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The role of polysaccharide peptide of Ganoderma lucidum as a potent antioxidant against atherosclerosis in high risk and stable angina patients.
Sargowo D, Ovianti N, Susilowati E, Ubaidillah N, Widya Nugraha A, Vitriyaturrida, Siwi Proboretno K, Failasufi M, Ramadhan F, Wulandari H, Waranugraha Y, Hayuning Putri D. Sargowo D, et al. Indian Heart J. 2018 Sep-Oct;70(5):608-614. doi: 10.1016/j.ihj.2017.12.007. Epub 2017 Dec 14. Indian Heart J. 2018. PMID: 30392496 Free PMC article. Clinical Trial.
Previous studies have proven the PsP of Ganoderma lucidum as an effective antioxidant in atherosclerotic rats and shows no toxicity in animal model. ...EPC count significantly reduced in high risk and stable angina with p=0.000. CONCLUSION: PsP of Ganoderma
Previous studies have proven the PsP of Ganoderma lucidum as an effective antioxidant in atherosclerotic rats and shows no tox …
Protective Effect of Ganoderma (Lingzhi) on Cardiovascular System.
Meng J, Yang B. Meng J, et al. Adv Exp Med Biol. 2019;1182:181-199. doi: 10.1007/978-981-32-9421-9_7. Adv Exp Med Biol. 2019. PMID: 31777019 Review.
CVDs are one of the most major causes of morbidity and mortality around the world, taking the lives of 17.9 million people every year. Several investigations have shown the influence of Ganoderma lucidum (G. lucidum, Lingzhi) on some metabolic markers, such a …
CVDs are one of the most major causes of morbidity and mortality around the world, taking the lives of 17.9 million people every year. Sever …
Ganoderma lucidum spore ethanol extract attenuates atherosclerosis by regulating lipid metabolism via upregulation of liver X receptor alpha.
Lai P, Cao X, Xu Q, Liu Y, Li R, Zhang J, Zhang M. Lai P, et al. Pharm Biol. 2020 Dec;58(1):760-770. doi: 10.1080/13880209.2020.1798471. Pharm Biol. 2020. PMID: 32780606 Free PMC article.
CONTEXT: Ganoderma lucidum (Leyss.ex Fr.) Karst (Ganodermataceae) is a fungus that has been used in traditional Chinese medicine. OBJECTIVE: This is the first investigation of the lipid-lowering and anti-atherosclerotic effects of Ganoderma lucidum spo …
CONTEXT: Ganoderma lucidum (Leyss.ex Fr.) Karst (Ganodermataceae) is a fungus that has been used in traditional Chinese medici …
Herbal Medicine for Cardiovascular Diseases: Efficacy, Mechanisms, and Safety.
Shaito A, Thuan DTB, Phu HT, Nguyen THD, Hasan H, Halabi S, Abdelhady S, Nasrallah GK, Eid AH, Pintus G. Shaito A, et al. Front Pharmacol. 2020 Apr 7;11:422. doi: 10.3389/fphar.2020.00422. eCollection 2020. Front Pharmacol. 2020. PMID: 32317975 Free PMC article. Review.
Further, data on the ethnopharmacological therapeutic potentials and medicinal properties against CVDs of four widely used plants, namely Ginseng, Ginkgo biloba, Ganoderma lucidum, and Gynostemma pentaphyllum, are gathered and reviewed. ...
Further, data on the ethnopharmacological therapeutic potentials and medicinal properties against CVDs of four widely used plants, namely Gi …
Decreasing angiogenesis vasa vasorum through Lp-PLA2 and H2O2 inhibition by PSP from Ganoderma lucidum in atherosclerosis: in vivo diabetes mellitus type 2.
Wihastuti TA, Amiruddin R, Cesa FY, Alkaf AI, Setiawan M, Heriansyah T. Wihastuti TA, et al. J Basic Clin Physiol Pharmacol. 2020 Feb 7;30(6):/j/jbcpp.2019.30.issue-6/jbcpp-2019-0349/jbcpp-2019-0349.xml. doi: 10.1515/jbcpp-2019-0349. J Basic Clin Physiol Pharmacol. 2020. PMID: 32031980
Background Type 2 diabetes mellitus (T2DM) is a major risk factor of atherosclerosis. Hyperglycemia in T2DM causes advanced formation of glycation end products (AGE) which leads to oxidative stress and chronic inflammation. ...This result indicates that PSP prevents inflam …
Background Type 2 diabetes mellitus (T2DM) is a major risk factor of atherosclerosis. Hyperglycemia in T2DM causes advanced formation …
Triterpenes and Aromatic Meroterpenoids with Antioxidant Activity and Neuroprotective Effects from Ganoderma lucidum.
