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Protective Effect of Ganoderma (Lingzhi) on Cardiovascular System.
Meng J, Yang B. Meng J, et al. Adv Exp Med Biol. 2019;1182:181-199. doi: 10.1007/978-981-32-9421-9_7. Adv Exp Med Biol. 2019. PMID: 31777019 Review.
CVDs are one of the most major causes of morbidity and mortality around the world, taking the lives of 17.9 million people every year. Several investigations have shown the influence of Ganoderma lucidum (G. lucidum, Lingzhi) on some metabolic markers, such a …
CVDs are one of the most major causes of morbidity and mortality around the world, taking the lives of 17.9 million people every year. Sever …
A network pharmacology analysis on drug-like compounds from Ganoderma lucidum for alleviation of atherosclerosis.
Oh KK, Adnan M, Cho DH. Oh KK, et al. J Food Biochem. 2021 Sep;45(9):e13906. doi: 10.1111/jfbc.13906. Epub 2021 Aug 18. J Food Biochem. 2021. PMID: 34409623
Ganoderma lucidum (GL) is known as a potent alleviator against chronic inflammatory disease like atherosclerosis (AS), but its mechanisms against AS have not been unveiled. ...Overall, we found that the identified 3 DLCs from GL have potent anti-inflammatory
Ganoderma lucidum (GL) is known as a potent alleviator against chronic inflammatory disease like atherosclerosis (AS),
Ganoderma lucidum spore ethanol extract attenuates atherosclerosis by regulating lipid metabolism via upregulation of liver X receptor alpha.
Lai P, Cao X, Xu Q, Liu Y, Li R, Zhang J, Zhang M. Lai P, et al. Pharm Biol. 2020 Dec;58(1):760-770. doi: 10.1080/13880209.2020.1798471. Pharm Biol. 2020. PMID: 32780606 Free PMC article.
CONTEXT: Ganoderma lucidum (Leyss.ex Fr.) Karst (Ganodermataceae) is a fungus that has been used in traditional Chinese medicine. OBJECTIVE: This is the first investigation of the lipid-lowering and anti-atherosclerotic effects of Ganoderma lucidum spo …
CONTEXT: Ganoderma lucidum (Leyss.ex Fr.) Karst (Ganodermataceae) is a fungus that has been used in traditional Chinese medici …
Herbal Medicine for Cardiovascular Diseases: Efficacy, Mechanisms, and Safety.
Shaito A, Thuan DTB, Phu HT, Nguyen THD, Hasan H, Halabi S, Abdelhady S, Nasrallah GK, Eid AH, Pintus G. Shaito A, et al. Front Pharmacol. 2020 Apr 7;11:422. doi: 10.3389/fphar.2020.00422. eCollection 2020. Front Pharmacol. 2020. PMID: 32317975 Free PMC article. Review.
Further, data on the ethnopharmacological therapeutic potentials and medicinal properties against CVDs of four widely used plants, namely Ginseng, Ginkgo biloba, Ganoderma lucidum, and Gynostemma pentaphyllum, are gathered and reviewed. ...
Further, data on the ethnopharmacological therapeutic potentials and medicinal properties against CVDs of four widely used plants, namely Gi …
Dingxin Recipe IV attenuates atherosclerosis by regulating lipid metabolism through LXR-α/SREBP1 pathway and modulating the gut microbiota in ApoE-/- mice fed with HFD.
Zhang Y, Gu Y, Chen Y, Huang Z, Li M, Jiang W, Chen J, Rao W, Luo S, Chen Y, Chen J, Li L, Jia Y, Liu M, Zhou F. Zhang Y, et al. J Ethnopharmacol. 2021 Feb 10;266:113436. doi: 10.1016/j.jep.2020.113436. Epub 2020 Oct 1. J Ethnopharmacol. 2021. PMID: 33011372 Free article.
Dingxin Recipe IV (DXR IV) was further improved from the DXR according to the traditional use. However, the mechanism of DXR IV in atherosclerosis is unclear. AIM OF THE STUDY: This study aimed to illustrate whether DXR IV improve atherosclerosis through modulating …
Dingxin Recipe IV (DXR IV) was further improved from the DXR according to the traditional use. However, the mechanism of DXR IV in athero
Ganoderma lucidum triterpenoids and polysaccharides attenuate atherosclerotic plaque in high-fat diet rabbits.
