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Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1969 2
1970 9
1971 5
1972 4
1973 2
1974 2
1975 2
1976 2
1979 2
1980 2
1981 3
1982 3
1983 3
1984 2
1985 2
1986 1
1987 6
1988 1
1989 4
1990 1
1991 5
1992 7
1993 4
1994 1
1995 9
1996 6
1997 2
1998 6
1999 9
2000 11
2001 15
2002 11
2003 20
2004 24
2005 23
2006 31
2007 30
2008 29
2009 22
2010 31
2011 25
2012 40
2013 35
2014 39
2015 34
2016 23
2017 36
2018 30
2019 28
2020 24
2021 15
2022 21
2023 14
2024 16
2025 32
2026 7

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Search Results

702 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Placebo-controlled trial of amantadine for severe traumatic brain injury.
Giacino JT, Whyte J, Bagiella E, Kalmar K, Childs N, Khademi A, Eifert B, Long D, Katz DI, Cho S, Yablon SA, Luther M, Hammond FM, Nordenbo A, Novak P, Mercer W, Maurer-Karattup P, Sherer M. Giacino JT, et al. N Engl J Med. 2012 Mar 1;366(9):819-26. doi: 10.1056/NEJMoa1102609. N Engl J Med. 2012. PMID: 22375973 Free article. Clinical Trial.
BACKGROUND: Amantadine hydrochloride is one of the most commonly prescribed medications for patients with prolonged disorders of consciousness after traumatic brain injury. ...Patients were randomly assigned to receive amantadine or placebo for 4 weeks and were foll …
BACKGROUND: Amantadine hydrochloride is one of the most commonly prescribed medications for patients with prolonged disorders of cons …
Amantadine and rimantadine for influenza A in adults.
Jefferson T, Demicheli V, Di Pietrantonj C, Rivetti D. Jefferson T, et al. Cochrane Database Syst Rev. 2006 Apr 19;2006(2):CD001169. doi: 10.1002/14651858.CD001169.pub3. Cochrane Database Syst Rev. 2006. PMID: 16625539 Free PMC article.
SELECTION CRITERIA: Randomised and quasi-randomised studies comparing amantadine and/or rimantadine with placebo, control medication or no intervention, or comparing doses or schedules of amantadine and/or rimantadine in healthy adults. ...Both amantadine and …
SELECTION CRITERIA: Randomised and quasi-randomised studies comparing amantadine and/or rimantadine with placebo, control medication …
Amantadine and rimantadine for influenza A in children and the elderly.
Alves Galvão MG, Rocha Crispino Santos MA, Alves da Cunha AJ. Alves Galvão MG, et al. Cochrane Database Syst Rev. 2014 Nov 21;2014(11):CD002745. doi: 10.1002/14651858.CD002745.pub4. Cochrane Database Syst Rev. 2014. PMID: 25415374 Free PMC article.
SELECTION CRITERIA: Randomised controlled trials (RCTs) or quasi-RCTs comparing amantadine and/or rimantadine with no intervention, placebo, other antivirals or different doses or schedules of amantadine or rimantadine in children and the elderly with influenza A. . …
SELECTION CRITERIA: Randomised controlled trials (RCTs) or quasi-RCTs comparing amantadine and/or rimantadine with no intervention, p …
Amantadine for Antipsychotic-Related Weight Gain: Meta-Analysis of Randomized Placebo-Controlled Trials.
Zheng W, Wang S, Ungvari GS, Ng CH, Yang XH, Gu YH, Li M, Xiang YQ, Xiang YT. Zheng W, et al. J Clin Psychopharmacol. 2017 Jun;37(3):341-346. doi: 10.1097/JCP.0000000000000598. J Clin Psychopharmacol. 2017. PMID: 28383359
This meta-analysis examined the efficacy and safety of amantadine as an adjunctive treatment of weight gain in schizophrenia by systematically searching and analyzing randomized controlled trials (RCTs). RCTs comparing adjunctive amantadine with placebo in adult pat …
This meta-analysis examined the efficacy and safety of amantadine as an adjunctive treatment of weight gain in schizophrenia by syste …
Assessment of the effect of amantadine in patients with traumatic brain injury: A meta-analysis.
Mohamed MS, El Sayed I, Zaki A, Abdelmonem S. Mohamed MS, et al. J Trauma Acute Care Surg. 2022 Mar 1;92(3):605-614. doi: 10.1097/TA.0000000000003363. J Trauma Acute Care Surg. 2022. PMID: 34284464
Metaregression of the different clinical parameters, which are onset of treatment, age, and severity of traumatic brain injury, showed a statistically significant relation between onset of treatment and the effect size of amantadine. The relation between the other two para …
Metaregression of the different clinical parameters, which are onset of treatment, age, and severity of traumatic brain injury, showed a sta …
Hippocampal Avoidance During Whole-Brain Radiotherapy Plus Memantine for Patients With Brain Metastases: Phase III Trial NRG Oncology CC001.
Brown PD, Gondi V, Pugh S, Tome WA, Wefel JS, Armstrong TS, Bovi JA, Robinson C, Konski A, Khuntia D, Grosshans D, Benzinger TLS, Bruner D, Gilbert MR, Roberge D, Kundapur V, Devisetty K, Shah S, Usuki K, Anderson BM, Stea B, Yoon H, Li J, Laack NN, Kruser TJ, Chmura SJ, Shi W, Deshmukh S, Mehta MP, Kachnic LA; for NRG Oncology. Brown PD, et al. J Clin Oncol. 2020 Apr 1;38(10):1019-1029. doi: 10.1200/JCO.19.02767. Epub 2020 Feb 14. J Clin Oncol. 2020. PMID: 32058845 Free PMC article. Clinical Trial.
Efficacy and safety of amantadine for functional recovery in adults with traumatic brain injuries: A comprehensive systematic review and meta-analysis.
Grüdtner DOM, Rocha JP, Monteiro MD, Mazon J, Silveira GSB, Koerbel A. Grüdtner DOM, et al. Clin Neurol Neurosurg. 2025 Oct;257:109084. doi: 10.1016/j.clineuro.2025.109084. Epub 2025 Jul 28. Clin Neurol Neurosurg. 2025. PMID: 40753790
BACKGROUND: Amantadine is a dopaminergic agonist with neuroprotective and neurostimulant properties. ...In a sensitivity analysis of the RCTs that assessed amantadine's effects in the first 6 weeks of treatment, a significant difference was found favoring amantad …
BACKGROUND: Amantadine is a dopaminergic agonist with neuroprotective and neurostimulant properties. ...In a sensitivity analysis of …
Evaluation of amantadine in chronic hepatitis C: a meta-analysis.
Deltenre P, Henrion J, Canva V, Dharancy S, Texier F, Louvet A, De Maeght S, Paris JC, Mathurin P. Deltenre P, et al. J Hepatol. 2004 Sep;41(3):462-73. doi: 10.1016/j.jhep.2004.05.019. J Hepatol. 2004. PMID: 15336450
In subgroup analysis, amantadine did not have a significant effect upon naive patients or relapsers. In non-responders, combination therapy with amantadine was associated with a significant effect on the sustained response (mean difference: 8.3%, 95% CI: 1.9-14.6%, …
In subgroup analysis, amantadine did not have a significant effect upon naive patients or relapsers. In non-responders, combination t …
Amantadine in depression.
Vale S, Espejel MA, Dominguez JC. Vale S, et al. Lancet. 1971 Aug 21;2(7721):437. doi: 10.1016/s0140-6736(71)90153-x. Lancet. 1971. PMID: 4105209 Clinical Trial. No abstract available.
702 results