Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1984 1
1988 1
1995 2
1996 1
1999 4
2000 7
2001 5
2002 7
2003 10
2004 10
2005 12
2006 18
2007 22
2008 19
2009 23
2010 25
2011 23
2012 27
2013 27
2014 35
2015 26
2016 34
2017 27
2018 31
2019 33
2020 30
2021 33
2022 25
2023 20
2024 19
2025 4

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

472 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma: a randomised controlled multicentre phase III trial.
Stummer W, Pichlmeier U, Meinel T, Wiestler OD, Zanella F, Reulen HJ; ALA-Glioma Study Group. Stummer W, et al. Lancet Oncol. 2006 May;7(5):392-401. doi: 10.1016/S1470-2045(06)70665-9. Lancet Oncol. 2006. PMID: 16648043 Clinical Trial.
We aimed to assess the effect of fluorescence-guided resection with 5-aminolevulinic acid on surgical radicality, progression-free survival, overall survival, and morbidity. ...INTERPRETATION: Tumour fluorescence derived from 5-aminolevulinic acid enab …
We aimed to assess the effect of fluorescence-guided resection with 5-aminolevulinic acid on surgical radicality, progression- …
5-Aminolevulinic acid photodynamic therapy versus minocycline for moderate-to-severe rosacea: A single-center, randomized, evaluator-blind controlled study.
Yang J, Liu X, Cao Y, Wang P, Zhang H, Chen Q, Yang Y, Zeng Q, Zhang L, Wang X. Yang J, et al. J Am Acad Dermatol. 2023 Oct;89(4):711-718. doi: 10.1016/j.jaad.2023.06.027. Epub 2023 Jun 24. J Am Acad Dermatol. 2023. PMID: 37356626 Clinical Trial.
BACKGROUND: 5-Aminolevulinic acid photodynamic therapy (ALA-PDT) showed potential to treat rosacea according to recent studies; however, a lack of clinical evidence and unclear adverse effects limit its use. ...
BACKGROUND: 5-Aminolevulinic acid photodynamic therapy (ALA-PDT) showed potential to treat rosacea according to recent studies …
Modified red light 5-aminolevulinic acid photodynamic therapy versus low-dose isotretinoin therapy for moderate to severe acne vulgaris: A prospective, randomized, multicenter study.
Zhang L, Yang Y, Wang B, Zhao Y, Wang P, Liu J, Yang J, Wu Y, Lv T, Wei Z, Liu X, Wang R, Wong H, Ju Q, Shi L, Wang X. Zhang L, et al. J Am Acad Dermatol. 2023 Dec;89(6):1141-1148. doi: 10.1016/j.jaad.2023.07.1023. Epub 2023 Aug 7. J Am Acad Dermatol. 2023. PMID: 37558093 Clinical Trial.
BACKGROUND: Modified 5-aminolevulinic acid photodynamic therapy (M-PDT) and isotretinoin (ISO) are effective treatments for moderate to severe acne vulgaris. ...
BACKGROUND: Modified 5-aminolevulinic acid photodynamic therapy (M-PDT) and isotretinoin (ISO) are effective treatments for mo …
Intraoperative Fluorophores: An Update on 5-Aminolevulinic Acid and Sodium Fluorescein in Resection of Tumors of the Central Nervous System and Metastatic Lesions-A Systematic Review and Meta-Analysis.
Shah S, Ivey N, Matur A, Andaluz N. Shah S, et al. Tomography. 2023 Aug 22;9(5):1551-1567. doi: 10.3390/tomography9050124. Tomography. 2023. PMID: 37736977 Free PMC article. Review.
One area of recent interest has been the use of intraoperative fluorophores for tumor visualization such as 5-aminolevulinic acid (5-ala) and sodium fluorescein. We performed a systematic review and meta-analysis on the utility of fluorophore administration and EOR …
One area of recent interest has been the use of intraoperative fluorophores for tumor visualization such as 5-aminolevulinic acid
5-aminolevulinic acid-based photodynamic therapy for the treatment of condylomata acuminata in Chinese patients: a meta-analysis.
Ying Z, Li X, Dang H. Ying Z, et al. Photodermatol Photoimmunol Photomed. 2013 Jun;29(3):149-59. doi: 10.1111/phpp.12043. Photodermatol Photoimmunol Photomed. 2013. PMID: 23651275 Review.
OBJECTIVE: This meta-analysis was designed to assess the efficacy of topical 5-aminolaevulinic acid (ALA) photodynamic therapy (PDT) in Chinese patients with condylomata acuminata (CA). ...
