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Page 1
Potential Benefits of Black Chokeberry (Aronia melanocarpa) Fruits and Their Constituents in Improving Human Health.
Ren Y, Frank T, Meyer G, Lei J, Grebenc JR, Slaughter R, Gao YG, Kinghorn AD. Ren Y, et al. Molecules. 2022 Nov 13;27(22):7823. doi: 10.3390/molecules27227823. Molecules. 2022. PMID: 36431924 Free PMC article. Review.
The fruits of Aronia melanocarpa (Aronia berries) have been found to show multiple bioactivities potentially beneficial to human health, including antidiabetic, anti-infective, antineoplastic, antiobesity, and antioxidant activities, as well as heart-, liver-, and n …
The fruits of Aronia melanocarpa (Aronia berries) have been found to show multiple bioactivities potentially beneficial to hum …
Aronia melanocarpa L. fruit peels show anti-cancer effects in preclinical models of breast carcinoma: The perspectives in the chemoprevention and therapy modulation.
Dvorska D, Mazurakova A, Lackova L, Sebova D, Kajo K, Samec M, Brany D, Svajdlenka E, Treml J, Mersakova S, Strnadel J, Adamkov M, Lasabova Z, Biringer K, Mojzis J, Büsselberg D, Smejkal K, Kello M, Kubatka P. Dvorska D, et al. Front Oncol. 2024 Oct 7;14:1463656. doi: 10.3389/fonc.2024.1463656. eCollection 2024. Front Oncol. 2024. PMID: 39435289 Free PMC article.
Additionally, the aronia extract enhanced the responsiveness to epirubicin in both cancer cell lines. CONCLUSION: This study is the first to analyze the antitumor effect of A. melanocarpa in selected models of experimental breast carcinoma in vivo and in vitro. ...I …
Additionally, the aronia extract enhanced the responsiveness to epirubicin in both cancer cell lines. CONCLUSION: This study i …
Triterpene Acid (3-O-p-Coumaroyltormentic Acid) Isolated From Aronia Extracts Inhibits Breast Cancer Stem Cell Formation through Downregulation of c-Myc Protein.
Choi HS, Kim SL, Kim JH, Deng HY, Yun BS, Lee DS. Choi HS, et al. Int J Mol Sci. 2018 Aug 26;19(9):2528. doi: 10.3390/ijms19092528. Int J Mol Sci. 2018. PMID: 30149665 Free PMC article. Review.
Cancer stem cells (CSCs) are drug-resistant and radiation-resistant cancer cells that are responsible for tumor progression and maintenance, cancer recurrence, and metastasis. Targeting breast CSCs with phytochemicals is a new paradigm for cancer preve …
Cancer stem cells (CSCs) are drug-resistant and radiation-resistant cancer cells that are responsible for tumor progression an …
The Anti-Metastatic Potential of Aronia Leaf Extracts on Colon Cancer Cells.
Owczarek K, Caban M, Sosnowska D, Kajszczak D, Lewandowska U. Owczarek K, et al. Nutrients. 2024 Nov 28;16(23):4110. doi: 10.3390/nu16234110. Nutrients. 2024. PMID: 39683504 Free PMC article.
BACKGROUND/OBJECTIVES: Numerous studies have demonstrated the health benefits of polyphenols found in aronia fruits; however, little is known about how aronia leaf polyphenols impact colorectal cancer (CRC). This study aimed to evaluate the in vitro anti-meta …
BACKGROUND/OBJECTIVES: Numerous studies have demonstrated the health benefits of polyphenols found in aronia fruits; however, little …
The anticancer effects of Aronia berry extract are mediated by Chk1 and p53 in colorectal cancer.
Asahi Y, Xu C, Okuno K, Taketomi A, Goel A. Asahi Y, et al. Phytomedicine. 2024 Dec;135:156086. doi: 10.1016/j.phymed.2024.156086. Epub 2024 Sep 19. Phytomedicine. 2024. PMID: 39326133
BACKGROUND: Aronia berry extracts (ABE) have recently been reported to possess significant anti-cancer effects in various malignancies, including colorectal cancer (CRC), due to their high polyphenolic content. However, the molecular mechanism(s) underlying t …
BACKGROUND: Aronia berry extracts (ABE) have recently been reported to possess significant anti-cancer effects in various mali …
Combined treatment with Aronia berry extract and oligomeric proanthocyanidins exhibit a synergistic anticancer efficacy through LMNB1-AKT signaling pathways in colorectal cancer.
