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Growth hormone-releasing peptides.
Ghigo E, Arvat E, Muccioli G, Camanni F. Ghigo E, et al. Eur J Endocrinol. 1997 May;136(5):445-60. doi: 10.1530/eje.0.1360445. Eur J Endocrinol. 1997. PMID: 9186261 Review.
More recently, a heptapeptide, GHRP-1, and two other hexapeptides, GHRP-2 and Hexarelin, have been synthesized and are now available for human studies. Moreover, non-peptidyl GHRP mimetics have been developed which act via GHRP receptors and their effects have been …
More recently, a heptapeptide, GHRP-1, and two other hexapeptides, GHRP-2 and Hexarelin, have been synthesized and are now ava …
Tyr-Ala-Hexarelin, a synthetic octapeptide, possesses the same endocrine activities of Hexarelin and GHRP-2 in humans.
Arvat E, Di Vito L, Lanfranco F, Broglio F, Giordano R, Benso A, Muccioli GP, Deghenghi R, Ghigo E. Arvat E, et al. J Endocrinol Invest. 1999 Feb;22(2):91-7. doi: 10.1007/BF03350886. J Endocrinol Invest. 1999. PMID: 10195374 Clinical Trial.
Also the mean Tmax of the endocrine responses to HEX, GHRP-2 and Tyr-Ala-HEX were similar. In conclusion, the present results demonstrate that in humans Tyr-Ala-HEX is a GH secretagogue as potent as HEX and GHRP-2, two GHRP-6 superanalogs. Tyr-Ala-HEX …
Also the mean Tmax of the endocrine responses to HEX, GHRP-2 and Tyr-Ala-HEX were similar. In conclusion, the present results …
Growth hormone-releasing peptides and their analogs.
Camanni F, Ghigo E, Arvat E. Camanni F, et al. Front Neuroendocrinol. 1998 Jan;19(1):47-72. doi: 10.1006/frne.1997.0158. Front Neuroendocrinol. 1998. PMID: 9465289 Review.
Growth hormone-releasing peptides (GHRPs) are a series of hepta (GHRP-1)- and hexapeptides (GHRP-2, GHRP-6, Hexarelin) that have been shown to be effective releasers of GH in animals and humans. ...
Growth hormone-releasing peptides (GHRPs) are a series of hepta (GHRP-1)- and hexapeptides (GHRP-2, GHRP-6, Hexarelin) …
Effects of GHRP-2 and hexarelin, two synthetic GH-releasing peptides, on GH, prolactin, ACTH and cortisol levels in man. Comparison with the effects of GHRH, TRH and hCRH.
Arvat E, di Vito L, Maccagno B, Broglio F, Boghen MF, Deghenghi R, Camanni F, Ghigo E. Arvat E, et al. Peptides. 1997;18(6):885-91. doi: 10.1016/s0196-9781(97)00016-8. Peptides. 1997. PMID: 9285939

In young adults 1 microgram/kg i.v. GHRP-2 and HEX induced a similar, strong GH response, which was higher (p < 0.05) than that to GHRH. ...In young adults, the PRL responses to all doses of GHRP-2 or HEX were similar and lower (p < 0.01) respons

…

In young adults 1 microgram/kg i.v. GHRP-2 and HEX induced a similar, strong GH response, which was higher (p < 0.05) than

…
Orally active growth hormone secretagogues: state of the art and clinical perspectives.
Ghigo E, Arvat E, Camanni F. Ghigo E, et al. Ann Med. 1998 Apr;30(2):159-68. doi: 10.3109/07853899808999399. Ann Med. 1998. PMID: 9667794 Review.
More recently, peptidyl superanalogues GHRP-1, GHRP-2 and hexarelin, and nonpeptidyl mimetics, such as the spiroindoline derivative MK-677, have been synthesized and their effects have been studied in humans. ...
More recently, peptidyl superanalogues GHRP-1, GHRP-2 and hexarelin, and nonpeptidyl mimetics, such as the spiroindoline deriv …