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1,025 results

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Astaxanthin activates the Nrf2/Keap1/HO-1 pathway to inhibit oxidative stress and ferroptosis, reducing triphenyl phosphate (TPhP)-induced neurodevelopmental toxicity.
Zhang Q, Luo C, Li Z, Huang W, Zheng S, Liu C, Shi X, Ma Y, Ni Q, Tan W, Peng J, Chen Y, Wu W, Li J, Wu K. Zhang Q, et al. Ecotoxicol Environ Saf. 2024 Feb;271:115960. doi: 10.1016/j.ecoenv.2024.115960. Epub 2024 Jan 13. Ecotoxicol Environ Saf. 2024. PMID: 38219622 Free article.
In this study, we involved zebrafish to explore the new mechanism of TPhP inducing oxidative stress and ferroptosis to promote neurodevelopmental toxicity. The results suggested that TPhP affected the embryonic development, reduced the number of new neurons, and led …
In this study, we involved zebrafish to explore the new mechanism of TPhP inducing oxidative stress and ferroptosis to promote …
Astaxanthin ameliorates inflammation, oxidative stress, and reproductive outcomes in endometriosis patients undergoing assisted reproduction: A randomized, triple-blind placebo-controlled clinical trial.
Rostami S, Alyasin A, Saedi M, Nekoonam S, Khodarahmian M, Moeini A, Amidi F. Rostami S, et al. Front Endocrinol (Lausanne). 2023 Mar 20;14:1144323. doi: 10.3389/fendo.2023.1144323. eCollection 2023. Front Endocrinol (Lausanne). 2023. PMID: 37020589 Free PMC article. Clinical Trial.
PURPOSE: In a randomized, triple-blind, placebo-controlled clinical trial (RCT) including 50 infertile women with endometriosis candidate for assisted reproductive techniques (ART), we studied the effect of Astaxanthin (AST) on pro-inflammatory cytokines, oxidative …
PURPOSE: In a randomized, triple-blind, placebo-controlled clinical trial (RCT) including 50 infertile women with endometriosis candidate fo …
Astaxanthin supplementation mildly reduced oxidative stress and inflammation biomarkers: a systematic review and meta-analysis of randomized controlled trials.
Ma B, Lu J, Kang T, Zhu M, Xiong K, Wang J. Ma B, et al. Nutr Res. 2022 Mar;99:40-50. doi: 10.1016/j.nutres.2021.09.005. Epub 2021 Dec 30. Nutr Res. 2022. PMID: 35091276
A limited number of trials were available for the effects of astaxanthin on other oxidative stress biomarkers. Astaxanthin supplementation appeared to improve superoxide dismutase activity and reduce serum isoprostane concentration in overweight subjec …
A limited number of trials were available for the effects of astaxanthin on other oxidative stress biomarkers. Astax …
Inhibitory Effect of Astaxanthin on Oxidative Stress-Induced Mitochondrial Dysfunction-A Mini-Review.
Kim SH, Kim H. Kim SH, et al. Nutrients. 2018 Aug 21;10(9):1137. doi: 10.3390/nu10091137. Nutrients. 2018. PMID: 30134611 Free PMC article. Review.
Oxidative stress is a major contributor to the pathogenesis of various human diseases as well as to the aging process. ...In this manner astaxanthin maintains mitochondrial integrity under various pathological conditions. In this review, the inhibitory effect …
Oxidative stress is a major contributor to the pathogenesis of various human diseases as well as to the aging process. ...In t …
Astaxanthin in Aquaculture: Enhancing abalone health through oxidative stress management.
Khan F. Khan F. Fish Shellfish Immunol. 2025 Oct;165:110502. doi: 10.1016/j.fsi.2025.110502. Epub 2025 Jun 13. Fish Shellfish Immunol. 2025. PMID: 40518029 Review.
Oxidative stress is one of the most important physiological stressors observed in aquaculture, particularly in species such as abalone (Haliotis spp), whose metabolic properties and environmental stressors render them vulnerable to reactive oxygen species (ROS). ... …
