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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1969 1
1970 1
1971 1
1974 1
1975 1
1977 1
1979 3
1980 2
1981 4
1982 2
1983 1
1984 7
1985 8
1986 22
1987 17
1988 16
1989 15
1990 20
1991 30
1992 37
1993 37
1994 51
1995 60
1996 43
1997 74
1998 87
1999 77
2000 67
2001 77
2002 77
2003 73
2004 89
2005 88
2006 92
2007 103
2008 97
2009 110
2010 132
2011 122
2012 123
2013 169
2014 122
2015 106
2016 122
2017 110
2018 102
2019 92
2020 96
2021 91
2022 79
2023 93
2024 81
2025 95
2026 23

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2,894 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
The Effect of Amino Acids on Wound Healing: A Systematic Review and Meta-Analysis on Arginine and Glutamine.
Arribas-López E, Zand N, Ojo O, Snowden MJ, Kochhar T. Arribas-López E, et al. Nutrients. 2021 Jul 22;13(8):2498. doi: 10.3390/nu13082498. Nutrients. 2021. PMID: 34444657 Free PMC article.
This study aims to perform a systematic review and meta-analysis of the effect of arginine and glutamine supplementation on wound healing. PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines were followed for the systematic review and ten …
This study aims to perform a systematic review and meta-analysis of the effect of arginine and glutamine supplementation on wound hea …
The Potential Role of Arginine Supplements on Erectile Dysfunction: A Systemic Review and Meta-Analysis.
Rhim HC, Kim MS, Park YJ, Choi WS, Park HK, Kim HG, Kim A, Paick SH. Rhim HC, et al. J Sex Med. 2019 Feb;16(2):223-234. doi: 10.1016/j.jsxm.2018.12.002. J Sex Med. 2019. PMID: 30770070
INTRODUCTION: The efficacy and safety of arginine supplements in erectile dysfunction (ED) remain debatable. AIM: To assess the potential role of arginine supplements on ED as alternatives to phosphodiesterase inhibitors. ...Subgroup analysis for arginine alo …
INTRODUCTION: The efficacy and safety of arginine supplements in erectile dysfunction (ED) remain debatable. AIM: To assess the poten …
Arginine or Hypertonic Saline-Stimulated Copeptin to Diagnose AVP Deficiency.
Refardt J, Atila C, Chifu I, Ferrante E, Erlic Z, Drummond JB, Indirli R, Drexhage RC, Sailer CO, Widmer A, Felder S, Powlson AS, Hutter N, Vogt DR, Gurnell M, Soares BS, Hofland J, Beuschlein F, Fassnacht M, Winzeler B, Christ-Crain M. Refardt J, et al. N Engl J Med. 2023 Nov 16;389(20):1877-1887. doi: 10.1056/NEJMoa2306263. N Engl J Med. 2023. PMID: 37966286 Clinical Trial.
Arginine-stimulated copeptin has shown similar diagnostic accuracy but with a simpler test protocol. However, data are lacking from a head-to-head comparison between arginine-stimulated copeptin and hypertonic saline-stimulated copeptin in the diagnosis of AVP defic …
Arginine-stimulated copeptin has shown similar diagnostic accuracy but with a simpler test protocol. However, data are lacking from a …
L-Arginine and L-Citrulline for Prevention and Treatment of Pre-Eclampsia: A Systematic Review and Meta-Analysis.
Makama M, McDougall ARA, Cao J, Mills K, Nguyen PY, Hastie R, Ammerdorffer A, Gülmezoglu AM, Vogel JP. Makama M, et al. BJOG. 2025 May;132(6):698-708. doi: 10.1111/1471-0528.18070. Epub 2025 Jan 12. BJOG. 2025. PMID: 39800868 Free PMC article.
BACKGROUND: Evidence suggests L-arginine may be effective at reducing pre-eclampsia and related outcomes. However, whether L-arginine can prevent or only treat pre-eclampsia, and thus the target population and timing of initiation, remains unknown. OBJECTIVES: To ev …
BACKGROUND: Evidence suggests L-arginine may be effective at reducing pre-eclampsia and related outcomes. However, whether L-argin …
A Scoping Review on Arginine in Caries Prevention.
Bijle MN, Ekambaram M, Yiu CKY. Bijle MN, et al. J Evid Based Dent Pract. 2020 Sep;20(3):101470. doi: 10.1016/j.jebdp.2020.101470. Epub 2020 Jul 2. J Evid Based Dent Pract. 2020. PMID: 32921383
OBJECTIVES: Emerging science on arginine or arginine formulations has driven the need to examine the research in the field. ...Until now, three arginine variants have been investigated with l-arginine monohydrochloride as the least explored variant. .. …
OBJECTIVES: Emerging science on arginine or arginine formulations has driven the need to examine the research in the field. .. …
Arginine on immune function and post-operative obstructions in colorectal cancer patients: a meta-analysis.
