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Page 1
Did you mean asthma a pai (152 results)?
Raver1 links Ripk1 RNA splicing to caspase-8-mediated pyroptotic cell death, inflammation, and pathogen resistance.
Zhang B, Orning P, Lehman JW, Dinis A, Torres-Ulloa L, Elling R, Kelliher MA, Bertin J, Proulx MK, Ryan L, Kandasamy R, Espevik T, Pai AA, Fitzgerald KA, Lien E. Zhang B, et al. Among authors: pai aa. bioRxiv [Preprint]. 2024 Nov 29:2024.11.27.625707. doi: 10.1101/2024.11.27.625707. bioRxiv. 2024. PMID: 39651143 Free PMC article. Preprint.
mRNA initiation and termination are spatially coordinated.
Calvo-Roitberg E, Carroll CL, Venev SV, Kim G, Mick ST, Dekker J, Fiszbein A, Pai AA. Calvo-Roitberg E, et al. Among authors: pai aa. bioRxiv [Preprint]. 2024 Jan 7:2024.01.05.574404. doi: 10.1101/2024.01.05.574404. bioRxiv. 2024. PMID: 38260419 Free PMC article. Preprint.
A cohesin traffic pattern genetically linked to gene regulation.
Valton AL, Venev SV, Mair B, Khokhar ES, Tong AHY, Usaj M, Chan K, Pai AA, Moffat J, Dekker J. Valton AL, et al. Among authors: pai aa. Nat Struct Mol Biol. 2022 Dec;29(12):1239-1251. doi: 10.1038/s41594-022-00890-9. Epub 2022 Dec 8. Nat Struct Mol Biol. 2022. PMID: 36482254 Free PMC article.
Self-inactivating, all-in-one AAV vectors for precision Cas9 genome editing via homology-directed repair in vivo.
Ibraheim R, Tai PWL, Mir A, Javeed N, Wang J, Rodríguez TC, Namkung S, Nelson S, Khokhar ES, Mintzer E, Maitland S, Chen Z, Cao Y, Tsagkaraki E, Wolfe SA, Wang D, Pai AA, Xue W, Gao G, Sontheimer EJ. Ibraheim R, et al. Among authors: pai aa. Nat Commun. 2021 Nov 1;12(1):6267. doi: 10.1038/s41467-021-26518-y. Nat Commun. 2021. PMID: 34725353 Free PMC article.
A divalent siRNA chemical scaffold for potent and sustained modulation of gene expression throughout the central nervous system.
Alterman JF, Godinho BMDC, Hassler MR, Ferguson CM, Echeverria D, Sapp E, Haraszti RA, Coles AH, Conroy F, Miller R, Roux L, Yan P, Knox EG, Turanov AA, King RM, Gernoux G, Mueller C, Gray-Edwards HL, Moser RP, Bishop NC, Jaber SM, Gounis MJ, Sena-Esteves M, Pai AA, DiFiglia M, Aronin N, Khvorova A. Alterman JF, et al. Among authors: pai aa. Nat Biotechnol. 2019 Aug;37(8):884-894. doi: 10.1038/s41587-019-0205-0. Epub 2019 Aug 2. Nat Biotechnol. 2019. PMID: 31375812 Free PMC article.
Nuclear Localization of Huntingtin mRNA Is Specific to Cells of Neuronal Origin.
Didiot MC, Ferguson CM, Ly S, Coles AH, Smith AO, Bicknell AA, Hall LM, Sapp E, Echeverria D, Pai AA, DiFiglia M, Moore MJ, Hayward LJ, Aronin N, Khvorova A. Didiot MC, et al. Among authors: pai aa. Cell Rep. 2018 Sep 4;24(10):2553-2560.e5. doi: 10.1016/j.celrep.2018.07.106. Cell Rep. 2018. PMID: 30184490 Free PMC article.
Widespread Shortening of 3' Untranslated Regions and Increased Exon Inclusion Are Evolutionarily Conserved Features of Innate Immune Responses to Infection.
Pai AA, Baharian G, Pagé Sabourin A, Brinkworth JF, Nédélec Y, Foley JW, Grenier JC, Siddle KJ, Dumaine A, Yotova V, Johnson ZP, Lanford RE, Burge CB, Barreiro LB. Pai AA, et al. PLoS Genet. 2016 Sep 30;12(9):e1006338. doi: 10.1371/journal.pgen.1006338. eCollection 2016 Sep. PLoS Genet. 2016. PMID: 27690314 Free PMC article.
Comparative studies of gene regulatory mechanisms.
Pai AA, Gilad Y. Pai AA, et al. Curr Opin Genet Dev. 2014 Dec;29:68-74. doi: 10.1016/j.gde.2014.08.010. Epub 2014 Sep 16. Curr Opin Genet Dev. 2014. PMID: 25215415 Free PMC article. Review.
Controls of nucleosome positioning in the human genome.
Gaffney DJ, McVicker G, Pai AA, Fondufe-Mittendorf YN, Lewellen N, Michelini K, Widom J, Gilad Y, Pritchard JK. Gaffney DJ, et al. Among authors: pai aa. PLoS Genet. 2012;8(11):e1003036. doi: 10.1371/journal.pgen.1003036. Epub 2012 Nov 15. PLoS Genet. 2012. PMID: 23166509 Free PMC article.
Regulatory element copy number differences shape primate expression profiles.
Iskow RC, Gokcumen O, Abyzov A, Malukiewicz J, Zhu Q, Sukumar AT, Pai AA, Mills RE, Habegger L, Cusanovich DA, Rubel MA, Perry GH, Gerstein M, Stone AC, Gilad Y, Lee C. Iskow RC, et al. Among authors: pai aa. Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):12656-61. doi: 10.1073/pnas.1205199109. Epub 2012 Jul 13. Proc Natl Acad Sci U S A. 2012. PMID: 22797897 Free PMC article.
DNase I sensitivity QTLs are a major determinant of human expression variation.
Degner JF, Pai AA, Pique-Regi R, Veyrieras JB, Gaffney DJ, Pickrell JK, De Leon S, Michelini K, Lewellen N, Crawford GE, Stephens M, Gilad Y, Pritchard JK. Degner JF, et al. Among authors: pai aa. Nature. 2012 Feb 5;482(7385):390-4. doi: 10.1038/nature10808. Nature. 2012. PMID: 22307276 Free PMC article.
Dissecting the regulatory architecture of gene expression QTLs.
Gaffney DJ, Veyrieras JB, Degner JF, Pique-Regi R, Pai AA, Crawford GE, Stephens M, Gilad Y, Pritchard JK. Gaffney DJ, et al. Among authors: pai aa. Genome Biol. 2012 Jan 31;13(1):R7. doi: 10.1186/gb-2012-13-1-r7. Genome Biol. 2012. PMID: 22293038 Free PMC article.
Noisy splicing drives mRNA isoform diversity in human cells.
Pickrell JK, Pai AA, Gilad Y, Pritchard JK. Pickrell JK, et al. Among authors: pai aa. PLoS Genet. 2010 Dec 9;6(12):e1001236. doi: 10.1371/journal.pgen.1001236. PLoS Genet. 2010. PMID: 21151575 Free PMC article.