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Page 1
A proteomic profile correlates with salivary gland inflammation and disease-associated antibodies in Sjogren's disease.
Björk A, Mofors J, Meneghel L, Kvarnström M, Maeland E, Richardsdotter Andersson E, Jonsson R, Omdal R, Forsblad-d'Elia H, Magnusson Bucher S, Eriksson P, Mandl T, Olsson P, Fischer M, Norheim KB, Auglænd Johnsen SJ, Hammenfors D, Skarstein K, Jonsson MV, Appel S, Kockum I, Imgenberg-Kreuz J, Nordmark G, Wahren-Herlenius M. Björk A, et al. Ann Rheum Dis. 2026 Feb;85(2):339-350. doi: 10.1016/j.ard.2025.11.013. Epub 2025 Dec 12. Ann Rheum Dis. 2026. PMID: 41387154 Free article.
Patients were stratified by antinuclear antibodies (ANA), anti-Ro/SSA, anti-La/SSB autoantibodies, and extraglandular manifestations. ...CONCLUSIONS: We define a validated serum proteomic signature that reflects local glandular inflammation and correlates wit …
Patients were stratified by antinuclear antibodies (ANA), anti-Ro/SSA, anti-La/SSB autoantibodies, and extraglandular manifest …
Antinuclear Antibodies in Polycystic Ovary Syndrome: A Systematic Review of Observational Studies.
Kwiatkowski J, Akpang N, Zaborowska L, Ludwin A. Kwiatkowski J, et al. Int J Mol Sci. 2025 Sep 28;26(19):9493. doi: 10.3390/ijms26199493. Int J Mol Sci. 2025. PMID: 41096756 Free PMC article.
It is also associated with insulin resistance, chronic inflammation, and oxidative stress, all of which may promote autoimmunity. Several studies have suggested a higher occurrence of antinuclear antibodies (ANA) in PCOS but the main challenge in this field i …
It is also associated with insulin resistance, chronic inflammation, and oxidative stress, all of which may promote autoimmunity. Sev …
Roth Spots.
Gurnani B, Tivakaran VS. Gurnani B, et al. 2025 Dec 1. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan–. 2025 Dec 1. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan–. PMID: 29494053 Free Books & Documents.
In metabolic or autoimmune disorders, evaluation should include fasting glucose, renal function tests, and serologic markers such as antinuclear antibody, anti-double-stranded DNA, antineutrophil cytoplasmic antibody (ANCA), and antiphospholipid antibodies. ...The p …
In metabolic or autoimmune disorders, evaluation should include fasting glucose, renal function tests, and serologic markers such as anti …
Clinical Significance of Antinuclear Antibodies in Patients with Rheumatoid Arthritis: From SETOUCHI-RA Registry.
Nakano K, Fujita S, Hiramatsu-Asano S, Nagasu A, Tsuji S, Koide Y, Yamada M, Mizuta Y, Ikeda M, Hirano H, Morita Y. Nakano K, et al. J Clin Med. 2025 Feb 26;14(5):1553. doi: 10.3390/jcm14051553. J Clin Med. 2025. PMID: 40095466 Free PMC article.
Background/Objectives: Rheumatoid arthritis (RA) is a representative systemic autoimmune rheumatic disease (SARD) characterized by synovial inflammation. While antinuclear antibodies (ANAs) positivity in patients with RA varies widely, the relationship betwee …
Background/Objectives: Rheumatoid arthritis (RA) is a representative systemic autoimmune rheumatic disease (SARD) characterized by synovial …
Prevalence and association testing of antinuclear antibodies and inflammatory bowel disease in Taiwan.
Yang TM, Lu FT, Yen HH, Chen YY. Yang TM, et al. PeerJ. 2025 Nov 28;13:e20474. doi: 10.7717/peerj.20474. eCollection 2025. PeerJ. 2025. PMID: 41333288 Free PMC article.
BACKGROUND: Inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), are characterized by chronic inflammation of the gastrointestinal tract. Antinuclear antibodies (ANAs), which are autoantibodies directed against nuclear …
BACKGROUND: Inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), are characterized by chronic in …
Autoantibodies in systemic sclerosis: From disease bystanders to pathogenic players.
Chepy A, Collet A, Launay D, Dubucquoi S, Sobanski V. Chepy A, et al. J Transl Autoimmun. 2025 Jan 21;10:100272. doi: 10.1016/j.jtauto.2025.100272. eCollection 2025 Jun. J Transl Autoimmun. 2025. PMID: 39917316 Free PMC article. Review.
This narrative review uses systemic sclerosis (SSc) as an example to highlight the importance of Aab associated with HEp-2 immunofluorescence assay positivity (traditionally referred as antinuclear antibodies [ANA]), exploring recent developments in the field. First …
This narrative review uses systemic sclerosis (SSc) as an example to highlight the importance of Aab associated with HEp-2 immunofluorescenc …
Clinical significance of anti-mitochondrial antibodies and PBC-specific anti-nuclear antibodies in evaluating atypical primary biliary cholangitis with normal alkaline phosphatase levels.
Li S, Zhang K, Liu H, Chen M, Wang J, Yang Y, Gong Y, Liu X, Yang Y. Li S, et al. Clin Chem Lab Med. 2025 Aug 20;63(12):2501-2512. doi: 10.1515/cclm-2025-0357. Print 2025 Nov 25. Clin Chem Lab Med. 2025. PMID: 40829001 Free article.
OBJECTIVES: The clinical implications of positive anti-mitochondrial antibodies (AMAs) and/or primary biliary cholangitis (PBC)-specific anti-nuclear antibodies (ANAs) in patients with normal alkaline phosphatase (ALP) remain uncertain. ...CONCLUSIONS: Over 50 % of …
OBJECTIVES: The clinical implications of positive anti-mitochondrial antibodies (AMAs) and/or primary biliary cholangitis (PBC)-speci …
Prevalence of Antinuclear Antibodies in Patients With Coronary Artery Disease: A Scoping Review.
Antony M, Thymalil C, Nagy S, Amini K, Kesselman MM. Antony M, et al. Cureus. 2025 Feb 12;17(2):e78915. doi: 10.7759/cureus.78915. eCollection 2025 Feb. Cureus. 2025. PMID: 40091923 Free PMC article. Review.
Antinuclear-antibody (ANA) is an immunoglobulin that attacks nuclear and cytoplasmic components within cells, serving as a biomarker for many autoimmune conditions. ...The search terms "Coronary artery disease" OR "Coronary disease" OR "Coronary aneurysm" AND "Antibodie …
Antinuclear-antibody (ANA) is an immunoglobulin that attacks nuclear and cytoplasmic components within cells, serving as a biomarker …
Autoimmune antibodies and systemic inflammatory markers are prevalent and associated with cognition in individuals aged 90.
