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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1948 3
1949 3
1950 4
1951 5
1952 2
1953 5
1954 2
1955 2
1956 2
1957 5
1960 1
1963 1
1966 1
1967 1
1969 1
1972 1
1973 1
1974 2
1976 5
1977 6
1978 5
1979 4
1980 5
1981 6
1982 13
1983 16
1984 16
1985 12
1986 14
1987 12
1988 8
1989 12
1990 4
1991 7
1992 12
1993 5
1994 4
1995 11
1996 16
1997 15
1998 5
1999 16
2000 17
2001 14
2002 11
2003 10
2004 14
2005 16
2006 10
2007 22
2008 11
2009 14
2010 19
2011 12
2012 19
2013 16
2014 14
2015 13
2016 22
2017 19
2018 28
2019 20
2020 27
2021 19
2022 22
2023 11

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615 results

Results by year

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Page 1
Doxorubicin chemotherapy-induced "chemo-brain": Meta-analysis.
Eide S, Feng ZP. Eide S, et al. Eur J Pharmacol. 2020 Aug 15;881:173078. doi: 10.1016/j.ejphar.2020.173078. Epub 2020 Jun 5. Eur J Pharmacol. 2020. PMID: 32505665 Review.
Although cognitive impairment is commonly recorded in patients after chemotherapy, the occurrence of doxorubicin-induced "chemo-brain" is debated, as doxorubicin cannot cross the blood-brain barrier. However, the potential of indirect doxorubicin neurotoxicity remains, pro …
Although cognitive impairment is commonly recorded in patients after chemotherapy, the occurrence of doxorubicin-induced "chemo-brain" is de …
Aminoglycoside neurotoxicity involves NMDA receptor activation.
Segal JA, Harris BD, Kustova Y, Basile A, Skolnick P. Segal JA, et al. Brain Res. 1999 Jan 9;815(2):270-7. doi: 10.1016/s0006-8993(98)01123-8. Brain Res. 1999. PMID: 9878779
If this hypothesis is correct, then these antibiotics should also injure neurons within the brain. Because aminoglycosides do not readily penetrate the blood brain barrier, we examined the effects of the aminoglycoside neomycin following intrastriatal injection. ... …
If this hypothesis is correct, then these antibiotics should also injure neurons within the brain. Because aminoglycosides do not rea …
Neurotoxicity of metrizamide.
Ekholm S, Fischer H. Ekholm S, et al. Arch Neurol. 1985 Jan;42(1):24-5. doi: 10.1001/archneur.1985.04060010030010. Arch Neurol. 1985. PMID: 3966880 No abstract available.
Neurotoxicity with antimicrobials in the elderly: a review.
Mattappalil A, Mergenhagen KA. Mattappalil A, et al. Clin Ther. 2014 Nov 1;36(11):1489-1511.e4. doi: 10.1016/j.clinthera.2014.09.020. Epub 2014 Nov 4. Clin Ther. 2014. PMID: 25450476 Review.
A higher risk of developing various symptoms of neurotoxicity was found in the elderly with use of piperacillin and tazobactam, cephalosporins, carbapenems, aminoglycosides, trimethoprim and sulfamethoxazole, nitrofurantoin, linezolid, and possibly the fluoroquinolo …
A higher risk of developing various symptoms of neurotoxicity was found in the elderly with use of piperacillin and tazobactam, cepha …
Aminoglycoside-Related Nephrotoxicity and Ototoxicity in Clinical Practice: A Review of Pathophysiological Mechanism and Treatment Options.
Le TA, Hiba T, Chaudhari D, Preston AN, Palowsky ZR, Ahmadzadeh S, Shekoohi S, Cornett EM, Kaye AD. Le TA, et al. Adv Ther. 2023 Apr;40(4):1357-1365. doi: 10.1007/s12325-023-02436-x. Epub 2023 Feb 4. Adv Ther. 2023. PMID: 36738370 Review.
Aminoglycosides are a class of medications used to treat certain bacterial infections, specifically gram-negative aerobes. ...The most prevalent side effects of aminoglycosides are nephrotoxicity and ototoxicity. Aminoglycoside-induced nephrotoxicity is conce …
Aminoglycosides are a class of medications used to treat certain bacterial infections, specifically gram-negative aerobes. ...The mos …
Neurotoxicity of dihydrostreptomycin.
SHANE SJ, LAURIE JH. SHANE SJ, et al. Can Med Assoc J. 1950 Sep;63(3):277-9. Can Med Assoc J. 1950. PMID: 15434767 Free PMC article. No abstract available.
Altretamine.
Hansen LA, Hughes TE. Hansen LA, et al. DICP. 1991 Feb;25(2):146-52. doi: 10.1177/106002809102500209. DICP. 1991. PMID: 1905441 Review.
Dose-limiting toxicities include gastrointestinal (nausea, vomiting, anorexia), hematologic, and neurotoxic (peripheral neurotoxicity). The therapeutic role of altretamine is limited because of a toxicity profile similar to that of cisplatin, one of the more active …
Dose-limiting toxicities include gastrointestinal (nausea, vomiting, anorexia), hematologic, and neurotoxic (peripheral neurotoxic …
Vancomycin.
Geraci JE. Geraci JE. Mayo Clin Proc. 1977 Oct;52(10):631-4. Mayo Clin Proc. 1977. PMID: 909314
Streptococcal endocarditis in patients intolerant to penicillin G; in enterococcal infections, it is used with an associated aminoglycoside. Vancomycin is not used alone in enterococcal endocarditis. ...Vancomycin is relatively nontoxic; the predominant toxic response is …
Streptococcal endocarditis in patients intolerant to penicillin G; in enterococcal infections, it is used with an associated aminoglycosi …
Ertapenem Neurotoxicity in Hemodialysis Patients-Safe and Effective Dosing Is Still Needed: A Retrospective Study and Literature Review.
El Nekidy WS, Elrefaei H, St John TJL, Attallah NM, Kablaoui F, Nusair A, Piechowski-Jozwiak B, Phillips J, Ghazi IM. El Nekidy WS, et al. Ann Pharmacother. 2021 Jan;55(1):52-58. doi: 10.1177/1060028020938059. Epub 2020 Jul 3. Ann Pharmacother. 2021. PMID: 32618479 Review.
Patients' demographics, comorbidities, concomitant drugs (known to induce neurotoxicity), and seizure history were collected. RESULTS: A total of 99 eligible patients were identified; 10 of them (10%) developed neurotoxicity. ...The following were the significant pr …
Patients' demographics, comorbidities, concomitant drugs (known to induce neurotoxicity), and seizure history were collected. RESULTS …
The neurotoxicity of antibacterial agents.
Snavely SR, Hodges GR. Snavely SR, et al. Ann Intern Med. 1984 Jul;101(1):92-104. doi: 10.7326/0003-4819-101-1-92. Ann Intern Med. 1984. PMID: 6329054 Review.
Commonly used antibacterial agents may be associated with various neurotoxic reactions. Central nervous system toxicities include seizure disorders, encephalopathy, bulging fontanelles, and neuropsychiatric symptoms. These abnormalities have been associated with the use of …
Commonly used antibacterial agents may be associated with various neurotoxic reactions. Central nervous system toxicities include sei …
615 results