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Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1966 3
1967 1
1968 1
1969 1
1970 1
1971 1
1972 6
1973 1
1974 14
1975 6
1976 12
1977 6
1978 10
1979 17
1980 15
1981 11
1982 20
1983 20
1984 17
1985 20
1986 14
1987 13
1988 17
1989 31
1990 24
1991 18
1992 29
1993 24
1994 29
1995 23
1996 27
1997 18
1998 27
1999 13
2000 15
2001 23
2002 24
2003 22
2004 16
2005 22
2006 14
2007 20
2008 22
2009 27
2010 23
2011 28
2012 18
2013 31
2014 26
2015 20
2016 24
2017 26
2018 18
2019 2
2020 12
2021 17
2022 17
2023 14
2024 3

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924 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Amitriptyline at Low-Dose and Titrated for Irritable Bowel Syndrome as Second-Line Treatment in primary care (ATLANTIS): a randomised, double-blind, placebo-controlled, phase 3 trial.
Ford AC, Wright-Hughes A, Alderson SL, Ow PL, Ridd MJ, Foy R, Bianco G, Bishop FL, Chaddock M, Cook H, Cooper D, Fernandez C, Guthrie EA, Hartley S, Herbert A, Howdon D, Muir DP, Nath T, Newman S, Smith T, Taylor CA, Teasdale EJ, Thornton R, Farrin AJ, Everitt HA; ATLANTIS trialists. Ford AC, et al. Lancet. 2023 Nov 11;402(10414):1773-1785. doi: 10.1016/S0140-6736(23)01523-4. Epub 2023 Oct 16. Lancet. 2023. PMID: 37858323 Free article. Clinical Trial.
FINDINGS: Between Oct 18, 2019, and April 11, 2022, 463 participants (mean age 48.5 years [SD 16.1], 315 [68%] female to 148 [32%] male) were randomly allocated to receive low-dose amitriptyline (232) or placebo (231). Intention-to-treat analysis of the primary outcome sho …
FINDINGS: Between Oct 18, 2019, and April 11, 2022, 463 participants (mean age 48.5 years [SD 16.1], 315 [68%] female to 148 [32%] male) wer …
Amitriptyline for depression.
Guaiana G, Barbui C, Hotopf M. Guaiana G, et al. Cochrane Database Syst Rev. 2007 Jul 18;(3):CD004186. doi: 10.1002/14651858.CD004186.pub2. Cochrane Database Syst Rev. 2007. PMID: 17636748 Review.
The estimate of the efficacy of amitriptyline and control agents on a continuous outcome revealed an effect size which also significantly favoured amitriptyline (Standardised Mean Difference (SMD) 0.13, 95% CI 0.04 to 0.23). ...The dropout rate in patients taking …
The estimate of the efficacy of amitriptyline and control agents on a continuous outcome revealed an effect size which also significa …
Amitriptyline and Sexual Function: A Systematic Review Updated for Sexual Health Practice.
Chen LW, Chen MY, Lian ZP, Lin HS, Chien CC, Yin HL, Chu YH, Chen KY. Chen LW, et al. Am J Mens Health. 2018 Mar;12(2):370-379. doi: 10.1177/1557988317734519. Epub 2017 Oct 11. Am J Mens Health. 2018. PMID: 29019272 Free PMC article. Review.
Amitriptyline is an old drug but is still prevalently used as the first-line treatment for a variety of common diseases. ...Clinicians should caution and tailor the gender and disease vulnerability of amitriptyline in their practice....
Amitriptyline is an old drug but is still prevalently used as the first-line treatment for a variety of common diseases. ...Clinician
Amitriptyline for neuropathic pain in adults.
Moore RA, Derry S, Aldington D, Cole P, Wiffen PJ. Moore RA, et al. Cochrane Database Syst Rev. 2015 Jul 6;2015(7):CD008242. doi: 10.1002/14651858.CD008242.pub3. Cochrane Database Syst Rev. 2015. PMID: 26146793 Free PMC article. Review.
That review considered both fibromyalgia and neuropathic pain, but the effects of amitriptyline for fibromyalgia are now dealt with in a separate review.Amitriptyline is a tricyclic antidepressant that is widely used to treat chronic neuropathic pain (pain due to ne …
That review considered both fibromyalgia and neuropathic pain, but the effects of amitriptyline for fibromyalgia are now dealt with i …
Amitriptyline's anticholinergic adverse drug reactions-A systematic multiple-indication review and meta-analysis.
