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2001 1
2002 13
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2008 22
2009 22
2010 31
2011 20
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2014 30
2015 25
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2023 26
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Page 1
Design and methods of an adaptive trial to test comparative effectiveness of readmission reduction approaches following infection and sepsis hospitalizations (ACCOMPLISH).
Mayes K, Talisa VB, Malito A, Mayr FB, Williams K, Char K, Wadas R, Lorenzi E, Viele K, Awdish R, Angus DC, Chang CH, Yende S. Mayes K, et al. Among authors: angus dc. Contemp Clin Trials Commun. 2025 Jun 19;46:101504. doi: 10.1016/j.conctc.2025.101504. eCollection 2025 Aug. Contemp Clin Trials Commun. 2025. PMID: 40642111 Free PMC article.
Implementing Artificial Intelligence in Critical Care Medicine: a consensus of 22.
Cecconi M, Greco M, Shickel B, Angus DC, Bailey H, Bignami E, Calandra T, Celi LA, Einav S, Elbers P, Ercole A, Gómez H, Gong MN, Komorowski M, Liu V, Park S, Sarwal A, Seymour CW, Zampieri FG, Taccone FS, Vincent JL, Bihorac A. Cecconi M, et al. Among authors: angus dc. Crit Care. 2025 Jul 8;29(1):290. doi: 10.1186/s13054-025-05532-2. Crit Care. 2025. PMID: 40629428 Free PMC article. Review.
Hurdles for the Delivery of Multinational Randomized Clinical Trials.
van Hout D, Mouncey P, Harrison D, Bonten M, Derde L; REMAP-CAP European Regional Investigators; Angus DC, Anjum A, Annane D, Best-Lane J, Brunkhorst F, Cecconi M, Ehrmann S, Gordon A, Hays LM, Kester E, Mahon N, McArthur C, Nichol A, Peters S, Pugliese S, Rowan K, Torre-Cisneros J, Weis S. van Hout D, et al. Among authors: angus dc. JAMA Netw Open. 2025 Jul 1;8(7):e2518503. doi: 10.1001/jamanetworkopen.2025.18503. JAMA Netw Open. 2025. PMID: 40601320 Free PMC article.
The authors reply.
Angus DC, Yende SP, Shah FA, Yealy DM; Protocolized Resuscitation in Sepsis Meta-Analysis (PRISM) Investigators. Angus DC, et al. Crit Care Med. 2025 Jul 1;53(7):e1524-e1525. doi: 10.1097/CCM.0000000000006694. Epub 2025 Jul 1. Crit Care Med. 2025. PMID: 40590651 No abstract available.
Strategies to Promote Resiliency: A Randomized Embedded Multifactorial Adaptative Platform (REMAP) Clinical Trial to Study Interventions to Improve Recovery After Surgery in High-Risk Patients.
Reitz KM, Nassereldine H, Kennedy J, Zeh R, Khandwala F, Seymour CW, Quintana M, Viele K, Detry M, Morris A, Methe B, Zuckerbraun B, Girard TD, Marroquin OC, Esper S, Holder-Murray J, Newman AB, Billiar TR, Berry S, Angus DC, Neal MD. Reitz KM, et al. Among authors: angus dc. Ann Surg Open. 2025 Apr 2;6(2):e566. doi: 10.1097/AS9.0000000000000566. eCollection 2025 Jun. Ann Surg Open. 2025. PMID: 40557356 Free PMC article.
An Educational Video Game in Trauma Triage at Nontrauma Centers: A Secondary Analysis of a Randomized Clinical Trial.
Mohan D, Fischhoff B, Talisa V, Elmer J, White DB, Angus DC, Peitzman A, Bendesky B, Chapman AC, Forsythe RM, Guyette FX, Hynes AM, Oskvarek JJ, Weingart SD, Weinstock M, Chang CH. Mohan D, et al. Among authors: angus dc. JAMA Netw Open. 2025 Jun 2;8(6):e2513375. doi: 10.1001/jamanetworkopen.2025.13375. JAMA Netw Open. 2025. PMID: 40465299 Free PMC article. Clinical Trial.
Tocilizumab, sarilumab and anakinra in critically ill patients with COVID-19: a randomised, controlled, open-label, adaptive platform trial.
