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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1996 1
2001 1
2002 3
2003 1
2004 1
2005 2
2009 1
2011 1
2013 1
2014 1
2015 2
2016 2
2017 1
2018 7
2019 8
2020 5
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34 results
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Decreased HHV-6 IgG in Alzheimer's Disease.
Westman G, Blomberg J, Yun Z, Lannfelt L, Ingelsson M, Eriksson BM. Westman G, et al. Front Neurol. 2017 Feb 20;8:40. doi: 10.3389/fneur.2017.00040. eCollection 2017. Front Neurol. 2017. PMID: 28265256 Free PMC article.
Human herpesviruses have previously been implicated in the pathogenesis of Alzheimer's disease (AD) but whether they are causal, facilitating, or confounding factors is yet to be established. A total of 50 AD subjects and 52 non-demented (ND) controls
Human herpesviruses have previously been implicated in the pathogenesis of Alzheimer's disease (AD) but whether
Alzheimer's Disease-Associated β-Amyloid Is Rapidly Seeded by Herpesviridae to Protect against Brain Infection.
Eimer WA, Vijaya Kumar DK, Navalpur Shanmugam NK, Rodriguez AS, Mitchell T, Washicosky KJ, György B, Breakefield XO, Tanzi RE, Moir RD. Eimer WA, et al. Neuron. 2018 Jul 11;99(1):56-63.e3. doi: 10.1016/j.neuron.2018.06.030. Neuron. 2018. PMID: 30001512 Free PMC article.
Amyloid-β peptide (Aβ) fibrilization and deposition as β-amyloid are hallmarks of Alzheimer's disease (AD) pathology. We recently reported Aβ is an innate immune protein that protects against fungal and bacterial infections. ...Here, we show Aβ oligomers bind …
Amyloid-β peptide (Aβ) fibrilization and deposition as β-amyloid are hallmarks of Alzheimer's disease (AD) pathology. W …
Multiscale Analysis of Independent Alzheimer's Cohorts Finds Disruption of Molecular, Genetic, and Clinical Networks by Human Herpesvirus.
Readhead B, Haure-Mirande JV, Funk CC, Richards MA, Shannon P, Haroutunian V, Sano M, Liang WS, Beckmann ND, Price ND, Reiman EM, Schadt EE, Ehrlich ME, Gandy S, Dudley JT. Readhead B, et al. Neuron. 2018 Jul 11;99(1):64-82.e7. doi: 10.1016/j.neuron.2018.05.023. Epub 2018 Jun 21. Neuron. 2018. PMID: 29937276 Free PMC article.
Investigators have long suspected that pathogenic microbes might contribute to the onset and progression of Alzheimer's disease (AD) although definitive evidence has not been presented. ...We observed increased human herpesvirus 6A (HHV-6 …
Investigators have long suspected that pathogenic microbes might contribute to the onset and progression of Alzheimer's dis
Microbes and Alzheimer's Disease: New Findings Call for a Paradigm Change.
Haas JG, Lathe R. Haas JG, et al. Trends Neurosci. 2018 Sep;41(9):570-573. doi: 10.1016/j.tins.2018.07.001. Epub 2018 Jul 19. Trends Neurosci. 2018. PMID: 30033181
Two papers in Neuron provide compelling new indications of a link between herpesviruses and Alzheimer's disease (AD). Readhead et al. report an increased abundance of human herpesviruses 6A and 7 (HHV-6A/7) in AD brain, whereas Eimer et al. show …
Two papers in Neuron provide compelling new indications of a link between herpesviruses and Alzheimer's disease (AD). R …
Lack of evidence for a role of HHV-6 in the pathogenesis of Alzheimer's disease.
