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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1954 1
1962 1
1963 1
1965 1
1969 1
1970 5
1971 30
1972 107
1973 172
1974 153
1975 119
1976 143
1977 138
1978 121
1979 97
1980 102
1981 126
1982 77
1983 76
1984 83
1985 73
1986 78
1987 68
1988 53
1989 45
1990 59
1991 90
1992 62
1993 68
1994 77
1995 107
1996 87
1997 112
1998 158
1999 156
2000 163
2001 208
2002 200
2003 228
2004 234
2005 269
2006 323
2007 382
2008 382
2009 340
2010 375
2011 376
2012 407
2013 336
2014 389
2015 364
2016 358
2017 349
2018 386
2019 428
2020 554
2021 501
2022 551
2023 444
2024 449
2025 115

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10,601 results

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Page 1
Analgesic Effects of Cannabinoids for Chronic Non-cancer Pain: a Systematic Review and Meta-Analysis with Meta-Regression.
Wong SSC, Chan WS, Cheung CW. Wong SSC, et al. J Neuroimmune Pharmacol. 2020 Dec;15(4):801-829. doi: 10.1007/s11481-020-09905-y. Epub 2020 Mar 14. J Neuroimmune Pharmacol. 2020. PMID: 32172501
There is growing interest in using cannabinoids for chronic pain. We performed a systematic review and meta-analysis of randomized controlled trials to evaluate the analgesic efficacy and adverse effects of cannabinoids for chronic non-cancer pain. ... …
There is growing interest in using cannabinoids for chronic pain. We performed a systematic review and meta-analysis of randomized co …
An experimental randomized study on the analgesic effects of pharmaceutical-grade cannabis in chronic pain patients with fibromyalgia.
van de Donk T, Niesters M, Kowal MA, Olofsen E, Dahan A, van Velzen M. van de Donk T, et al. Pain. 2019 Apr;160(4):860-869. doi: 10.1097/j.pain.0000000000001464. Pain. 2019. PMID: 30585986 Free PMC article. Clinical Trial.
In this experimental randomized placebo-controlled 4-way crossover trial, we explored the analgesic effects of inhaled pharmaceutical-grade cannabis in 20 chronic pain patients with fibromyalgia. ...This experimental trial shows the complex behavior of inhaled ca …
In this experimental randomized placebo-controlled 4-way crossover trial, we explored the analgesic effects of inhaled pharmac …
Cannabinoids and the expanded endocannabinoid system in neurological disorders.
Cristino L, Bisogno T, Di Marzo V. Cristino L, et al. Nat Rev Neurol. 2020 Jan;16(1):9-29. doi: 10.1038/s41582-019-0284-z. Epub 2019 Dec 12. Nat Rev Neurol. 2020. PMID: 31831863 Review.
Anecdotal evidence that cannabis preparations have medical benefits together with the discovery of the psychotropic plant cannabinoid delta(9)-tetrahydrocannabinol (THC) initiated efforts to develop cannabinoid-based therapeutics. These efforts have been marked by d …
Anecdotal evidence that cannabis preparations have medical benefits together with the discovery of the psychotropic plant cannabinoid …
Cannabidiol for Pain Treatment: Focus on Pharmacology and Mechanism of Action.
Mlost J, Bryk M, Starowicz K. Mlost J, et al. Int J Mol Sci. 2020 Nov 23;21(22):8870. doi: 10.3390/ijms21228870. Int J Mol Sci. 2020. PMID: 33238607 Free PMC article. Review.
Therefore, we review the basic research regarding molecular mechanism of CBD's action with particular focus on its analgesic potential. Moreover, this article describes the detailed analgesic and anti-inflammatory effects of CBD in various models, including n …
Therefore, we review the basic research regarding molecular mechanism of CBD's action with particular focus on its analgesic potentia …
Cannabinoids, cannabis, and cannabis-based medicine for pain management: a systematic review of randomised controlled trials.
Fisher E, Moore RA, Fogarty AE, Finn DP, Finnerup NB, Gilron I, Haroutounian S, Krane E, Rice ASC, Rowbotham M, Wallace M, Eccleston C. Fisher E, et al. Pain. 2021 Jul 1;162(Suppl 1):S45-S66. doi: 10.1097/j.pain.0000000000001929. Pain. 2021. PMID: 32804836
Cannabinoids, cannabis, and cannabis-based medicines (CBMs) are increasingly used to manage pain, with limited understanding of their efficacy and safety. ...We have little confidence in the estimates of effect. The evidence neither supports nor refutes claims of ef …
Cannabinoids, cannabis, and cannabis-based medicines (CBMs) are increasingly used to manage pain, with limited understanding of their …
In vitro and in vivo pharmacological activity of minor cannabinoids isolated from Cannabis sativa.