Derde L, Gordon AC, Mouncey PR, Al-Beidh F, Rowan KM, Nichol AD, Arabi YM, Annane D, Beane A, Beasley R, Bonten MJM, Bradbury CA, Brunkhorst FM, Buzgau A, Buxton M, Cheng AC, Cooper N, Cove M, Cremer OL, Detry MA, Duffy EJ, Estcourt LJ, Fitzgerald M, Galea J, Goossens H, Haniffa R, Hills TE, Huang DT, Ichihara N, King A, Lamontagne F, Lawler PR, Leavis HL, Lewis RJ, Litton E, Marshall JC, Mayr FB, McAuley DF, McGlothlin A, McGuinness SP, McVerry BJ, Morpeth SC, Murthy S, Netea MG, Ogungbenro K, Orr K, Parke RL, Parker JC, Patanwala AE, Pettila V, Reyes LF, Saito H, Santos MS, Saunders CT, Seymour CW, Shankar-Hari M, Sligl WI, Turgeon AF, Turner AM, Tong SYC, Vaara S, Youngstein T, Zarychanski R, Green C, Higgins AM, McArthur CJ, Berry LR, Lorenzi E, Berry S, Webb SA, Angus DC, van de Veerdonk FL. Derde L, et al. Among authors: angus dc. Thorax. 2025 Jul 15;80(8):530-539. doi: 10.1136/thorax-2024-222488. Thorax. 2025. PMID: 40360262 Free article. Clinical Trial.
Corticosteroids for adult patients hospitalised with non-viral community-acquired pneumonia: a systematic review and meta-analysis.
Pitre T, Pauley E, Chaudhuri D, Saha R, Rudd KE, Villar J, Berry LR, Lorenzi E, Hills T, Nichol A, Harrison DA, Finfer S, Cohen J, Myburgh J, Hammond N, Martínez D, Fernández C, Antcliffe D, Gordon A, Scherag A, Bogatsch H, Brunkhorst FM, Venkatesh B, Annane D, McAuley D, Angus DC, Rochwerg B, Shankar-Hari M. Pitre T, et al. Among authors: angus dc. Intensive Care Med. 2025 May;51(5):917-929. doi: 10.1007/s00134-025-07912-2. Epub 2025 May 5. Intensive Care Med. 2025. PMID: 40323455
Evidence-based personalised medicine in critical care: a framework for quantifying and applying individualised treatment effects in patients who are critically ill.
Munroe ES, Spicer A, Castellvi-Font A, Zalucky A, Dianti J, Graham Linck E, Talisa V, Urner M, Angus DC, Baedorf-Kassis E, Blette B, Bos LD, Buell KG, Casey JD, Calfee CS, Del Sorbo L, Estenssoro E, Ferguson ND, Giblon R, Granholm A, Harhay MO, Heath A, Hodgson C, Houle T, Jiang C, Kramer L, Lawler PR, Leligdowicz A, Li F, Liu K, Maiga A, Maslove D, McArthur C, McAuley DF, Serpa Neto A, Oosthuysen C, Perner A, Prescott HC, Rochwerg B, Sahetya S, Samoilenko M, Schnitzer ME, Seitz KP, Shah F, Shankar-Hari M, Sinha P, Slutsky AS, Qian ET, Webb SA, Young PJ, Zampieri FG, Zarychanski R, Fan E, Semler MW, Churpek M, Goligher EC; Platform of Randomized Adaptive Clinical Trials in Critical Illness (PRACTICAL) investigators; Evidence-based Individualized Treatment Effects (EvITE) Group. Munroe ES, et al. Among authors: angus dc. Lancet Respir Med. 2025 Jun;13(6):556-568. doi: 10.1016/S2213-2600(25)00054-2. Epub 2025 Apr 15. Lancet Respir Med. 2025. PMID: 40250459 Review.
Microsampling in toxicology studies - maximising the scientific, business and 3Rs advantages.
Prior H, Adedeji AO, Allen R, Angus D, Baker D, Blunt H, Coleman D, Dunmore HM, Passini E, Putnam T, Rosseels ML, Spooner N, Stewart J, Strepka C, Stokes A, Verhaeghe T, Wilson A, Sewell F. Prior H, et al. Among authors: angus d. Toxicol Res (Camb). 2025 Mar 31;14(2):tfaf045. doi: 10.1093/toxres/tfaf045. eCollection 2025 Apr. Toxicol Res (Camb). 2025. PMID: 40165820 Free PMC article.
