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Year Number of Results
1969 1
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1990 1
1991 2
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1993 3
1994 14
1995 12
1996 8
1997 14
1998 12
1999 23
2000 11
2001 21
2002 11
2003 19
2004 21
2005 21
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2007 21
2008 20
2009 28
2010 22
2011 31
2012 22
2013 18
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455 results

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Page 1
The Potential Role of Arginine Supplements on Erectile Dysfunction: A Systemic Review and Meta-Analysis.
Rhim HC, Kim MS, Park YJ, Choi WS, Park HK, Kim HG, Kim A, Paick SH. Rhim HC, et al. J Sex Med. 2019 Feb;16(2):223-234. doi: 10.1016/j.jsxm.2018.12.002. J Sex Med. 2019. PMID: 30770070
INTRODUCTION: The efficacy and safety of arginine supplements in erectile dysfunction (ED) remain debatable. AIM: To assess the potential role of arginine supplements on ED as alternatives to phosphodiesterase inhibitors. ...Arginine supplements also c …
INTRODUCTION: The efficacy and safety of arginine supplements in erectile dysfunction (ED) remain debatable. AIM: To assess th …
Nitric oxide synthases: regulation and function.
Förstermann U, Sessa WC. Förstermann U, et al. Eur Heart J. 2012 Apr;33(7):829-37, 837a-837d. doi: 10.1093/eurheartj/ehr304. Epub 2011 Sep 1. Eur Heart J. 2012. PMID: 21890489 Free PMC article. Review.
Nitrergic nerves are of particular importance in the relaxation of corpus cavernosum and penile erection. Phosphodiesterase 5 inhibitors (sildenafil, vardenafil, and tadalafil) require at least a residual nNOS activity for their action. ...Pharmacologically, vascula …
Nitrergic nerves are of particular importance in the relaxation of corpus cavernosum and penile erection. Phosphodiesterase 5 …
Dietary Supplements for Erectile Dysfunction: Analysis of Marketed Products, Systematic Review, Meta-Analysis and Rational Use.
Petre GC, Francini-Pesenti F, Vitagliano A, Grande G, Ferlin A, Garolla A. Petre GC, et al. Nutrients. 2023 Aug 22;15(17):3677. doi: 10.3390/nu15173677. Nutrients. 2023. PMID: 37686709 Free PMC article.
A systematic review of the literature was performed to evaluate the effect of DS and to detect the active ingredients able to improve erectile function-called effective ingredients (EIs)-and their minimal effective daily dose (mED). A metanalysis identified some nut …
A systematic review of the literature was performed to evaluate the effect of DS and to detect the active ingredients able to improve ere …
Efficacy of L-arginine and Pycnogenol in the treatment of male erectile dysfunction: a systematic review and meta-analysis.
Tian Y, Zhou Q, Li W, Liu M, Li Q, Chen Q. Tian Y, et al. Front Endocrinol (Lausanne). 2023 Oct 4;14:1211720. doi: 10.3389/fendo.2023.1211720. eCollection 2023. Front Endocrinol (Lausanne). 2023. PMID: 37908749 Free PMC article.
BACKGROUND: The objective of this meta-analysis was to review clinical trials of the combination of Pycnogenol and L-arginine (PAL) in the treatment of erectile dysfunction in men and to observe the effect of PAL combined therapy on sexual function in patie …
BACKGROUND: The objective of this meta-analysis was to review clinical trials of the combination of Pycnogenol and L-arginine (PAL) …
Impact of COVID 19 on erectile function.
Adeyemi DH, Odetayo AF, Hamed MA, Akhigbe RE. Adeyemi DH, et al. Aging Male. 2022 Dec;25(1):202-216. doi: 10.1080/13685538.2022.2104833. Aging Male. 2022. PMID: 35924485 Free article. Review.
