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1994 1
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2003 1
2005 2
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2008 4
2009 5
2010 3
2011 11
2012 10
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2015 19
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2018 20
2019 28
2020 25
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186 results
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Fucoidan Promotes Apoptosis and Inhibits EMT of Breast Cancer Cells.
He X, Xue M, Jiang S, Li W, Yu J, Xiang S. He X, et al. Biol Pharm Bull. 2019;42(3):442-447. doi: 10.1248/bpb.b18-00777. Biol Pharm Bull. 2019. PMID: 30828076 Free article.
Conditioned serum from fucoidan-treated rats significantly suppressed cell proliferation and enhanced apoptosis. Cell migration and invasion were also significantly decreased. ...Conditioned serum of rats treated with fucoidan could inhibit the proliferation …
Conditioned serum from fucoidan-treated rats significantly suppressed cell proliferation and enhanced apoptosis. Cell migratio …
Caspase-dependent and caspase-independent induction of apoptosis in breast cancer by fucoidan via the PI3K/AKT/GSK3β pathway in vivo and in vitro.
Xue M, Ji X, Xue C, Liang H, Ge Y, He X, Zhang L, Bian K, Zhang L. Xue M, et al. Biomed Pharmacother. 2017 Oct;94:898-908. doi: 10.1016/j.biopha.2017.08.013. Epub 2017 Aug 12. Biomed Pharmacother. 2017. PMID: 28810530
Results in vitro fucoidan treatment inhibited proliferation and induced apoptosis in MDA-MB-231 cells. Western blotting detected that Cyt C and Smac were released into the cell cytoplasm and that caspase-3 and caspase-9 were activated in MDA-MB-231 cells. The levels …
Results in vitro fucoidan treatment inhibited proliferation and induced apoptosis in MDA-MB-231 cells. Western blotting detect …
Fucoidan delays apoptosis and induces pro-inflammatory cytokine production in human neutrophils.
Jin JO, Yu Q. Jin JO, et al. Int J Biol Macromol. 2015 Feb;73:65-71. doi: 10.1016/j.ijbiomac.2014.10.059. Epub 2014 Nov 18. Int J Biol Macromol. 2015. PMID: 25445688
Although some immune modulatory effects of fucoidan have been elucidated, the effects of fucoidan on the apoptosis and activation of human neutrophils have not been investigated. In this study, we demonstrated that fucoidan purified from the brown seaw …
Although some immune modulatory effects of fucoidan have been elucidated, the effects of fucoidan on the apoptosis and …
Fucoidan Induces ROS-Dependent Apoptosis in 5637 Human Bladder Cancer Cells by Downregulating Telomerase Activity via Inactivation of the PI3K/Akt Signaling Pathway.
Han MH, Lee DS, Jeong JW, Hong SH, Choi IW, Cha HJ, Kim S, Kim HS, Park C, Kim GY, Moon SK, Kim WJ, Hyun Choi Y. Han MH, et al. Drug Dev Res. 2017 Feb;78(1):37-48. doi: 10.1002/ddr.21367. Epub 2016 Sep 21. Drug Dev Res. 2017. PMID: 27654302
Fucoidan-treatment also suppressed activation of the PI3K/Akt signaling pathway. Inhibition of PI3K/Akt signaling enhanced fucoidan-induced apoptosis and anti-telomerase activity. Meanwhile, fucoidan treatment increased the generation of intracellular
Fucoidan-treatment also suppressed activation of the PI3K/Akt signaling pathway. Inhibition of PI3K/Akt signaling enhanced fucoida
Fucoidan induces apoptosis of HepG2 cells by down-regulating p-Stat3.
Roshan S, Liu YY, Banafa A, Chen HJ, Li KX, Yang GX, He GY, Chen MJ. Roshan S, et al. J Huazhong Univ Sci Technolog Med Sci. 2014 Jun;34(3):330-336. doi: 10.1007/s11596-014-1278-0. Epub 2014 Jun 18. J Huazhong Univ Sci Technolog Med Sci. 2014. PMID: 24939294
In the meantime, Cyclin B1 and CDK1 were down-regulated by fucoidan treatment. Down-regulation of p-Stat3 by fucoidan resulted in apoptosis and an increase in ROS in response to fucoidan exposure. We therefore concluded that fucoidan induces …
In the meantime, Cyclin B1 and CDK1 were down-regulated by fucoidan treatment. Down-regulation of p-Stat3 by fucoidan resulted …
Antitumor activity of fucoidan in anaplastic thyroid cancer via apoptosis and anti-angiogenesis.