Do Sepsis Alerts Help?
Angus DC. Angus DC. JAMA. 2025 Mar 4;333(9):759-760. doi: 10.1001/jama.2024.25818. JAMA. 2025. PMID: 39658870 No abstract available.
On-Treatment Change in d-Dimer Is Associated With Differential Outcomes Among Therapeutic Dose Heparin-Treated Noncritically Ill Patients Hospitalized for COVID-19.
Wahid L, Froess JD, Ortel TL, Zarychanski R, Berger JS, Cushman M, Angus DC, Renard V, Farahani P, Webb S, Heath A, Godoy LC, Farkouh ME, Hochman JS, Neal MD, Lawler PR. Wahid L, et al. Among authors: angus dc. Arterioscler Thromb Vasc Biol. 2025 Jan;45(1):162-164. doi: 10.1161/ATVBAHA.124.321108. Epub 2024 Dec 5. Arterioscler Thromb Vasc Biol. 2025. PMID: 39633573
Randomized Clinical Trial of the Four Supports Intervention for Surrogate Decision-Makers in Intensive Care Units.
Butler RA, Seaman JB, Felman K, Stonehouse W, San Pedro R, Morse JQ, Chang CH, Lincoln T, Reynolds CF 3rd, Landefeld S, Happ MB, Song MK, Angus DC, Arnold RM, White DB. Butler RA, et al. Among authors: angus dc. Am J Respir Crit Care Med. 2025 Mar;211(3):370-380. doi: 10.1164/rccm.202405-0931OC. Am J Respir Crit Care Med. 2025. PMID: 39586017 Clinical Trial.
Heterogeneity in the Effect of Early Goal-Directed Therapy for Septic Shock: A Secondary Analysis of Two Multicenter International Trials.
Shah FA, Talisa VB, Chang CH, Triantafyllou S, Tang L, Mayr FB, Higgins AM, Peake SL, Mouncey P, Harrison DA, DeMerle KM, Kennedy JN, Cooper GF, Bellomo R, Rowan K, Yealy DM, Seymour CW, Angus DC, Yende SP. Shah FA, et al. Among authors: angus dc. Crit Care Med. 2025 Jan 1;53(1):e4-e14. doi: 10.1097/CCM.0000000000006463. Epub 2024 Oct 23. Crit Care Med. 2025. PMID: 39440873 Clinical Trial.
Causal inference can lead us to modifiable mechanisms and informative archetypes in sepsis.
Baillie JK, Angus D, Burnham K, Calandra T, Calfee C, Gutteridge A, Hacohen N, Khatri P, Langley R, Ma'ayan A, Marshall J, Maslove D, Prescott HC, Rowan K, Scicluna BP, Seymour C, Shankar-Hari M, Shapiro N, Joost Wiersinga W, Singer M, Randolph AG. Baillie JK, et al. Among authors: angus d. Intensive Care Med. 2024 Dec;50(12):2031-2042. doi: 10.1007/s00134-024-07665-4. Epub 2024 Oct 21. Intensive Care Med. 2024. PMID: 39432104 Free PMC article. Review.
Definitions of adverse events associated with extracorporeal membrane oxygenation in children: results of an international Delphi process from the ECMO-CENTRAL ARC.
Alexander PMA, Di Nardo M, Combes A, Vogel AM, Antonini MV, Barrett N, Benedetti GM, Bettencourt A, Brodie D, Gómez-Gutiérrez R, Gorga SM, Hodgson C, Kapoor PM, Le J, MacLaren G, O'Neil ER, Ostermann M, Paden ML, Patel N, Rojas-Peña A, Said AS, Sperotto F, Willems A, Vercaemst L, Yoganathan AP, Lorts A, Del Nido PJ, Barbaro RP; Extracorporeal Life Support Organization (ELSO); International ECMO Network (ECMONet); Pediatric Acute Lung Injury and Sepsis Investigators (PALISI); Pediatric ECMO subgroup of PALISI and ELSO (PediECMO); European Society of Paediatric and Neonatal Intensive Care (ESPNIC); Australian and New Zealand Intensive Care Society Paediatric Study Group (ANZICS PSG); Intensive Care Society (ICS); Pediatric Cardiac Intensive Care Society (PCICS); Advanced Cardiac Therapies Improving Outcomes Network (ACTION); Children's Hospitals Neonatal Consortium (CHNC); American Pediatric Surgical Association (APSA); Society of Thoracic Surgeons (STS); Society of Critical Care Medicine (SCCM). Alexander PMA, et al. Lancet Child Adolesc Health. 2024 Oct;8(10):773-780. doi: 10.1016/S2352-4642(24)00132-9. Lancet Child Adolesc Health. 2024. PMID: 39299748 Review.
