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Year Number of Results
2000 2
2001 1
2002 2
2004 2
2005 2
2006 9
2007 9
2008 3
2009 3
2010 6
2011 5
2012 6
2013 6
2014 6
2015 3
2016 4
2017 7
2018 3
2019 5
2020 3
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High-risk periodontal pathogens contribute to the pathogenesis of atherosclerosis.
Bale BF, Doneen AL, Vigerust DJ. Bale BF, et al. Postgrad Med J. 2017 Apr;93(1098):215-220. doi: 10.1136/postgradmedj-2016-134279. Epub 2016 Nov 29. Postgrad Med J. 2017. PMID: 27899684 Free PMC article. Review.
Atherosclerosis remains the largest cause of death and disability. Studies indicate that the adverse cardiovascular effects from PD are due to a few putative or high-risk bacteria: Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Tannerella forsythia
Atherosclerosis remains the largest cause of death and disability. Studies indicate that the adverse cardiovascular effects from PD a
Aggregatibacter actinomycetemcomitans induces Th17 cells in atherosclerotic lesions.
Jia R, Hashizume-Takizawa T, Du Y, Yamamoto M, Kurita-Ochiai T. Jia R, et al. Pathog Dis. 2015 Apr;73(3):ftu027. doi: 10.1093/femspd/ftu027. Epub 2015 Jan 28. Pathog Dis. 2015. PMID: 25743474
However, the role of Th17 cells and IL-17 in atherosclerosis remains poorly understood. We previously reported that Aggregatibacter actinomycetemcomitans (Aa) bacteremia accelerated atherosclerosis accompanied by inflammation in apolipoprotein E-deficient spo …
However, the role of Th17 cells and IL-17 in atherosclerosis remains poorly understood. We previously reported that Aggregatibacter …
Aggregatibacter actinomycetemcomitans accelerates atherosclerosis with an increase in atherogenic factors in spontaneously hyperlipidemic mice.
Zhang T, Kurita-Ochiai T, Hashizume T, Du Y, Oguchi S, Yamamoto M. Zhang T, et al. FEMS Immunol Med Microbiol. 2010 Jul 1;59(2):143-51. doi: 10.1111/j.1574-695X.2010.00674.x. Epub 2010 Mar 23. FEMS Immunol Med Microbiol. 2010. PMID: 20482627 Free article.
These results suggest that systemic infection with A. actinomycetemcomitans accelerates atherosclerosis in Apoe(shl) mice by exposing the whole microorganisms or their products, followed by initiating inflammation. Increases in proatherogenic factors may explain the …
These results suggest that systemic infection with A. actinomycetemcomitans accelerates atherosclerosis in Apoe(shl) mice by e …
Periopathogens in atherosclerotic plaques of patients with both cardiovascular disease and chronic periodontitis.
Atarbashi-Moghadam F, Havaei SR, Havaei SA, Hosseini NS, Behdadmehr G, Atarbashi-Moghadam S. Atarbashi-Moghadam F, et al. ARYA Atheroscler. 2018 Mar;14(2):53-57. doi: 10.22122/arya.v14i2.1504. ARYA Atheroscler. 2018. PMID: 30108636 Free PMC article.
BACKGROUND: Atherosclerosis and periodontitis are both chronic inflammatory diseases. Although a strong relationship between the two has already been established, the underlying mechanism is unknown. The present study was conducted aiming to detect the deoxyribonucleic aci …
BACKGROUND: Atherosclerosis and periodontitis are both chronic inflammatory diseases. Although a strong relationship between the two …
Immunologic burden links periodontitis to acute coronary syndrome.
Liljestrand JM, Paju S, Pietiäinen M, Buhlin K, Persson GR, Nieminen MS, Sinisalo J, Mäntylä P, Pussinen PJ. Liljestrand JM, et al. Atherosclerosis. 2018 Jan;268:177-184. doi: 10.1016/j.atherosclerosis.2017.12.007. Epub 2017 Dec 6. Atherosclerosis. 2018. PMID: 29232563 Clinical Trial.
Levels of subgingival Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Porphyromonas endodontalis, Prevotella intermedia, Tannerella forsythia, Campylobacter rectus, and Fusobacterium nucleatum were determined by checkerboard DNA-DNA hybridization. ...
