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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1946 2
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1958 6
1959 2
1963 1
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1968 1
1969 2
1970 4
1971 2
1972 2
1974 1
1975 1
1976 3
1977 4
1978 1
1979 1
1980 1
1981 7
1982 3
1983 5
1984 9
1985 6
1986 8
1987 5
1988 15
1989 9
1990 11
1991 9
1992 9
1993 20
1994 15
1995 21
1996 25
1997 27
1998 43
1999 52
2000 61
2001 67
2002 86
2003 107
2004 125
2005 166
2006 169
2007 180
2008 211
2009 190
2010 226
2011 260
2012 297
2013 319
2014 330
2015 391
2016 367
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2024 201

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Page 1
The Therapeutic Potential of Apigenin.
Salehi B, Venditti A, Sharifi-Rad M, Kręgiel D, Sharifi-Rad J, Durazzo A, Lucarini M, Santini A, Souto EB, Novellino E, Antolak H, Azzini E, Setzer WN, Martins N. Salehi B, et al. Int J Mol Sci. 2019 Mar 15;20(6):1305. doi: 10.3390/ijms20061305. Int J Mol Sci. 2019. PMID: 30875872 Free PMC article. Review.
The largest group of naturally-occurring polyphenols are the flavonoids, including apigenin. The present work is an updated overview of apigenin, focusing on its health-promoting effects/therapeutic functions and, in particular, results of in vivo research. ...Final …
The largest group of naturally-occurring polyphenols are the flavonoids, including apigenin. The present work is an updated overview …
Apigenin inhibits fibrous scar formation after acute spinal cord injury through TGFbeta/SMADs signaling pathway.
Jin Z, Tian L, Zhang Y, Zhang X, Kang J, Dong H, Huang N, Pan L, Ning B. Jin Z, et al. CNS Neurosci Ther. 2022 Nov;28(11):1883-1894. doi: 10.1111/cns.13929. Epub 2022 Jul 30. CNS Neurosci Ther. 2022. PMID: 35906830 Free PMC article.
AIM: To investigate the effect of apigenin on fibrous scar formation after mouse spinal cord injury (SCI). ...NIH-3 T3 cells and mouse primary spinal cord fibroblasts, alpha-Smooth muscle actin (alpha-SMA), collagen 1, and fibronectin were used to evaluate apigenin' …
AIM: To investigate the effect of apigenin on fibrous scar formation after mouse spinal cord injury (SCI). ...NIH-3 T3 cells and mous …
Apigenin Alleviates Autoimmune Uveitis by Inhibiting Microglia M1 Pro-Inflammatory Polarization.
Shu N, Zhang Z, Wang X, Li R, Li W, Liu X, Zhang Q, Jiang Z, Tao L, Zhang L, Hou S. Shu N, et al. Invest Ophthalmol Vis Sci. 2023 May 1;64(5):21. doi: 10.1167/iovs.64.5.21. Invest Ophthalmol Vis Sci. 2023. PMID: 37219511 Free PMC article.
PURPOSE: Apigenin is a natural small molecule compound widely present in various vegetables and fruits. ...In vivo, Western blotting was used to quantify protein levels of classical inflammatory factors, microglial M1/M2 markers and the tight junction protein of the blood- …
PURPOSE: Apigenin is a natural small molecule compound widely present in various vegetables and fruits. ...In vivo, Western blotting …
Apigenin as an anticancer agent.
Imran M, Aslam Gondal T, Atif M, Shahbaz M, Batool Qaisarani T, Hanif Mughal M, Salehi B, Martorell M, Sharifi-Rad J. Imran M, et al. Phytother Res. 2020 Aug;34(8):1812-1828. doi: 10.1002/ptr.6647. Epub 2020 Feb 14. Phytother Res. 2020. PMID: 32059077 Review.
Apigenin is an edible plant-derived flavonoid that has been reported as an anticancer agent in several experimental and biological studies. ...The expressions of NF-kappaB p105/p50, PI3K, Akt, and the phosphorylation of p-Akt decreases after treatment with apigenin. …
Apigenin is an edible plant-derived flavonoid that has been reported as an anticancer agent in several experimental and biological st …
The Anticancer Potential of Apigenin Via Immunoregulation.
