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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1966 3
1967 1
1968 1
1969 1
1970 1
1971 1
1972 6
1973 1
1974 14
1975 6
1976 12
1977 6
1978 10
1979 17
1980 15
1981 11
1982 20
1983 20
1984 17
1985 20
1986 14
1987 13
1988 17
1989 31
1990 24
1991 18
1992 29
1993 24
1994 29
1995 23
1996 27
1997 18
1998 27
1999 13
2000 15
2001 23
2002 24
2003 22
2004 16
2005 22
2006 14
2007 20
2008 22
2009 27
2010 23
2011 28
2012 18
2013 31
2014 26
2015 20
2016 23
2017 25
2018 17
2019 2
2020 12
2021 17
2022 17
2023 14
2024 17
2025 6

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940 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Amitriptyline at Low-Dose and Titrated for Irritable Bowel Syndrome as Second-Line Treatment in primary care (ATLANTIS): a randomised, double-blind, placebo-controlled, phase 3 trial.
Ford AC, Wright-Hughes A, Alderson SL, Ow PL, Ridd MJ, Foy R, Bianco G, Bishop FL, Chaddock M, Cook H, Cooper D, Fernandez C, Guthrie EA, Hartley S, Herbert A, Howdon D, Muir DP, Nath T, Newman S, Smith T, Taylor CA, Teasdale EJ, Thornton R, Farrin AJ, Everitt HA; ATLANTIS trialists. Ford AC, et al. Lancet. 2023 Nov 11;402(10414):1773-1785. doi: 10.1016/S0140-6736(23)01523-4. Epub 2023 Oct 16. Lancet. 2023. PMID: 37858323 Free article. Clinical Trial.
FINDINGS: Between Oct 18, 2019, and April 11, 2022, 463 participants (mean age 48.5 years [SD 16.1], 315 [68%] female to 148 [32%] male) were randomly allocated to receive low-dose amitriptyline (232) or placebo (231). Intention-to-treat analysis of the primary outcome sho …
FINDINGS: Between Oct 18, 2019, and April 11, 2022, 463 participants (mean age 48.5 years [SD 16.1], 315 [68%] female to 148 [32%] male) wer …
Amitriptyline's anticholinergic adverse drug reactions-A systematic multiple-indication review and meta-analysis.
Brueckle MS, Thomas ET, Seide SE, Pilz M, Gonzalez-Gonzalez AI, Dinh TS, Gerlach FM, Harder S, Glasziou PP, Muth C. Brueckle MS, et al. PLoS One. 2023 Apr 5;18(4):e0284168. doi: 10.1371/journal.pone.0284168. eCollection 2023. PLoS One. 2023. PMID: 37018325 Free PMC article.
The primary outcome was frequency of anticholinergic ADRs as a binary outcome (absolute number of patients with/without anticholinergic ADRs) in amitriptyline vs. placebo groups. RESULTS: Twenty-three RCTs (mean dosage 5mg to 300mg amitriptyline/day) and 4217 patien …
The primary outcome was frequency of anticholinergic ADRs as a binary outcome (absolute number of patients with/without anticholinergic ADRs …
Amitriptyline for depression.
Guaiana G, Barbui C, Hotopf M. Guaiana G, et al. Cochrane Database Syst Rev. 2007 Jul 18;(3):CD004186. doi: 10.1002/14651858.CD004186.pub2. Cochrane Database Syst Rev. 2007. PMID: 17636748 Review.
The estimate of the efficacy of amitriptyline and control agents on a continuous outcome revealed an effect size which also significantly favoured amitriptyline (Standardised Mean Difference (SMD) 0.13, 95% CI 0.04 to 0.23). ...The dropout rate in patients taking …
The estimate of the efficacy of amitriptyline and control agents on a continuous outcome revealed an effect size which also significa …
Pregabalin and amitriptyline as first-line drugs among patients with painful peripheraldiabetic neuropathy: a systematic review and meta-analysis.
Alhowiti AM, Mirghani HO. Alhowiti AM, et al. Eur Rev Med Pharmacol Sci. 2024 May;28(10):3598-3606. doi: 10.26355/eurrev_202405_36296. Eur Rev Med Pharmacol Sci. 2024. PMID: 38856135 Free article.
OBJECTIVE: Painful peripheral diabetic neuropathy (PRDN) is a common disabling condition. Pregabalin and amitriptyline are commonly prescribed as the first-line for PPDN despite the contradicting recommendations. ...This meta-analysis assessed pregabalin and amitriptyli …
OBJECTIVE: Painful peripheral diabetic neuropathy (PRDN) is a common disabling condition. Pregabalin and amitriptyline are commonly p …
Amitriptyline for neuropathic pain in adults.