Levels of subgingival Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Porphyromonas endodontalis, Prevotella interme …
Salivary IgA to MAA-LDL and Oral Pathogens Are Linked to Coronary Disease.
Akhi R, Wang C, Nissinen AE, Kankaanpää J, Bloigu R, Paju S, Mäntylä P, Buhlin K, Sinisalo J, Pussinen PJ, Hörkkö S. Akhi R, et al. J Dent Res. 2019 Mar;98(3):296-303. doi: 10.1177/0022034518818445. Epub 2019 Jan 22. J Dent Res. 2019. PMID: 30669938
Oxidized low-density lipoproteins (OxLDLs) have a crucial role in atherosclerosis progression through initiation of immunological response. ...Elevated salivary IgA antibody levels to MAA-LDL, Rgp44 (gingipain A hemagglutinin domain of P. gingivalis), and Aa-HSP60 (heat sh …
Oxidized low-density lipoproteins (OxLDLs) have a crucial role in atherosclerosis progression through initiation of immunological res …
Oral Bacterial Signatures in Cerebral Thrombi of Patients With Acute Ischemic Stroke Treated With Thrombectomy.
Patrakka O, Pienimäki JP, Tuomisto S, Ollikainen J, Lehtimäki T, Karhunen PJ, Martiskainen M. Patrakka O, et al. J Am Heart Assoc. 2019 Jun 4;8(11):e012330. doi: 10.1161/JAHA.119.012330. J Am Heart Assoc. 2019. PMID: 31117858 Free PMC article.
The presence of Streptococcus species, mainly the Streptococcus mitis group, belonging to viridans streptococci as well as Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans in samples were determined using a quantitative polymerase chain reaction with spec …
The presence of Streptococcus species, mainly the Streptococcus mitis group, belonging to viridans streptococci as well as Porphyromonas gin …
Mechanisms underlying the association between periodontitis and atherosclerotic disease.
Schenkein HA, Papapanou PN, Genco R, Sanz M. Schenkein HA, et al. Periodontol 2000. 2020 Jun;83(1):90-106. doi: 10.1111/prd.12304. Periodontol 2000. 2020. PMID: 32385879 Review.
Such organisms include the periodontal pathogens Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans, Prevotella intermedia, Tannerella forsythia, and Fusobacterium nucleatum. ...The second category of mechanisms potentially linking periodontitis to atherosc
Such organisms include the periodontal pathogens Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans, Prevotella intermed …
Biologically Defined or Biologically Informed Traits Are More Heritable Than Clinically Defined Ones: The Case of Oral and Dental Phenotypes.
Agler CS, Moss K, Philips KH, Marchesan JT, Simancas-Pallares M, Beck JD, Divaris K. Agler CS, et al. Adv Exp Med Biol. 2019;1197:179-189. doi: 10.1007/978-3-030-28524-1_13. Adv Exp Med Biol. 2019. PMID: 31732942 Free PMC article.
We used genome-wide association (GWAS) data combined with clinical and biomarker information in the Dental Atherosclerosis Risk In Communities (ARIC) cohort. ..."High gingival index" and "high red complex colonization" had h(2) > 0.50, while a periodontal complex trait …
We used genome-wide association (GWAS) data combined with clinical and biomarker information in the Dental Atherosclerosis Risk In Co …
Natural Monoclonal Antibody to Oxidized Low-Density Lipoprotein and Aggregatibacter actinomycetemcomitans.
Wang C, Hörkkö S. Wang C, et al. Methods Mol Biol. 2017;1643:155-167. doi: 10.1007/978-1-4939-7180-0_12. Methods Mol Biol. 2017. PMID: 28667536
The data showed that the Aa_Mab cross-reacted with Aggregatibacter actinomycetemcomitans (Aa) bacteria, an important oral pathogen in periodontitis associated with atherosclerosis. Surprisingly, the binding molecule of Aa bacteria to the Aa_Mab was Aa chaperonin 60 …
The data showed that the Aa_Mab cross-reacted with Aggregatibacter actinomycetemcomitans (Aa) bacteria, an important oral pathogen in …
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