Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1978 1
1981 2
1983 1
1984 1
1985 1
1986 4
1987 9
1988 3
1989 1
1990 2
1991 1
1992 1
1993 2
1994 1
1995 3
1996 1
1997 1
1999 1
2000 2
2001 3
2002 2
2003 2
2004 4
2006 2
2007 2
2008 2
2009 5
2010 7
2011 1
2012 5
2013 3
2014 8
2015 7
2016 4
2017 2
2018 4
2019 1
2020 2
2021 2
2022 1
2023 4
2024 2
2025 5
2026 0

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

115 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Ambroxol for women at risk of preterm birth for preventing neonatal respiratory distress syndrome.
Gonzalez Garay AG, Reveiz L, Velasco Hidalgo L, Solis Galicia C. Gonzalez Garay AG, et al. Cochrane Database Syst Rev. 2014 Oct 31;2014(10):CD009708. doi: 10.1002/14651858.CD009708.pub2. Cochrane Database Syst Rev. 2014. PMID: 25361381 Free PMC article.
Nor did we identify any trials comparing ambroxol combined with corticosteroid versus corticosteroid alone, or placebo/no treatment. ...However, three of the included studies did not report on this review's outcomes of interest. We carried out two main comparisons: ambr
Nor did we identify any trials comparing ambroxol combined with corticosteroid versus corticosteroid alone, or placebo/no treatment. …
Efficacy of Ambroxol lozenges for pharyngitis: a meta-analysis.
Chenot JF, Weber P, Friede T. Chenot JF, et al. BMC Fam Pract. 2014 Mar 13;15:45. doi: 10.1186/1471-2296-15-45. BMC Fam Pract. 2014. PMID: 24621446 Free PMC article.
BACKGROUND: Ambroxol has a local anaesthetic action and is marketed for pain relief for sore throat. ...Ambroxol is a safe option for individual patients with mainly local symptoms asking for treatment....
BACKGROUND: Ambroxol has a local anaesthetic action and is marketed for pain relief for sore throat. ...Ambroxol is a safe opt …
The application of ambroxol hydrochloride combined with fiberoptic bronchoscopy in elderly patients with severe pneumonia: A meta-analysis and systematic review.
Tang H, Yuan Z, Li J, Wang Q, Fan W. Tang H, et al. Medicine (Baltimore). 2022 Jan 28;101(4):e28535. doi: 10.1097/MD.0000000000028535. Medicine (Baltimore). 2022. PMID: 35089191 Free PMC article.
BACKGROUND: The role of ambroxol hydrochloride combined with fiberoptic bronchoscopy in elderly patients with severe pneumonia remains unclear, we aimed to analyze this issue to provide evidences into the management of clinical pneumonia. METHODS: We searched PubMed et al …
BACKGROUND: The role of ambroxol hydrochloride combined with fiberoptic bronchoscopy in elderly patients with severe pneumonia remain …
[Ambroxol for the prevention of respiratory distress syndrome in preterm infants: a meta analysis].
Zhang ZQ, Huang XM, Lu H. Zhang ZQ, et al. Zhongguo Dang Dai Er Ke Za Zhi. 2010 Nov;12(11):858-63. Zhongguo Dang Dai Er Ke Za Zhi. 2010. PMID: 21083978 Free article. Chinese.
OBJECTIVE: To evaluate the efficacy and safety of ambroxol in the prevention of respiratory distress syndrome (RDS) in preterm infants. METHODS: Electronic searches were performed in the Cochrane Library, PubMED, EMBASE, Chinese CBM, Chinese VIP Database, Chinese Wanfang D …
OBJECTIVE: To evaluate the efficacy and safety of ambroxol in the prevention of respiratory distress syndrome (RDS) in preterm infant …
The combination of astragalus injection and ambroxol hydrochloride in the adjuvant treatment of COPD: a systematic review and meta-analysis.
Zhou Z, Yang L, Hu C, Gao R, Zhang X, Shen T. Zhou Z, et al. Sci Rep. 2023 Dec 12;13(1):22077. doi: 10.1038/s41598-023-49421-6. Sci Rep. 2023. PMID: 38087032 Free PMC article.
An adjunctive therapy in COPD includes the simultaneous administration of astragalus injection and ambroxol hydrochloride. Despite its widespread use, the effectiveness of this combined approach in COPD treatment has not been systematically evaluated. ...The combination of …
An adjunctive therapy in COPD includes the simultaneous administration of astragalus injection and ambroxol hydrochloride. Despite it …
Effects of N-Acetylcysteine combined with Ambroxol Hydrochloride on clinical symptoms, CRP, and PCT in children with pneumonia.
