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Angiotensin II impairs glucose utilization in obese Zucker rats by increasing HPA activity via an adrenal-dependent mechanism.
Müller-Fielitz H, Raasch W. Müller-Fielitz H, et al. Horm Metab Res. 2013 Feb;45(2):173-80. doi: 10.1055/s-0032-1327679. Epub 2012 Oct 26. Horm Metab Res. 2013. PMID: 23104420
Angiotensin II (AngII) increases the activity of the hypothalamus-pituitary-adrenal (HPA) axis. We have previously demonstrated in obese Zucker rats (OZR) that AngII-induced HPA hyperreactivity was associated with impaire
Angiotensin II (AngII) increases the activity of the hypothalamus-pituitary-adrenal (HPA) axis. We have previous
Angiotensin II stimulates the reactivity of the pituitary-adrenal axis in leptin-resistant Zucker rats, thereby influencing the glucose utilization.
Müller H, Schweitzer N, Jöhren O, Dominiak P, Raasch W. Müller H, et al. Am J Physiol Endocrinol Metab. 2007 Sep;293(3):E802-10. doi: 10.1152/ajpendo.00650.2006. Epub 2007 Jun 26. Am J Physiol Endocrinol Metab. 2007. PMID: 17595220 Free article.
We hypothesized that a hyperreactivity of the HPA axis to ANG contributes to an impaired glucose utilization in obesity, since leptin resistance and an overactive renin-angiotensin-aldosterone system are features of obesity. ...In …
We hypothesized that a hyperreactivity of the HPA axis to ANG contributes to an impaired glucose utilization in …