Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1971 1
1973 1
1976 1
1979 1
1980 1
1982 4
1985 1
1986 1
1988 2
1989 2
1990 1
1991 4
1992 8
1993 17
1994 15
1995 20
1996 21
1997 24
1998 37
1999 21
2000 24
2001 20
2002 32
2003 41
2004 37
2005 42
2006 38
2007 34
2008 35
2009 32
2010 32
2011 45
2012 47
2013 41
2014 39
2015 42
2016 41
2017 44
2018 39
2019 26
2020 39
2021 30
2022 31
2023 26
2024 21
2025 13

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

983 results

Results by year

Filters applied: . Clear all
Page 1
Low-Dose Aspirin for PI3K-Altered Localized Colorectal Cancer.
Martling A, Hed Myrberg I, Nilbert M, Grönberg H, Granath F, Eklund M, Öresland T, Iversen LH, Haapamäki C, Janson M, Westberg K, Segelman J, Ersson U, Prytz M, Angenete E, Bergström R, Mayrhofer M, Glimelius B, Lindberg J; ALASCCA Study Group. Martling A, et al. N Engl J Med. 2025 Sep 18;393(11):1051-1064. doi: 10.1056/NEJMoa2504650. N Engl J Med. 2025. PMID: 40961426 Clinical Trial.
BACKGROUND: Aspirin reduces the incidence of colorectal adenoma and colorectal cancer among high-risk persons. ...METHODS: We conducted a double-blind, randomized, placebo-controlled trial involving patients with stage I, II, or III rectal cancer or stage II …
BACKGROUND: Aspirin reduces the incidence of colorectal adenoma and colorectal cancer among high-risk persons. ...METHODS: We …
Adjuvant Aspirin Treatment in PIK3CA-Mutated Colon Cancer Patients: The SAKK 41/13 Prospective Randomized Placebo-Controlled Double-Blind Trial.
Güller U, Hayoz S, Horber D, Jochum W, De Dosso S, Koeberle D, Schacher S, Inauen R, Stahl M, Delaunoit T, Ettrich T, Bodoky G, Michel P, Koessler T, Rothgiesser K, Calmonte S, Joerger M. Güller U, et al. Clin Cancer Res. 2025 Aug 1;31(15):3142-3149. doi: 10.1158/1078-0432.CCR-24-4048. Clin Cancer Res. 2025. PMID: 40067142 Free PMC article. Clinical Trial.
PURPOSE: We assessed the benefit of adjuvant aspirin in patients with resected phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha (PIK3CA)-mutated colon cancer. ...Although results were not statistically significant because of premature st …
PURPOSE: We assessed the benefit of adjuvant aspirin in patients with resected phosphatidylinositol-4,5-bisphosphate 3-kinase catalyt …
Could Aspirin and Diets High in Fiber Act Synergistically to Reduce the Risk of Colon Cancer in Humans?
Pan P, Huang YW, Oshima K, Yearsley M, Zhang J, Yu J, Arnold M, Wang LS. Pan P, et al. Int J Mol Sci. 2018 Jan 6;19(1):166. doi: 10.3390/ijms19010166. Int J Mol Sci. 2018. PMID: 29316620 Free PMC article. Review.
Multiple randomized clinical trials have demonstrated that aspirin offers substantial protection from colon cancer mortality. The lower aspirin doses causing only minimal gastrointestinal disturbance, ideal for long-term use, can achieve only partial a …
Multiple randomized clinical trials have demonstrated that aspirin offers substantial protection from colon cancer mort …
Aspirin enhances the sensitivity of colon cancer cells to cisplatin by abrogating the binding of NF-kappaB to the COX-2 promoter.
Jiang W, Yan Y, Chen M, Luo G, Hao J, Pan J, Hu S, Guo P, Li W, Wang R, Zuo Y, Sun Y, Sui S, Yu W, Pan Z, Zou K, Zheng Z, Deng W, Wu X, Guo W. Jiang W, et al. Aging (Albany NY). 2020 Jan 6;12(1):611-627. doi: 10.18632/aging.102644. Epub 2020 Jan 6. Aging (Albany NY). 2020. PMID: 31905343 Free PMC article.
Here, we explored the possibility of aspirin as an adjuvant drug to boost the anti-cancer effect of cisplatin for colon cancer. We found that aspirin significantly enhanced the cisplatin-mediated inhibitions of cell proliferation, migration and …
Here, we explored the possibility of aspirin as an adjuvant drug to boost the anti-cancer effect of cisplatin for colon …
Colon cancer chemoprevention: clinical development of aspirin as a chemopreventive agent.
Krishnan K, Ruffin MT, Brenner DE. Krishnan K, et al. J Cell Biochem Suppl. 1997;28-29:148-58. J Cell Biochem Suppl. 1997. PMID: 9589361 Review.
These studies have determined the optimal dose of aspirin for future Phase IIa and IIb chemopreventive trials in high-risk cohorts of patients for colon cancer. ...Strategies to improve recruitment of high-risk cohorts have been developed. Phase IIa non-rando …
These studies have determined the optimal dose of aspirin for future Phase IIa and IIb chemopreventive trials in high-risk cohorts of …
Improved Survival With Adjuvant Cyclooxygenase 2 Inhibition in PIK3CA-Activated Stage III Colon Cancer: CALGB/SWOG 80702 (Alliance).
Nowak JA, Twombly T, Ma C, Shi Q, Haruki K, Fujiyoshi K, Väyrynen J, Zhao M, Knight J, Mane S, Shergill A, Kumar P, Couture F, Kuebler P, Krishnamurthi S, Tan B, Philip P, O'Reilly EM, Shields AF, Ogino S, Fuchs CS, Meyerhardt JA. Nowak JA, et al. J Clin Oncol. 2024 Aug 20;42(24):2853-2859. doi: 10.1200/JCO.23.01680. Epub 2024 Jun 18. J Clin Oncol. 2024. PMID: 38889377 Free PMC article. Clinical Trial.
To prospectively test whether adding the COX-2 inhibitor celecoxib to standard adjuvant chemotherapy reduces the risk of recurrence and improves survival, the National Cancer Institute sponsored the CALGB/SWOG 80702 trial (ClinicalTrials.gov identifier: NCT01150045) for pa …
To prospectively test whether adding the COX-2 inhibitor celecoxib to standard adjuvant chemotherapy reduces the risk of recurrence and impr …
Could aspirin really prevent colon cancer?
Baron JA, Greenberg ER. Baron JA, et al. N Engl J Med. 1991 Dec 5;325(23):1644-6. doi: 10.1056/NEJM199112053252309. N Engl J Med. 1991. PMID: 1944453 No abstract available.
[Aspirin and colorectal cancer].
Grancher A, Michel P, Di Fiore F, Sefrioui D. Grancher A, et al. Bull Cancer. 2018 Feb;105(2):171-180. doi: 10.1016/j.bulcan.2017.09.013. Epub 2017 Nov 15. Bull Cancer. 2018. PMID: 29153543 Review. French.
Colorectal cancer is a worldwide public health problem. Aspirin has been identified as a protective factor against the apparition of colorectal cancer. ...However, primary prevention with aspirin should not be a substitute for screening in colorectal …
Colorectal cancer is a worldwide public health problem. Aspirin has been identified as a protective factor against the apparit …
983 results