Ouyang Z, Chen P, Zhang M, Wu S, Qin Z, Zhou L. Ouyang Z, et al. BMC Cancer. 2024 Sep 2;24(1):1089. doi: 10.1186/s12885-024-12858-7. BMC Cancer. 2024. PMID: 39223466 Free PMC article.
BACKGROUND: The aim of this study is to investigate the impact of arginine on immune function and postoperative complications in colorectal cancer (CRC) patients. ...However, the CD4(+)/CD8(+) ratio decreased significantly (SMD=1.37, 95% CI: 0.88-1.86) in the same argin …
BACKGROUND: The aim of this study is to investigate the impact of arginine on immune function and postoperative complications in colo …
Circulating arginine metabolites in Alzheimer's disease and vascular dementia: A systematic review and meta-analysis.
Zinellu A, Tommasi S, Sedda S, Mangoni AA. Zinellu A, et al. Ageing Res Rev. 2023 Dec;92:102139. doi: 10.1016/j.arr.2023.102139. Epub 2023 Nov 23. Ageing Res Rev. 2023. PMID: 38007048 Free article.
METHODS: We conducted a systematic review and meta-analysis of the circulating concentrations of arginine metabolites linked to NO synthesis, arginine, citrulline, asymmetric (ADMA) and symmetric (SDMA) dimethylarginine, and ornithine, in Alzheimer's disease and vas …
METHODS: We conducted a systematic review and meta-analysis of the circulating concentrations of arginine metabolites linked to NO sy …
l-arginine supplementation improved neonatal outcomes in pregnancies with hypertensive disorder or intrauterine growth restriction: A systematic review and meta-analysis of randomized controlled trials.
Xu L, Wang X, Wang C, Li W, Liu H. Xu L, et al. Clin Nutr. 2022 Jul;41(7):1512-1522. doi: 10.1016/j.clnu.2022.05.014. Epub 2022 May 23. Clin Nutr. 2022. PMID: 35667267
BACKGROUND & AIMS: Previous research established that the availability of l-arginine affects placental vascular development and fetal growth. However, practical details associated with the effects of l-arginine supplementation on the neonatal outcomes of hyperte …
BACKGROUND & AIMS: Previous research established that the availability of l-arginine affects placental vascular development and f …
Arginine Therapy for Pain in Sickle Cell Disease: A Phase-2 Randomized, Placebo-Controlled Trial.
Morris CR, Hatabah D, Korman R, Gillespie S, Bakshi N, Brown LA, Harris F, Leake D, Rees CA, Khemani K, Vichinsky EP, Locke A, Wynn B, Griffiths MA, Wilkinson H, Kumari P, Sudmeier L, Shiva S, Dampier CD. Morris CR, et al. Am J Hematol. 2025 Jul;100(7):1119-1131. doi: 10.1002/ajh.27692. Epub 2025 Apr 24. Am J Hematol. 2025. PMID: 40270092 Clinical Trial.
Arginine was low at presentation in 79% of patients (mean 50 28 muM), and increased with arginine therapy (p < 0.001). ...SCD-VOE is associated with an acquired arginine deficiency that correlates with worse clinical outcomes. Arginine improved mi …
Arginine was low at presentation in 79% of patients (mean 50 28 muM), and increased with arginine therapy (p < 0.001). .. …
L-arginine impact on inflammatory and cardiac markers in patients undergoing coronary artery bypass graft: a systematic review and meta-analysis of randomized controlled trials.
Mohammadi Z, Ravankhah M, Ahmadi M, Keshavarzian O, Azari I, Abdollahi M, Rezaei M, Akbari H. Mohammadi Z, et al. BMC Cardiovasc Disord. 2024 Nov 13;24(1):641. doi: 10.1186/s12872-024-04318-8. BMC Cardiovasc Disord. 2024. PMID: 39538180 Free PMC article.
In a meta-analysis of three trials that reported troponin T levels, we found a significant impact of L-arginine on reducing troponin T levels (WMD = -0.61 ng/ml; 95% CI: -1.07, -0.15). Our analysis also showed that L-arginine had a noticeable impact on decreasing in …
In a meta-analysis of three trials that reported troponin T levels, we found a significant impact of L-arginine on reducing troponin …
2,894 results