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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1991 3
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1994 7
1995 3
1996 6
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1998 12
1999 10
2000 8
2001 15
2002 13
2003 20
2004 20
2005 31
2006 21
2007 31
2008 37
2009 38
2010 38
2011 26
2012 42
2013 23
2014 37
2015 26
2016 29
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2025 13
2026 6

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601 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Pyronaridine-artesunate for treating uncomplicated Plasmodium falciparum malaria.
Pryce J, Hine P. Pryce J, et al. Cochrane Database Syst Rev. 2019 Jan 8;1(1):CD006404. doi: 10.1002/14651858.CD006404.pub3. Cochrane Database Syst Rev. 2019. Update in: Cochrane Database Syst Rev. 2022 Jun 21;6:CD006404. doi: 10.1002/14651858.CD006404.pub4. PMID: 30620055 Free PMC article. Updated.
Concerns about artemisinin resistance have led to global initiatives to develop new partner drugs to protect artemisinin derivatives in ACT. Pyronaridine-artesunate is a novel ACT. OBJECTIVES: To evaluate the efficacy of pyronaridine-artesunate compared to alternati …
Concerns about artemisinin resistance have led to global initiatives to develop new partner drugs to protect artemisinin derivatives in ACT. …
Pyronaridine-artesunate for treating uncomplicated Plasmodium falciparum malaria.
Fox T, Otieno JA, Pryce J, Hine P. Fox T, et al. Cochrane Database Syst Rev. 2025 Oct 14;10(10):CD006404. doi: 10.1002/14651858.CD006404.pub5. Cochrane Database Syst Rev. 2025. PMID: 41085194
Acceptability and feasibility One study determined that the adherence rate to a three-day treatment with pyronaridine-artesunate in children aged under five years was 85.3%. Limited qualitative data suggests pyronaridine-artesunate is acceptable to patients and thei …
Acceptability and feasibility One study determined that the adherence rate to a three-day treatment with pyronaridine-artesunate in c …
Artesunate-mefloquine therapy for uncomplicated Plasmodium falciparum malaria: an updated systematic review and meta-analysis of efficacy and safety.
de Freitas BS, Fernandes GH, Pereira ACEDS, Peixoto HM. de Freitas BS, et al. Trans R Soc Trop Med Hyg. 2024 Feb 1;118(2):84-94. doi: 10.1093/trstmh/trad069. Trans R Soc Trop Med Hyg. 2024. PMID: 37772768
To provide a continuous update on the safety and efficacy of artesunate-mefloquine (ASMQ) compared with other artemisinin combination therapy (ACT) schemes used in the treatment of uncomplicated malaria caused by Plasmodium falciparum, this study updated and expanded the r …
To provide a continuous update on the safety and efficacy of artesunate-mefloquine (ASMQ) compared with other artemisinin combination …
Artesunate, imatinib, and infliximab in COVID-19: A rapid review and meta-analysis of current evidence.
Amani B, Zareei S, Amani B, Zareei M, Zareei N, Shabestan R, Akbarzadeh A. Amani B, et al. Immun Inflamm Dis. 2022 Jun;10(6):e628. doi: 10.1002/iid3.628. Immun Inflamm Dis. 2022. PMID: 35634954 Free PMC article. Review.
The purpose of the present study is to seek available evidence for the efficacy and safety of three promising medications artesunate, imatinib, and infliximab against COVID-19. METHODS: A literature search was conducted in PubMed, Cochrane Library, medRxive, and Google Sch …
The purpose of the present study is to seek available evidence for the efficacy and safety of three promising medications artesunate, …
Artesunate plus pyronaridine for treating uncomplicated Plasmodium falciparum malaria.
Bukirwa H, Unnikrishnan B, Kramer CV, Sinclair D, Nair S, Tharyan P. Bukirwa H, et al. Cochrane Database Syst Rev. 2014 Mar 4;(3):CD006404. doi: 10.1002/14651858.CD006404.pub2. Cochrane Database Syst Rev. 2014. Update in: Cochrane Database Syst Rev. 2019 Jan 08;1:CD006404. doi: 10.1002/14651858.CD006404.pub3. PMID: 24596021 Free PMC article. Updated.
Artesunate-pyronaridine versus artesunate plus mefloquineIn one multicentre trial, enrolling mainly older children and adults from South East Asia, both artesunate-pyronaridine and artesunate plus mefloquine had fewer than 5% PCR adjusted treatment fai …
Artesunate-pyronaridine versus artesunate plus mefloquineIn one multicentre trial, enrolling mainly older children and adults …
Artesunate combinations for treatment of malaria: meta-analysis.
Adjuik M, Babiker A, Garner P, Olliaro P, Taylor W, White N; International Artemisinin Study Group. Adjuik M, et al. Lancet. 2004 Jan 3;363(9402):9-17. doi: 10.1016/s0140-6736(03)15162-8. Lancet. 2004. PMID: 14723987
Parasite clearance was significantly faster (rate ratio 1.98, 95% CI 1.85-2.12, n=3517) with artesunate. In participants with no gametocytes at baseline, artesunate reduced gametocyte count on day 7 (OR 0.11, 95% CI 0.09-0.15, n=2734), with larger effects at days 14 …
Parasite clearance was significantly faster (rate ratio 1.98, 95% CI 1.85-2.12, n=3517) with artesunate. In participants with no game …
Artesunate versus quinine for treating severe malaria.
Sinclair D, Donegan S, Isba R, Lalloo DG. Sinclair D, et al. Cochrane Database Syst Rev. 2012 Jun 13;2012(6):CD005967. doi: 10.1002/14651858.CD005967.pub4. Cochrane Database Syst Rev. 2012. PMID: 22696354 Free PMC article.
This review examines whether treatment with artesunate, instead of the standard treatment quinine, would result in fewer deaths and better treatment outcomes. ...AUTHORS' CONCLUSIONS: The evidence clearly supports the superiority of parenteral artesunate over quinin …
This review examines whether treatment with artesunate, instead of the standard treatment quinine, would result in fewer deaths and b …
Artesunate, artemether or quinine in severe Plasmodium falciparum malaria?
Checkley AM, Whitty CJ. Checkley AM, et al. Expert Rev Anti Infect Ther. 2007 Apr;5(2):199-204. doi: 10.1586/14787210.5.2.199. Expert Rev Anti Infect Ther. 2007. PMID: 17402835 Review.
The South East Asian Quinine Artesunate Malaria Trial (SEAQUAMAT), a multicenter, randomized, open-label trial in 1461 adults with severe malaria in Asia compared artesunate with quinine. Mortality was 15% in the artesunate group and 22% in the quinine group, …
The South East Asian Quinine Artesunate Malaria Trial (SEAQUAMAT), a multicenter, randomized, open-label trial in 1461 adults with se …
Artesunate versus quinine for treating severe malaria.
Jones KL, Donegan S, Lalloo DG. Jones KL, et al. Cochrane Database Syst Rev. 2007 Oct 17;(4):CD005967. doi: 10.1002/14651858.CD005967.pub2. Cochrane Database Syst Rev. 2007. Update in: Cochrane Database Syst Rev. 2011 Mar 16;(3):CD005967. doi: 10.1002/14651858.CD005967.pub3. PMID: 17943870 Updated.
We sought evidence of superiority of artesunate compared with the standard treatment quinine. OBJECTIVES: To compare artesunate with quinine for treating severe malaria. ...This review did not identify sufficient data to make firm conclusions about the treatment of …
We sought evidence of superiority of artesunate compared with the standard treatment quinine. OBJECTIVES: To compare artesunate …
601 results