Recommendations for clinical trial design in acute kidney injury from the 31st acute disease quality initiative consensus conference. A consensus statement.
Zarbock A, Forni LG, Koyner JL, Bell S, Reis T, Meersch M, Bagshaw SM, Fuhmann DY, Liu KD, Pannu N, Arikan AA, Angus DC, Duquette D, Goldstein SL, Hoste E, Joannidis M, Jongs N, Legrand M, Mehta RL, Murray PT, Nadim MK, Ostermann M, Prowle J, See EJ, Selby NM, Shaw AD, Srisawat N, Ronco C, Kellum JA. Zarbock A, et al. Among authors: angus dc. Intensive Care Med. 2024 Sep;50(9):1426-1437. doi: 10.1007/s00134-024-07560-y. Epub 2024 Aug 8. Intensive Care Med. 2024. PMID: 39115567 Free PMC article.
A randomized, embedded, pragmatic, Bayesian clinical trial examining clinical decision support for high flow nasal cannula management in children with bronchiolitis: design and statistical analysis plan.
Horvat CM, Suresh S, James N, Aneja RK, Au AK, Berry S, Blumer A, Bricker K, Clark RSB, Dolinich H, Hahner S, Jockel C, Kalivoda J, Loar I, Marasco D, Marcinick A, Marroquin O, O'brien J, Pelletier J, Ramgopal S, Venkataraman S, Angus DC, Butler G. Horvat CM, et al. Among authors: angus dc. Trials. 2024 Jul 16;25(1):484. doi: 10.1186/s13063-024-08327-y. Trials. 2024. PMID: 39014495 Free PMC article.
Impact of a family support intervention on hospitalization costs and hospital readmissions among ICU patients at high risk of death or severe functional impairment.
Andersen SK, Chang CH, Arnold RM, Pidro C, Darby JM, Angus DC, White DB; Pairing Re-engineered Intensive Care Teams with Nurse-driven Emotional Support, Relationship building (PARTNER) Investigators. Andersen SK, et al. Among authors: angus dc. Ann Intensive Care. 2024 Jul 2;14(1):103. doi: 10.1186/s13613-024-01344-9. Ann Intensive Care. 2024. PMID: 38954149 Free PMC article.
Automatic Population of the Case Report Forms for an International Multifactorial Adaptive Platform Trial Amid the COVID-19 Pandemic.
King AJ, Higgins L, Au C, Malakouti S, Music E, Kalchthaler K, Clermont G, Garrard W, Huang DT, McVerry BJ, Seymour CW, Linstrum K, McNamara A, Green C, Loar I, Roberts T, Marroquin O, Angus DC, Horvat CM. King AJ, et al. Among authors: angus dc. AMIA Jt Summits Transl Sci Proc. 2024 May 31;2024:276-284. eCollection 2024. AMIA Jt Summits Transl Sci Proc. 2024. PMID: 38827056 Free PMC article.
Early trajectories of virological and immunological biomarkers and clinical outcomes in patients admitted to hospital for COVID-19: an international, prospective cohort study.
Jensen TO, Murray TA, Grandits GA, Jain MK, Grund B, Shaw-Saliba K, Matthay MA, Abassi M, Ardelt M, Baker JV, Chen P, Dewar RL, Goodman AL, Hatlen TJ, Highbarger HC, Holodniy M, Lallemand P, Laverdure S, Leshnower BG, Looney D, Moschopoulos CD, Mugerwa H, Murray DD, Mylonakis E, Nagy-Agren S, Rehman MT, Rupert A, Stevens R, Turville S, Weintrob A, Wick K, Lundgren J, Ko ER; ACTIV-3/TICO Study Group. Jensen TO, et al. Lancet Microbe. 2024 Jun;5(6):e559-e569. doi: 10.1016/S2666-5247(24)00015-6. Epub 2024 May 27. Lancet Microbe. 2024. PMID: 38815595 Free PMC article.