Agostini S, Mancuso R, Baglio F, Cabinio M, Hernis A, Guerini FR, Calabrese E, Nemni R, Clerici M. Agostini S, et al. J Alzheimers Dis. 2016;49(1):229-35. doi: 10.3233/JAD-150464. J Alzheimers Dis. 2016. PMID: 26444787
BACKGROUND: Alzheimer's disease (AD), the most common form of dementia worldwide, is associated with impairment in the mechanisms of the clearing of amyloid-β within a scenario of neuroinflammation. ...Serum HHV-6 IgG antibody titers and avidity …
BACKGROUND: Alzheimer's disease (AD), the most common form of dementia worldwide, is associated with impairment in the …
Human Herpesvirus 6 Detection in Alzheimer's Disease Cases and Controls across Multiple Cohorts.
Allnutt MA, Johnson K, Bennett DA, Connor SM, Troncoso JC, Pletnikova O, Albert MS, Resnick SM, Scholz SW, De Jager PL, Jacobson S. Allnutt MA, et al. Neuron. 2020 Mar 18;105(6):1027-1035.e2. doi: 10.1016/j.neuron.2019.12.031. Epub 2020 Jan 23. Neuron. 2020. PMID: 31983538
The interplay between viral infection and Alzheimer's disease (AD) has long been an area of interest, but proving causality has been elusive. Several recent studies have renewed the debate concerning the role of herpesviruses, and human herpesvirus
The interplay between viral infection and Alzheimer's disease (AD) has long been an area of interest, but proving causa …
Common Infections May Lead to Alzheimer's Disease.
Wang Y, Ding L, Zhu Q, Shu M, Cai Q. Wang Y, et al. Virol Sin. 2018 Oct;33(5):456-458. doi: 10.1007/s12250-018-0049-7. Epub 2018 Sep 17. Virol Sin. 2018. PMID: 30225586 Free PMC article. No abstract available.
Are HHV-6A and HHV-7 Really More Abundant in Alzheimer's Disease?
Jeong HH, Liu Z. Jeong HH, et al. Neuron. 2019 Dec 18;104(6):1034-1035. doi: 10.1016/j.neuron.2019.11.009. Neuron. 2019. PMID: 31855626 No abstract available.
Herpes virus in Alzheimer's disease: relation to progression of the disease.
Carbone I, Lazzarotto T, Ianni M, Porcellini E, Forti P, Masliah E, Gabrielli L, Licastro F. Carbone I, et al. Neurobiol Aging. 2014 Jan;35(1):122-9. doi: 10.1016/j.neurobiolaging.2013.06.024. Epub 2013 Aug 3. Neurobiol Aging. 2014. PMID: 23916950
Studies regarding different viruses of the herpes family, such as cytomegalovirus (CMV), Epstein-Barr virus (EBV), or human herpes virus 6 (HHV-6) in Alzheimer's disease (AD) are scarce. ...HHV-6 showed a 23% positivi …
Studies regarding different viruses of the herpes family, such as cytomegalovirus (CMV), Epstein-Barr virus (EBV), or human herpes vi …
HHV-6A infection dysregulates autophagy/UPR interplay increasing beta amyloid production and tau phosphorylation in astrocytoma cells as well as in primary neurons, possible molecular mechanisms linking viral infection to Alzheimer's disease.
Romeo MA, Gilardini Montani MS, Gaeta A, D'Orazi G, Faggioni A, Cirone M. Romeo MA, et al. Biochim Biophys Acta Mol Basis Dis. 2020 Mar 1;1866(3):165647. doi: 10.1016/j.bbadis.2019.165647. Epub 2019 Dec 19. Biochim Biophys Acta Mol Basis Dis. 2020. PMID: 31866416
HHV-6A and HHV-6B are neurotropic viruses able to dysregulate autophagy and activate ER stress/UPR in several cell types. The appropriate functioning of these processes is required for cell homeostasis, particularly in post-mitotic cells such as neuronal cells. Inte
HHV-6A and HHV-6B are neurotropic viruses able to dysregulate autophagy and activate ER stress/UPR in several cell types. The
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