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Year Number of Results
1968 1
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1980 1
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1986 8
1987 5
1988 3
1989 6
1990 10
1991 8
1992 15
1993 20
1994 19
1995 13
1996 14
1997 18
1998 11
1999 27
2000 29
2001 15
2002 30
2003 39
2004 32
2005 21
2006 34
2007 31
2008 33
2009 27
2010 27
2011 29
2012 23
2013 23
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2025 5

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757 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Amiodarone, Lidocaine, or Placebo in Out-of-Hospital Cardiac Arrest.
Kudenchuk PJ, Brown SP, Daya M, Rea T, Nichol G, Morrison LJ, Leroux B, Vaillancourt C, Wittwer L, Callaway CW, Christenson J, Egan D, Ornato JP, Weisfeldt ML, Stiell IG, Idris AH, Aufderheide TP, Dunford JV, Colella MR, Vilke GM, Brienza AM, Desvigne-Nickens P, Gray PC, Gray R, Seals N, Straight R, Dorian P; Resuscitation Outcomes Consortium Investigators. Kudenchuk PJ, et al. N Engl J Med. 2016 May 5;374(18):1711-22. doi: 10.1056/NEJMoa1514204. Epub 2016 Apr 4. N Engl J Med. 2016. PMID: 27043165 Free article. Clinical Trial.
RESULTS: In the per-protocol population, 3026 patients were randomly assigned to amiodarone (974), lidocaine (993), or placebo (1059); of those, 24.4%, 23.7%, and 21.0%, respectively, survived to hospital discharge. The difference in survival rate for amiodarone ver …
RESULTS: In the per-protocol population, 3026 patients were randomly assigned to amiodarone (974), lidocaine (993), or placebo (1059) …
Randomized comparison of intravenous procainamide vs. intravenous amiodarone for the acute treatment of tolerated wide QRS tachycardia: the PROCAMIO study.
Ortiz M, Martín A, Arribas F, Coll-Vinent B, Del Arco C, Peinado R, Almendral J; PROCAMIO Study Investigators. Ortiz M, et al. Eur Heart J. 2017 May 1;38(17):1329-1335. doi: 10.1093/eurheartj/ehw230. Eur Heart J. 2017. PMID: 27354046 Free PMC article. Clinical Trial.
AIMS: Intravenous procainamide and amiodarone are drugs of choice for well-tolerated ventricular tachycardia. However, the choice between them, even according to Guidelines, is unclear. ...Tachycardia terminated within 40 min in 22 (67%) procainamide and 11 (38%) amioda
AIMS: Intravenous procainamide and amiodarone are drugs of choice for well-tolerated ventricular tachycardia. However, the choice bet …
Amiodarone or an implantable cardioverter-defibrillator for congestive heart failure.
Bardy GH, Lee KL, Mark DB, Poole JE, Packer DL, Boineau R, Domanski M, Troutman C, Anderson J, Johnson G, McNulty SE, Clapp-Channing N, Davidson-Ray LD, Fraulo ES, Fishbein DP, Luceri RM, Ip JH; Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT) Investigators. Bardy GH, et al. N Engl J Med. 2005 Jan 20;352(3):225-37. doi: 10.1056/NEJMoa043399. N Engl J Med. 2005. PMID: 15659722 Free article. Clinical Trial.
Placebo and amiodarone were administered in a double-blind fashion. The primary end point was death from any cause. ...CONCLUSIONS: In patients with NYHA class II or III CHF and LVEF of 35 percent or less, amiodarone has no favorable effect on survival, whereas sing …
Placebo and amiodarone were administered in a double-blind fashion. The primary end point was death from any cause. ...CONCLUSIONS: I …
Propafenone versus amiodarone for supraventricular arrhythmias in septic shock: a randomised controlled trial.
Balik M, Maly M, Brozek T, Rulisek J, Porizka M, Sachl R, Otahal M, Brestovansky P, Svobodova E, Flaksa M, Stach Z, Horejsek J, Volny L, Jurisinova I, Novotny A, Trachta P, Kunstyr J, Kopecky P, Tencer T, Pazout J, Belohlavek J, Duska F, Krajcova A, Waldauf P. Balik M, et al. Intensive Care Med. 2023 Nov;49(11):1283-1292. doi: 10.1007/s00134-023-07208-3. Epub 2023 Sep 12. Intensive Care Med. 2023. PMID: 37698594 Clinical Trial.
After 24 h, 77 (72.8%) and 71 (67.3%) were in sinus rhythm (p = 0.4), restored after a median of 3.7 h (95% CI 2.3-6.8) and 7.3 h (95% CI 5-11), p = 0.02, with propafenone and amiodarone, respectively. The arrhythmia recurred in 54 (52%) patients treated with propafenone a …
After 24 h, 77 (72.8%) and 71 (67.3%) were in sinus rhythm (p = 0.4), restored after a median of 3.7 h (95% CI 2.3-6.8) and 7.3 h (95% CI 5- …
Amiodarone and/or lidocaine for cardiac arrest: A Bayesian network meta-analysis.
