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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1982 1
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1984 3
1985 6
1986 9
1987 3
1988 4
1989 5
1990 10
1991 6
1992 7
1993 6
1994 5
1995 5
1996 9
1997 5
1998 2
1999 2
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2005 1
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2018 1
2023 1
2025 0

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97 results

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Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Second-generation antihistamines: a comparative review.
Slater JW, Zechnich AD, Haxby DG. Slater JW, et al. Drugs. 1999 Jan;57(1):31-47. doi: 10.2165/00003495-199957010-00004. Drugs. 1999. PMID: 9951950
This article evaluates second-generation antihistamines, including acrivastine, astemizole, azelastine, cetirizine, ebastine, fexofenadine, ketotifen, loratadine, mizolastine and terfenadine, for significant features that affect choice. ...Conditions that result in accumul …
This article evaluates second-generation antihistamines, including acrivastine, astemizole, azelastine, cetirizine, ebastine, fexofen …
Astemizole in the treatment of hay fever.
Malmberg H, Holopainen E, Grahne B, Binder E, Savolainen S, Sundberg S. Malmberg H, et al. Allergy. 1983 May;38(4):227-31. doi: 10.1111/j.1398-9995.1983.tb01615.x. Allergy. 1983. PMID: 6408940 Clinical Trial.
A double-blind parallel trial of astemizole, pheniramine and placebo was carried out in 51 patients with hay fever. Astemizole is a new potent H1-antihistamine with long duration of action but devoid of central activity. ...Tiredness and anticholinergic side effects …
A double-blind parallel trial of astemizole, pheniramine and placebo was carried out in 51 patients with hay fever. Astemizole …
Astemizole in combination with pseudoephedrine in the treatment of seasonal allergic rhinitis.
Simola M, Böss I, Holopainen E, Malmberg H, Ruoppi P, Seppä J, Siivonen L, Suonpää J, Piepponen T. Simola M, et al. Rhinology. 1996 Mar;34(1):21-3. Rhinology. 1996. PMID: 8739863 Clinical Trial.
The efficacy and side effects of once-daily astemizole-D, a combination of 10 mg astemizole and 240 mg pseudoephedrine, were compared with those of twice-daily brompheniramine-D, a combination of 12 mg brompheniramine and 50 mg phenylpropanolamine (Lunerin), in 64 p …
The efficacy and side effects of once-daily astemizole-D, a combination of 10 mg astemizole and 240 mg pseudoephedrine, were c …
[Efficacy and safety of astemizole in the treatment of allergic rhinitis and urticaria: a systematic review with meta-analysis].
Gutiérrez Castrellón P, Ramírez Mayans J, López Pérez G. Gutiérrez Castrellón P, et al. Rev Alerg Mex. 2005 May-Jun;52(3):113-26. Rev Alerg Mex. 2005. PMID: 16158785 Spanish.
OBJECTIVE: To compare astemizole with other first or second generation antihistaminics in the treatment of allergic rhinitis or urticaria. ...Finally, the safety area was analyzed considering the existence of sedation and headache; it was demonstrated less sedation (OR 0.2 …
OBJECTIVE: To compare astemizole with other first or second generation antihistaminics in the treatment of allergic rhinitis or urtic …
Astemizole--a new, non-sedating antihistamine for hayfever.
Knight A. Knight A. J Otolaryngol. 1985 Apr;14(2):85-8. J Otolaryngol. 1985. PMID: 2866257 Clinical Trial.
Astemizole significantly reduced the frequency and severity of allergic symptoms. In subjective evaluations of each treatment by both the investigator and the patients, astemizole was judged good to excellent by 68% compared to 30% for placebo (p less than 0.05). On …
Astemizole significantly reduced the frequency and severity of allergic symptoms. In subjective evaluations of each treatment by both …
Astemizole in perennial allergic rhinitis with seasonal exacerbations: a placebo-controlled double-blind study.
Tanay A, Neuman I. Tanay A, et al. Ann Allergy. 1989 Dec;63(6 Pt 1):493-4. Ann Allergy. 1989. PMID: 2574549 Clinical Trial.
Astemizole is a nonsedative H1-antagonist. It was used in a randomized double-blind, placebo-controlled in-season trial to assess its efficacy in patients with perennial allergic rhinitis showing seasonal exacerbations. ...Side effects were not appreciable throughout this …
Astemizole is a nonsedative H1-antagonist. It was used in a randomized double-blind, placebo-controlled in-season trial to assess its …
Pharmacological interventions for antipsychotic-related sialorrhea: a systematic review and network meta-analysis of randomized trials.
Fornaro M, Caiazza C, Solini N, De Prisco M, Billeci M, Vannini M, Shorr R, Caiolo S, Lussignoli M, Siskind D, Pigato G, Barone A, Sambataro F, de Bartolomeis A, Correll CU, Solmi M. Fornaro M, et al. Mol Psychiatry. 2023 Sep;28(9):3648-3660. doi: 10.1038/s41380-023-02266-x. Epub 2023 Oct 11. Mol Psychiatry. 2023. PMID: 37821573
. = 1.34-3.26), atropine, (RR = 2.03, 95% C.I. = 1.22-3.38), and astemizole, (RR = 1.70, 95% C.I. = 1.28-2.26) outperformed placebo, but not glycopyrrolate or ipratropium. Across secondary nodes (k = 28, n = 1821), antimuscarinics (RR = 2.26, 95% C.I. = 1.91-2.68), benzami …
. = 1.34-3.26), atropine, (RR = 2.03, 95% C.I. = 1.22-3.38), and astemizole, (RR = 1.70, 95% C.I. = 1.28-2.26) outperformed placebo, …
The effect of activated charcoal on the absorption and elimination of astemizole.
Laine K, Kivistö KT, Neuvonen PJ. Laine K, et al. Hum Exp Toxicol. 1994 Jul;13(7):502-5. doi: 10.1177/096032719401300709. Hum Exp Toxicol. 1994. PMID: 7917508 Clinical Trial.

