Human endogenous retrovirus-K contributes to motor neuron disease.
Sci Transl Med. 2015 Sep 30;7(307):307ra153. doi: 10.1126/scitranslmed.aac8201.
Sci Transl Med. 2015.
PMID: 26424568
Free PMC article.
The virus was expressed in cortical and spinal neurons of ALS patients, but not in neurons from control healthy individuals. Expression of HERV-K or its env protein in human neurons caused retraction and beading of neurites. ...Thus, HERV-K expression …
The virus was expressed in cortical and spinal neurons of ALS patients, but not in neurons from control healthy individuals. Expression of …