Acetaminophen for Prevention and Treatment of Organ Dysfunction in Critically Ill Patients With Sepsis: The ASTER Randomized Clinical Trial.
Ware LB, Files DC, Fowler A, Aboodi MS, Aggarwal NR, Brower RG, Chang SY, Douglas IS, Fields S, Foulkes AS, Ginde AA, Harris ES, Hendey GW, Hite RD, Huang W, Lai P, Liu KD, Thompson BT, Matthay MA; National Heart, Lung, and Blood Institute Prevention and Early Treatment of Acute Lung Injury Clinical Trials Network. Ware LB, et al. JAMA. 2024 Aug 6;332(5):390-400. doi: 10.1001/jama.2024.8772. JAMA. 2024. PMID: 38762798 Free PMC article. Clinical Trial.
Correction: Phase-3 trial of recombinant human alkaline phosphatase for patients with sepsis-associated acute kidney injury (REVIVAL).
Pickkers P, Angus DC, Bass K, Bellomo R, van den Berg E, Bernholz J, Bestle MH, Doi K, Doig CJ, Ferrer R, Francois B, Gammelager H, Pedersen UG, Hoste E, Iversen S, Joannidis M, Kellum JA, Liu K, Meersch M, Mehta R, Millington S, Murray PT, Nichol A, Ostermann M, Pettilä V, Solling C, Winkel M, Young PJ, Zarbock A; REVIVAL investigators. Pickkers P, et al. Among authors: angus dc. Intensive Care Med. 2024 Apr;50(4):614-615. doi: 10.1007/s00134-024-07357-z. Intensive Care Med. 2024. PMID: 38436728 Free PMC article. No abstract available.
Viral and Host Factors Are Associated With Mortality in Hospitalized Patients With COVID-19.
Aggarwal NR, Nordwall J, Braun DL, Chung L, Coslet J, Der T, Eriobu N, Ginde AA, Hayanga AJ, Highbarger H, Holodniy M, Horcajada JP, Jain MK, Kim K, Laverdure S, Lundgren J, Natarajan V, Nguyen HH, Pett SL, Phillips A, Poulakou G, Price DA, Robinson P, Rogers AJ, Sandkovsky U, Shaw-Saliba K, Sturek JM, Trautner BW, Waters M, Reilly C; ACTIV-3/TICO Study Group. Aggarwal NR, et al. Clin Infect Dis. 2024 Jun 14;78(6):1490-1503. doi: 10.1093/cid/ciad780. Clin Infect Dis. 2024. PMID: 38376212 Free PMC article. Clinical Trial.
Author Correction: Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19 from an international collaborative meta-analysis of randomized trials.
Axfors C, Schmitt AM, Janiaud P, Van't Hooft J, Abd-Elsalam S, Abdo EF, Abella BS, Akram J, Amaravadi RK, Angus DC, Arabi YM, Azhar S, Baden LR, Baker AW, Belkhir L, Benfield T, Berrevoets MAH, Chen CP, Chen TC, Cheng SH, Cheng CY, Chung WS, Cohen YZ, Cowan LN, Dalgard O, de Almeida E Val FF, de Lacerda MVG, de Melo GC, Derde L, Dubee V, Elfakir A, Gordon AC, Hernandez-Cardenas CM, Hills T, Hoepelman AIM, Huang YW, Igau B, Jin R, Jurado-Camacho F, Khan KS, Kremsner PG, Kreuels B, Kuo CY, Le T, Lin YC, Lin WP, Lin TH, Lyngbakken MN, McArthur C, McVerry BJ, Meza-Meneses P, Monteiro WM, Morpeth SC, Mourad A, Mulligan MJ, Murthy S, Naggie S, Narayanasamy S, Nichol A, Novack LA, O'Brien SM, Okeke NL, Perez L, Perez-Padilla R, Perrin L, Remigio-Luna A, Rivera-Martinez NE, Rockhold FW, Rodriguez-Llamazares S, Rolfe R, Rosa R, Røsjø H, Sampaio VS, Seto TB, Shahzad M, Soliman S, Stout JE, Thirion-Romero I, Troxel AB, Tseng TY, Turner NA, Ulrich RJ, Walsh SR, Webb SA, Weehuizen JM, Velinova M, Wong HL, Wrenn R, Zampieri FG, Zhong W, Moher D, Goodman SN, Ioannidis JPA, Hemkens LG. Axfors C, et al. Among authors: angus dc. Nat Commun. 2024 Feb 5;15(1):1075. doi: 10.1038/s41467-024-45360-6. Nat Commun. 2024. PMID: 38316844 Free PMC article. No abstract available.