Brueckle MS, Thomas ET, Seide SE, Pilz M, Gonzalez-Gonzalez AI, Dinh TS, Gerlach FM, Harder S, Glasziou PP, Muth C. Brueckle MS, et al. PLoS One. 2023 Apr 5;18(4):e0284168. doi: 10.1371/journal.pone.0284168. eCollection 2023. PLoS One. 2023. PMID: 37018325 Free PMC article.
The primary outcome was frequency of anticholinergic ADRs as a binary outcome (absolute number of patients with/without anticholinergic ADRs) in amitriptyline vs. placebo groups. RESULTS: Twenty-three RCTs (mean dosage 5mg to 300mg amitriptyline/day) and 4217 patien …
The primary outcome was frequency of anticholinergic ADRs as a binary outcome (absolute number of patients with/without anticholinergic ADRs …
Amitriptyline versus placebo for major depressive disorder.
Leucht C, Huhn M, Leucht S. Leucht C, et al. Cochrane Database Syst Rev. 2012 Dec 12;12:CD009138. doi: 10.1002/14651858.CD009138.pub2. Cochrane Database Syst Rev. 2012. PMID: 23235671 Review.
BACKGROUND: Amitriptyline is a tricyclic antidepressant that was synthesised in 1960 and introduced as early as 1961 in the USA, but is still regularly used. ...However, higher severity at baseline was associated with higher superiority of amitriptyline (P = 0.02), …
BACKGROUND: Amitriptyline is a tricyclic antidepressant that was synthesised in 1960 and introduced as early as 1961 in the USA, but …
Amitriptyline versus other types of pharmacotherapy for depression.
Guaiana G, Barbui C, Hotopf M. Guaiana G, et al. Cochrane Database Syst Rev. 2003;(2):CD004186. doi: 10.1002/14651858.CD004186. Cochrane Database Syst Rev. 2003. PMID: 12804503 Updated. Review.
BACKGROUND: For many years amitriptyline has been considered one of the reference compounds for the pharmacological treatment of depression. ...The estimate of the efficacy of amitriptyline and control agents on a continuous outcome revealed an effect size which als …
BACKGROUND: For many years amitriptyline has been considered one of the reference compounds for the pharmacological treatment of depr …
Amitriptyline for neuropathic pain and fibromyalgia in adults.
Moore RA, Derry S, Aldington D, Cole P, Wiffen PJ. Moore RA, et al. Cochrane Database Syst Rev. 2012 Dec 12;12:CD008242. doi: 10.1002/14651858.CD008242.pub2. Cochrane Database Syst Rev. 2012. PMID: 23235657 Updated. Review.
These types of pain can be treated with antidepressant drugs in doses below those at which the drugs act as antidepressants. OBJECTIVES: To assess the analgesic efficacy of amitriptyline for chronic neuropathic pain and fibromyalgia.To assess the adverse events associated …
These types of pain can be treated with antidepressant drugs in doses below those at which the drugs act as antidepressants. OBJECTIVES: To …
Amitriptyline for inpatients and SSRIs for outpatients with depression? Systematic review and meta-regression analysis.
Barbui C, Guaiana G, Hotopf M. Barbui C, et al. Pharmacopsychiatry. 2004 May;37(3):93-7. doi: 10.1055/s-2004-818985. Pharmacopsychiatry. 2004. PMID: 15179966 Review.
Among inpatients amitriptyline was significantly more effective than TCA and nonsignificantly more effective than the SSRIs. Among outpatients no statistically significant differences emerged between amitriptyline and TCA and between amitriptyline and the SSR …
Among inpatients amitriptyline was significantly more effective than TCA and nonsignificantly more effective than the SSRIs. Among ou …
Antioxidants Supplementation in Acute Amitriptyline Abuse for Pain.
Ali SHK, Raja KWA, Irfan N, Habeeb M, Ismail Y. Ali SHK, et al. Appl Biochem Biotechnol. 2022 Jan;194(1):556-569. doi: 10.1007/s12010-021-03721-7. Epub 2021 Oct 26. Appl Biochem Biotechnol. 2022. PMID: 34699040 Clinical Trial.
The fundamental aim of this study is to establish the role of antioxidant supplementation in alleviating acute amitriptyline induced oxidative stress. The effect of supplementation was compared on treatment of acute amitriptyline intoxication cases for pain manageme …
The fundamental aim of this study is to establish the role of antioxidant supplementation in alleviating acute amitriptyline induced …
924 results