Farahmand G, Leiby AC, Yu J, Ramanathan A, Javaheri R, Kawas CH, Woodworth DC, Corrada MM, Qian T, Ahmad Sajjadi S. Farahmand G, et al. J Alzheimers Dis. 2025 Oct;107(3):1217-1225. doi: 10.1177/13872877251365560. Epub 2025 Aug 8. J Alzheimers Dis. 2025. PMID: 40776635 Free PMC article.
For measures of autoimmunity, we evaluated antinuclear, antineutrophil cytoplasmic (ANCA), rheumatoid factor, double stranded DNA, antithyroglobulin, and thyroid peroxidase antibodies. ...To examine the relationship between autoimmune antibodies and inflammat …
For measures of autoimmunity, we evaluated antinuclear, antineutrophil cytoplasmic (ANCA), rheumatoid factor, double stranded DNA, an …
Comparative single-cell and spatial profiling of anti-SSA-positive and anti-centromere-positive Sjogren's disease reveals common and distinct immune activation and fibroblast-mediated inflammation.
Inamo J, Takeshita M, Suzuki K, Tsunoda K, Usuda S, Kuramoto J, Moody J, Hon CC, Ando Y, Sasaki T, Yoshitake K, Mitsuyama S, Asakawa S, Kanai Y, Takeuchi T, Kaneko Y. Inamo J, et al. Nat Commun. 2025 Sep 22;16(1):8299. doi: 10.1038/s41467-025-63935-9. Nat Commun. 2025. PMID: 40983612 Free PMC article.
Furthermore, spatial profiling reveals THY1(+) fibroblasts, expressing complement genes and chemokines, as key hubs orchestrating inflammation within the salivary glands. These findings deepen our understanding of the pathogenesis of SjD, and may inform the development of …
Furthermore, spatial profiling reveals THY1(+) fibroblasts, expressing complement genes and chemokines, as key hubs orchestrating inflamm …
Immunological Markers Associated with Skin Manifestations of EGPA.
Brunetto S, Buta F, Gangemi S, Ricciardi L. Brunetto S, et al. Int J Mol Sci. 2025 Aug 2;26(15):7472. doi: 10.3390/ijms26157472. Int J Mol Sci. 2025. PMID: 40806600 Free PMC article.
Eosinophilic Granulomatosis with Polyangiitis (EGPA) is a rare systemic vasculitis with eosinophilic inflammation and variable clinical presentations. Although skin manifestations are frequent, current classification criteria do not include them, which may underestimate th …
Eosinophilic Granulomatosis with Polyangiitis (EGPA) is a rare systemic vasculitis with eosinophilic inflammation and variable clinic …
Molecular Insights into Elevated Autoantibodies in Polycystic Ovary Syndrome: Mechanisms and Clinical Implications.
Kwiatkowski J, Akpang N, Ziemkiewicz Z, Zaborowska L, Ludwin A. Kwiatkowski J, et al. Int J Mol Sci. 2025 Aug 23;26(17):8192. doi: 10.3390/ijms26178192. Int J Mol Sci. 2025. PMID: 40943118 Free PMC article. Review.
Furthermore, an elevated prevalence of diverse autoantibodies is observed in women diagnosed with PCOS. These include antibodies specific to autoimmune diseases, e.g., anti-thyroid peroxidase (anti-TPO), anti-thyroglobulin (anti-TG), and antinuclear antibodies …
Furthermore, an elevated prevalence of diverse autoantibodies is observed in women diagnosed with PCOS. These include antibodies spec …
SLE classification criteria item relationships: implications on SLE as a disease entity.
Aringer M, Szelinski F, Dörner T, Costenbader KH, Johnson SR. Aringer M, et al. Ann Rheum Dis. 2025 Nov;84(11):1801-1810. doi: 10.1016/j.ard.2025.07.024. Epub 2025 Aug 22. Ann Rheum Dis. 2025. PMID: 40849272 Free article.
Relevant correlations between items were found within the domains, but some associations between items of different domains still showed significant, if mostly weak associations with r values of 0.10 to 0.26. These included correlations between antibodies to double-strande …
Relevant correlations between items were found within the domains, but some associations between items of different domains still showed sig …
Autoantibodies are associated with worse outcomes in MASLD.
Soria A, Díaz A, Iruzubieta P, Martín-Mateos R, Salcedo-Allende MT, Jiménez-Masip A, Fuster-Anglada C, Arias-Loste MT, Perna C, El Maimouni C, Pericas JM, Ferrer-Gómez A, González CJ, Muñoz-Martínez S, Padilla M, Crespo J, Calixto Z, Sabiote C, Albillos A, Cervera M, Olivas I, Arvaniti P, Hernández-Évole H, Jiménez-Esquivel N, Gratacós-Ginès J, Juanola A, Pose E, Coll M, Nadal R, Pérez-Guasch M, Fabrellas N, Ginès P, Londoño MC, Graupera I. Soria A, et al. JHEP Rep. 2025 May 31;7(10):101470. doi: 10.1016/j.jhepr.2025.101470. eCollection 2025 Oct. JHEP Rep. 2025. PMID: 40980159 Free PMC article.
BACKGROUND & AIMS: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a leading cause of chronic liver disease worldwide. Autoantibodies (Ab), such as antinuclear antibodies (ANA) and anti-smooth muscle antibodies (ASMA), are frequently d …
BACKGROUND & AIMS: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a leading cause of chronic liver disease worldwid …
Clinical and pathological features of antinuclear antibody-positive drug-induced liver injury compared with autoimmune hepatitis: A retrospective study.
Liu W, Zhang Z, Ma X, Zeng X, Yuan S, Li X, Nie F, Yang L. Liu W, et al. Medicine (Baltimore). 2025 Nov 21;104(47):e45750. doi: 10.1097/MD.0000000000045750. Medicine (Baltimore). 2025. PMID: 41305710 Free PMC article.
We observed that the detection rate of antinuclear antibodies was significantly higher in female patients. Compared to the AIH group, the ANA-positive DILI group exhibited lower levels of the S index, serum globulin, activated partial thromboplastin time, immunoglob …
We observed that the detection rate of antinuclear antibodies was significantly higher in female patients. Compared to the AIH …
Impact of Concordance Between Antinuclear Antibody Indirect Immunofluorescence Patterns and Myositis Antibodies in Idiopathic Inflammatory Myopathies: Study Protocol.
