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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1966 2
1968 1
1972 2
1973 1
1975 4
1976 2
1978 1
1982 1
1983 2
1984 3
1985 3
1986 5
1987 5
1988 3
1989 2
1990 3
1991 5
1992 4
1993 5
1994 4
1995 3
1996 4
1997 7
1998 7
1999 5
2000 5
2001 7
2002 2
2003 6
2004 5
2005 6
2006 6
2007 5
2008 7
2009 7
2010 2
2011 5
2012 7
2013 10
2014 7
2015 9
2016 4
2017 6
2018 8
2019 13
2020 3
2021 4
2022 8
2023 6
2024 3
2025 0

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222 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Epsilon-aminocaproic acid versus tranexamic acid in total knee arthroplasty: a meta-analysis study.
Riaz O, Aqil A, Asmar S, Vanker R, Hahnel J, Brew C, Grogan R, Radcliffe G. Riaz O, et al. J Orthop Traumatol. 2019 Jul 18;20(1):28. doi: 10.1186/s10195-019-0534-2. J Orthop Traumatol. 2019. PMID: 31321578 Free PMC article. Review.
The objective of this meta-analysis is to determine which of tranexamic acid (TXA) and epsilon-aminocaproic acid (EACA) is more effective for reducing peri-operative blood loss, and lessening the need for blood transfusion following knee arthroplasty surgery. …
The objective of this meta-analysis is to determine which of tranexamic acid (TXA) and epsilon-aminocaproic acid (EACA) …
Efficacy of aminocaproic acid in the control of bleeding after total knee and hip arthroplasty: A systematic review and meta-analysis.
Li Y, Wang J. Li Y, et al. Medicine (Baltimore). 2019 Mar;98(9):e14764. doi: 10.1097/MD.0000000000014764. Medicine (Baltimore). 2019. PMID: 30817636 Free PMC article.
BACKGROUND: To assess the effectiveness and safety of intravenous aminocaproic acid for blood management after total knee and hip arthroplasty. METHODS: Electronic databases: PubMed (1950.1-2018.8), EMBASE (1974.1-2018.8), the Cochrane Central Register of Controlled …
BACKGROUND: To assess the effectiveness and safety of intravenous aminocaproic acid for blood management after total knee and …
The Optimal Dose, Efficacy and Safety of Tranexamic Acid and Epsilon-Aminocaproic Acid to Reduce Bleeding in TKA: A Systematic Review and Bayesian Network Meta-analysis.
Zheng C, Ma J, Xu J, Li M, Wu L, Wu Y, Liu Y, Shen B. Zheng C, et al. Orthop Surg. 2023 Apr;15(4):930-946. doi: 10.1111/os.13678. Epub 2023 Mar 6. Orthop Surg. 2023. PMID: 36878889 Free PMC article.
OBJECTIVE: The optimal dose and efficacy of tranexamic acid (TXA) and epsilon-aminocaproic acid (EACA) in total knee arthroplasty (TKA) were under controversial, and we aimed to make comparisons between different doses of TXA and EACA in intravenous (IV) or i …
OBJECTIVE: The optimal dose and efficacy of tranexamic acid (TXA) and epsilon-aminocaproic acid (EACA) in total knee ar …
The optimal regimen, efficacy and safety of tranexamic acid and aminocaproic acid to reduce bleeding for patients after total hip arthroplasty: A systematic review and Bayesian network meta-analysis.
Zheng C, Ma J, Xu J, Wu L, Wu Y, Liu Y, Shen B. Zheng C, et al. Thromb Res. 2023 Jan;221:120-129. doi: 10.1016/j.thromres.2022.11.010. Epub 2022 Dec 5. Thromb Res. 2023. PMID: 36527742
OBJECTIVES: We aimed to evaluate the optimal regimen, efficacy and safety of tranexamic acid (TXA) and aminocaproic acid (EACA) for patients after total hip arthroplasty (THA). ...
OBJECTIVES: We aimed to evaluate the optimal regimen, efficacy and safety of tranexamic acid (TXA) and aminocaproic acid
Tranexamic acid versus aminocaproic acid for blood management after total knee and total hip arthroplasty: A systematic review and meta-analysis.
Liu Q, Geng P, Shi L, Wang Q, Wang P. Liu Q, et al. Int J Surg. 2018 Jun;54(Pt A):105-112. doi: 10.1016/j.ijsu.2018.04.042. Epub 2018 May 1. Int J Surg. 2018. PMID: 29723672 Free article. Review.