Zhao H, Fan K, Feng G. Zhao H, et al. Am J Emerg Med. 2020 Oct;38(10):2185-2193. doi: 10.1016/j.ajem.2020.06.074. Epub 2020 Jul 5. Am J Emerg Med. 2020. PMID: 33071078
In terms of survival to hospital discharge, amiodarone (OR 1.18, 95% CrI 1.03-1.35) and lidocaine (OR 1.22, 95% CrI 1.06-1.41) were more effective than placebo. Amiodarone (OR 1.20, 95% CrI 1.02-1.41) was significantly better than placebo in favorable neurological o …
In terms of survival to hospital discharge, amiodarone (OR 1.18, 95% CrI 1.03-1.35) and lidocaine (OR 1.22, 95% CrI 1.06-1.41) were m …
Prevalence of amiodarone-induced hypothyroidism; A systematic review and meta-analysis.
Mohammadi K, Shafie D, Vakhshoori M, Bondariyan N, Rezvanian H, Heidarpour M. Mohammadi K, et al. Trends Cardiovasc Med. 2023 May;33(4):252-262. doi: 10.1016/j.tcm.2022.01.001. Epub 2022 Jan 11. Trends Cardiovasc Med. 2023. PMID: 35026394 Review.
Amiodarone is a common anti-arrhythmic agent mostly used to treat and prevent different kinds of arrhythmia with several considerable side effects, most commonly on the thyroid gland. We aimed to assess the frequency of hypothyroidism among chronic amiodarone users.
Amiodarone is a common anti-arrhythmic agent mostly used to treat and prevent different kinds of arrhythmia with several considerable
Ablation Versus Amiodarone for Treatment of Persistent Atrial Fibrillation in Patients With Congestive Heart Failure and an Implanted Device: Results From the AATAC Multicenter Randomized Trial.
Di Biase L, Mohanty P, Mohanty S, Santangeli P, Trivedi C, Lakkireddy D, Reddy M, Jais P, Themistoclakis S, Dello Russo A, Casella M, Pelargonio G, Narducci ML, Schweikert R, Neuzil P, Sanchez J, Horton R, Beheiry S, Hongo R, Hao S, Rossillo A, Forleo G, Tondo C, Burkhardt JD, Haissaguerre M, Natale A. Di Biase L, et al. Circulation. 2016 Apr 26;133(17):1637-44. doi: 10.1161/CIRCULATIONAHA.115.019406. Epub 2016 Mar 30. Circulation. 2016. PMID: 27029350 Free article. Clinical Trial.
BACKGROUND: Whether catheter ablation (CA) is superior to amiodarone (AMIO) for the treatment of persistent atrial fibrillation (AF) in patients with heart failure is unknown. ...
BACKGROUND: Whether catheter ablation (CA) is superior to amiodarone (AMIO) for the treatment of persistent atrial fibrillation (AF) …
Amiodarone for arrhythmia in patients with Chagas disease: A systematic review and individual patient data meta-analysis.
Stein C, Migliavaca CB, Colpani V, da Rosa PR, Sganzerla D, Giordani NE, Miguel SRPS, Cruz LN, Polanczyk CA, Ribeiro ALP, Falavigna M. Stein C, et al. PLoS Negl Trop Dis. 2018 Aug 20;12(8):e0006742. doi: 10.1371/journal.pntd.0006742. eCollection 2018 Aug. PLoS Negl Trop Dis. 2018. PMID: 30125291 Free PMC article.
Ventricular arrhythmias are common in patients with Chagas cardiomyopathy, and amiodarone has been widely used for this purpose. The aim of our study was to assess the effect of amiodarone in patients with Chagas cardiomyopathy. ...Although our findings support the …
Ventricular arrhythmias are common in patients with Chagas cardiomyopathy, and amiodarone has been widely used for this purpose. The …
Amiodarone or lidocaine for cardiac arrest: A systematic review and meta-analysis.
Sanfilippo F, Corredor C, Santonocito C, Panarello G, Arcadipane A, Ristagno G, Pellis T. Sanfilippo F, et al. Resuscitation. 2016 Oct;107:31-7. doi: 10.1016/j.resuscitation.2016.07.235. Epub 2016 Aug 3. Resuscitation. 2016. PMID: 27496262 Review.
BACKGROUND: Guidelines for treatment of out-of-hospital cardiac arrest (OOH-CA) with shockable rhythm recommend amiodarone, while lidocaine may be used if amiodarone is not available. Recent underpowered evidence suggests that amiodarone, lidocaine or placebo …
BACKGROUND: Guidelines for treatment of out-of-hospital cardiac arrest (OOH-CA) with shockable rhythm recommend amiodarone, while lid …
Ocular Adverse Effects of Amiodarone: A Systematic Review of Case Reports.
Alshehri M, Joury A. Alshehri M, et al. Optom Vis Sci. 2020 Jul;97(7):536-542. doi: 10.1097/OPX.0000000000001534. Optom Vis Sci. 2020. PMID: 32697562
We used the MEDLINE database, primarily through PubMed, and used keywords (amiodarone, eye, eye diseases, visual/ocular adverse effects/manifestations) to identify case reports of ocular adverse effects after amiodarone use. ...Discontinuation of amiodarone w …
We used the MEDLINE database, primarily through PubMed, and used keywords (amiodarone, eye, eye diseases, visual/ocular adverse effec …
757 results