Pinto Oliveira C, Pereira Silva M, Vilafanha C, Costa G, Santos ME, Gonçalves MJ, Silva P, Fernandes V, Meirinhos T, Almeida C, Prata AR, Barcelos A, Campanilho-Marques R, Dourado E. Pinto Oliveira C, et al. Acta Med Port. 2025 Nov 3;38(11):718-723. doi: 10.20344/amp.23542. Epub 2025 Nov 3. Acta Med Port. 2025. PMID: 41204860 Free article.
Patients with IIM may be positive for myositis antibodies (MAs), including myositis-specific and/or associated antibodies. Although helpful for establishing the diagnosis of IIM in the appropriate clinical setting, the presence of MAs does not always predict the occ …
Patients with IIM may be positive for myositis antibodies (MAs), including myositis-specific and/or associated antibodies. Alt …
French protocol for the diagnosis and management of juvenile idiopathic arthritis including pediatric-onset Still's disease.
Quartier P, Belot A, Breton S, Carbasse A, Devauchelle V, Fautrel B, Georgin-Lavialle S, Jurquet AL, Koné-Paut I, Lemelle I, Meinzer U, Melki I, Pillet P, Reumaux H, Rossi-Semerano L, Uettwiller F; Collaborators. Quartier P, et al. Rev Med Interne. 2025 Aug;46(8):449-481. doi: 10.1016/j.revmed.2025.06.001. Epub 2025 Jun 20. Rev Med Interne. 2025. PMID: 40544011 Free article.
A new classification divides JIA into 5 groups: the systemic form, early-onset oligo- and polyarthritis with anti-nuclear antibodies (associated with a risk of chronic anterior uveitis), polyarthritis with rheumatoid factor, juvenile spondyloarthropathy and non-groupable f …
A new classification divides JIA into 5 groups: the systemic form, early-onset oligo- and polyarthritis with anti-nuclear antibodies …
Social anxiety disorder and antibodies against glial cells in the cerebrospinal fluid.
Weiser J, Rau A, von Zedtwitz K, Feige B, Nickel K, Maier SJ, Dressle RJ, Venhoff N, van Elst LT, Schiele MA, Domschke K, Prüss H, Endres D. Weiser J, et al. Brain Behav Immun Health. 2025 Jul 19;48:101064. doi: 10.1016/j.bbih.2025.101064. eCollection 2025 Oct. Brain Behav Immun Health. 2025. PMID: 40746968 Free PMC article.
Testing for all known characterized neuronal and glial IgG antibodies identified slightly positive ("+") recoverin IgG antibodies only in the serum (using an immunoassay). ...The testing for all characterized neuronal/glial antibodies showed only weakly posit …
Testing for all known characterized neuronal and glial IgG antibodies identified slightly positive ("+") recoverin IgG antibodies …
Severe Systemic Lupus Erythematosus with Anti-centromere Antibody.
Fujii W, Seno T, Kohno M, Omatsu I, Konishi E, Mihara Y, Kawahito Y. Fujii W, et al. Intern Med. 2025 Sep 15;64(18):2790-2793. doi: 10.2169/internalmedicine.4951-24. Epub 2025 Feb 22. Intern Med. 2025. PMID: 39993749 Free PMC article.
The diagnosis was performed using the international classification criteria updated in 2019. The significance of anti-nuclear antibodies (ANAs) with a centromere pattern has not been clearly documented in these criteria. We herein report a patient with ANAs with a centrome …
The diagnosis was performed using the international classification criteria updated in 2019. The significance of anti-nuclear antibodies …
Immunoglobulins G from Patients with Systemic Sclerosis Modify the Molecular Signatures of Endothelial Cells.
Chepy A, Vivier S, Bray F, Chauvet C, Lescoat A, Elhannani A, Figeac M, Guilbert L, Leprêtre F, Bourel L, Hachulla E, Rolando C, Lecureur V, Dubucquoi S, Launay D, Sobanski V. Chepy A, et al. RMD Open. 2025 Mar 23;11(1):e004290. doi: 10.1136/rmdopen-2024-004290. RMD Open. 2025. PMID: 40122572 Free PMC article.
OBJECTIVE: Antinuclear antibodies (ANA) are powerful biomarkers in systemic sclerosis (SSc). Functional antibodies (FA) might be implicated in vasculopathy, in which endothelial cells (EC) are key players. ...
OBJECTIVE: Antinuclear antibodies (ANA) are powerful biomarkers in systemic sclerosis (SSc). Functional antibodies (FA) …
Literature review and case study of predominant tubulointerstitial lupus nephritis.
Wang J, Zuo Y, Liu C, Ke M, Tang Y, Liu L. Wang J, et al. Ren Fail. 2025 Dec;47(1):2558089. doi: 10.1080/0886022X.2025.2558089. Epub 2025 Sep 18. Ren Fail. 2025. PMID: 40963504 Free PMC article. Review.
The diagnosis of SLE was confirmed on the basis of proteinuria, positive antinuclear antibodies, and immunological and haematological disorders. Renal biopsy revealed severe chronic tubulointerstitial nephritis with excessive immune complex deposition in the tubular …
The diagnosis of SLE was confirmed on the basis of proteinuria, positive antinuclear antibodies, and immunological and haemato …
Breast Implant Illness: Symptoms, Outcomes with Explantation and Potential Etiologies-A Systematic Review and Meta-analysis.
Ferreira S, Barros AS, Marques M. Ferreira S, et al. Aesthetic Plast Surg. 2025 Dec;49(23):6600-6620. doi: 10.1007/s00266-025-05142-x. Epub 2025 Aug 11. Aesthetic Plast Surg. 2025. PMID: 40788544 Free PMC article.
Meta-analyses were performed on symptom reduction, fibromyalgia and antinuclear antibodies (ANA) positivity prevalence. RESULTS: From 4612 identified articles, 33 met the inclusion criteria, encompassing 6048 women with an average age of 46.0 years. ...ANA positivit …
Meta-analyses were performed on symptom reduction, fibromyalgia and antinuclear antibodies (ANA) positivity prevalence. RESULT …
Demographic Characteristics and Inflammatory Biomarker Profile in Psoriatic Arthritis Patients with Comorbid Fibromyalgia: A Cross-Sectional Study.
Paroli M, Gioia C, Accapezzato D, Caccavale R. Paroli M, et al. Medicina (Kaunas). 2025 Jun 6;61(6):1050. doi: 10.3390/medicina61061050. Medicina (Kaunas). 2025. PMID: 40572738 Free PMC article.