A Prospective Cohort Protocol for the Remnant Investigation in Sepsis Study.
Seymour CW, Urbanek KL, Nakayama A, Kennedy JN, Powell R, Robinson RAS, Kapp KL, Billiar TR, Vodovotz Y, Gelhaus SL, Cooper VS, Tang L, Mayr F, Reitz KM, Horvat C, Meyer NJ, Dickson RP, Angus D, Palmer OP. Seymour CW, et al. Among authors: angus d. Crit Care Explor. 2023 Oct 27;5(11):e0974. doi: 10.1097/CCE.0000000000000974. eCollection 2023 Nov. Crit Care Explor. 2023. PMID: 38304708 Free PMC article.
The trajectory of very old critically ill patients.
Guidet B, Vallet H, Flaatten H, Joynt G, Bagshaw SM, Leaver SK, Beil M, Du B, Forte DN, Angus DC, Sviri S, de Lange D, Herridge MS, Jung C. Guidet B, et al. Among authors: angus dc. Intensive Care Med. 2024 Feb;50(2):181-194. doi: 10.1007/s00134-023-07298-z. Epub 2024 Jan 18. Intensive Care Med. 2024. PMID: 38236292 Review.
Phase-3 trial of recombinant human alkaline phosphatase for patients with sepsis-associated acute kidney injury (REVIVAL).
Pickkers P, Angus DC, Bass K, Bellomo R, van den Berg E, Bernholz J, Bestle MH, Doi K, Doig CJ, Ferrer R, Francois B, Gammelager H, Pedersen UG, Hoste E, Iversen S, Joannidis M, Kellum JA, Liu K, Meersch M, Mehta R, Millington S, Murray PT, Nichol A, Ostermann M, Pettilä V, Solling C, Winkel M, Young PJ, Zarbock A; REVIVAL investigators. Pickkers P, et al. Among authors: angus dc. Intensive Care Med. 2024 Jan;50(1):68-78. doi: 10.1007/s00134-023-07271-w. Epub 2024 Jan 3. Intensive Care Med. 2024. PMID: 38172296 Free PMC article. Clinical Trial.
Prospective Assessment of Humoral and Cellular Immune Responses to a Third COVID-19 mRNA Vaccine Dose Among Immunocompromised Individuals.
Haidar G, Hodges JC, Bilderback A, Lukanski A, Linstrum K, Postol B, Troyan R, Wisniewski MK, Coughenour L, Heaps A, Jacobs JL, Hughes Kramer K, Klamar-Blain C, Kohl J, Liang W, Morris B, Macatangay BJC, Parikh UM, Sobolewksi MD, Musgrove C, Crandall MD, Mahon J, Mulvey K, Collins K, King AC, Wells A, Zapf R, Agha M, Minnier T, Angus DC, Mellors JW. Haidar G, et al. Among authors: angus dc. J Infect Dis. 2024 May 15;229(5):1328-1340. doi: 10.1093/infdis/jiad511. J Infect Dis. 2024. PMID: 37972260
Effect of Neutralizing Monoclonal Antibody Treatment on Early Trajectories of Virologic and Immunologic Biomarkers in Patients Hospitalized With COVID-19.
Jensen TO, Grandits GA, Jain MK, Murray TA, Grund B, Shaw-Saliba K, Matthay MA, Abassi M, Ardelt M, Baker JV, Chen P, Dewar RL, Goodman AL, Hatlen TJ, Highbarger HC, Holodniy M, Lallemand P, Laverdure S, Leshnower BG, Looney D, Moschopoulos CD, Mugerwa H, Murray DD, Mylonakis E, Nagy-Agren S, Rehman MT, Rupert A, Stevens RA, Turville S, Weintrob A, Wick K, Lundgren J, Ko ER; ACTIV-3/TICO Study Group. Jensen TO, et al. J Infect Dis. 2024 Mar 14;229(3):671-679. doi: 10.1093/infdis/jiad446. J Infect Dis. 2024. PMID: 37948759 Free PMC article. Clinical Trial.
Simvastatin in Critically Ill Patients with Covid-19.