COVID-19 also induces impaired pulmonary haemodynamics, increased ang II, testicular damage and low serum testosterone, and reduced arginine-dependent NO bioavailability that promotes reactive oxygen species (ROS) generation and endothelial dysfunction, resulting in ED. In …
COVID-19 also induces impaired pulmonary haemodynamics, increased ang II, testicular damage and low serum testosterone, and reduced argin …
Nutraceutical interventions for erectile dysfunction: a systematic review and network meta-analysis.
Barbonetti A, Tienforti D, Antolini F, Spagnolo L, Cavallo F, Di Pasquale AB, Maggi M, Corona G. Barbonetti A, et al. J Sex Med. 2024 Oct 31;21(11):1054-1063. doi: 10.1093/jsxmed/qdae123. J Sex Med. 2024. PMID: 39279185
In the overall NMA, compared to placebo, the combination propionyl L-carnitine (PLC) + acetyl L-carnitine (ALC) + Sildenafil was associated with the highest SUCRA (97%) in improving erectile function score, followed by L-Arginine + Tadalafil (84%), Sildenafil …
In the overall NMA, compared to placebo, the combination propionyl L-carnitine (PLC) + acetyl L-carnitine (ALC) + Sildenafil was associated …
Role of L-Arginine in Nitric Oxide Synthesis and Health in Humans.
Wu G, Meininger CJ, McNeal CJ, Bazer FW, Rhoads JM. Wu G, et al. Adv Exp Med Biol. 2021;1332:167-187. doi: 10.1007/978-3-030-74180-8_10. Adv Exp Med Biol. 2021. PMID: 34251644
As a functional amino acid (AA), L-arginine (Arg) serves not only as a building block of protein but also as an essential substrate for the synthesis of nitric oxide (NO), creatine, polyamines, homoarginine, and agmatine in mammals (including humans). ...Arg and its …
As a functional amino acid (AA), L-arginine (Arg) serves not only as a building block of protein but also as an essential subs …
Erectile Function and Sexual Behavior: A Review of the Role of Nitric Oxide in the Central Nervous System.
Melis MR, Argiolas A. Melis MR, et al. Biomolecules. 2021 Dec 11;11(12):1866. doi: 10.3390/biom11121866. Biomolecules. 2021. PMID: 34944510 Free PMC article. Review.
Nitric oxide (NO), the neuromodulator/neurotransmitter formed from l-arginine by neuronal, endothelial and inducible NO synthases, is involved in numerous functions across the body, from the control of arterial blood pressure to penile erection, and at …
Nitric oxide (NO), the neuromodulator/neurotransmitter formed from l-arginine by neuronal, endothelial and inducible NO synthases, is …
Plant-Based Diet and Erectile Dysfunction: A Narrative Review.
Jiménez MDCF. Jiménez MDCF. J Nutr. 2025 Jun;155(6):1644-1652. doi: 10.1016/j.tjnut.2025.04.019. Epub 2025 Apr 22. J Nutr. 2025. PMID: 40274235 Free article. Review.
Evidence shows that the consumption of plant foods, particularly those in their whole form (fruits, vegetables, whole grains, nuts, seeds, and legumes from which no edible part has been removed), improves cardiometabolic risk factors and is associated with reduced risk of cardiov …
Evidence shows that the consumption of plant foods, particularly those in their whole form (fruits, vegetables, whole grains, nuts, seeds, a …
Nitric oxide and penile erectile function.
Toda N, Ayajiki K, Okamura T. Toda N, et al. Pharmacol Ther. 2005 May;106(2):233-66. doi: 10.1016/j.pharmthera.2004.11.011. Epub 2005 Mar 2. Pharmacol Ther. 2005. PMID: 15866322 Review.
NO from nerves and possibly endothelia plays a crucial role in initiating and maintaining intracavernous pressure increase, penile vasodilatation, and penile erection that are dependent on cyclic GMP synthesized with activation of soluble guanylyl cyclase by …
NO from nerves and possibly endothelia plays a crucial role in initiating and maintaining intracavernous pressure increase, penile va …
455 results