To investigate the contribution of demographic factors and available serum biomarkers of inflammation and autoimmunity in characterizing the heterogeneity among patients meeting the classification criteria for both PsA and FM. ...Demographic data, serum inflammatory marker …
To investigate the contribution of demographic factors and available serum biomarkers of inflammation and autoimmunity in characteriz …
Drug-Induced Renal Vasculitis: Etiology, Pathogenesis, Clinical Manifestations, and Therapeutic Approaches-A Narrative Review.
Mohamed Siraj H, Ali M, Sharma SS, Begum A, Ahmad MH, Muhammad H, Aref Elsayed RKMK, Tahir MH. Mohamed Siraj H, et al. Health Sci Rep. 2025 Apr 16;8(4):e70667. doi: 10.1002/hsr2.70667. eCollection 2025 Apr. Health Sci Rep. 2025. PMID: 40242254 Free PMC article.
BACKGROUND AND AIMS: Drug-induced renal vasculitis arises from various medications that cause immunological dysregulation or direct vascular damage, leading to inflammation and thrombosis. Clinical manifestations vary widely, from mild constitutional symptoms to severe org …
BACKGROUND AND AIMS: Drug-induced renal vasculitis arises from various medications that cause immunological dysregulation or direct vascular …
Ultrasensitive quantification of serum IFN-α and IFN-γ in systemic lupus erythematosus: A cross-sectional observational study.
González-Gay MÁ, Gómez-Bernal F, Quevedo-Abeledo JC, Almeida-Santiago C, Heras-Recuero E, Torres-Roselló A, de Vera-González A, Tejera-Segura B, García-Barrera E, Blázquez-Sánchez T, Villar LM, Ocejo-Vinyals JG, Largo R, Ferraz-Amaro I. González-Gay MÁ, et al. PLoS Med. 2025 Dec 5;22(12):e1004841. doi: 10.1371/journal.pmed.1004841. eCollection 2025 Dec. PLoS Med. 2025. PMID: 41348830 Free PMC article.
After multivariable adjustment, IFN-alpha-but not IFN-gamma-was significantly and positively associated with acute-phase reactants (C-reactive protein and interleukin-6), disease activity indices (SLEDAI-2K, beta coefficient: 0.20 [95% confidence interval 0.09, 0.32] log pg/ml, p …
After multivariable adjustment, IFN-alpha-but not IFN-gamma-was significantly and positively associated with acute-phase reactants (C-reacti …
Effect of Age on Xenobiotic-Induced Autoimmunity.
de Ocampo C, Peiss AK, Leung HY, Janssen LM, Kono DH, Mayeux JM, Pollard KM. de Ocampo C, et al. bioRxiv [Preprint]. 2025 May 27:2025.05.22.655368. doi: 10.1101/2025.05.22.655368. bioRxiv. 2025. PMID: 40502004 Free PMC article. Preprint.
Aging is associated with increased spontaneous autoantibody production and chronic inflammation, yet its impact on xenobiotic-induced autoimmunity remains unexplored. This study investigates the effect of age on mercury-induced autoimmunity (HgIA) in B10.S mice, a model of …
Aging is associated with increased spontaneous autoantibody production and chronic inflammation, yet its impact on xenobiotic-induced …
Comparison of pathological features of patients with antibody-negative and positive primary biliary cholangitis.
Liu HL, Liu X, Hu YF, Wang XX, Zhang Y, Wang L, Li SS, Bao YJ, Zheng SW, Xiong QF, Zhong YD, Liu DX, Huang P, Feng XN, Zeng WQ, Zhang CY, Zhang K, Yang YF. Liu HL, et al. BMC Gastroenterol. 2025 Sep 29;25(1):667. doi: 10.1186/s12876-025-04280-5. BMC Gastroenterol. 2025. PMID: 41023613 Free PMC article.
OBJECTIVE: To examine the differences and similarities among primary biliary cholangitis (PBC) with positive and negative expression of autoantibodies (anti-mitochondrial antibodies AMA and AMA-M2, antinuclear antibodies anti-gp210, and anti-sp100). METHODS: …
OBJECTIVE: To examine the differences and similarities among primary biliary cholangitis (PBC) with positive and negative expression of auto …
Application of machine learning in assessing disease activity in SLE.
Wang Y, Yuan P, Wei W, Chen R, Wang T, Ouyang R, Wang F, Hou H, Wu S. Wang Y, et al. Lupus Sci Med. 2025 Apr 8;12(1):e001456. doi: 10.1136/lupus-2024-001456. Lupus Sci Med. 2025. PMID: 40204296 Free PMC article.
OBJECTIVE: SLE is a chronic autoimmune disease with immune complex deposition in various organs, causing inflammation. The Systemic Lupus Erythematosus Disease Activity Index 2000 assesses disease severity but is subjective. ...
OBJECTIVE: SLE is a chronic autoimmune disease with immune complex deposition in various organs, causing inflammation. The Systemic L …
A high polygenic risk score is associated with SSA/SSB antibody positivity and early onset in primary Sjögren's disease.
Fugmann C, Reid S, Pucholt P, Kvarnström M, Björk A, Mofors J, Sjöwall C, Eriksson P, Olsson P, Mandl T, Forsblad-d'Elia H, Magnusson Bucher S, Johnsen SJ, Norheim KB, Appel S, Hammenfors D, Jensen JL, Palm Ø, Omdal R, Jonsson R, Baecklund E, Wahren-Herlenius M, Leonard D, Imgenberg-Kreuz J, Nordmark G. Fugmann C, et al. Rheumatology (Oxford). 2025 Jul 1;64(7):4341-4346. doi: 10.1093/rheumatology/keae693. Rheumatology (Oxford). 2025. PMID: 39693120 Free PMC article.
OBJECTIVES: To calculate a polygenic risk score (PRS) based on single nucleotide variants (SNVs) previously associated with primary Sjogren's disease (SjD) with genome-wide significance and determine the genetic risk for SjD stratified by antibodies, sex and age at diagnos …
OBJECTIVES: To calculate a polygenic risk score (PRS) based on single nucleotide variants (SNVs) previously associated with primary Sjogren' …
Clinical impact of anti-SSA antigenic specificity on disease activity and patient-reported outcomes in primary Sjögren's disease: a real-life cohort study.
Fonzetti S, La Rocca G, Fulvio G, Dei B, Porciani C, Ferro F, Migliorini P, Mosca M, Baldini C. Fonzetti S, et al. Clin Exp Rheumatol. 2025 Dec;43(12):2209-2216. doi: 10.55563/clinexprheumatol/t01mio. Epub 2025 Dec 18. Clin Exp Rheumatol. 2025. PMID: 41410582 Free article.