Xue A, Zhang H, Song S, Yu X. Xue A, et al. Clinics (Sao Paulo). 2024 Aug 28;79:100476. doi: 10.1016/j.clinsp.2024.100476. eCollection 2024. Clinics (Sao Paulo). 2024. PMID: 39208656 Free PMC article. Clinical Trial.
OBJECTIVE: This study investigated the effects of N-Acetylcysteine (NAC) combined with Ambroxol Hydrochloride (AH) on clinical symptoms, C-Reactive Protein (CRP), and Procalcitonin (PCT) levels in children with pneumonia. ...
OBJECTIVE: This study investigated the effects of N-Acetylcysteine (NAC) combined with Ambroxol Hydrochloride (AH) on clinical sympto …
Meta-analysis of high doses of ambroxol treatment for acute lung injury/acute respiratory distress syndrome based on randomized controlled trials.
Wu X, Li S, Zhang J, Zhang Y, Han L, Deng Q, Wan X. Wu X, et al. J Clin Pharmacol. 2014 Nov;54(11):1199-206. doi: 10.1002/jcph.389. Epub 2014 Sep 7. J Clin Pharmacol. 2014. PMID: 25174313
This study seeks to evaluate the potential benefits of high doses of ambroxol treatment for acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) by conducting a meta-analysis based on randomized controlled trials (RCTs). ...The findings suggest that treatment …
This study seeks to evaluate the potential benefits of high doses of ambroxol treatment for acute lung injury (ALI)/acute respiratory …
LC-MS/MS-Based Determination of Ambroxol in Human Plasma and Cerebrospinal Fluid: Validation and Applicability in a Phase II Study on GBA-Associated Parkinson's Disease Patients.
Franco V, Palmisani M, Colucci F, De Micco R, Aloisio S, Cazzaniga F, Cerri S, Crema F, Dattrino F, Garavaglia B, Gastaldi M, Mitrotti P, Moda F, Rota P, Stiuso R, Tassorelli C, Eleopra R, Tessitore A, Valente EM, Avenali M, Cilia R. Franco V, et al. Int J Mol Sci. 2025 Jun 25;26(13):6094. doi: 10.3390/ijms26136094. Int J Mol Sci. 2025. PMID: 40649871 Free PMC article. Clinical Trial.
This study aimed to develop a method to quantify ambroxol levels in human plasma and cerebrospinal fluid (CSF) using liquid chromatography-tandem mass spectrometry (LC-MS/MS). Ambroxol was determined by online solid-phase extraction (SPE), coupled with LC-MS/MS, by …
This study aimed to develop a method to quantify ambroxol levels in human plasma and cerebrospinal fluid (CSF) using liquid chromatog …
Prevention of respiratory distress syndrome in preterm infants by antenatal ambroxol: a meta-analysis of randomized controlled trials.
Zhang ZQ, Wu QQ, Huang XM, Lu H. Zhang ZQ, et al. Am J Perinatol. 2013 Aug;30(7):529-36. doi: 10.1055/s-0032-1329684. Epub 2012 Dec 10. Am J Perinatol. 2013. PMID: 23229957
OBJECTIVE: To evaluate the efficacy and safety of antenatal ambroxol as a preventive therapeutic of respiratory distress syndrome (RDS) in preterm infants. ...The ambroxol-treated group had lower risk of neonatal infection than the corticosteroid-treated group (RR = …
OBJECTIVE: To evaluate the efficacy and safety of antenatal ambroxol as a preventive therapeutic of respiratory distress syndrome (RD …
Efficacy and safety of inhaled ambroxol hydrochloride solution in patients with lower respiratory tract infectious diseases: a randomized, double-blind, placebo-controlled, multicentre clinical trial.
Wu D, Fu X, Jin F, Li H, Qin Z, Wang H, Yue H, Zhang J, Cao Z. Wu D, et al. BMC Infect Dis. 2025 Jul 1;25(1):830. doi: 10.1186/s12879-025-11194-w. BMC Infect Dis. 2025. PMID: 40596900 Free PMC article. Clinical Trial.
BACKGROUND: Ambroxol is a widely used mucoactive agent, but the efficacy of inhaled ambroxol in patients with lower respiratory tract infectious (LRTI) disease is poorly understood. This trial aimed to compare the efficacy and safety of inhaled ambroxol with …
BACKGROUND: Ambroxol is a widely used mucoactive agent, but the efficacy of inhaled ambroxol in patients with lower respirator …
115 results