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Page 1
"Therapeutic uses of natural astaxanthin: An evidence-based review focused on human clinical trials".
Donoso A, González-Durán J, Muñoz AA, González PA, Agurto-Muñoz C. Donoso A, et al. Pharmacol Res. 2021 Apr;166:105479. doi: 10.1016/j.phrs.2021.105479. Epub 2021 Feb 4. Pharmacol Res. 2021. PMID: 33549728 Review.
Benefits on skin and eye health promotion have also been reported, highlighting its potential for the prevention of skin photo-aging and the treatment of eye diseases like glaucoma, cataracts and uveitis. In this review, we summarize and discuss the currently availa …
Benefits on skin and eye health promotion have also been reported, highlighting its potential for the prevention of skin photo-aging …
Astaxanthin (AstaReal( )) Improved Acute and Chronic Digital Eye Strain in Children: A Randomized Double-Blind Placebo-Controlled Trial.
Hecht KA, Marwah M, Wood V, Nishida Y, Bach AE, Gerson J, Hom MM, Schnackenberg J, Raote S, Srivastava S, Negi P, Caston E. Hecht KA, et al. Adv Ther. 2025 Apr;42(4):1811-1833. doi: 10.1007/s12325-025-03125-7. Epub 2025 Feb 27. Adv Ther. 2025. PMID: 40014233 Clinical Trial.
INTRODUCTION: This study assessed the effects of astaxanthin supplementation on chronic and acute digital eye strain in school-aged children (10-14 years) and evaluated its safety. ...CONCLUSION: Astaxanthin supplementation effectively reduced chronic and acu …
INTRODUCTION: This study assessed the effects of astaxanthin supplementation on chronic and acute digital eye strain in school …
Astaxanthin ameliorates benzalkonium chloride-induced dry eye disease through suppressing inflammation and oxidative stress via Keap1-Nrf2/HO-1 signaling pathways.
Liu Z, Li Y, Bao J, Li S, Wen Y, Zhang P, Feng J, Wang Y, Tian L, Jie Y. Liu Z, et al. Animal Model Exp Med. 2025 Jun;8(6):1056-1079. doi: 10.1002/ame2.70000. Epub 2025 Mar 5. Animal Model Exp Med. 2025. PMID: 40045550 Free PMC article.
BACKGROUND: Dry eye disease (DED) predominantly results from elevated tear film osmolarity, which can not only cause ocular inconvenience but may lead to visual impairments, severely compromising patient well-being and exerting substantial economic burdens as well. Asta …
BACKGROUND: Dry eye disease (DED) predominantly results from elevated tear film osmolarity, which can not only cause ocular inconveni …
Health benefits of astaxanthin against age-related diseases of multiple organs: A comprehensive review.
Alugoju P, Krishna Swamy VKD, Anthikapalli NVA, Tencomnao T. Alugoju P, et al. Crit Rev Food Sci Nutr. 2023;63(31):10709-10774. doi: 10.1080/10408398.2022.2084600. Epub 2022 Jun 16. Crit Rev Food Sci Nutr. 2023. PMID: 35708049 Review.
The natural dietary antioxidant supplementation offers substantial pharmacological and therapeutic effects against various disease conditions. Astaxanthin is one such natural carotenoid with superior antioxidant activity than other carotenoids, as well as well as vitamins …
The natural dietary antioxidant supplementation offers substantial pharmacological and therapeutic effects against various disease condition …
Effects of Astaxanthin, Lutein, and Zeaxanthin on Eye-Hand Coordination and Smooth-Pursuit Eye Movement after Visual Display Terminal Operation in Healthy Subjects: A Randomized, Double-Blind Placebo-Controlled Intergroup Trial.
Yoshida K, Sakai O, Honda T, Kikuya T, Takeda R, Sawabe A, Inaba M, Koike C. Yoshida K, et al. Nutrients. 2023 Mar 17;15(6):1459. doi: 10.3390/nu15061459. Nutrients. 2023. PMID: 36986186 Free PMC article. Clinical Trial.