OBJECTIVES: Anti-Ro/SSA antibodies are a hallmark of Sjogren's disease (SjD), yet the clinical implications of distinct antigenic targets remain insufficiently defined. ...In contrast, isolated anti-Ro60 patients showed the mildest systemic activity (ESSDAI 0 [0-0]) yet th …
OBJECTIVES: Anti-Ro/SSA antibodies are a hallmark of Sjogren's disease (SjD), yet the clinical implications of distinct antigenic tar …
Plasma interferon-alpha protein levels during pregnancy are associated with lower birth weight in systemic lupus erythematosus.
Stockfelt M, Torell A, Gunnarsson I, Svenungsson E, Zickert A, Sennström MM, Trysberg E, Bengtsson AA, Jönsen A, Strevens H, Sjöwall C, Saleh M, Pihl S, Leonard D, Rönnblom L, Akhter T, Blennow K, Zetterberg H, Jacobsson B, Lundell AC, Rudin A. Stockfelt M, et al. Rheumatology (Oxford). 2025 Mar 1;64(3):1469-1475. doi: 10.1093/rheumatology/keae332. Rheumatology (Oxford). 2025. PMID: 38876981 Free PMC article.
Protein levels of IFN-alpha were quantified in plasma collected in the second and third trimester with single-molecule array. Positivity for ANA and aPL antibodies was assessed during late pregnancy with multiplexed bead assay. Clinical outcomes included the adverse pregna …
Protein levels of IFN-alpha were quantified in plasma collected in the second and third trimester with single-molecule array. Positivity for …
Concomitant autoimmunity and late cancers in adult-onset immunodeficiency due to neutralizing anti-IFN-γ autoantibodies.
Tsai WT, Cheng CY, Sun HY, Guo BC, Chiang YC, Cheng CF, Pan YH, Wu UI, Wang JT, Sheng WH, Cheng A, Chen YC, Chang SC. Tsai WT, et al. Front Immunol. 2025 Apr 17;16:1526439. doi: 10.3389/fimmu.2025.1526439. eCollection 2025. Front Immunol. 2025. PMID: 40313931 Free PMC article.
Most patients had decreasing nAIGA titers over time; two outliers with persistently high neutralizing antibodies developed late-onset malignancies. CONCLUSION: Adult-onset immunodeficiency due to nAIGA is a syndrome associated with concomitant autoimmunity. Chronic infecti …
Most patients had decreasing nAIGA titers over time; two outliers with persistently high neutralizing antibodies developed late-onset …
Mediterranean fever gene variants may prevent the development of lupus nephritis in Japanese patients with systemic lupus erythematosus.
Endo Y, Koga T, Mohamed L, Tsuji Y, Umeda M, Hayashi H, Kishino T, Kawakami A. Endo Y, et al. Front Immunol. 2025 Jul 7;16:1571208. doi: 10.3389/fimmu.2025.1571208. eCollection 2025. Front Immunol. 2025. PMID: 40692783 Free PMC article.
BACKGROUND: Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by loss of immune tolerance, leading to systemic inflammation and organ damage. The Mediterranean fever (MEFV) gene, primarily linked to familial Mediterranean fever (FMF), has been sugge …
BACKGROUND: Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by loss of immune tolerance, leading to systemic in …
Alternation of anti-NMDA receptor subunit GluN2 antibody in a patient with SLE who promptly developed anxiety after belimumab.
Arinuma Y, Hasegawa Y, Oku K, Yamaoka K. Arinuma Y, et al. Immunol Med. 2025 Dec;48(4):397-399. doi: 10.1080/25785826.2025.2515331. Epub 2025 Jun 2. Immunol Med. 2025. PMID: 40455606 Free article.
She was diagnosed as SLE due to fever, general fatigue, polyarthritis, hypocomplementemia, and positivity of antinuclear antibody and anti-dsDNA antibody, and hydroxychloroquine (HCQ) monotherapy was initiated. ...Our case indicate that BEL may involve paradoxical elevatio …
She was diagnosed as SLE due to fever, general fatigue, polyarthritis, hypocomplementemia, and positivity of antinuclear antibody and …
Differences in IgG Sialylation Distinguish Asymptomatic From Symptomatic Antinuclear Antibody-Positive Individuals.
Muñoz-Grajales C, Ucciferri CC, Johnson SR, Touma Z, Ahmad Z, Bonilla D, Hiraki LT, Bookman A, Wither JE. Muñoz-Grajales C, et al. Arthritis Rheumatol. 2026 Jan;78(1):243-254. doi: 10.1002/art.43323. Epub 2025 Nov 11. Arthritis Rheumatol. 2026. PMID: 40693400 Free PMC article.
OBJECTIVE: The transition from asymptomatic antinuclear antibody (ANA) positivity to systemic autoimmune rheumatic disease (SARD) is associated with increased production of proinflammatory factors such as tumor necrosis factor alpha (TNFalpha). Here we investigate whether …
OBJECTIVE: The transition from asymptomatic antinuclear antibody (ANA) positivity to systemic autoimmune rheumatic disease (SARD) is …
An Unusual Gastrointestinal Presentation of Sjogren's Syndrome: A Case Report.
Sahwan O, Jamal F, Elshaer A, Batha L, Shahin T, Pham MM. Sahwan O, et al. Clin Case Rep. 2025 Oct 22;13(10):e71112. doi: 10.1002/ccr3.71112. eCollection 2025 Oct. Clin Case Rep. 2025. PMID: 41142224 Free PMC article.
This patient was diagnosed with SS in 2018 with positive antinuclear antibodies (ANA), rheumatoid factor (RF), SSA antibodies, and salivary lip gland biopsy. ...PET-CT scan did not show lymphadenopathy or significant inflammation. Full biopsy for defin …
This patient was diagnosed with SS in 2018 with positive antinuclear antibodies (ANA), rheumatoid factor (RF), SSA antibodi …
Anabolic-Androgenic Steroid-Induced Pneumonitis and Myocardial Injury in A Young Bodybuilder.
Chaghiashvili N, Potskverashvili N, Chaprava T, Ghavtadze M, Maisuradze T. Chaghiashvili N, et al. Eur J Case Rep Intern Med. 2025 Dec 3;12(12):005852. doi: 10.12890/2025_005852. eCollection 2025. Eur J Case Rep Intern Med. 2025. PMID: 41377781 Free PMC article.
Anti-glomerular basement membrane antibodies were tested to exclude Goodpasture's syndrome, tuberculosis was excluded (GeneXpert and multiplex biomarker test negative), and polymerase chain reaction testing for coronavirus disease-19 was negative. ...Cultures of blood and …
Anti-glomerular basement membrane antibodies were tested to exclude Goodpasture's syndrome, tuberculosis was excluded (GeneXpert and …
SARS-CoV-2 spike protein induces salivary gland dysfunction and immune infiltration in C57BL/6 mice.
