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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1966 1
1968 1
1969 1
1971 2
1972 3
1973 4
1974 3
1975 5
1976 6
1977 4
1978 3
1979 7
1980 1
1981 6
1982 8
1983 7
1984 9
1985 4
1986 5
1987 7
1988 4
1989 5
1990 4
1991 11
1992 13
1993 21
1994 23
1995 28
1996 24
1997 38
1998 33
1999 51
2000 54
2001 57
2002 72
2003 81
2004 94
2005 99
2006 93
2007 67
2008 81
2009 82
2010 89
2011 101
2012 90
2013 108
2014 109
2015 96
2016 86
2017 62
2018 67
2019 69
2020 75
2021 89
2022 101
2023 69
2024 85
2025 61

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2,201 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Ascorbic acid for the treatment of Charcot-Marie-Tooth disease.
Gess B, Baets J, De Jonghe P, Reilly MM, Pareyson D, Young P. Gess B, et al. Cochrane Database Syst Rev. 2015 Dec 11;2015(12):CD011952. doi: 10.1002/14651858.CD011952. Cochrane Database Syst Rev. 2015. PMID: 26662471 Free PMC article.
MAIN RESULTS: Six RCTs compared the effect of oral ascorbic acid (1 to 4 grams) and placebo treatment in CMT1A. In five trials involving adults with CMT1A, a total of 622 participants received ascorbic acid or placebo. ...Meta-analyses of other seconda …
MAIN RESULTS: Six RCTs compared the effect of oral ascorbic acid (1 to 4 grams) and placebo treatment in CMT1A. In five trials …
Steroid, ascorbic acid, and thiamine in adults with sepsis and septic shock: a systematic review and component network meta-analysis.
Fong KM, Au SY, Ng GWY. Fong KM, et al. Sci Rep. 2021 Aug 4;11(1):15777. doi: 10.1038/s41598-021-95386-9. Sci Rep. 2021. PMID: 34349184 Free PMC article.
The use of glucocorticoid or the combination of glucocorticoid, ascorbic acid and thiamine hastened resolution of shock. Component NMA showed glucocorticoid (MD - 0.96, 95% CI - 1.61 to - 0.30) but not ascorbic acid or thiamine shortened the time to re …
The use of glucocorticoid or the combination of glucocorticoid, ascorbic acid and thiamine hastened resolution of shock. Compo …
Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis.
Assouline B, Faivre A, Verissimo T, Sangla F, Berchtold L, Giraud R, Bendjelid K, Sgardello S, Elia N, Pugin J, de Seigneux S, Legouis D. Assouline B, et al. Crit Care Med. 2021 Dec 1;49(12):2112-2120. doi: 10.1097/CCM.0000000000005262. Crit Care Med. 2021. PMID: 34582409
In 2017, a retrospective before/after study reported promising results using a combination of thiamine, ascorbic acid, and hydrocortisone called "metabolic resuscitation cocktail" and several randomized controlled trials assessing its effectiveness were performed. . …
In 2017, a retrospective before/after study reported promising results using a combination of thiamine, ascorbic acid, and hyd …
Efficacy and Safety of Hydrocortisone, Ascorbic Acid, and Thiamine Combination Therapy for the Management of Sepsis and Septic Shock: A Systematic Review and Meta-Analysis of Randomised Controlled Trials.
Deng J, Zuo QK, Venugopal K, Hung J, Zubair A, Blais S, Porter V, Moskalyk M, Heybati K. Deng J, et al. Int Arch Allergy Immunol. 2024;185(10):997-1018. doi: 10.1159/000538959. Epub 2024 Jun 13. Int Arch Allergy Immunol. 2024. PMID: 38870923 Free PMC article.
INTRODUCTION: This systematic review aimed to assess the efficacy and safety of hydrocortisone, ascorbic acid, and thiamine (HAT) combination therapy in patients with sepsis and septic shock. ...
INTRODUCTION: This systematic review aimed to assess the efficacy and safety of hydrocortisone, ascorbic acid, and thiamine (H …
Effect of Ascorbic Acid on Mineral and Bone Disorders in Hemodialysis Patients: a Systematic Review and Meta-Analysis.
Ke G, Huang J, Zhu Y, Yang J, Zhang Y, Chen L, Hu J, Tao S, Hu Y, Yang D, Liu S. Ke G, et al. Kidney Blood Press Res. 2018;43(5):1459-1471. doi: 10.1159/000493661. Epub 2018 Sep 24. Kidney Blood Press Res. 2018. PMID: 30248670 Free article.
