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Arctium lappa root extract containing L-arginine prevents TNF-alpha-induced early atherosclerosis in vitro and in vivo.
Lee J, Ha SJ, Park J, Kim YH, Lee NH, Kim YE, Hong YS, Song KM. Lee J, et al. Nutr Res. 2020 May;77:85-96. doi: 10.1016/j.nutres.2020.03.003. Epub 2020 Mar 21. Nutr Res. 2020. PMID: 32388084
Atherosclerosis is a chronic inflammatory disease affecting the aorta and is a major cause of cardiovascular disease. Arctium lappa root is a plant widely used in traditional Chinese medicine (TCM), and Arctium lappa root extract (ALE) has been reported to ex
Atherosclerosis is a chronic inflammatory disease affecting the aorta and is a major cause of cardiovascular disease. Arctium
Arctium lappa L. polysaccharide can regulate lipid metabolism in type 2 diabetic rats through the SREBP-1/SCD-1 axis.
Chen M, Xu J, Wang Y, Wang Z, Guo L, Li X, Huang L. Chen M, et al. Carbohydr Res. 2020 Aug;494:108055. doi: 10.1016/j.carres.2020.108055. Epub 2020 Jun 7. Carbohydr Res. 2020. PMID: 32535406
In the analysis of risk factors of diabetes mellitus with coronary heart disease, dyslipidemia is the most important. Previous studies have found that Arctium lappa L. polysaccharide (ALP) can regulate lipid metabolism in type 1 diabetic rats, but it has not been studied i …
In the analysis of risk factors of diabetes mellitus with coronary heart disease, dyslipidemia is the most important. Previous studies have …
Protective effects of Arctium lappa L. root extracts (AREs) on high fat diet induced quail atherosclerosis.
Wang Z, Li P, Wang C, Jiang Q, Zhang L, Cao Y, Zhong W, Wang C. Wang Z, et al. BMC Complement Altern Med. 2016 Jan 8;16:6. doi: 10.1186/s12906-016-0987-2. BMC Complement Altern Med. 2016. PMID: 26746431 Free PMC article.
BACKGROUND: This study was designed to evaluate the protective effects of Arctium lappa L. root extracts (AREs) from different extraction methods (aqueous, ethanol, chloroform and flavone) on atherosclerosis. ...
BACKGROUND: This study was designed to evaluate the protective effects of Arctium lappa L. root extracts (AREs) from different extrac …
Arctigenin promotes cholesterol efflux from THP-1 macrophages through PPAR-γ/LXR-α signaling pathway.
Xu X, Li Q, Pang L, Huang G, Huang J, Shi M, Sun X, Wang Y. Xu X, et al. Biochem Biophys Res Commun. 2013 Nov 15;441(2):321-6. doi: 10.1016/j.bbrc.2013.10.050. Epub 2013 Oct 17. Biochem Biophys Res Commun. 2013. PMID: 24140409
Cholesterol efflux from macrophages is a critical mechanism to prevent the development of atherosclerosis. Here, we sought to investigate the effects of arctigenin, a bioactive component of Arctium lappa, on the cholesterol efflux in oxidized low-density lipoprotein …
Cholesterol efflux from macrophages is a critical mechanism to prevent the development of atherosclerosis. Here, we sought to investi …