Felix FA, Jiang Y, Zhou J, Li D, Zhou V, de Sousa SF, Byrd KM, Yu Q. Felix FA, et al. Front Immunol. 2025 Nov 21;16:1667597. doi: 10.3389/fimmu.2025.1667597. eCollection 2025. Front Immunol. 2025. PMID: 41357219 Free PMC article.
Salivary gland dysfunction and inflammation are common following SARS-CoV-2 infection. This study aimed to investigate the effects of SARS-CoV-2 spike and envelope proteins on glandular function in healthy C57BL/6 mice through direct intra-glandular injection into the subm …
Salivary gland dysfunction and inflammation are common following SARS-CoV-2 infection. This study aimed to investigate the effects of …
Mapping of the Antinuclear Autoantibodies in Sudanese patients infected with Human Immunodeficiency Virus after HAART receiving: A cross-sectional study.
Hajhamed NM, Mohammed SI, Hussein WA, Bakheit AM, Mohamed NS, Azhary A, Ahmed AE, Abdalla AE, Abdelbagi A, Allah HBSK, Ali MOM, Hamida ME. Hajhamed NM, et al. Sci Rep. 2025 Jul 2;15(1):23367. doi: 10.1038/s41598-025-06389-9. Sci Rep. 2025. PMID: 40604026 Free PMC article.
It is important to highlight that infection with the human immunodeficiency virus (HIV) may trigger chronic inflammation in people living with HIV/AIDS (PLWHA), impacting to the key immune cells such B and T lymphocytes, leading to development of autoantibodies which might …
It is important to highlight that infection with the human immunodeficiency virus (HIV) may trigger chronic inflammation in people li …
Acute Pericarditis: An Isolated Initial Manifestation of Systemic Lupus Erythematosus (SLE).
Gomez-Alvarez U, Vargas Torres CG, Sanchez Soberanes L, Grajeda Marin JM, Mora Castrejon JL. Gomez-Alvarez U, et al. Cureus. 2025 Nov 16;17(11):e97005. doi: 10.7759/cureus.97005. eCollection 2025 Nov. Cureus. 2025. PMID: 41416272 Free PMC article.
Pericarditis is an inflammation of the pericardium that may arise from multiple etiologies, including autoimmune diseases such as systemic lupus erythematosus (SLE). ...A pericardial friction rub was noted on physical examination, and cardiac MRI showed evidence of acute p …
Pericarditis is an inflammation of the pericardium that may arise from multiple etiologies, including autoimmune diseases such as sys …
Somatostatin Receptor Scintigraphy in Autoimmune Syndrome Induced by Silicone Breast Implants: Pre- and Postexplantation Findings.
Anzola LK, Ramirez S, Moreno S, Vargas C, Rojas S, Rivera JN. Anzola LK, et al. J Clin Med. 2025 Jun 11;14(12):4141. doi: 10.3390/jcm14124141. J Clin Med. 2025. PMID: 40565885 Free PMC article.
Autoantibody analysis revealed positivity in 66% of patients, with antinuclear antibodies being most frequent (30%). Conclusions:(99m)Tc-HYNIC-TOC scintigraphy effectively evaluates organ-specific inflammation in ASIA. Explantation reduces localized inflam …
Autoantibody analysis revealed positivity in 66% of patients, with antinuclear antibodies being most frequent (30%). Conclusio …
Exposure to Dietary Nitrite Exacerbates Lupus in MRL/lpr Mice by Enhancing Integrin Alpha M.
Qiu Y, Zhang Q, Yang X, Wen C, He Z, Wang M. Qiu Y, et al. Inflammation. 2025 Dec;48(6):4564-4578. doi: 10.1007/s10753-025-02347-9. Epub 2025 Aug 4. Inflammation. 2025. PMID: 40758225 Free PMC article.
ELISA quantification revealed elevated serum anti-double-stranded DNA antibodies (anti-dsDNA), antinuclear antibodies (ANA), and pro-inflammatory cytokines (IL-12p70, TNF-alpha), correlating with aggravated renal pathology in nitrite-exposed mice. ...
ELISA quantification revealed elevated serum anti-double-stranded DNA antibodies (anti-dsDNA), antinuclear antibodies ( …
Daratumumab in systemic lupus erythematosus: a single-arm phase 2 trial.
Ostendorf L, Zernicke J, Klotsche J, Kempkens R, Beenken AE, Biesen R, Cheng Q, Khodadadi L, Guerra GM, Heinrich F, Durek P, Burmester GR, Krönke G, Hiepe F, Mashreghi MF, Alexander T. Ostendorf L, et al. Nat Commun. 2026 Feb 3;17(1):1312. doi: 10.1038/s41467-026-69112-w. Nat Commun. 2026. PMID: 41629292 Free PMC article. Clinical Trial.
Systemic Treatment Strategies for Patients with Psoriasis and Psoriatic Arthritis in the Setting of ANA Positivity or Lupus Spectrum Disease: A Comprehensive Systematic Review.
Tjiu JW, Tsai TF. Tjiu JW, et al. Int J Mol Sci. 2026 Jan 22;27(2):1093. doi: 10.3390/ijms27021093. Int J Mol Sci. 2026. PMID: 41596733 Free PMC article. Review.
Psoriasis and psoriatic arthritis (PsA) occasionally coexist with antinuclear antibody (ANA) positivity, cutaneous lupus erythematosus (CLE), or systemic lupus erythematosus (SLE), creating one of the most challenging therapeutic overlap scenarios in immunodermatology. Div …
Psoriasis and psoriatic arthritis (PsA) occasionally coexist with antinuclear antibody (ANA) positivity, cutaneous lupus erythematosu …
A Case Report of Longitudinal Extensive Transverse Myelitis: Ruling Out the Known Perpetrators.
Khan M, Khalid A, Ali S, Khan AJ, Reza RR, Cardenas JA. Khan M, et al. Cureus. 2025 Oct 21;17(10):e95095. doi: 10.7759/cureus.95095. eCollection 2025 Oct. Cureus. 2025. PMID: 41280989 Free PMC article.
Autoimmune and infectious workup, including antineutrophil cytoplasmic antibodies (ANCA), thyroid peroxidase (TPO) antibodies, West Nile virus IgG/IgM, and rapid plasma reagin (RPR), was unremarkable. Erythrocyte sedimentation rate (ESR) was elevated at 46. Antin …
Autoimmune and infectious workup, including antineutrophil cytoplasmic antibodies (ANCA), thyroid peroxidase (TPO) antibodies, …
Effectiveness of shear wave elastography for assessing major salivary gland involvement in ankylosing spondylitis.
