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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1965 1
1967 1
1968 6
1969 4
1970 6
1971 4
1972 8
1973 7
1974 8
1975 5
1976 16
1977 17
1978 16
1979 24
1980 29
1981 24
1982 25
1983 40
1984 32
1985 27
1986 48
1987 37
1988 44
1989 37
1990 44
1991 43
1992 39
1993 35
1994 33
1995 41
1996 34
1997 35
1998 34
1999 33
2000 26
2001 28
2002 19
2003 26
2004 23
2005 22
2006 24
2007 26
2008 29
2009 27
2010 22
2011 23
2012 27
2013 29
2014 28
2015 25
2016 29
2017 31
2018 19
2019 20
2020 34
2021 36
2022 46
2023 42
2024 21

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1,446 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Effect of Low-Concentration Atropine Eyedrops vs Placebo on Myopia Incidence in Children: The LAMP2 Randomized Clinical Trial.
Yam JC, Zhang XJ, Zhang Y, Yip BHK, Tang F, Wong ES, Bui CHT, Kam KW, Ng MPH, Ko ST, Yip WWK, Young AL, Tham CC, Chen LJ, Pang CP. Yam JC, et al. JAMA. 2023 Feb 14;329(6):472-481. doi: 10.1001/jama.2022.24162. JAMA. 2023. PMID: 36786791 Free PMC article. Clinical Trial.
INTERVENTIONS: Participants were assigned at random to the 0.05% atropine (n = 160), 0.01% atropine (n = 159), and placebo (n = 155) groups and had eyedrops applied once nightly in both eyes over 2 years. ...Photophobia was the most common adverse event and was repo …
INTERVENTIONS: Participants were assigned at random to the 0.05% atropine (n = 160), 0.01% atropine (n = 159), and placebo (n …
Efficacy and Safety of 8 Atropine Concentrations for Myopia Control in Children: A Network Meta-Analysis.
Ha A, Kim SJ, Shim SR, Kim YK, Jung JH. Ha A, et al. Ophthalmology. 2022 Mar;129(3):322-333. doi: 10.1016/j.ophtha.2021.10.016. Epub 2021 Oct 22. Ophthalmology. 2022. PMID: 34688698 Free article. Review.
TOPIC: Comparative efficacy and safety of different concentrations of atropine for myopia control. CLINICAL RELEVANCE: Atropine is known to be an effective intervention to delay myopia progression. ...DISCUSSION: The ranking probability for efficacy was not proporti …
TOPIC: Comparative efficacy and safety of different concentrations of atropine for myopia control. CLINICAL RELEVANCE: Atropine
Efficacy and Adverse Effects of Atropine in Childhood Myopia: A Meta-analysis.
Gong Q, Janowski M, Luo M, Wei H, Chen B, Yang G, Liu L. Gong Q, et al. JAMA Ophthalmol. 2017 Jun 1;135(6):624-630. doi: 10.1001/jamaophthalmol.2017.1091. JAMA Ophthalmol. 2017. PMID: 28494063 Free PMC article. Review.
IMPORTANCE: Some uncertainty about the clinical value and dosing of atropine for the treatment of myopia in children remains. OBJECTIVE: To evaluate the efficacy vs the adverse effects of various doses of atropine in the therapy for myopia in children. ...High-dose …
IMPORTANCE: Some uncertainty about the clinical value and dosing of atropine for the treatment of myopia in children remains. OBJECTI …
Atropine for the treatment of childhood myopia: safety and efficacy of 0.5%, 0.1%, and 0.01% doses (Atropine for the Treatment of Myopia 2).
Chia A, Chua WH, Cheung YB, Wong WL, Lingham A, Fong A, Tan D. Chia A, et al. Ophthalmology. 2012 Feb;119(2):347-54. doi: 10.1016/j.ophtha.2011.07.031. Epub 2011 Oct 2. Ophthalmology. 2012. PMID: 21963266 Clinical Trial.
PURPOSE: Our previous study, Atropine for the Treatment of Myopia 1 (ATOM1), showed that atropine 1% eyedrops were effective in controlling myopic progression but with visual side effects resulting from cycloplegia and mydriasis. ...Allergic conjunctivitis and derma …
PURPOSE: Our previous study, Atropine for the Treatment of Myopia 1 (ATOM1), showed that atropine 1% eyedrops were effective i …
Atropine for the treatment of childhood myopia.
Chua WH, Balakrishnan V, Chan YH, Tong L, Ling Y, Quah BL, Tan D. Chua WH, et al. Ophthalmology. 2006 Dec;113(12):2285-91. doi: 10.1016/j.ophtha.2006.05.062. Epub 2006 Sep 25. Ophthalmology. 2006. PMID: 16996612 Clinical Trial.