Xu L, Zaky MY, Yousuf W, Ullah A, Abdelbaset GR, Zhang Y, Ahmed OM, Liu S, Liu H. Xu L, et al. Curr Pharm Des. 2021;27(4):479-489. doi: 10.2174/1381612826666200713171137. Curr Pharm Des. 2021. PMID: 32660399 Review.
Apigenin is an edible flavonoid widely distributed in natural plants, including most vegetables and fruits. ...However, the current understanding of this emerging role of apigenin still remains limited. Therefore, in the present review, recent advances on the immuno …
Apigenin is an edible flavonoid widely distributed in natural plants, including most vegetables and fruits. ...However, the current u …
Apigenin's Therapeutic Potential Against Viral Infection.
Lee IG, Lee J, Hong SH, Seo YJ. Lee IG, et al. Front Biosci (Landmark Ed). 2023 Oct 17;28(10):237. doi: 10.31083/j.fbl2810237. Front Biosci (Landmark Ed). 2023. PMID: 37919082 Free article. Review.
Despite its many anti-inflammatory, anti-oxidant, anti-cancer, anti-bacterial, and other beneficial bioactivities, existing reviews have yet to focus on apigenin's antiviral effects. Therefore, this review elucidates apigenin's therapeutic and antivira …
Despite its many anti-inflammatory, anti-oxidant, anti-cancer, anti-bacterial, and other beneficial bioactivities, existing reviews have yet …
Boosting Anti-tumour Immunity Using Adjuvant Apigenin.
Huang J, Chen X, Chang Z, Xiao C, Najafi M. Huang J, et al. Anticancer Agents Med Chem. 2023;23(3):266-277. doi: 10.2174/1871520622666220523151409. Anticancer Agents Med Chem. 2023. PMID: 35616683 Review.
To stimulate anti-tumour immunity, suppression of the secretion and interactions of immunosuppressive cells, on the other hand, stimulation of proliferation and activation of natural killer (NK) cells and CD8+ T lymphocytes are required. Apigenin is a flavone with anticanc …
To stimulate anti-tumour immunity, suppression of the secretion and interactions of immunosuppressive cells, on the other hand, stimulation …
Some Nanocarrier's Properties and Chemical Interaction Mechanisms with Flavones.
Espíndola C. Espíndola C. Molecules. 2023 Mar 22;28(6):2864. doi: 10.3390/molecules28062864. Molecules. 2023. PMID: 36985836 Free PMC article. Review.
Flavones such as 7,8-dihydroxyflavone (tropoflavin), 5,6,7-trihydroxyflavone (baicalein), 3',4',5,6-tetrahydroxyflavone (luteolin), 3,3',4',5,5',7-hexahydroxyflavone (myricetin), 4',5,7-trihydroxyflavone (apigenin), and 5,7-dihydroxyflavone (chrysin) are important both for …
Flavones such as 7,8-dihydroxyflavone (tropoflavin), 5,6,7-trihydroxyflavone (baicalein), 3',4',5,6-tetrahydroxyflavone (luteolin), 3,3',4', …
Apigenin: A Therapeutic Agent for Treatment of Skin Inflammatory Diseases and Cancer.
Yoon JH, Kim MY, Cho JY. Yoon JH, et al. Int J Mol Sci. 2023 Jan 12;24(2):1498. doi: 10.3390/ijms24021498. Int J Mol Sci. 2023. PMID: 36675015 Free PMC article. Review.
An overreaction to these agents causes severe skin diseases, including atopic dermatitis, pruritus, psoriasis, skin cancer, and vitiligo. Members of the flavonoid family include apigenin, quercetin, luteolin, and kaempferol. Of these, apigenin has been used as a die …
An overreaction to these agents causes severe skin diseases, including atopic dermatitis, pruritus, psoriasis, skin cancer, and vitiligo. Me …
6,707 results