Zagzoog A, Mohamed KA, Kim HJJ, Kim ED, Frank CS, Black T, Jadhav PD, Holbrook LA, Laprairie RB. Zagzoog A, et al. Sci Rep. 2020 Nov 23;10(1):20405. doi: 10.1038/s41598-020-77175-y. Sci Rep. 2020. PMID: 33230154 Free PMC article.
The Cannabis sativa plant contains more than 120 cannabinoids. With the exceptions of (9)-tetrahydrocannabinol ((9)-THC) and cannabidiol (CBD), comparatively little is known about the pharmacology of the less-abundant plant-derived (phyto) cannabinoids. The best-stu …
The Cannabis sativa plant contains more than 120 cannabinoids. With the exceptions of (9)-tetrahydrocannabinol ((9)-THC) and cannabid …
Antinociceptive effects of minor cannabinoids, terpenes and flavonoids in Cannabis.
Rodriguez CEB, Ouyang L, Kandasamy R. Rodriguez CEB, et al. Behav Pharmacol. 2022 Apr 1;33(2&3):130-157. doi: 10.1097/FBP.0000000000000627. Behav Pharmacol. 2022. PMID: 33709984 Review.
Given the dangerous and unpleasant side effects of existing analgesics, the chemical constituents of Cannabis have garnered significant interest for their antinociceptive, anti-inflammatory and neuroprotective effects. ...Although the analgesic effe …
Given the dangerous and unpleasant side effects of existing analgesics, the chemical constituents of Cannabis have garnered si …
ASRA Pain Medicine consensus guidelines on the management of the perioperative patient on cannabis and cannabinoids.
Shah S, Schwenk ES, Sondekoppam RV, Clarke H, Zakowski M, Rzasa-Lynn RS, Yeung B, Nicholson K, Schwartz G, Hooten WM, Wallace M, Viscusi ER, Narouze S. Shah S, et al. Reg Anesth Pain Med. 2023 Mar;48(3):97-117. doi: 10.1136/rapm-2022-104013. Epub 2023 Jan 3. Reg Anesth Pain Med. 2023. PMID: 36596580
The Perioperative Use of Cannabis and Cannabinoids Guidelines Committee was charged with drafting responses to the nine key questions using a modified Delphi method with the overall goal of producing a document focused on the safe management of surgical patients using c …
The Perioperative Use of Cannabis and Cannabinoids Guidelines Committee was charged with drafting responses to the nine key questions …
A Systematic Review on Cannabis Hyperemesis Syndrome and Its Management Options.
Senderovich H, Patel P, Jimenez Lopez B, Waicus S. Senderovich H, et al. Med Princ Pract. 2022;31(1):29-38. doi: 10.1159/000520417. Epub 2021 Nov 1. Med Princ Pract. 2022. PMID: 34724666 Free PMC article.
CHS is a condition that leads to repeated and severe N/V in long-term users of cannabinoids. OBJECTIVE: The aim of this study was to outline current treatments for the management of CHS. ...CONCLUSION: More research on CHS is needed to enhance knowledge translation, educat …
CHS is a condition that leads to repeated and severe N/V in long-term users of cannabinoids. OBJECTIVE: The aim of this study was to …
Cannabis and cannabinoids for symptomatic treatment for people with multiple sclerosis.
Filippini G, Minozzi S, Borrelli F, Cinquini M, Dwan K. Filippini G, et al. Cochrane Database Syst Rev. 2022 May 5;5(5):CD013444. doi: 10.1002/14651858.CD013444.pub2. Cochrane Database Syst Rev. 2022. PMID: 35510826 Free PMC article. Review.
OBJECTIVES: To assess benefit and harms of cannabinoids, including synthetic, or herbal and plant-derived cannabinoids, for reducing symptoms for adults with MS. ...SELECTION CRITERIA: We included randomised parallel or cross-over trials (RCTs) evaluating any can …
OBJECTIVES: To assess benefit and harms of cannabinoids, including synthetic, or herbal and plant-derived cannabinoids, for re …
10,601 results
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