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2000 2
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2004 2
2005 2
2006 9
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2008 3
2009 3
2010 6
2011 5
2012 6
2013 6
2014 6
2015 3
2016 4
2017 7
2018 3
2019 5
2020 3
2021 6
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Mechanisms underlying the association between periodontitis and atherosclerotic disease.
Schenkein HA, Papapanou PN, Genco R, Sanz M. Schenkein HA, et al. Periodontol 2000. 2020 Jun;83(1):90-106. doi: 10.1111/prd.12304. Periodontol 2000. 2020. PMID: 32385879 Review.
Such organisms include the periodontal pathogens Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans, Prevotella intermedia, Tannerella forsythia, and Fusobacterium nucleatum. ...The second category of mechanisms potentially linking periodontitis to atherosc …
Such organisms include the periodontal pathogens Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans, Prevotella intermed …
Aggregatibacter actinomycetemcomitans accelerates atherosclerosis with an increase in atherogenic factors in spontaneously hyperlipidemic mice.
Zhang T, Kurita-Ochiai T, Hashizume T, Du Y, Oguchi S, Yamamoto M. Zhang T, et al. FEMS Immunol Med Microbiol. 2010 Jul 1;59(2):143-51. doi: 10.1111/j.1574-695X.2010.00674.x. Epub 2010 Mar 23. FEMS Immunol Med Microbiol. 2010. PMID: 20482627 Free article.
We assessed the involvement of the periodontal pathogen Aggregatibacter actinomycetemcomitans and cariogenic pathogen Streptococcus mutans in the development of atherosclerosis in apolipoprotein E-deficient spontaneously hyperlipidemic (Apoe(shl)) mice. ...Increases …
We assessed the involvement of the periodontal pathogen Aggregatibacter actinomycetemcomitans and cariogenic pathogen Streptococcus m …
High-risk periodontal pathogens contribute to the pathogenesis of atherosclerosis.
Bale BF, Doneen AL, Vigerust DJ. Bale BF, et al. Postgrad Med J. 2017 Apr;93(1098):215-220. doi: 10.1136/postgradmedj-2016-134279. Epub 2016 Nov 29. Postgrad Med J. 2017. PMID: 27899684 Free PMC article. Review.
PD is a common chronic condition affecting the majority of Americans 30 years of age and older. Atherosclerosis remains the largest cause of death and disability. Studies indicate that the adverse cardiovascular effects from PD are due to a few putative or high-risk bacter …
PD is a common chronic condition affecting the majority of Americans 30 years of age and older. Atherosclerosis remains the largest c …
Periodontal pathogens and atherosclerosis: implications of inflammation and oxidative modification of LDL.
Kurita-Ochiai T, Yamamoto M. Kurita-Ochiai T, et al. Biomed Res Int. 2014;2014:595981. doi: 10.1155/2014/595981. Epub 2014 May 18. Biomed Res Int. 2014. PMID: 24949459 Free PMC article. Review.
In this review, we focus on the role of inflammatory mechanisms and oxidative modification in the formation and activation of atherosclerotic plaques accelerated by P. gingivalis or A. actinomycetemcomitans in an ApoE-deficient mouse model and high-fat-diet-fed mice. Furth …
In this review, we focus on the role of inflammatory mechanisms and oxidative modification in the formation and activation of atheroscleroti …
Aggregatibacter actinomycetemcomitans induces Th17 cells in atherosclerotic lesions.
Jia R, Hashizume-Takizawa T, Du Y, Yamamoto M, Kurita-Ochiai T. Jia R, et al. Pathog Dis. 2015 Apr;73(3):ftu027. doi: 10.1093/femspd/ftu027. Epub 2015 Jan 28. Pathog Dis. 2015. PMID: 25743474
Th17 cells have been linked to the pathogenesis of several chronic inflammatory and autoimmune diseases. However, the role of Th17 cells and IL-17 in atherosclerosis remains poorly understood. We previously reported that Aggregatibacter actinomycetemcomitans (Aa) ba …
Th17 cells have been linked to the pathogenesis of several chronic inflammatory and autoimmune diseases. However, the role of Th17 cells and …
Associations of Antibodies Targeting Periodontal Pathogens With Subclinical Coronary, Carotid, and Peripheral Arterial Atherosclerosis in Rheumatoid Arthritis.
