Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1964 1
1967 1
1972 1
1973 1
1974 1
1975 4
1976 2
1977 2
1978 3
1979 3
1980 1
1981 1
1982 2
1983 8
1985 5
1986 2
1987 1
1988 4
1989 2
1990 2
1991 7
1992 5
1993 14
1994 12
1995 13
1996 18
1997 17
1998 17
1999 20
2000 14
2001 16
2002 20
2003 16
2004 20
2005 19
2006 21
2007 19
2008 21
2009 12
2010 18
2011 14
2012 16
2013 20
2014 18
2015 13
2016 10
2017 15
2018 22
2019 36
2020 38
2021 33
2022 59
2023 62
2024 72
2025 111
2026 70

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

888 results

Results by year

Filters applied: . Clear all
Page 1
Gut microbiota-derived arginine metabolism mitigates intestinal ischemia-reperfusion injury.
Li X, Hou M, Lyu J, Min X, Han X, Wang X, Liu Z, Leng Y. Li X, et al. J Transl Med. 2025 Nov 4;23(1):1215. doi: 10.1186/s12967-025-07225-4. J Transl Med. 2025. PMID: 41188912 Free PMC article.
However, whether the gut microbiota regulates immune homeostasis and mucosal repair through arginine metabolism remains unclear. ...CONCLUSIONS: The gut microbiota functions as an upstream regulator of arginine metabolism during I/R injury. ...
However, whether the gut microbiota regulates immune homeostasis and mucosal repair through arginine metabolism remains unclea …
Crataegus pinnatifida polysaccharide alleviates DSS-induced colitis in mice by regulating the intestinal microbiota and enhancing arginine biosynthesis.
Wei FH, Xie WY, Zhao PS, Ji ZH, Gao F, Chen CZ, Zhang Z, Gao W, Yuan B. Wei FH, et al. Phytomedicine. 2025 Jul;142:156794. doi: 10.1016/j.phymed.2025.156794. Epub 2025 Apr 20. Phytomedicine. 2025. PMID: 40315641
Mechanistically, CPP indirectly promoted the expression of the rate-limiting enzyme argininosuccinate synthase 1 (ASS1) in the intestinal Arginine biosynthesis pathway by reshaping the intestinal microbiota, thereby increasing intestinal Arginine …
Mechanistically, CPP indirectly promoted the expression of the rate-limiting enzyme argininosuccinate synthase 1 (ASS1) in the intestinal …
Bone Broth Benefits: How Its Nutrients Fortify Gut Barrier in Health and Disease.
Matar A, Abdelnaem N, Camilleri M. Matar A, et al. Dig Dis Sci. 2025 Jun;70(6):1951-1961. doi: 10.1007/s10620-025-08997-x. Epub 2025 Apr 3. Dig Dis Sci. 2025. PMID: 40180691 Review.
This review investigates the nutritional components of bone broth, focusing primarily on the most abundant amino acids and minerals saturated in bone broth and their impact on health, particularly in the context of intestinal barrier integrity, intestinal permeabili …
This review investigates the nutritional components of bone broth, focusing primarily on the most abundant amino acids and minerals saturate …
Intestinal TLR4 deletion exacerbates acute pancreatitis through gut microbiota dysbiosis and Paneth cells deficiency.
Qi-Xiang M, Yang F, Ze-Hua H, Nuo-Ming Y, Rui-Long W, Bin-Qiang X, Jun-Jie F, Chun-Lan H, Yue Z. Qi-Xiang M, et al. Gut Microbes. 2022 Jan-Dec;14(1):2112882. doi: 10.1080/19490976.2022.2112882. Gut Microbes. 2022. PMID: 35982604 Free PMC article.
Toll-like receptor 4 (TLR4) has been identified as a potentially promising therapeutic target in acute pancreatitis (AP). However, the role of intestinal TLR4 in AP and AP-associated gut injury remains unclear. This study aimed to explore the relationship between …
Toll-like receptor 4 (TLR4) has been identified as a potentially promising therapeutic target in acute pancreatitis (AP). However, the role …
Enterococci enhance Clostridioides difficile pathogenesis.
Smith AB, Jenior ML, Keenan O, Hart JL, Specker J, Abbas A, Rangel PC, Di C, Green J, Bustin KA, Gaddy JA, Nicholson MR, Laut C, Kelly BJ, Matthews ML, Evans DR, Van Tyne D, Furth EE, Papin JA, Bushman FD, Erlichman J, Baldassano RN, Silverman MA, Dunny GM, Prentice BM, Skaar EP, Zackular JP. Smith AB, et al. Nature. 2022 Nov;611(7937):780-786. doi: 10.1038/s41586-022-05438-x. Epub 2022 Nov 16. Nature. 2022. PMID: 36385534 Free PMC article.
Through a parallel process of nutrient restriction and cross-feeding, enterococci shape the metabolic environment in the gut and reprogramme C. difficile metabolism. Enterococci provide fermentable amino acids, including leucine and ornithine, which increase C. difficile f …