Moore RA, Derry S, Aldington D, Cole P, Wiffen PJ. Moore RA, et al. Cochrane Database Syst Rev. 2015 Jul 6;2015(7):CD008242. doi: 10.1002/14651858.CD008242.pub3. Cochrane Database Syst Rev. 2015. PMID: 26146793 Free PMC article. Review.
That review considered both fibromyalgia and neuropathic pain, but the effects of amitriptyline for fibromyalgia are now dealt with in a separate review.Amitriptyline is a tricyclic antidepressant that is widely used to treat chronic neuropathic pain (pain due to ne …
That review considered both fibromyalgia and neuropathic pain, but the effects of amitriptyline for fibromyalgia are now dealt with i …
Amitriptyline versus placebo for major depressive disorder.
Leucht C, Huhn M, Leucht S. Leucht C, et al. Cochrane Database Syst Rev. 2012 Dec 12;12(12):CD009138. doi: 10.1002/14651858.CD009138.pub2. Cochrane Database Syst Rev. 2012. PMID: 23235671 Free PMC article. Review.
OBJECTIVES: To assess the effects of amitriptyline compared to placebo or no treatment for major depressive disorder in adults. ...However, higher severity at baseline was associated with higher superiority of amitriptyline (P = 0.02), while higher responder rates i …
OBJECTIVES: To assess the effects of amitriptyline compared to placebo or no treatment for major depressive disorder in adults. ...Ho …
Amitriptyline for neuropathic pain and fibromyalgia in adults.
Moore RA, Derry S, Aldington D, Cole P, Wiffen PJ. Moore RA, et al. Cochrane Database Syst Rev. 2012 Dec 12;12:CD008242. doi: 10.1002/14651858.CD008242.pub2. Cochrane Database Syst Rev. 2012. Update in: Cochrane Database Syst Rev. 2015 Jul 06;(7):CD008242. doi: 10.1002/14651858.CD008242.pub3. PMID: 23235657 Updated. Review.
OBJECTIVES: To assess the analgesic efficacy of amitriptyline for chronic neuropathic pain and fibromyalgia.To assess the adverse events associated with the clinical use of amitriptyline for chronic neuropathic pain and fibromyalgia. ...The analysis showed that even …
OBJECTIVES: To assess the analgesic efficacy of amitriptyline for chronic neuropathic pain and fibromyalgia.To assess the adverse eve …
Amitriptyline versus other types of pharmacotherapy for depression.
Guaiana G, Barbui C, Hotopf M. Guaiana G, et al. Cochrane Database Syst Rev. 2003;(2):CD004186. doi: 10.1002/14651858.CD004186. Cochrane Database Syst Rev. 2003. Update in: Cochrane Database Syst Rev. 2007 Jul 18;(3):CD004186. doi: 10.1002/14651858.CD004186.pub2. PMID: 12804503 Updated. Review.
BACKGROUND: For many years amitriptyline has been considered one of the reference compounds for the pharmacological treatment of depression. ...The estimate of the efficacy of amitriptyline and control agents on a continuous outcome revealed an effect size which als …
BACKGROUND: For many years amitriptyline has been considered one of the reference compounds for the pharmacological treatment of depr …
Amitriptyline for inpatients and SSRIs for outpatients with depression? Systematic review and meta-regression analysis.
Barbui C, Guaiana G, Hotopf M. Barbui C, et al. Pharmacopsychiatry. 2004 May;37(3):93-7. doi: 10.1055/s-2004-818985. Pharmacopsychiatry. 2004. PMID: 15179966 Review.
Among inpatients amitriptyline was significantly more effective than TCA and nonsignificantly more effective than the SSRIs. Among outpatients no statistically significant differences emerged between amitriptyline and TCA and between amitriptyline and the SSR …
Among inpatients amitriptyline was significantly more effective than TCA and nonsignificantly more effective than the SSRIs. Among ou …
Antioxidants Supplementation in Acute Amitriptyline Abuse for Pain.
Ali SHK, Raja KWA, Irfan N, Habeeb M, Ismail Y. Ali SHK, et al. Appl Biochem Biotechnol. 2022 Jan;194(1):556-569. doi: 10.1007/s12010-021-03721-7. Epub 2021 Oct 26. Appl Biochem Biotechnol. 2022. PMID: 34699040 Clinical Trial.
The fundamental aim of this study is to establish the role of antioxidant supplementation in alleviating acute amitriptyline induced oxidative stress. The effect of supplementation was compared on treatment of acute amitriptyline intoxication cases for pain manageme …
The fundamental aim of this study is to establish the role of antioxidant supplementation in alleviating acute amitriptyline induced …
940 results

Searches related to "amitriptyline"