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Anxiolytic-like effect of asiaticoside in mice.
Chen SW, Wang WJ, Li WJ, Wang R, Li YL, Huang YN, Liang X. Chen SW, et al. Pharmacol Biochem Behav. 2006 Oct;85(2):339-44. doi: 10.1016/j.pbb.2006.08.017. Epub 2006 Oct 23. Pharmacol Biochem Behav. 2006. PMID: 17059844
The putative anxiolytic activity of asiaticoside was examined in male mice by using a number of experimental paradigms of anxiety, with diazepam being as a positive anxiolytic control. ...Thus, these findings indicated that asiaticoside exhibite …
The putative anxiolytic activity of asiaticoside was examined in male mice by using a number of experimental paradigms of a
Neuroprotective effects of Asiaticoside.
Qi FY, Yang L, Tian Z, Zhao MG, Liu SB, An JZ. Qi FY, et al. Neural Regen Res. 2014 Jul 1;9(13):1275-82. doi: 10.4103/1673-5374.137574. Neural Regen Res. 2014. PMID: 25221579 Free PMC article.
In addition, Asiaticoside showed anxiolytic effects in acute and chronic stress animals. ...These experimental findings provide preliminary evidence that during excitotoxicity induced by N-methyl-D-aspartate exposure in cultured cortical neurons, the neuroprotective …
In addition, Asiaticoside showed anxiolytic effects in acute and chronic stress animals. ...These experimental findings provid …
Evaluation of anxiolytic properties of Gotukola--(Centella asiatica) extracts and asiaticoside in rat behavioral models.
Wijeweera P, Arnason JT, Koszycki D, Merali Z. Wijeweera P, et al. Phytomedicine. 2006 Nov;13(9-10):668-76. doi: 10.1016/j.phymed.2006.01.011. Epub 2006 Feb 20. Phytomedicine. 2006. PMID: 16488124
The ayurvedic medicinal plant Gotukola (Centella asiatica) was evaluated for its anxiolytic properties. Specifically, this study assessed the effects of: Gotukola plant materials of different genotypic origin; hexane, ethyl acetate and methanol extracts of Gotukola; and …
The ayurvedic medicinal plant Gotukola (Centella asiatica) was evaluated for its anxiolytic properties. Specifically, this study asse …
Centella asiatica - Phytochemistry and mechanisms of neuroprotection and cognitive enhancement.
Gray NE, Alcazar Magana A, Lak P, Wright KM, Quinn J, Stevens JF, Maier CS, Soumyanath A. Gray NE, et al. Phytochem Rev. 2018 Feb;17(1):161-194. doi: 10.1007/s11101-017-9528-y. Epub 2017 Sep 20. Phytochem Rev. 2018. PMID: 31736679 Free PMC article.
Multiple studies in rodent models, and a limited number of human studies support C. asiatica's traditional reputation as a cognitive enhancer, as well as its anxiolytic and anticonvulsant effects. Neuroprotective effects of C.asiatica are seen in several in vitro models, f …
Multiple studies in rodent models, and a limited number of human studies support C. asiatica's traditional reputation as a cognitive enhance …
Anxiolytic effects of standardized extract of Centella asiatica (ECa 233) after chronic immobilization stress in mice.
Wanasuntronwong A, Tantisira MH, Tantisira B, Watanabe H. Wanasuntronwong A, et al. J Ethnopharmacol. 2012 Sep 28;143(2):579-85. doi: 10.1016/j.jep.2012.07.010. Epub 2012 Jul 24. J Ethnopharmacol. 2012. PMID: 22841896
CONCLUSIONS: The present study demonstrated anxiolytic effect of ECa 233 in both acutely and chronically stressed animals. These effects could be mainly accounted by madecassoside and asiaticoside, suggesting a possible use of ECa 233 for the treatment of both acute …
CONCLUSIONS: The present study demonstrated anxiolytic effect of ECa 233 in both acutely and chronically stressed animals. These effe …