Through a parallel process of nutrient restriction and cross-feeding, enterococci shape the metabolic environment in the gut and repr …
Gut microbiota contributes to protection against porcine deltacoronavirus infection in piglets by modulating intestinal barrier and microbiome.
Zhang Y, Si L, Shu X, Qiu C, Wan X, Li H, Ma S, Jin X, Wei Z, Hu H. Zhang Y, et al. Microbiome. 2025 Apr 7;13(1):93. doi: 10.1186/s40168-025-02092-z. Microbiome. 2025. PMID: 40189556 Free PMC article.
BACKGROUND: Gut microbiota plays a critical role in counteracting enteric viral infection. Our previous study demonstrated that infection of porcine deltacoronavirus (PDCoV) disturbs gut microbiota and causes intestinal damage and inflammation in piglets. ... …
BACKGROUND: Gut microbiota plays a critical role in counteracting enteric viral infection. Our previous study demonstrated that infec …
Intestinal neutrophil extracellular traps promote gut barrier damage exacerbating endotoxaemia, systemic inflammation and progression of diabetic retinopathy in type 2 diabetes.
Floyd JL, Prasad R, Dupont MD, Adu-Rutledge Y, Anshumali S, Paul S, Li Calzi S, Qi X, Malepati A, Johnson E, Jumbo-Lucioni P, Crosson JN, Mason JO 3rd, Boulton ME, Welner RS, Grant MB. Floyd JL, et al. Diabetologia. 2025 Apr;68(4):866-889. doi: 10.1007/s00125-024-06349-4. Epub 2025 Jan 28. Diabetologia. 2025. PMID: 39875729 Free PMC article.
Here, we interrogate the relationship between gut barrier dysfunction, endotoxaemia and systemic and intestinal neutrophilia in diabetic retinopathy. ...The db/db mice exhibited an increase in stem-like pre-neutrophils in the intestine and bone marrow and a d …
Here, we interrogate the relationship between gut barrier dysfunction, endotoxaemia and systemic and intestinal neutrophilia i …
Commensal yeast promotes Salmonella Typhimurium virulence.
Jaswal K, Todd OA, Flores Audelo RC, Santus W, Paul S, Duffy CM, Eshoo ET 3rd, Singh M, Miao J, Underhill DM, Peters BM, Behnsen J. Jaswal K, et al. Nature. 2025 Sep;645(8082):1002-1010. doi: 10.1038/s41586-025-09415-y. Epub 2025 Sep 3. Nature. 2025. PMID: 40903573 Free PMC article.
A specific effector, SopB, was sufficient to manipulate C. albicans metabolism and trigger the release of millimolar amounts of arginine into the extracellular environment. The released arginine, in turn, induced expression of the type 3 secretion system in Salmonel …
A specific effector, SopB, was sufficient to manipulate C. albicans metabolism and trigger the release of millimolar amounts of arginine …
L-arginine metabolism ameliorates age-related cognitive impairment by Amuc_1100-mediated gut homeostasis maintaining.
He J, Hou T, Wang Q, Wang Q, Jiang Y, Chen L, Xu J, Qi Y, Jia D, Gu Y, Gao L, Yu Y, Wang L, Kang L, Si J, Wang L, Chen S. He J, et al. Aging Cell. 2024 Apr;23(4):e14081. doi: 10.1111/acel.14081. Epub 2024 Jan 18. Aging Cell. 2024. PMID: 38236004 Free PMC article.
Impaired L-arginine metabolic homeostasis was associated with low abundance of intestinal Akkermansia muciniphila (AKK) colonization in mice. ...In aged brain, Amuc_1100 promoted the superoxide dismutase to alleviated oxidation stress, and increased nitric oxide, de …
Impaired L-arginine metabolic homeostasis was associated with low abundance of intestinal Akkermansia muciniphila (AKK) coloni …
Neutrophil extracellular traps impair intestinal barrier functions in sepsis by regulating TLR9-mediated endoplasmic reticulum stress pathway.
Sun S, Duan Z, Wang X, Chu C, Yang C, Chen F, Wang D, Wang C, Li Q, Ding W. Sun S, et al. Cell Death Dis. 2021 Jun 11;12(6):606. doi: 10.1038/s41419-021-03896-1. Cell Death Dis. 2021. PMID: 34117211 Free PMC article.
Increased neutrophil extracellular traps (NETs) formation has been found to be associated with intestinal inflammation, and it has been reported that NETs may drive the progression of gut dysregulation in sepsis. ...Furthermore, PAD4 deficiency alleviated intesti …
Increased neutrophil extracellular traps (NETs) formation has been found to be associated with intestinal inflammation, and it has be …
888 results