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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1946 1
1947 2
1948 2
1949 2
1950 3
1952 8
1953 11
1954 13
1955 21
1956 13
1957 16
1958 22
1959 11
1960 10
1961 22
1962 17
1963 56
1964 60
1965 47
1966 74
1967 114
1968 156
1969 148
1970 160
1971 145
1972 134
1973 60
1974 78
1975 154
1976 159
1977 182
1978 163
1979 153
1980 181
1981 195
1982 256
1983 311
1984 263
1985 329
1986 318
1987 309
1988 370
1989 433
1990 404
1991 438
1992 466
1993 436
1994 427
1995 471
1996 457
1997 543
1998 622
1999 616
2000 692
2001 741
2002 743
2003 774
2004 886
2005 1009
2006 1084
2007 1137
2008 1241
2009 1358
2010 1451
2011 1664
2012 1753
2013 1932
2014 2130
2015 2146
2016 2267
2017 2440
2018 2703
2019 2984
2020 3352
2021 3490
2022 3759
2023 3326
2024 3661
2025 276

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53,963 results

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Page 1
Timing of antibiotic therapy in the ICU.
Kollef MH, Shorr AF, Bassetti M, Timsit JF, Micek ST, Michelson AP, Garnacho-Montero J. Kollef MH, et al. Crit Care. 2021 Oct 15;25(1):360. doi: 10.1186/s13054-021-03787-z. Crit Care. 2021. PMID: 34654462 Free PMC article. Review.
Thus not only is early empiric antibiotic administration important but the selection of those agents is crucial as well. ...Such advances should help identify patients needing empiric antibiotic therapy at an earlier time point as well as the specific anti …
Thus not only is early empiric antibiotic administration important but the selection of those agents is crucial as well. ...Su …
Choosing antibiotic therapy for severe community-acquired pneumonia.
Martin-Loeches I, Garduno A, Povoa P, Nseir S. Martin-Loeches I, et al. Curr Opin Infect Dis. 2022 Apr 1;35(2):133-139. doi: 10.1097/QCO.0000000000000819. Curr Opin Infect Dis. 2022. PMID: 35190510 Review.
The aim of this review is to further report on the major advances in treatment for patients with sCAP including new antibiotic treatments despite macrolide resistance as seen in the ICU, and multifaceted antibiotic stewardship interventions that may lead to the redu …
The aim of this review is to further report on the major advances in treatment for patients with sCAP including new antibiotic treatm …
History of Antibiotics Research.
Mohr KI. Mohr KI. Curr Top Microbiol Immunol. 2016;398:237-272. doi: 10.1007/82_2016_499. Curr Top Microbiol Immunol. 2016. PMID: 27738915 Review.
The emphasis of this chapter is to give an overview of the history of antibiotics research. The situation within the pre-antibiotic era as well as in the early antibiotic era will be described until the Golden Age of Antibiotics will conclude this time …
The emphasis of this chapter is to give an overview of the history of antibiotics research. The situation within the pre-antibioti …
Comprehensive Guidance for Antibiotic Dosing in Obese Adults.
Meng L, Mui E, Holubar MK, Deresinski SC. Meng L, et al. Pharmacotherapy. 2017 Nov;37(11):1415-1431. doi: 10.1002/phar.2023. Epub 2017 Oct 30. Pharmacotherapy. 2017. PMID: 28869666 Review.
Additional studies are needed to better understand and resolve discrepant published results regarding the PK of antibiotics to establish optimal dosing strategies in obese adults. Alternative dosing strategies, such as extended infusions, should be considered for time-depe …
Additional studies are needed to better understand and resolve discrepant published results regarding the PK of antibiotics to establ …
Minocycline and Doxycycline: More Than Antibiotics.
Singh S, Khanna D, Kalra S. Singh S, et al. Curr Mol Pharmacol. 2021;14(6):1046-1065. doi: 10.2174/1874467214666210210122628. Curr Mol Pharmacol. 2021. PMID: 33568043 Review.
The objective of the current review is to provide clinical and preclinical, non-antibiotic uses of minocycline as well as doxycycline. Relevant literature covers antibiotic actions but is more specifically concerned with the non-antibiotic biological aspect o …
The objective of the current review is to provide clinical and preclinical, non-antibiotic uses of minocycline as well as doxycycline …
The past, present, and future of antibiotics.
Cook MA, Wright GD. Cook MA, et al. Sci Transl Med. 2022 Aug 10;14(657):eabo7793. doi: 10.1126/scitranslmed.abo7793. Epub 2022 Aug 10. Sci Transl Med. 2022. PMID: 35947678 Review.
Antibiotics have transformed modern medicine. They are essential for treating infectious diseases and enable vital therapies and procedures. ...This will require substantial changes in policy, quantitative understanding of the societal value of these drugs, and investment …
Antibiotics have transformed modern medicine. They are essential for treating infectious diseases and enable vital therapies and proc …
The macrolide antibiotic renaissance.
Dinos GP. Dinos GP. Br J Pharmacol. 2017 Sep;174(18):2967-2983. doi: 10.1111/bph.13936. Epub 2017 Aug 10. Br J Pharmacol. 2017. PMID: 28664582 Free PMC article. Review.
Subsequently, in order to address increasing antibiotic resistance, a third generation of macrolides displaying improved activity against many macrolide resistant strains was developed. ...In contrast, a recent published breakthrough introduced a new chemical platform for …
Subsequently, in order to address increasing antibiotic resistance, a third generation of macrolides displaying improved activity aga …
Microbial spectrum and antibiotic sensitivity in infantile dacryocystitis.
Qing H, Yang Z, Shi M, Zhang J, Sun S, Han L. Qing H, et al. Graefes Arch Clin Exp Ophthalmol. 2021 May;259(5):1263-1272. doi: 10.1007/s00417-020-05026-7. Epub 2021 Jan 8. Graefes Arch Clin Exp Ophthalmol. 2021. PMID: 33417095
PURPOSE: To identify the characteristics and the spectrum of microbial agents of infantile dacryocystitis and to assess the trends in both antibiotic sensitivities and pathogens over the past 10 years. ...Patient demographics, microbial analysis, and suscepti …
PURPOSE: To identify the characteristics and the spectrum of microbial agents of infantile dacryocystitis and to assess the tr …
Broad spectrum antibiotic stewardship by quality improvement methods.
Niazi-Ali S, Bircher J. Niazi-Ali S, et al. Int J Risk Saf Med. 2022;33(S1):S35-S40. doi: 10.3233/JRS-227021. Int J Risk Saf Med. 2022. PMID: 35871365 Free PMC article.
OBJECTIVE: Broad spectrum antibiotic prescribing is often seen as a proxy marker of increasing resistance within a population and so it is important that they are used sparingly, to avoid drug-resistant bacteria developing. ...RESULTS: A 10.6% reduction of broad …
OBJECTIVE: Broad spectrum antibiotic prescribing is often seen as a proxy marker of increasing resistance within a population …
Antibiotics and Bacterial Resistance-A Short Story of an Endless Arms Race.
Baran A, Kwiatkowska A, Potocki L. Baran A, et al. Int J Mol Sci. 2023 Mar 17;24(6):5777. doi: 10.3390/ijms24065777. Int J Mol Sci. 2023. PMID: 36982857 Free PMC article. Review.
In addition to intrinsic resistance, bacteria can acquire resistance to particular antimicrobial agents through the transfer of genetic material conferring resistance. Amongst the most common bacterial resistance strategies are: drug target site changes, increased cell wal …
In addition to intrinsic resistance, bacteria can acquire resistance to particular antimicrobial agents through the transfer of genet …
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