Arginine metabolism is a biomarker of red blood cell and human aging.
Reisz JA, Earley EJ, Nemkov T, Key A, Stephenson D, Keele GR, Dzieciatkowska M, Spitalnik SL, Hod EA, Kleinman S, Roubinian NH, Gladwin MT, Hansen KC, Norris PJ, Busch MP, Zimring JC, Churchill GA, Page GP, D'Alessandro A.
Reisz JA, et al. Among authors: d alessandro a.
Aging Cell. 2025 Feb;24(2):e14388. doi: 10.1111/acel.14388. Epub 2024 Oct 30.
Aging Cell. 2025.
PMID: 39478346
Free PMC article.
This study examines age-associated changes in red blood cells (RBCs), the most numerous host cell in humans. Four cohorts, including healthy individuals and patients with sickle cell disease, were analyzed to define age-dependent changes in RBC metabol …
This study examines age-associated changes in red blood cells (RBCs), the most numerous host cell in humans. Four cohor …