Giles JT, Reinholdt J, Andrade F, Konig MF. Giles JT, et al. Arthritis Rheumatol. 2021 Apr;73(4):568-575. doi: 10.1002/art.41572. Epub 2021 Mar 3. Arthritis Rheumatol. 2021. PMID: 33205531 Free PMC article.
Anti-Aa and/or anti-LtxA seropositivity was significantly associated with all other assessed measures of atherosclerosis except carotid plaque. Anti-Pg was not associated with any measure of atherosclerosis. ...CONCLUSION: Immunoreactivity against Aa and/or its majo …
Anti-Aa and/or anti-LtxA seropositivity was significantly associated with all other assessed measures of atherosclerosis except carot …
Periodontal pathogen accelerates lipid peroxidation and atherosclerosis.
Jia R, Kurita-Ochiai T, Oguchi S, Yamamoto M. Jia R, et al. J Dent Res. 2013 Mar;92(3):247-52. doi: 10.1177/0022034513475625. Epub 2013 Jan 25. J Dent Res. 2013. PMID: 23355524
We previously reported that intravenous challenge with Aggregatibacter actinomycetemcomitans (Aa) accelerated atherosclerosis in apolipoprotein E-deficient spontaneously hyperlipidemic (Apoe(shl)) mice. In this study, we investigated whether live cells were required …
We previously reported that intravenous challenge with Aggregatibacter actinomycetemcomitans (Aa) accelerated atherosclerosis …
Humoral immune response to heat shock protein 60 of Aggregatibacter actinomycetemcomitans and cross-reactivity with malondialdehyde acetaldehyde-modified LDL.
Kyrklund M, Bildo M, Akhi R, Nissinen AE, Pussinen P, Hörkkö S, Wang C. Kyrklund M, et al. PLoS One. 2020 Mar 25;15(3):e0230682. doi: 10.1371/journal.pone.0230682. eCollection 2020. PLoS One. 2020. PMID: 32210456 Free PMC article.
Atherosclerosis is a chronic inflammatory disease and major cause of mortality worldwide. ...Through the oxidation, highly immunogenic epitopes are created and the immune system is activated. Association between atherosclerosis and periodontal diseases is well docum …
Atherosclerosis is a chronic inflammatory disease and major cause of mortality worldwide. ...Through the oxidation, highly immunogeni …
Natural Monoclonal Antibody to Oxidized Low-Density Lipoprotein and Aggregatibacter actinomycetemcomitans.
Wang C, Hörkkö S. Wang C, et al. Methods Mol Biol. 2017;1643:155-167. doi: 10.1007/978-1-4939-7180-0_12. Methods Mol Biol. 2017. PMID: 28667536
The data showed that the Aa_Mab cross-reacted with Aggregatibacter actinomycetemcomitans (Aa) bacteria, an important oral pathogen in periodontitis associated with atherosclerosis. Surprisingly, the binding molecule of Aa bacteria to the Aa_Mab was Aa chaperonin 60 …
The data showed that the Aa_Mab cross-reacted with Aggregatibacter actinomycetemcomitans (Aa) bacteria, an important oral pathogen in …
Distinct Microbial Signatures between Periodontal Profile Classes.
Marchesan JT, Moss K, Morelli T, Teles FR, Divaris K, Styner M, Ribeiro AA, Webster-Cyriaque J, Beck J. Marchesan JT, et al. J Dent Res. 2021 Nov;100(12):1405-1413. doi: 10.1177/00220345211009767. Epub 2021 Apr 27. J Dent Res. 2021. PMID: 33906500 Free article.
We used demographic, microbial (subgingival biofilm composition), and immunological data (serum IgG antibody levels, obtained with checkerboard immunoblotting technique) for 1,450 adult participants of the Dental Atherosclerosis Risk in Communities (ARIC) study, with alrea …
We used demographic, microbial (subgingival biofilm composition), and immunological data (serum IgG antibody levels, obtained with checkerbo …
84 results