Atik I, Atik S, Gul E. Atik I, et al. Radiol Bras. 2025 Mar 11;58:e20240121. doi: 10.1590/0100-3984.2024.0121. eCollection 2025 Jan-Dec. Radiol Bras. 2025. PMID: 40094106 Free PMC article.
MATERIALS AND METHODS: This was a prospective controlled study of patients diagnosed with AS and exhibiting sicca symptoms (study group) and of healthy volunteers (control group). The levels of antinuclear, anti-Ro, and anti-La antibodies were determined in blood sa …
MATERIALS AND METHODS: This was a prospective controlled study of patients diagnosed with AS and exhibiting sicca symptoms (study group) and …
Uveitis associated with juvenile idiopathic arthritis and chronic idiopathic uveitis in children: A retrospective cohort study.
Yakovlev AA, Gaidar EV, Sorokina LS, Nikitina TN, Kalashnikova OV, Kostik MM. Yakovlev AA, et al. World J Clin Pediatr. 2025 Jun 9;14(2):100336. doi: 10.5409/wjcp.v14.i2.100336. eCollection 2025 Jun 9. World J Clin Pediatr. 2025. PMID: 40491729 Free PMC article.
In 53.6% of cases it followed arthritis. Both groups had similar onset ages, antinuclear antibodies/human leukocyte antigen positivity rates, and ESR levels, with a slight predominance of females (60.9% vs 42.5%, P = 0.062), and higher C-reactive protein levels in t …
In 53.6% of cases it followed arthritis. Both groups had similar onset ages, antinuclear antibodies/human leukocyte antigen po …
Retrospective, single-center analysis of autoimmune hepatitis in Yemeni adults: clinical features, treatment, and outcomes.
Reem A, Abdulsalam AS, Al-Asbahy A, Aldhorae K, Al-Shehari WA. Reem A, et al. BMC Immunol. 2026 Jan 7;27(1):9. doi: 10.1186/s12865-025-00796-3. BMC Immunol. 2026. PMID: 41501620 Free PMC article.
BACKGROUND: Autoimmune hepatitis (AIH) is a chronic liver disease in which the immune system of the body unintentionally targets liver cells, resulting in inflammation, liver damage, and cirrhosis if treatment is not received. Although the precise origin of AIH remains unk …
BACKGROUND: Autoimmune hepatitis (AIH) is a chronic liver disease in which the immune system of the body unintentionally targets liver cells …
Diagnosis and Management of Autoimmune Hepatitis After Hepatitis A in a Young Woman.
Patel S, Dixon C, Chokshi N, Giraldo S, Thiriveedi M, Dailey V. Patel S, et al. Am J Case Rep. 2025 May 27;26:e946795. doi: 10.12659/AJCR.946795. Am J Case Rep. 2025. PMID: 40420466 Free PMC article.
Autoimmune hepatitis is characterized by subacute to chronic liver inflammation, which can lead to liver cirrhosis if untreated. Both conditions remain uncommon in the United States. ...Further investigations detected IgG against Hep A, positive anti-nuclear antibodies …
Autoimmune hepatitis is characterized by subacute to chronic liver inflammation, which can lead to liver cirrhosis if untreated. Both …
A Rare Case of Granulomatosis With Polyangiitis With Cutaneous Pyoderma Gangrenosum-Like Lesions of the Bilateral Parotid Glands.
Short SH, McGlone M, Ohlstein JF. Short SH, et al. Ear Nose Throat J. 2025 Jul 14:1455613251345431. doi: 10.1177/01455613251345431. Online ahead of print. Ear Nose Throat J. 2025. PMID: 40658486 Free article.
A punch biopsy indicated granulomatous inflammation with necrosis, and autoimmune lab work showed elevated antinuclear antibody, erythrocyte sedimentation rate, C-reactive protein, and cytoplasmic antineutrophilic cytoplasmic antibodies levels. ...
A punch biopsy indicated granulomatous inflammation with necrosis, and autoimmune lab work showed elevated antinuclear antibod …
A Double-Edged Sword: The Clinical Dilemma of Lupus Nephritis and Antineutrophil Cytoplasmic Antibody-Associated Vasculitis Overlap Syndrome.
Probasco L, Fernandez Placencia AC. Probasco L, et al. Cureus. 2025 Dec 6;17(12):e98569. doi: 10.7759/cureus.98569. eCollection 2025 Dec. Cureus. 2025. PMID: 41357727 Free PMC article.
This diagnostic entity presents unique challenges, particularly in older adults with rapidly progressive glomerulonephritis (RPGN) and systemic inflammation. We describe a diagnostically challenging case of a 74-year-old woman with a history of interstitial lung disease, p …
This diagnostic entity presents unique challenges, particularly in older adults with rapidly progressive glomerulonephritis (RPGN) and syste …
Cutaneous Manifestations of Primary Sjögren's Syndrome: Pyoderma Gangrenosum as a Rare Initial Presentation - A Case Report and Literature Review.
Devadkar A, Kanitkar S. Devadkar A, et al. Ann Afr Med. 2025 Sep 15. doi: 10.4103/aam.aam_262_25. Online ahead of print. Ann Afr Med. 2025. PMID: 40952810 Free article. English, French.
Laboratory investigations revealed elevated inflammatory markers, positive antinuclear antibodies, and strongly positive anti-SSA/Ro and anti-SSB/La antibodies. Histopathological examination confirmed neutrophilic dermatosis compatible with PG. Schirmer's tes …
Laboratory investigations revealed elevated inflammatory markers, positive antinuclear antibodies, and strongly positive anti- …
A Tale of Overlapping Autoimmune Serologies: Diagnosing Hydralazine-Induced Antineutrophilic Cytoplasmic Antibody (ANCA)-Associated Vasculitis (AAV) Related With Isolated Pulmonary Involvement.
Thapa P, Yadav I, Vinagolu-Baur J. Thapa P, et al. Cureus. 2025 Aug 7;17(8):e89547. doi: 10.7759/cureus.89547. eCollection 2025 Aug. Cureus. 2025. PMID: 40918893 Free PMC article.
Diagnosis includes clinical evaluation, serological testing for ANCA, and histopathological examination, confirmed by necrotizing granulomatous inflammation in affected tissues. This case report presents a rare presentation of hydralazine-induced AAV limited to the lungs, …
Diagnosis includes clinical evaluation, serological testing for ANCA, and histopathological examination, confirmed by necrotizing granulomat …
Anti-PL-12 and Interstitial Lung Disease as the First Signs of Antisynthetase Syndrome in Patients With Previously Diagnosed Systemic Lupus Erythematosus.