BACKGROUND/AIMS: Hemodialysis (HD) patients often have inadequate nutrition, especially with respect to ascorbic acid (AA). It is reported that every HD session may cause a 50%- 75% decrease in plasma AA levels. ...
BACKGROUND/AIMS: Hemodialysis (HD) patients often have inadequate nutrition, especially with respect to ascorbic acid (AA). It …
N-acetylcysteine versus ascorbic acid or N-acetylcysteine plus ascorbic acid in preventing contrast-induced nephropathy: A meta-analysis.
Feng Y, Huang X, Li L, Chen Z. Feng Y, et al. Nephrology (Carlton). 2018 Jun;23(6):530-538. doi: 10.1111/nep.13068. Nephrology (Carlton). 2018. PMID: 28452187 Review.
AIM: The purpose of the present study was to evaluate the efficacy of N-acetylcysteine (NAC) versus ascorbic acid (VC) or NAC plus (+) VC on the prevention of contrast-induced nephropathy (CIN) in patients undergoing contrast administration. ...
AIM: The purpose of the present study was to evaluate the efficacy of N-acetylcysteine (NAC) versus ascorbic acid (VC) or NAC …
Ascorbic acid for anemia management in hemodialysis patients: a systematic review and meta-analysis.
Deved V, Poyah P, James MT, Tonelli M, Manns BJ, Walsh M, Hemmelgarn BR; Alberta Kidney Disease Network. Deved V, et al. Am J Kidney Dis. 2009 Dec;54(6):1089-97. doi: 10.1053/j.ajkd.2009.06.040. Epub 2009 Sep 23. Am J Kidney Dis. 2009. PMID: 19783342
BACKGROUND: Ascorbic acid is believed to improve anemia in patients with end-stage renal disease, but its overall effectiveness is unclear. ...SELECTION CRITERIA FOR STUDIES: Randomized clinical trials of ascorbic acid use in addition to standard anemi …
BACKGROUND: Ascorbic acid is believed to improve anemia in patients with end-stage renal disease, but its overall effectivenes …
Meta-analysis of ascorbic acid for prevention of postoperative atrial fibrillation after cardiac surgery.
Baker WL, Coleman CI. Baker WL, et al. Am J Health Syst Pharm. 2016 Dec 15;73(24):2056-2066. doi: 10.2146/ajhp160066. Epub 2016 Nov 2. Am J Health Syst Pharm. 2016. PMID: 27806938
PURPOSE: Results of a systematic review and meta-analysis of published data on use of ascorbic acid to prevent postoperative atrial fibrillation (POAF) after cardiac surgery are presented. ...RESULTS: The 11 identified studies involved patients receiving coronary ar …
PURPOSE: Results of a systematic review and meta-analysis of published data on use of ascorbic acid to prevent postoperative a …
Malaria Is Associated with Diminished Levels of Ascorbic Acid: A Systematic Review and Meta-Analysis.
Kotepui M, Mahittikorn A, Anabire NG, Masangkay FR, Kotepui KU. Kotepui M, et al. Antioxid Redox Signal. 2024 Mar;40(7-9):460-469. doi: 10.1089/ars.2023.0306. Epub 2023 Aug 1. Antioxid Redox Signal. 2024. PMID: 37337659
Background: It is still unclear how ascorbic acid levels relate to the pathogenesis of malaria. This systematic review synthesized different ascorbic acid levels in malaria patients with different severity levels of malaria and Plasmodium species. ...C …
Background: It is still unclear how ascorbic acid levels relate to the pathogenesis of malaria. This systematic review synthes …
Ascorbic Acid may Exacerbate Aspirin-Induced Increase in Intestinal Permeability.
Sequeira IR, Kruger MC, Hurst RD, Lentle RG. Sequeira IR, et al. Basic Clin Pharmacol Toxicol. 2015 Sep;117(3):195-203. doi: 10.1111/bcpt.12388. Epub 2015 Mar 4. Basic Clin Pharmacol Toxicol. 2015. PMID: 25641731 Free article. Clinical Trial.
Ascorbic acid in combination with aspirin has been used to prevent aspirin-induced oxidative GI damage. ...The excretion of lactulose over the 6-hr period was augmented after consumption of either aspirin or ascorbic acid compared with that after consu …
Ascorbic acid in combination with aspirin has been used to prevent aspirin-induced oxidative GI damage. ...The excretion of la …
2,201 results