Shen HY, Li LZ, Xue KC, Hu DD, Gao YJ. Shen HY, et al. Mol Med Rep. 2017 May;15(5):2620-2624. doi: 10.3892/mmr.2017.6338. Epub 2017 Mar 16. Mol Med Rep. 2017. PMID: 28447753
The present study demonstrated the effect of fucoidan, isolated from Fucus vesiculosus, on cell growth and apoptosis in anaplastic thyroid cancer cells. ...Therefore, fucoidan inhibited cell growth, induced apoptosis and suppressed angiogenesis in the …
The present study demonstrated the effect of fucoidan, isolated from Fucus vesiculosus, on cell growth and apoptosis in anapla …
In vitro anticancer activity of fucoidan extracted from Sargassum cinereum against Caco-2 cells.
Narayani SS, Saravanan S, Ravindran J, Ramasamy MS, Chitra J. Narayani SS, et al. Int J Biol Macromol. 2019 Oct 1;138:618-628. doi: 10.1016/j.ijbiomac.2019.07.127. Epub 2019 Jul 22. Int J Biol Macromol. 2019. PMID: 31344415
Fucoidan inhibited growth of Caco-2 cells in a dose-dependent manner. IC(50) concentration of fucoidan was found to be 250 μg/ml. AO/EB, Hoechst and Annexin V/PI staining confirmed the apoptosis induced by fucoidan in Caco-2 cells. Fucoidan was
Fucoidan inhibited growth of Caco-2 cells in a dose-dependent manner. IC(50) concentration of fucoidan was found to be 250 μg/
Fucoidan from marine brown algae attenuates pancreatic cancer progression by regulating p53 - NFκB crosstalk.
Delma CR, Thirugnanasambandan S, Srinivasan GP, Raviprakash N, Manna SK, Natarajan M, Aravindan N. Delma CR, et al. Phytochemistry. 2019 Nov;167:112078. doi: 10.1016/j.phytochem.2019.112078. Epub 2019 Aug 23. Phytochemistry. 2019. PMID: 31450091
Fucoidans induced apoptosis, activated caspase -3, -8 and -9, and cleaved Poly ADP ribose polymerase (PARP). Pathway-specific transcriptional analysis recognized inhibition of 57 and 38 nuclear factor κB (NFκB) pathway molecules with fucoidan-F5 in MiaPaCa-2
Fucoidans induced apoptosis, activated caspase -3, -8 and -9, and cleaved Poly ADP ribose polymerase (PARP). Pathway-specific
Fucoidan Induces Apoptosis of HT-29 Cells via the Activation of DR4 and Mitochondrial Pathway.
Bai X, Wang Y, Hu B, Cao Q, Xing M, Song S, Ji A. Bai X, et al. Mar Drugs. 2020 Apr 20;18(4):220. doi: 10.3390/md18040220. Mar Drugs. 2020. PMID: 32326052 Free PMC article.
Fucoidan has a variety of pharmacological activities, but the understanding of the mechanism of fucoidan-induced apoptosis of colorectal cancer cells remains limited. ...In conclusion, the current work identified the mechanism of fucoidan-induced ap
Fucoidan has a variety of pharmacological activities, but the understanding of the mechanism of fucoidan-induced apoptosis
Brown seaweed fucoidan: biological activity and apoptosis, growth signaling mechanism in cancer.
Senthilkumar K, Manivasagan P, Venkatesan J, Kim SK. Senthilkumar K, et al. Int J Biol Macromol. 2013 Sep;60:366-74. doi: 10.1016/j.ijbiomac.2013.06.030. Epub 2013 Jun 28. Int J Biol Macromol. 2013. PMID: 23817097 Review.
Apoptosis is mainly regulated by cell growth signaling molecules. Number of research studies evidenced that fucoidan shown to induce cytotoxicity of various cancer cells, induces apoptosis, and inhibits invasion, metastasis and angiogenesis of cancer cells. .
Apoptosis is mainly regulated by cell growth signaling molecules. Number of research studies evidenced that fucoidan shown to
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