Djuran I, Ljubicic B, Lazarevic A, Popovic M, Knezevic V. Djuran I, et al. Cureus. 2025 Sep 29;17(9):e93472. doi: 10.7759/cureus.93472. eCollection 2025 Sep. Cureus. 2025. PMID: 41179010 Free PMC article.
Laboratory testing demonstrated a strong antinuclear antibody (ANA) reactivity on Hep-2 cells and low anti-double-stranded DNA (anti-dsDNA) levels (<10 IU/ml). Extended myositis panel testing revealed marked positivity for anti-PL-12 and anti-Ro-52 antibodies. Gi …
Laboratory testing demonstrated a strong antinuclear antibody (ANA) reactivity on Hep-2 cells and low anti-double-stranded DNA (anti- …
Isolated celiac artery vasculitis: a cause of recurrent abdominal pain in a young adult: a case report.
Hajihashemi A, Tavallaeinejad P, Geravandi M. Hajihashemi A, et al. J Med Case Rep. 2025 Mar 3;19(1):89. doi: 10.1186/s13256-025-05108-2. J Med Case Rep. 2025. PMID: 40033455 Free PMC article.
BACKGROUND: Vasculitis encompasses a group of disorders characterized by inflammation of blood vessel walls, leading to diverse clinical presentations on the basis of the size and location of the affected vessels. ...This case highlights the importance of recognizing isola …
BACKGROUND: Vasculitis encompasses a group of disorders characterized by inflammation of blood vessel walls, leading to diverse clini …
Systems Pharmacology and Multi-Omics Elucidation of Irpex lacteus Polysaccharides in the Treatment of Lupus Nephritis Through PI3K/AKT/NF-κB Pathway Inhibition.
Ji G, Yao Z, Zhao Y, Li C, Yang B, Li Z, Kuang M, Wang H, Wu X, Yuan H, Deng Y, Wang S, Wang H. Ji G, et al. Pharmaceuticals (Basel). 2025 Oct 27;18(11):1619. doi: 10.3390/ph18111619. Pharmaceuticals (Basel). 2025. PMID: 41304865 Free PMC article.
Results: PCP treatment significantly improved renal function in MRL/lpr mice, normalizing serum levels of anti-nuclear antibodies (ANA), anti-double-stranded DNA antibodies (anti-dsDNA), anti-Sm antibody (Sm), creatinine (Cr), blood urea nitrogen (BUN), interleukin- …
Results: PCP treatment significantly improved renal function in MRL/lpr mice, normalizing serum levels of anti-nuclear antibodies (AN …
Lupus-Associated Knee Pain: An Atypical Presentation of Systemic Lupus Erythematosus in a Young Male.
Pessoa AL, Teixeira Reis A, Santos Costa A, Rodrigues M, De Almeida Robalo C. Pessoa AL, et al. Cureus. 2025 Dec 18;17(12):e99557. doi: 10.7759/cureus.99557. eCollection 2025 Dec. Cureus. 2025. PMID: 41552240 Free PMC article.
We report a case of a 19-year-old male presenting with bilateral inflammatory knee pain initially interpreted as patellofemoral chondromalacia. 18F-fluorodeoxyglucose positron emission tomography-computed tomography (18F-FDG PET-CT) revealed multiple symmetric hypermetabolic oste …
We report a case of a 19-year-old male presenting with bilateral inflammatory knee pain initially interpreted as patellofemoral chondromalac …
Drug-Induced Lupus Erythematosus After 14 Years of Carbamazepine Use in a Patient With Neuromyelitis Optica Spectrum Disorder: A Case Report.
Ayuzawa-Takeda N, Saito K, Yanagida H, Oeda T. Ayuzawa-Takeda N, et al. Am J Case Rep. 2025 Dec 18;26:e949233. doi: 10.12659/AJCR.949233. Am J Case Rep. 2025. PMID: 41411232 Free PMC article.
Neuromyelitis optica spectrum disorder (NMOSD), an autoimmune disease characterized by recurrent inflammation of the central nervous system, frequently coexists with other autoimmune disorders. ...She presented with fatigue, weight loss, intermittent fever, and pleural eff …
Neuromyelitis optica spectrum disorder (NMOSD), an autoimmune disease characterized by recurrent inflammation of the central nervous …
Severe tenosynovitis with rapidly fluctuating power Doppler activity, a clue for the diagnosis of Blau syndrome: a case report.
Pastore S, Carraro C, De Martino E, Pin A, Bruno I, Zanotta N, Valencic E, Tommasini A, Taddio A. Pastore S, et al. Front Pediatr. 2025 Aug 13;13:1662832. doi: 10.3389/fped.2025.1662832. eCollection 2025. Front Pediatr. 2025. PMID: 40881804 Free PMC article.
Blood tests showed lymphopenia, elevated inflammation markers and positivity of anti-nuclear antibodies. Ultrasound revealed severe tenosynovitis with no power Doppler signal. ...
Blood tests showed lymphopenia, elevated inflammation markers and positivity of anti-nuclear antibodies. Ultrasound revealed s …
Hepatic granulomas heralding eosinophilic granulomatosis with polyangiitis overlapping with Sjögren's syndrome.
Achour TB, Saïd F, Chérif A, Jridi M, Ghorbel IB, Naceur I, Smiti M. Achour TB, et al. Hepatol Forum. 2025 Sep 24;7(1):77-80. doi: 10.14744/hf.2025.45561. eCollection 2026. Hepatol Forum. 2025. PMID: 41589212 Free PMC article.
Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAVs) encompass a group of rare autoimmune diseases characterized by granuloma formation and/or inflammation of small vessels. The clinical spectrum of AAV varies widely. Liver involvement is exceptional, …
Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAVs) encompass a group of rare autoimmune diseases characterized by gr …
Vitamin D Status in Rheumatology Patients with Inflammatory Compared with Non-Inflammatory Diagnoses: Inflammatory and Autoimmune Markers Are Not Associated with Vitamin D Levels.
Schäfer A, Kovacs MS, Nigg A, Feuchtenberger M. Schäfer A, et al. Nutrients. 2026 Jan 20;18(2):326. doi: 10.3390/nu18020326. Nutrients. 2026. PMID: 41599939 Free PMC article.
METHODS: In this retrospective, observational study, we used electronic health record data from patients presenting for their first visit at a large rheumatology clinic to assess vitamin D levels and deficiency based on diagnosis, and to evaluate the association between vitamin D …
METHODS: In this retrospective, observational study, we used electronic health record data from patients presenting for their first visit at …