OBJECTIVE: This meta-analysis was designed to assess the efficacy of topical 5-aminolaevulinic acid (ALA) photodynamic therapy (PDT) …
Sodium fluorescein and 5-aminolevulinic acid fluorescence- guided biopsy in brain lesions: a systematic review and meta-analysis.
Gomes FC, Ferreira MY, Larcipretti ALL, Freitas BCB, Andreão FF, Turpin J, Bertani R, Singha S, Polverini AD, Ferreira C, Dellaretti M, D'Amico RS. Gomes FC, et al. J Neurooncol. 2024 Oct;170(1):11-29. doi: 10.1007/s11060-024-04779-z. Epub 2024 Aug 10. J Neurooncol. 2024. PMID: 39126591
Fluorescence-based agents such as 5-aminolevulinic acid (5-ALA) and fluorescein sodium (NaFl) can enhance diagnostic accuracy and safety, improving the visualization of lesional tissues. ...
Fluorescence-based agents such as 5-aminolevulinic acid (5-ALA) and fluorescein sodium (NaFl) can enhance diagnostic accuracy …
Repeated 5-aminolevulinic Acid Instillations During Follow-up in Non-muscle-invasive Bladder Cancer: A Randomized Study.
Kelloniemi E, Järvinen R, Hellström P, Rintala E, Aaltomaa S, Isotalo T, Innos K, Kaasinen E. Kelloniemi E, et al. In Vivo. 2021 May-Jun;35(3):1561-1568. doi: 10.21873/invivo.12411. In Vivo. 2021. PMID: 33910836 Free PMC article. Clinical Trial.
BACKGROUND/AIM: Non-muscle invasive bladder carcinoma (NMIBC) is highly recurrent. We studied if 5-aminolevulinic acid (5-ALA) instillations before transurethral resection of bladder tumours (TURBT) and cystoscopy extend the time to recurrence during follow-up with …
BACKGROUND/AIM: Non-muscle invasive bladder carcinoma (NMIBC) is highly recurrent. We studied if 5-aminolevulinic acid (5-ALA) …
Efficacy of aminolevulinic acid 20 % solution photodynamic therapy in the treatment of actinic keratoses on the upper extremities: A post hoc analysis of a phase 3, randomized, vehicle-controlled trial.
Berman B, Bhatia N, Piacquadio D, Houlihan A, Davidson D, Siegel D. Berman B, et al. Photodiagnosis Photodyn Ther. 2020 Dec;32:102013. doi: 10.1016/j.pdpdt.2020.102013. Epub 2020 Sep 15. Photodiagnosis Photodyn Ther. 2020. PMID: 32947028 Free article. Clinical Trial.
BACKGROUND: Photodynamic therapy with 5-aminolevulinic acid is indicated for targeted treatment of actinic keratoses on the face, scalp, and upper extremities. ...Aminolevulinic acid/photodynamic therapy was well tolerated with adverse events consisten …
BACKGROUND: Photodynamic therapy with 5-aminolevulinic acid is indicated for targeted treatment of actinic keratoses on the fa …
Fluorescence image-guided neurosurgery.
Kaneko S, Eljamel MS. Kaneko S, et al. Future Oncol. 2017 Nov;13(26):2341-2348. doi: 10.2217/fon-2017-0194. Epub 2017 Nov 10. Future Oncol. 2017. PMID: 29121788 Review.
A critical literature review revealed fluorescence improved the GTR of HGG from 36% using standard surgery to 74.5 and 84.4% using aminolevulinic acid (ALA) or fluorescein (FLCN), respectively. The differences between ALA-fluorescence image-guided neurosurgery (FIGS …
A critical literature review revealed fluorescence improved the GTR of HGG from 36% using standard surgery to 74.5 and 84.4% using aminol
The role of 5-aminolevulinic acid in enhancing surgery for high-grade glioma, its current boundaries, and future perspectives: A systematic review.
Mansouri A, Mansouri S, Hachem LD, Klironomos G, Vogelbaum MA, Bernstein M, Zadeh G. Mansouri A, et al. Cancer. 2016 Aug 15;122(16):2469-78. doi: 10.1002/cncr.30088. Epub 2016 May 16. Cancer. 2016. PMID: 27183272 Free article. Review.
5-Aminolevulinic acid (5-ALA) has been approved as an intraoperative adjunct in glioma surgery in Europe, but not North America. ...
5-Aminolevulinic acid (5-ALA) has been approved as an intraoperative adjunct in glioma surgery in Europe, but not North Americ …
472 results