OBJECTIVE: To compare the efficacy and safety of tranexamic acid and aminocaproic acid for reducing blood loss and transfusion requirements after total knee and total hip arthroplasty. ...
OBJECTIVE: To compare the efficacy and safety of tranexamic acid and aminocaproic acid for reducing blood loss and tran …
Tranexamic Acid versus Epsilon-Aminocaproic Acid in Total Knee Arthroplasty: A Meta-Analysis.
Li Z, Sun X, Li W, Zhang M. Li Z, et al. J Healthc Eng. 2021 Nov 3;2021:1758066. doi: 10.1155/2021/1758066. eCollection 2021. J Healthc Eng. 2021. Retraction in: J Healthc Eng. 2023 Nov 1;2023:9894509. doi: 10.1155/2023/9894509 PMID: 34777729 Free PMC article. Retracted.
OBJECTIVE: At present, the effect of tranexamic acid (TXA) and epsilon-aminocaproic acid (EACA) on total knee arthroplasty (TKA) remains controversial. ...
OBJECTIVE: At present, the effect of tranexamic acid (TXA) and epsilon-aminocaproic acid (EACA) on total knee arthropla …
The Efficacy and Safety of Epsilon-Aminocaproic Acid for Blood Loss and Transfusions in Spinal Deformity Surgery: A Meta-Analysis.
Chen R, Xiang Z, Gong M. Chen R, et al. World Neurosurg. 2019 Aug;128:579-586.e1. doi: 10.1016/j.wneu.2019.03.186. Epub 2019 Mar 26. World Neurosurg. 2019. PMID: 30926553 Review.
OBJECTIVE: To assess the efficacy and safety of epsilon-aminocaproic acid (EACA) in reducing the blood loss and transfusion volume during open spinal deformity surgery. ...
OBJECTIVE: To assess the efficacy and safety of epsilon-aminocaproic acid (EACA) in reducing the blood loss and transfusion vo …
The effect of aprotinin, tranexamic acid, and aminocaproic acid on blood loss and use of blood products in major pediatric surgery: a meta-analysis.
Schouten ES, van de Pol AC, Schouten AN, Turner NM, Jansen NJ, Bollen CW. Schouten ES, et al. Pediatr Crit Care Med. 2009 Mar;10(2):182-90. doi: 10.1097/PCC.0b013e3181956d61. Pediatr Crit Care Med. 2009. PMID: 19188875 Review.
Aprotinin has been associated with severe side effects in adults, and tranexamic acid and aminocaproic acid have been found to be safer alternatives in adults. This systematic review addresses the question of whether tranexamic acid and aminocaproic
Aprotinin has been associated with severe side effects in adults, and tranexamic acid and aminocaproic acid have been f …
The effectiveness and safety of aminocaproic acid for reducing blood loss in total knee and hip arthroplasty: A meta-analysis.
Dong Q, Zhang Y, Sun X, Hu F. Dong Q, et al. Int J Surg. 2018 Apr;52:156-163. doi: 10.1016/j.ijsu.2018.02.035. Epub 2018 Feb 20. Int J Surg. 2018. PMID: 29471157 Free article. Review.
Our study indicated that intravenous aminocaproic acid was associated with a significantly reduction in total blood loss, hemoglobin drop and need for transfusion. ...Further studies should focus on the comparison of aminocaproic acid and TXA in arthro …
Our study indicated that intravenous aminocaproic acid was associated with a significantly reduction in total blood loss, hemo …
The Efficacy and Safety of Epsilon-Aminocaproic Acid for Perioperative Blood Management in Spinal Fusion Surgery: A Systematic Review and Meta-Analysis.
Li S, Xing F, Cen Y, Zhang Z. Li S, et al. World Neurosurg. 2021 Dec;156:12-21. doi: 10.1016/j.wneu.2021.08.113. Epub 2021 Aug 31. World Neurosurg. 2021. PMID: 34478888
Recent clinical studies have focused on the perioperative administration of epsilon-aminocaproic acid (EACA) in spinal fusion surgery. The aim of this review was to evaluate the efficacy and safety of EACA in spinal fusion surgery. ...
Recent clinical studies have focused on the perioperative administration of epsilon-aminocaproic acid (EACA) in spinal fusion …
222 results