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Page 1
Aristolone in Nardostachys jatamansi DC. induces mesenteric vasodilation and ameliorates hypertension via activation of the K(ATP) channel and PDK1-Akt-eNOS pathway.
Fang J, Li R, Zhang Y, Oduro PK, Li S, Leng L, Wang Z, Rao Y, Niu L, Wu HH, Wang Q. Fang J, et al. Phytomedicine. 2022 Sep;104:154257. doi: 10.1016/j.phymed.2022.154257. Epub 2022 Jun 9. Phytomedicine. 2022. PMID: 35738117
Finally, (-)-aristolone lowers hypertensive rats' systolic and diastolic blood pressure. ...These findings point to N. jatamansi and aristolone as possible antihypertensive agents....
Finally, (-)-aristolone lowers hypertensive rats' systolic and diastolic blood pressure. ...These findings point to N. jatamansi and …
Optimization of the extraction of the p-menthadienol isomers and aristolone contained in the essential oil from Elyonurus hensii using a 2(3) full factorial design.
Loumouamou AN, Bikindou K, Bitemou E, Chalard P, Silou T, Figueredo G. Loumouamou AN, et al. Food Sci Nutr. 2017 Feb 9;5(3):784-792. doi: 10.1002/fsn3.459. eCollection 2017 May. Food Sci Nutr. 2017. PMID: 28572969 Free PMC article.
The aim of this study was to optimize the extraction of p-menthadienol isomers and aristolone from the essential oil of Elyonurus hensii by hydrodistillation. ...At the root level, the samples that have a very low residual water content provide extracts richer in aristo …
The aim of this study was to optimize the extraction of p-menthadienol isomers and aristolone from the essential oil of Elyonurus hen …
Aristolane-type Sesquiterpenoids from Nardostachys chinensis and Revised Structure of Aristolanhydride.
Wang LX, Jiang XJ, Li XM, Mao MF, Wei GZ, Wang F. Wang LX, et al. Nat Prod Bioprospect. 2019 Apr;9(2):149-155. doi: 10.1007/s13659-019-0200-7. Epub 2019 Mar 8. Nat Prod Bioprospect. 2019. PMID: 30848431 Free PMC article.
Four hitherto unknown aristolane-type sesquiterpenes, including one novel 8,9-secoaristolane, namely secoaristolenedioic acid (1), two aristolone derivatives, namely 1alpha,2beta-dihydroxyaristolone (2), 9-epidebilon (3), and one rare aristolane-chalcone hybrid, namely 3'- …
Four hitherto unknown aristolane-type sesquiterpenes, including one novel 8,9-secoaristolane, namely secoaristolenedioic acid (1), two ar …
Mechanistic Study of Schisandra chinensis Fruit Mixture Based on Network Pharmacology, Molecular Docking and Experimental Validation to Improve the Inflammatory Response of DKD Through AGEs/RAGE Signaling Pathway.
Li H, Dong A, Li N, Ma Y, Zhang S, Deng Y, Chen S, Zhang M. Li H, et al. Drug Des Devel Ther. 2023 Feb 27;17:613-632. doi: 10.2147/DDDT.S395512. eCollection 2023. Drug Des Devel Ther. 2023. PMID: 36875720 Free PMC article.
Molecular docking confirmed the tight binding properties between (+)-aristolone, a core component of SM, and key targets. CONCLUSION: This study reveals that SM improves the inflammatory response of DKD through AGEs/RAGE signaling pathway, thus providing a novel idea for t …
Molecular docking confirmed the tight binding properties between (+)-aristolone, a core component of SM, and key targets. CONCLUSION: …
A Simple and Rapid UPLC-PDA Method for Quality Control of Nardostachys jatamansi.
Zhang W, Nan G, Wu HH, Jiang M, Li TX, Wang M, Gao XM, Zhu Y, Song YS, Wang J, Xu YT. Zhang W, et al. Planta Med. 2018 May;84(8):536-543. doi: 10.1055/s-0043-123655. Epub 2017 Dec 4. Planta Med. 2018. PMID: 29202512
Six of the common peaks (5, 7, 12: , and 16: - 18: ) were identified as desoxo-narchinol A, buddleoside, isonardosinone, nardosinone, kanshone H, and (-)-aristolone, respectively, by phytochemical investigation. Five of the six compounds significantly either enhanced or in …
Six of the common peaks (5, 7, 12: , and 16: - 18: ) were identified as desoxo-narchinol A, buddleoside, isonardosinone, nardosinone, kansho …
Terpenoids from Russula lepida and R. amarissima (Basidiomycota, Russulaceae).