PURPOSE: To evaluate the efficacy and safety of topical atropine, a nonselective muscarinic antagonist, in slowing the progression of myopia and ocular axial elongation in Asian children. ...The differences in myopia progression and axial elongation between the 2 groups we …
PURPOSE: To evaluate the efficacy and safety of topical atropine, a nonselective muscarinic antagonist, in slowing the progression of …
Efficacy of atropine, orthokeratology, and combined atropine with orthokeratology for childhood myopia: A systematic review and network meta-analysis.
Tsai HR, Wang JH, Huang HK, Chen TL, Chen PW, Chiu CJ. Tsai HR, et al. J Formos Med Assoc. 2022 Dec;121(12):2490-2500. doi: 10.1016/j.jfma.2022.05.005. Epub 2022 Jun 7. J Formos Med Assoc. 2022. PMID: 35688780 Free article.
For refractive change, SUCRA analysis revealed that the hierarchy was high-dose (0.5%-1%), moderate-dose (0.1%-0.25%), and low-dose (0.01%-0.05%) atropine. Regarding AL, SUCRA analysis revealed the following hierarchy: Ortho-K combined with 0.01% atropine, high-dose …
For refractive change, SUCRA analysis revealed that the hierarchy was high-dose (0.5%-1%), moderate-dose (0.1%-0.25%), and low-dose (0.01%-0 …
Effect of atropine, orthokeratology and combined treatments for myopia control: a 2-year stratified randomised clinical trial.
Xu S, Li Z, Zhao W, Zheng B, Jiang J, Ye G, Feng Z, Long W, He L, He M, Hu Y, Yang X. Xu S, et al. Br J Ophthalmol. 2023 Nov 22;107(12):1812-1817. doi: 10.1136/bjo-2022-321272. Br J Ophthalmol. 2023. PMID: 36229177 Clinical Trial.
PURPOSE: To investigate the 2-year efficacy of atropine, orthokeratology (ortho-k) and combined treatment on myopia. ...Children (n=164) aged 8-12 years with spherical equivalent refraction of -1.00 to -6.00 D were stratified into two age subgroups and randomly assigned to …
PURPOSE: To investigate the 2-year efficacy of atropine, orthokeratology (ortho-k) and combined treatment on myopia. ...Children (n=1 …
Two-Year Clinical Trial of the Low-Concentration Atropine for Myopia Progression (LAMP) Study: Phase 2 Report.
Yam JC, Li FF, Zhang X, Tang SM, Yip BHK, Kam KW, Ko ST, Young AL, Tham CC, Chen LJ, Pang CP. Yam JC, et al. Ophthalmology. 2020 Jul;127(7):910-919. doi: 10.1016/j.ophtha.2019.12.011. Epub 2019 Dec 21. Ophthalmology. 2020. PMID: 32019700 Clinical Trial.
Compared with the first year, the second-year efficacy of 0.05% and 0.025% atropine remained similar (P >0.1), but improved mildly in the 0.01% atropine group (P = 0.04). ...Visual acuity and vision-related quality of life remained unaffected. CONCLUSIONS: Over 2 …
Compared with the first year, the second-year efficacy of 0.05% and 0.025% atropine remained similar (P >0.1), but improved mildly …
Atropine Treatment for Hypertrophic Pyloric Stenosis: A Systematic Review and Meta-Analysis.
Lauriti G, Cascini V, Chiesa PL, Pierro A, Zani A. Lauriti G, et al. Eur J Pediatr Surg. 2018 Oct;28(5):393-399. doi: 10.1055/s-0037-1604116. Epub 2017 Jul 12. Eur J Pediatr Surg. 2018. PMID: 28701002 Review.
Our aims were to review the efficacy of atropine in treating HPS and to compare atropine therapy versus pyloromyotomy. ...Currently, there is no evidence-based literature to support atropine treatment in these infants. To our knowledge, atropine should …
Our aims were to review the efficacy of atropine in treating HPS and to compare atropine therapy versus pyloromyotomy. ...Curr …
Efficacy Comparison of Repeated Low-Level Red Light and Low-Dose Atropine for Myopia Control: A Randomized Controlled Trial.
Chen Y, Xiong R, Chen X, Zhang J, Bulloch G, Lin X, Wu X, Li J. Chen Y, et al. Transl Vis Sci Technol. 2022 Oct 3;11(10):33. doi: 10.1167/tvst.11.10.33. Transl Vis Sci Technol. 2022. PMID: 36269184 Free PMC article. Clinical Trial.
Participants were randomly assigned to the RLRL group or low-dose atropine (LDA, 0.01% atropine eye drops) group and were followed up at 1, 3, 6, and 12 months. ...CONCLUSIONS: In this study, RLRL was more effective for controlling AL and myopia progression over 12 …
Participants were randomly assigned to the RLRL group or low-dose atropine (LDA, 0.01% atropine eye drops) group and were foll …
1,446 results