On the other hand, various food ingredients, including astaxanthin, lutein, and zeaxanthin, are known to help improve the eye health of VDT operators. This study aimed to test the hypothesis that the combination of astaxanthin, lutein, and zeaxanthin can prev …
On the other hand, various food ingredients, including astaxanthin, lutein, and zeaxanthin, are known to help improve the eye …
Effects of anthocyanin, astaxanthin, and lutein on eye functions: a randomized, double-blind, placebo-controlled study.
Kizawa Y, Sekikawa T, Kageyama M, Tomobe H, Kobashi R, Yamada T. Kizawa Y, et al. J Clin Biochem Nutr. 2021 Jul;69(1):77-90. doi: 10.3164/jcbn.20-149. Epub 2021 Feb 5. J Clin Biochem Nutr. 2021. PMID: 34376917 Free PMC article.
We examined the effects of a test food containing anthocyanin, astaxanthin, and lutein on the eye function in healthy Japanese adults with eye fatigue after operating visual display terminals. ...The active group showed a significant improvement in the percen …
We examined the effects of a test food containing anthocyanin, astaxanthin, and lutein on the eye function in healthy Japanese …
Benefits and Safety of Astaxanthin in the Treatment of Mild-To-Moderate Dry Eye Disease.
Tian L, Wen Y, Li S, Zhang P, Wang Y, Wang J, Cao K, Du L, Wang N, Jie Y. Tian L, et al. Front Nutr. 2022 Jan 13;8:796951. doi: 10.3389/fnut.2021.796951. eCollection 2021. Front Nutr. 2022. PMID: 35096941 Free PMC article.
Objectives: To evaluate the effect of astaxanthin in the treatment of mild-to-moderate dry eye disease (DED) in middle-aged and elderly patients. ...History of eye diseases, treatment, systemic disease, and medication before the test were recorded. ...
Objectives: To evaluate the effect of astaxanthin in the treatment of mild-to-moderate dry eye disease (DED) in middle-aged an …
Engineered Microalgal Extracellular Vesicles for Enhancing Mitochondrial Homeostasis in Radiodermatitis Prevention.
Cui J, Dong J, Lang Y, Liu X, Qi Y, Zheng Y, Wang R, Hu H, Zhou M. Cui J, et al. ACS Nano. 2025 Aug 5;19(30):27634-27653. doi: 10.1021/acsnano.5c07135. Epub 2025 Jul 22. ACS Nano. 2025. PMID: 40694433
In this study, we isolated extracellular vesicles (EVs) from the natural microalgae Spirulina platensis (SP) and engineered them by loading astaxanthin (AST) into SP-EVs, resulting in the formation of SP-EVs@AST. This engineered system significantly enhanced the solubility …
In this study, we isolated extracellular vesicles (EVs) from the natural microalgae Spirulina platensis (SP) and engineered them by loading …
The effect of astaxanthin on inflammation in hyperosmolarity of experimental dry eye model in vitro and in vivo.
Li H, Li J, Hou C, Li J, Peng H, Wang Q. Li H, et al. Exp Eye Res. 2020 Aug;197:108113. doi: 10.1016/j.exer.2020.108113. Epub 2020 Jun 10. Exp Eye Res. 2020. PMID: 32531188
Hyperosmolarity is pro-inflammatory stress to the ocular surface epithelium associated with dry eye disease (DED). Astaxanthin (AST) is a kind of carotene, which exists in seafood and plays important roles in the amelioration of inflammatory diseases like arterioscl …
Hyperosmolarity is pro-inflammatory stress to the ocular surface epithelium associated with dry eye disease (DED). Astaxanthin …
Astaxanthin activated the SLC7A11/GPX4 pathway to inhibit ferroptosis and enhance autophagy, ameliorating dry eye disease.
Hou C, Xiao J, Wang Y, Pan X, Liu K, Lu K, Wang Q. Hou C, et al. Front Pharmacol. 2024 Aug 19;15:1407659. doi: 10.3389/fphar.2024.1407659. eCollection 2024. Front Pharmacol. 2024. PMID: 39224780 Free PMC article.
Dry eye disease (DED) is a common eye disease in clinical practice. The crucial pathogenesis of DED is that hyperosmolarity activates oxidative stress signaling pathways in corneal epithelial and immune cells and, thus, produces inflammatory molecules. The complex p …
Dry eye disease (DED) is a common eye disease in clinical practice. The crucial pathogenesis of DED is that hyperosmolarity ac …
129 results