampus, combined with gavage of Aluminum chloride hexahydrate
Alzheimer's disease (AD) is a degenerative neurological disorder with unclear pathogenesis. ...In this study, we used m
1,526 results