Activated charcoal, administered immediately after astemizole ingestion, reduced the absorption of astemizole by 85% (P < 0.001). Multiple doses of activated charcoal, administered throughout the period of astemizole elimination, had no significant effect

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Activated charcoal, administered immediately after astemizole ingestion, reduced the absorption of astemizole by 85% (P < 0

…
A study of the interaction between dirithromycin and astemizole in healthy adults.
Bachmann K, Sullivan TJ, Reese JH, Jauregui L, Miller K, Scott M, Stotka J, Harris J. Bachmann K, et al. Am J Ther. 1997 Feb-Mar;4(2-3):73-9. doi: 10.1097/00045391-199702000-00004. Am J Ther. 1997. PMID: 10423595 Clinical Trial.
On the morning of the fourth dose of either dirithromycin or placebo each subject ingested a single 30-mg oral dose (three 10-mg tablets) of astemizole. The disposition kinetics of both astemizole and its major metabolite, N-desmethylastemizole, were characterized a …
On the morning of the fourth dose of either dirithromycin or placebo each subject ingested a single 30-mg oral dose (three 10-mg tablets) of …
Tilarin in combination with astemizole.
Bukstein DA, Biondi RM, Blumenthal MM, Dockhorn RJ, Filley WV, Fink J, Goldstein S, Graft DF, Hirsch SR, Joos TH, Melamed J, Rowe MS, Townley RG. Bukstein DA, et al. Allergy. 1996;51(28 Suppl):20-7. doi: 10.1111/j.1398-9995.1996.tb04775.x. Allergy. 1996. PMID: 8651473 Clinical Trial.
The specific question was, "Will the addition of nedocromil sodium 1% nasal spray to astemizole tablets improve control of symptoms of seasonal allergic rhinitis induced by ragweed pollen, as compared to astemizole therapy alone?'. ...Direct comparison of the active …
The specific question was, "Will the addition of nedocromil sodium 1% nasal spray to astemizole tablets improve control of symptoms o …
97 results