Li Y, Xu C, Weng W, Goel A. Li Y, et al. Mol Carcinog. 2024 Nov;63(11):2145-2157. doi: 10.1002/mc.23800. Epub 2024 Sep 16. Mol Carcinog. 2024. PMID: 39282961
Colorectal cancer (CRC) is one of the most prevalent and highly recurrent malignancies worldwide and currently ranks as the second leading cause of cancer-related deaths. ...Recent research indicates that several natural products, including Aronia berry extra …
Colorectal cancer (CRC) is one of the most prevalent and highly recurrent malignancies worldwide and currently ranks as the second le …
Aronia Berry Extract Modulates MYD88/NF-kB/P-Glycoprotein Axis to Overcome Gemcitabine Resistance in Pancreatic Cancer.
Li Y, Xu C, Han H, Pascual-Sabater S, Fillat C, Goel A. Li Y, et al. Pharmaceuticals (Basel). 2024 Jul 9;17(7):911. doi: 10.3390/ph17070911. Pharmaceuticals (Basel). 2024. PMID: 39065761 Free PMC article.
Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal disease with poor survival rates, primarily due to the limited effectiveness of gemcitabine (Gem)-based chemotherapy, as well as the acquisition of chemotherapeutic resistance. Aronia berry extracts (ABEs), abundan …
Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal disease with poor survival rates, primarily due to the limited effectiveness of g …
Antioxidant Properties of Aronia melanocarpa and Morinda citrifolia Juices and their Impact on Bladder Cancer Cell Lines.
Nowak D, Kloskowski T, Gośliński M, Buhl M, Wojtowicz E, Popławski C, Drewa T, Pokrywczyńska M. Nowak D, et al. Med Sci Monit. 2025 Mar 9;31:e945120. doi: 10.12659/MSM.945120. Med Sci Monit. 2025. PMID: 40057821 Free PMC article.
The results showed that Aronia and Noni samples were significantly more cytotoxic to urinary bladder cancer cells than to normal cells. ...CONCLUSIONS The results are promising and could indicate that Aronia and Noni juices exert beneficial effects against bl …
The results showed that Aronia and Noni samples were significantly more cytotoxic to urinary bladder cancer cells than to norm …
Catechol derived from aronia juice through lactic acid bacteria fermentation inhibits breast cancer stem cell formation via modulation Stat3/IL-6 signaling pathway.
Choi HS, Kim JH, Kim SL, Deng HY, Lee D, Kim CS, Yun BS, Lee DS. Choi HS, et al. Mol Carcinog. 2018 Nov;57(11):1467-1479. doi: 10.1002/mc.22870. Epub 2018 Jul 18. Mol Carcinog. 2018. PMID: 29964299
Cancer stem cells (CSCs) as a subpopulation of cancer cells are drug-resistant and radiation-resistant cancer cells to be responsible for tumor progress, maintenance and recurrence of cancer, and metastasis. This study isolated and investigated a new …
Cancer stem cells (CSCs) as a subpopulation of cancer cells are drug-resistant and radiation-resistant cancer cells to …
Cytotoxicity of gemcitabine enhanced by polyphenolics from Aronia melanocarpa in pancreatic cancer cell line AsPC-1.
Thani NA, Keshavarz S, Lwaleed BA, Cooper AJ, Rooprai HK. Thani NA, et al. J Clin Pathol. 2014 Nov;67(11):949-54. doi: 10.1136/jclinpath-2013-202075. Epub 2014 Sep 17. J Clin Pathol. 2014. PMID: 25232128
Pancreatic cancer was chosen as a target, as its prognosis remains dismal despite advances in therapy. ...CONCLUSIONS: The implication of this study, using single cancer cell line, is that chemotherapy (at least with gemcitabine) might be usefully augmented with the …
Pancreatic cancer was chosen as a target, as its prognosis remains dismal despite advances in therapy. ...CONCLUSIONS: The implicatio …
65 results