Li Y, Tang J, Gao H, Xu Y, Han Y, Shang H, Lu Y, Qin C. Li Y, et al. Nutr Metab Cardiovasc Dis. 2021 Jun 7;31(6):1929-1938. doi: 10.1016/j.numecd.2021.03.023. Epub 2021 Apr 6. Nutr Metab Cardiovasc Dis. 2021. PMID: 33992512
BACKGROUND AND AIMS: Atherosclerosis is characterized by lipid deposition, oxidative stress, and inflammation in the arterial intima. Ganoderma lucidum triterpenoids (GLTs) and polysaccharides (GLPs) are traditional Chinese medicines with potential cardiovasc …
BACKGROUND AND AIMS: Atherosclerosis is characterized by lipid deposition, oxidative stress, and inflammation in the arterial intima. …
Decreasing angiogenesis vasa vasorum through Lp-PLA2 and H2O2 inhibition by PSP from Ganoderma lucidum in atherosclerosis: in vivo diabetes mellitus type 2.
Wihastuti TA, Amiruddin R, Cesa FY, Alkaf AI, Setiawan M, Heriansyah T. Wihastuti TA, et al. J Basic Clin Physiol Pharmacol. 2020 Feb 7;30(6):/j/jbcpp.2019.30.issue-6/jbcpp-2019-0349/jbcpp-2019-0349.xml. doi: 10.1515/jbcpp-2019-0349. J Basic Clin Physiol Pharmacol. 2020. PMID: 32031980
Background Type 2 diabetes mellitus (T2DM) is a major risk factor of atherosclerosis. Hyperglycemia in T2DM causes advanced formation of glycation end products (AGE) which leads to oxidative stress and chronic inflammation. ...This result indicates that PSP prevents inflam …
Background Type 2 diabetes mellitus (T2DM) is a major risk factor of atherosclerosis. Hyperglycemia in T2DM causes advanced formation …
The role of polysaccharide peptide of Ganoderma lucidum as a potent antioxidant against atherosclerosis in high risk and stable angina patients.
Sargowo D, Ovianti N, Susilowati E, Ubaidillah N, Widya Nugraha A, Vitriyaturrida, Siwi Proboretno K, Failasufi M, Ramadhan F, Wulandari H, Waranugraha Y, Hayuning Putri D. Sargowo D, et al. Indian Heart J. 2018 Sep-Oct;70(5):608-614. doi: 10.1016/j.ihj.2017.12.007. Epub 2017 Dec 14. Indian Heart J. 2018. PMID: 30392496 Free PMC article. Clinical Trial.
Previous studies have proven the PsP of Ganoderma lucidum as an effective antioxidant in atherosclerotic rats and shows no toxicity in animal model. ...EPC count significantly reduced in high risk and stable angina with p=0.000. CONCLUSION: PsP of Ganoderma
Previous studies have proven the PsP of Ganoderma lucidum as an effective antioxidant in atherosclerotic rats and shows no tox …
The inhibitory effects of polysaccharide peptides (PsP) of Ganoderma lucidum against atherosclerosis in rats with dyslipidemia.
Wihastuti TA, Heriansyah T. Wihastuti TA, et al. Heart Int. 2017 Apr 12;12(1):e1-e7. doi: 10.5301/heartint.5000234. eCollection 2017 Jan-Dec. Heart Int. 2017. PMID: 29114382 Free PMC article.
BACKGROUND: Atherosclerosis occurs as a result of low-density lipoprotein (LDL) deposits oxidation. ...Further studies are required to determine the antioxidant effects of PsP G. lucidum and its benefits in the management of dyslipidemia....
BACKGROUND: Atherosclerosis occurs as a result of low-density lipoprotein (LDL) deposits oxidation. ...Further studies are required t …
Ganoderma lucidum inhibits inducible nitric oxide synthase expression in macrophages.
Woo CW, Man RY, Siow YL, Choy PC, Wan EW, Lau CS, O K. Woo CW, et al. Mol Cell Biochem. 2005 Jul;275(1-2):165-71. doi: 10.1007/s11010-005-1352-9. Mol Cell Biochem. 2005. PMID: 16335796
The iNOS-mediated NO production plays a role in the development of atherosclerosis. Ganoderma lucidum (G. lucidum, Linzhi or Reishi) is a traditional herbal medicine which is commonly used as health supplement. ...These results suggest that G. …
The iNOS-mediated NO production plays a role in the development of atherosclerosis. Ganoderma lucidum (G. lucidum
22 results