REMAP-CAP Investigators; Hills TE, Lorenzi E, Berry LR, Shyamsundar M, Al-Beidh F, Annane D, Arabi Y, Aryal D, Au C, Beane A, Bhimani Z, Bonten M, Bradbury CA, Brunkhorst FM, Burrell A, Buxton M, Calfee CS, Cecconi M, Cheng AC, Cove ME, Detry MA, Estcourt LJ, Fitzgerald M, Goligher EC, Goossens H, Green C, Haniffa R, Harrison DA, Hashmi M, Higgins AM, Horvat C, Huang DT, Ichihara N, Jayakumar D, Kruger PS, Lamontagne F, Lampro L, Lawler PR, Marshall JC, Mason AJ, McGlothlin A, McGuinness S, McQuilten ZK, McVerry BJ, Mouncey PR, Murthy S, Neal MD, Nichol AD, O'Kane CM, Parke RL, Parker JC, Rabindrarajan E, Reyes LF, Rowan KM, Saito H, Santos M, Saunders CT, Seymour CW, Shankar-Hari M, Sinha P, Thompson BT, Turgeon AF, Turner AM, van de Veerdonk F, Weis S, Young IS, Zarychanski R, Lewis RJ, McArthur CJ, Angus DC, Berry SM, Derde LPG, Webb SA, Gordon AC, McAuley DF. REMAP-CAP Investigators, et al. Among authors: angus dc. N Engl J Med. 2023 Dec 21;389(25):2341-2354. doi: 10.1056/NEJMoa2309995. Epub 2023 Oct 25. N Engl J Med. 2023. PMID: 37888913 Free PMC article. Clinical Trial.
Intravenous Vitamin C for Patients Hospitalized With COVID-19: Two Harmonized Randomized Clinical Trials.
LOVIT-COVID Investigators, on behalf of the Canadian Critical Care Trials Group, and the REMAP-CAP Investigators; Adhikari NKJ, Hashmi M, Tirupakuzhi Vijayaraghavan BK, Haniffa R, Beane A, Webb SA, Angus DC, Gordon AC, Cook DJ, Guyatt GH, Berry LR, Lorenzi E, Mouncey PR, Au C, Pinto R, Ménard J, Sprague S, Masse MH, Huang DT, Heyland DK, Nichol AD, McArthur CJ, de Man A, Al-Beidh F, Annane D, Anstey M, Arabi YM, Battista MC, Berry S, Bhimani Z, Bonten MJM, Bradbury CA, Brant EB, Brunkhorst FM, Burrell A, Buxton M, Cecconi M, Cheng AC, Cohen D, Cove ME, Day AG, Derde LPG, Detry MA, Estcourt LJ, Fagbodun EO, Fitzgerald M, Goossens H, Green C, Higgins AM, Hills TE, Horvat C, Ichihara N, Jayakumar D, Kanji S, Khoso MN, Lawler PR, Lewis RJ, Litton E, Marshall JC, McAuley DF, McGlothlin A, McGuinness SP, McQuilten ZK, McVerry BJ, Murthy S, Parke RL, Parker JC, Reyes LF, Rowan KM, Saito H, Salahuddin N, Santos MS, Saunders CT, Seymour CW, Shankar-Hari M, Tolppa T, Trapani T, Turgeon AF, Turner AM, Udy AA, van de Veerdonk FL, Zarychanski R, Lamontagne F. LOVIT-COVID Investigators, on behalf of the Canadian Critical Care Trials Group, and the REMAP-CAP Investigators, et al. Among authors: angus dc. JAMA. 2023 Nov 14;330(18):1745-1759. doi: 10.1001/jama.2023.21407. JAMA. 2023. PMID: 37877585 Free PMC article.
Uncovering heterogeneity in sepsis: a comparative analysis of subphenotypes.
van Amstel RBE, Kennedy JN, Scicluna BP, Bos LDJ, Peters-Sengers H, Butler JM, Cano-Gamez E, Knight JC, Vlaar APJ, Cremer OL, Angus DC, van der Poll T, Seymour CW, van Vught LA; MARS Consortium. van Amstel RBE, et al. Among authors: angus dc. Intensive Care Med. 2023 Nov;49(11):1360-1369. doi: 10.1007/s00134-023-07239-w. Epub 2023 Oct 18. Intensive Care Med. 2023. PMID: 37851064 Free PMC article.
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