Atosiban versus placebo for threatened preterm birth (APOSTEL 8): a multicentre, randomised controlled trial.
van der Windt LI, Klumper J, Duijnhoven RG, Kok M, Ris-Stalpers C, de Boer MA, van Kaam AH, Pajkrt E, Mol BW, Walker KF, McAuliffe FM, van der Post JA, Roos C, Oudijk MA; APOSTEL 8 Study Group.
van der Windt LI, et al.
Lancet. 2025 Mar 22;405(10483):1004-1013. doi: 10.1016/S0140-6736(25)00295-8. Epub 2025 Mar 3.
Lancet. 2025.
PMID: 40049187
Clinical Trial.
FINDINGS: Between Dec 4, 2017, and July 24, 2023, a total of 755 participants were randomly assigned, of whom 752 were included in the intention-to-treat analysis (atosiban n=375, placebo n=377). The primary outcome occurred in 37 (8%) of 449 infants in the atosiban …
FINDINGS: Between Dec 4, 2017, and July 24, 2023, a total of 755 participants were randomly assigned, of whom 752 were included in the inten …