Wang C, Liu X, Lian C, Ke J, Liu J. Wang C, et al. Molecules. 2019 Nov 28;24(23):4353. doi: 10.3390/molecules24234353. Molecules. 2019. PMID: 31795252 Free PMC article.
Reactive oxygen/nitrogen species generated in the human body can cause oxidative damage associated with many degenerative diseases such as atherosclerosis, dementia, coronary heart diseases, aging, and cancer. There is a great interest in developing new antioxidants from …
Reactive oxygen/nitrogen species generated in the human body can cause oxidative damage associated with many degenerative diseases such as …
The inhibitory effects of polysaccharide peptides (PsP) of Ganoderma lucidum against atherosclerosis in rats with dyslipidemia.
Wihastuti TA, Heriansyah T. Wihastuti TA, et al. Heart Int. 2017 Apr 12;12(1):e1-e7. doi: 10.5301/heartint.5000234. eCollection 2017 Jan-Dec. Heart Int. 2017. PMID: 29114382 Free PMC article.
BACKGROUND: Atherosclerosis occurs as a result of low-density lipoprotein (LDL) deposits oxidation. ...Further studies are required to determine the antioxidant effects of PsP G. lucidum and its benefits in the management of dyslipidemia....
BACKGROUND: Atherosclerosis occurs as a result of low-density lipoprotein (LDL) deposits oxidation. ...Further studies are required t …
Characterization, hypolipidemic and antioxidant activities of degraded polysaccharides from Ganoderma lucidum.
Xu Y, Zhang X, Yan XH, Zhang JL, Wang LY, Xue H, Jiang GC, Ma XT, Liu XJ. Xu Y, et al. Int J Biol Macromol. 2019 Aug 15;135:706-716. doi: 10.1016/j.ijbiomac.2019.05.166. Epub 2019 May 23. Int J Biol Macromol. 2019. PMID: 31129213
The aim of this work is to characterize the primary structure and physicochemical properties of natural polysaccharides (GLP) and degraded polysaccharides (GLP(UD)) from Ganoderma lucidum, and evaluate their hypolipidemic and antioxidant activities. The results of p …
The aim of this work is to characterize the primary structure and physicochemical properties of natural polysaccharides (GLP) and degraded p …
Ganoderma lucidum inhibits inducible nitric oxide synthase expression in macrophages.
Woo CW, Man RY, Siow YL, Choy PC, Wan EW, Lau CS, O K. Woo CW, et al. Mol Cell Biochem. 2005 Jul;275(1-2):165-71. doi: 10.1007/s11010-005-1352-9. Mol Cell Biochem. 2005. PMID: 16335796
The iNOS-mediated NO production plays a role in the development of atherosclerosis. Ganoderma lucidum (G. lucidum, Linzhi or Reishi) is a traditional herbal medicine which is commonly used as health supplement. ...These results suggest that G. …
The iNOS-mediated NO production plays a role in the development of atherosclerosis. Ganoderma lucidum (G. lucidum
Probing Lingzhi or Reishi medicinal mushroom Ganoderma lucidum (higher Basidiomycetes): a bitter mushroom with amazing health benefits.
Batra P, Sharma AK, Khajuria R. Batra P, et al. Int J Med Mushrooms. 2013;15(2):127-43. doi: 10.1615/intjmedmushr.v15.i2.20. Int J Med Mushrooms. 2013. PMID: 23557365 Review.
Ganoderma lucidum (Lingzhi or Reishi) is known as a bitter mushroom with remarkable health benefits. ...In spite of the voluminous literature available, G. lucidum is used mostly as an immune enhancer and a health supplement, not therapeutically. ...
Ganoderma lucidum (Lingzhi or Reishi) is known as a bitter mushroom with remarkable health benefits. ...In spite of the
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