Clericuzio M, Cassino C, Corana F, Vidari G. Clericuzio M, et al. Phytochemistry. 2012 Dec;84:154-9. doi: 10.1016/j.phytochem.2012.07.024. Epub 2012 Aug 30. Phytochemistry. 2012. PMID: 22938994
Four aristolane sesquiterpenes were isolated from the fruiting bodies of Russula lepida and R. amarissima, namely (1R,2S)-1,2-dihydroxyaristolone (6), (2S,11S)-2,12-dihydroxy-aristolone (7), (1R,2S,11S)-1,2,12-trihydroxyaristolone (8), (1S,2S,11S)-1,2,12-trihydroxy-aris …
Four aristolane sesquiterpenes were isolated from the fruiting bodies of Russula lepida and R. amarissima, namely (1R,2S)-1,2-dihydroxyarist …
A novel brominated cuparene-derived sesquiterpene ether from the red alga Laurencia sp.
Su S, Sun WS, Wang B, Cheng W, Liang H, Zhao YY, Zhang QY, Wu J. Su S, et al. J Asian Nat Prod Res. 2010 Oct;12(10):916-20. doi: 10.1080/10286020.2010.506190. J Asian Nat Prod Res. 2010. PMID: 20924905
Besides this, two known sesquiterpenes, (9beta)-aristol-1(10)-en-9-ol (2) and aristolone (3), were also yielded, and aristolone (3) was obtained from Laurencia for the first time. ...
Besides this, two known sesquiterpenes, (9beta)-aristol-1(10)-en-9-ol (2) and aristolone (3), were also yielded, and aristolone …
Anti-inflammatory aromadendrane- and cadinane-type sesquiterpenoids from the South China Sea sponge Acanthella cavernosa.
Shen SM, Yang Q, Zang Y, Li J, Liu X, Guo YW. Shen SM, et al. Beilstein J Org Chem. 2022 Jul 25;18:916-925. doi: 10.3762/bjoc.18.91. eCollection 2022. Beilstein J Org Chem. 2022. PMID: 35957756 Free PMC article.
A plausible biosynthetic pathway of these sesquiterpenoids and their internal correlation were proposed and discussed. In an in vitro bioassay, (+)-aristolone (3) exhibited promising anti-inflammatory activity by the inhibition of LPS-induced TNF-alpha and CCL2 release in …
A plausible biosynthetic pathway of these sesquiterpenoids and their internal correlation were proposed and discussed. In an in vitro bioass …
Sesquiterpenes from the sponge Axinyssa isabela.
Zubía E, Ortega MJ, Carballo JL. Zubía E, et al. J Nat Prod. 2008 Dec;71(12):2004-10. doi: 10.1021/np800465n. J Nat Prod. 2008. PMID: 19007287
In addition, the unusual nitrile-containing sesquiterpene 9 has been synthesized from (+)-aristolone (14). The cytotoxic activity of the compounds isolated has been tested against three human tumor cell lines....
In addition, the unusual nitrile-containing sesquiterpene 9 has been synthesized from (+)-aristolone (14). The cytotoxic activity of …
HPTLC and reverse phase HPLC methods for the simultaneous quantification and in vitro screening of antioxidant potential of isolated sesquiterpenoids from the rhizomes of Cyperus rotundus.
Priya Rani M, Padmakumari KP. Priya Rani M, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Sep 1;904:22-8. doi: 10.1016/j.jchromb.2012.05.042. Epub 2012 Jun 12. J Chromatogr B Analyt Technol Biomed Life Sci. 2012. PMID: 22877740
Three sesquiterpenoids solavetivone, aristolone and nootkatone were isolated from the acetone extract of Cyperus rotundus by silica gel column chromatography and identified by spectral studies. ...Among the three sesquiterpenoids isolated, nootkatone possessed the highest …
Three sesquiterpenoids solavetivone, aristolone and nootkatone were isolated from the acetone extract of Cyperus rotundus by silica g …
24 results