Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1968 1
1975 1
1978 1
1980 1
1982 1
1983 1
1985 6
1986 8
1987 5
1988 3
1989 6
1990 10
1991 8
1992 15
1993 20
1994 19
1995 13
1996 14
1997 18
1998 11
1999 27
2000 29
2001 15
2002 30
2003 39
2004 32
2005 21
2006 34
2007 31
2008 33
2009 27
2010 27
2011 29
2012 23
2013 23
2014 26
2015 23
2016 23
2017 29
2018 22
2019 17
2020 16
2021 19
2022 20
2023 12
2024 1

Text availability

Article attribute

Article type

Publication date

Search Results

736 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Amiodarone, Lidocaine, or Placebo in Out-of-Hospital Cardiac Arrest.
Kudenchuk PJ, Brown SP, Daya M, Rea T, Nichol G, Morrison LJ, Leroux B, Vaillancourt C, Wittwer L, Callaway CW, Christenson J, Egan D, Ornato JP, Weisfeldt ML, Stiell IG, Idris AH, Aufderheide TP, Dunford JV, Colella MR, Vilke GM, Brienza AM, Desvigne-Nickens P, Gray PC, Gray R, Seals N, Straight R, Dorian P; Resuscitation Outcomes Consortium Investigators. Kudenchuk PJ, et al. N Engl J Med. 2016 May 5;374(18):1711-22. doi: 10.1056/NEJMoa1514204. Epub 2016 Apr 4. N Engl J Med. 2016. PMID: 27043165 Free article. Clinical Trial.
RESULTS: In the per-protocol population, 3026 patients were randomly assigned to amiodarone (974), lidocaine (993), or placebo (1059); of those, 24.4%, 23.7%, and 21.0%, respectively, survived to hospital discharge. The difference in survival rate for amiodarone ver …
RESULTS: In the per-protocol population, 3026 patients were randomly assigned to amiodarone (974), lidocaine (993), or placebo (1059) …
Propafenone versus amiodarone for supraventricular arrhythmias in septic shock: a randomised controlled trial.
Balik M, Maly M, Brozek T, Rulisek J, Porizka M, Sachl R, Otahal M, Brestovansky P, Svobodova E, Flaksa M, Stach Z, Horejsek J, Volny L, Jurisinova I, Novotny A, Trachta P, Kunstyr J, Kopecky P, Tencer T, Pazout J, Belohlavek J, Duska F, Krajcova A, Waldauf P. Balik M, et al. Intensive Care Med. 2023 Nov;49(11):1283-1292. doi: 10.1007/s00134-023-07208-3. Epub 2023 Sep 12. Intensive Care Med. 2023. PMID: 37698594 Clinical Trial.
After 24 h, 77 (72.8%) and 71 (67.3%) were in sinus rhythm (p = 0.4), restored after a median of 3.7 h (95% CI 2.3-6.8) and 7.3 h (95% CI 5-11), p = 0.02, with propafenone and amiodarone, respectively. The arrhythmia recurred in 54 (52%) patients treated with propafenone a …
After 24 h, 77 (72.8%) and 71 (67.3%) were in sinus rhythm (p = 0.4), restored after a median of 3.7 h (95% CI 2.3-6.8) and 7.3 h (95% CI 5- …
Amiodarone or an implantable cardioverter-defibrillator for congestive heart failure.
Bardy GH, Lee KL, Mark DB, Poole JE, Packer DL, Boineau R, Domanski M, Troutman C, Anderson J, Johnson G, McNulty SE, Clapp-Channing N, Davidson-Ray LD, Fraulo ES, Fishbein DP, Luceri RM, Ip JH; Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT) Investigators. Bardy GH, et al. N Engl J Med. 2005 Jan 20;352(3):225-37. doi: 10.1056/NEJMoa043399. N Engl J Med. 2005. PMID: 15659722 Free article. Clinical Trial.
Placebo and amiodarone were administered in a double-blind fashion. The primary end point was death from any cause. ...CONCLUSIONS: In patients with NYHA class II or III CHF and LVEF of 35 percent or less, amiodarone has no favorable effect on survival, whereas sing …
Placebo and amiodarone were administered in a double-blind fashion. The primary end point was death from any cause. ...CONCLUSIONS: I …
Randomized comparison of intravenous procainamide vs. intravenous amiodarone for the acute treatment of tolerated wide QRS tachycardia: the PROCAMIO study.
Ortiz M, Martín A, Arribas F, Coll-Vinent B, Del Arco C, Peinado R, Almendral J; PROCAMIO Study Investigators. Ortiz M, et al. Eur Heart J. 2017 May 1;38(17):1329-1335. doi: 10.1093/eurheartj/ehw230. Eur Heart J. 2017. PMID: 27354046 Free PMC article. Clinical Trial.
AIMS: Intravenous procainamide and amiodarone are drugs of choice for well-tolerated ventricular tachycardia. ...Tachycardia terminated within 40 min in 22 (67%) procainamide and 11 (38%) amiodarone patients (OR = 3.3; 95% CI 1.2-9.3; P = 0.026). In the following 24 …
AIMS: Intravenous procainamide and amiodarone are drugs of choice for well-tolerated ventricular tachycardia. ...Tachycardia terminat …
Survival by time-to-administration of amiodarone, lidocaine, or placebo in shock-refractory out-of-hospital cardiac arrest.