Oxidative stress is one of the most important physiological stressors observed in aquaculture, particularly in species such as …
Astaxanthin, oxidative stress, inflammation and cardiovascular disease.
Fassett RG, Coombes JS. Fassett RG, et al. Future Cardiol. 2009 Jul;5(4):333-42. doi: 10.2217/fca.09.19. Future Cardiol. 2009. PMID: 19656058 Review.
There have been at least eight clinical studies conducted in over 180 humans using astaxanthin to assess its safety, bioavailability and clinical aspects relevant to oxidative stress, inflammation or the cardiovascular system. ...Studies have demonstrated red …
There have been at least eight clinical studies conducted in over 180 humans using astaxanthin to assess its safety, bioavailability …
Astaxanthin ameliorates benzalkonium chloride-induced dry eye disease through suppressing inflammation and oxidative stress via Keap1-Nrf2/HO-1 signaling pathways.
Liu Z, Li Y, Bao J, Li S, Wen Y, Zhang P, Feng J, Wang Y, Tian L, Jie Y. Liu Z, et al. Animal Model Exp Med. 2025 Jun;8(6):1056-1079. doi: 10.1002/ame2.70000. Epub 2025 Mar 5. Animal Model Exp Med. 2025. PMID: 40045550 Free PMC article.
RESULTS: Network pharmacology suggests that AST may alleviate DED by influencing oxidation-reduction signaling pathways and reducing oxidative stress provoked by BAC. In vivo experiments demonstrated an improved overall condition in AST-administered mice in contrast …
RESULTS: Network pharmacology suggests that AST may alleviate DED by influencing oxidation-reduction signaling pathways and reducing oxid …
Oxidative stress induced by plasma-activated water stimulates astaxanthin production in Phaffia rhodozyma.
Li W, Luna-Flores CH, Anangi R, Zhou R, Tan X, Jessen M, Liu L, Zhou R, Zhang T, Gissibl A, Cullen PJ, Ostrikov KK, Speight RE. Li W, et al. Bioresour Technol. 2023 Feb;369:128370. doi: 10.1016/j.biortech.2022.128370. Epub 2022 Nov 21. Bioresour Technol. 2023. PMID: 36423765
In this study, a bubble discharge reactor was developed to generate plasma-activated water (PAW) to produce PAW-made yeast malt (YM) medium. Due to oxidative stress induced by PAW, strains cultured in 15 and 30 min-treated PAW-made medium produced 7.9 1.2 % and 12 …
In this study, a bubble discharge reactor was developed to generate plasma-activated water (PAW) to produce PAW-made yeast malt (YM) medium. …
Effects of Astaxanthin Supplementation on Oxidative Stress.
Wu D, Xu H, Chen J, Zhang L. Wu D, et al. Int J Vitam Nutr Res. 2020 Jan;90(1-2):179-194. doi: 10.1024/0300-9831/a000497. Epub 2019 Apr 15. Int J Vitam Nutr Res. 2020. PMID: 30982442 Free article. Clinical Trial.

For dosage subgroup analysis, high dose ( 20 mg/day) of astaxanthin showed significant antioxidant effect (on total antioxidant capacity, isoprostane, and superoxide dismutase, p < 0.05). ...This review suggested that the antioxidant effect of astaxanthin on huma

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For dosage subgroup analysis, high dose ( 20 mg/day) of astaxanthin showed significant antioxidant effect (on total antioxidant capac …
Astaxanthin inhibiting oxidative stress damage of placental trophoblast cells in vitro.
Fu JY, Jing Y, Xiao YP, Wang XH, Guo YW, Zhu YJ. Fu JY, et al. Syst Biol Reprod Med. 2021 Feb;67(1):79-88. doi: 10.1080/19396368.2020.1824031. Epub 2020 Oct 25. Syst Biol Reprod Med. 2021. PMID: 33103484
Oxidative stress from the trophoblasts is one of the possible pathological mechanisms of Preeclampsia (PE). This study aimed at exploring the potential effects of astaxanthin (ATX) on oxidative stress damaged placental trophoblast cell line HTR- …
Oxidative stress from the trophoblasts is one of the possible pathological mechanisms of Preeclampsia (PE). This study aimed a …
1,025 results