Lupton JR, Neth MR, Sahni R, Jui J, Wittwer L, Newgard CD, Daya MR. Lupton JR, et al. Acad Emerg Med. 2023 Sep;30(9):906-917. doi: 10.1111/acem.14716. Epub 2023 Apr 5. Acad Emerg Med. 2023. PMID: 36869657 Clinical Trial.
BACKGROUND: Amiodarone and lidocaine have not been shown to have a clear survival benefit compared to placebo for out-of-hospital cardiac arrest (OHCA). ...We sought to evaluate how timing from emergency medical services (EMS) arrival on scene to drug administration affect …
BACKGROUND: Amiodarone and lidocaine have not been shown to have a clear survival benefit compared to placebo for out-of-hospital car …
Prevalence of amiodarone-induced hypothyroidism; A systematic review and meta-analysis.
Mohammadi K, Shafie D, Vakhshoori M, Bondariyan N, Rezvanian H, Heidarpour M. Mohammadi K, et al. Trends Cardiovasc Med. 2023 May;33(4):252-262. doi: 10.1016/j.tcm.2022.01.001. Epub 2022 Jan 11. Trends Cardiovasc Med. 2023. PMID: 35026394 Review.
Amiodarone is a common anti-arrhythmic agent mostly used to treat and prevent different kinds of arrhythmia with several considerable side effects, most commonly on the thyroid gland. We aimed to assess the frequency of hypothyroidism among chronic amiodarone users.
Amiodarone is a common anti-arrhythmic agent mostly used to treat and prevent different kinds of arrhythmia with several considerable
Ablation Versus Amiodarone for Treatment of Persistent Atrial Fibrillation in Patients With Congestive Heart Failure and an Implanted Device: Results From the AATAC Multicenter Randomized Trial.
Di Biase L, Mohanty P, Mohanty S, Santangeli P, Trivedi C, Lakkireddy D, Reddy M, Jais P, Themistoclakis S, Dello Russo A, Casella M, Pelargonio G, Narducci ML, Schweikert R, Neuzil P, Sanchez J, Horton R, Beheiry S, Hongo R, Hao S, Rossillo A, Forleo G, Tondo C, Burkhardt JD, Haissaguerre M, Natale A. Di Biase L, et al. Circulation. 2016 Apr 26;133(17):1637-44. doi: 10.1161/CIRCULATIONAHA.115.019406. Epub 2016 Mar 30. Circulation. 2016. PMID: 27029350 Free article. Clinical Trial.
BACKGROUND: Whether catheter ablation (CA) is superior to amiodarone (AMIO) for the treatment of persistent atrial fibrillation (AF) in patients with heart failure is unknown. ...
BACKGROUND: Whether catheter ablation (CA) is superior to amiodarone (AMIO) for the treatment of persistent atrial fibrillation (AF) …
Amiodarone and cardiac arrest: Systematic review and meta-analysis.
Laina A, Karlis G, Liakos A, Georgiopoulos G, Oikonomou D, Kouskouni E, Chalkias A, Xanthos T. Laina A, et al. Int J Cardiol. 2016 Oct 15;221:780-8. doi: 10.1016/j.ijcard.2016.07.138. Epub 2016 Jul 9. Int J Cardiol. 2016. PMID: 27434349 Review.
We reviewed the effects of amiodarone on survival and neurological outcome after cardiac arrest. ...CONCLUSIONS: Amiodarone significantly improves survival to hospital admission. However there is no benefit of amiodarone in survival to discharge or neurologic …
We reviewed the effects of amiodarone on survival and neurological outcome after cardiac arrest. ...CONCLUSIONS: Amiodarone si …
Amiodarone or lidocaine for cardiac arrest: A systematic review and meta-analysis.
Sanfilippo F, Corredor C, Santonocito C, Panarello G, Arcadipane A, Ristagno G, Pellis T. Sanfilippo F, et al. Resuscitation. 2016 Oct;107:31-7. doi: 10.1016/j.resuscitation.2016.07.235. Epub 2016 Aug 3. Resuscitation. 2016. PMID: 27496262 Review.
BACKGROUND: Guidelines for treatment of out-of-hospital cardiac arrest (OOH-CA) with shockable rhythm recommend amiodarone, while lidocaine may be used if amiodarone is not available. ...However, neither amiodarone nor lidocaine improve long-term outcome....
BACKGROUND: Guidelines for treatment of out-of-hospital cardiac arrest (OOH-CA) with shockable rhythm recommend amiodarone, while lid …
Amiodarone versus other pharmacological interventions for prevention of sudden cardiac death.
Claro JC, Candia R, Rada G, Baraona F, Larrondo F, Letelier LM. Claro JC, et al. Cochrane Database Syst Rev. 2015 Dec 8;2015(12):CD008093. doi: 10.1002/14651858.CD008093.pub2. Cochrane Database Syst Rev. 2015. PMID: 26646017 Free PMC article. Review.
SELECTION CRITERIA: Randomised and quasi-randomised trials assessing the efficacy of amiodarone versus placebo, no intervention, or other antiarrhythmics in adults. ...MAIN RESULTS: We included 24 studies (9,997 participants). Seventeen studies evaluated amiodarone
SELECTION CRITERIA: Randomised and quasi-randomised trials assessing the efficacy of amiodarone versus placebo, no intervention, or o …
736 results