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Year Number of Results
1946 1
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1948 1
1949 1
1950 2
1951 5
1952 4
1953 3
1954 5
1955 1
1956 5
1957 10
1958 10
1959 4
1960 5
1961 13
1962 8
1963 20
1964 54
1965 34
1966 39
1967 42
1968 70
1969 70
1970 82
1971 110
1972 93
1973 94
1974 101
1975 139
1976 106
1977 131
1978 140
1979 143
1980 121
1981 113
1982 141
1983 148
1984 178
1985 179
1986 185
1987 213
1988 241
1989 241
1990 206
1991 233
1992 267
1993 332
1994 272
1995 232
1996 275
1997 287
1998 350
1999 355
2000 437
2001 579
2002 642
2003 658
2004 821
2005 937
2006 1218
2007 1459
2008 1680
2009 1829
2010 2170
2011 2490
2012 3006
2013 3523
2014 3932
2015 4394
2016 4673
2017 5006
2018 5344
2019 5793
2020 6563
2021 7859
2022 7881
2023 7565
2024 3798

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A Systematic Review and Meta-Analysis of Social Cognition Among People Living with HIV: Implications for Non-Social Cognition and Social Everyday Functioning.
Vance DE, Billings R, Lambert CC, Fazeli PL, Goodin BR, Kempf MC, Rubin LH, Turan B, Wise J, Hellemann G, Lee J. Vance DE, et al. Neuropsychol Rev. 2024 Jun 13. doi: 10.1007/s11065-024-09643-5. Online ahead of print. Neuropsychol Rev. 2024. PMID: 38869661 Review.
Deficits in social cognition have been well documented in those with severe mental illness including schizophrenia and depression, those along the autism spectrum, and those with other brain disorders where such deficits profoundly impact everyday life. ...
Deficits in social cognition have been well documented in those with severe mental illness including schizophrenia and depression, those alo …
Child with Closed Head Injury and Persistent Vomiting.
Khan A. Khan A. Clin Pract Cases Emerg Med. 2024 May;8(2):171-173. doi: 10.5811/cpcem.4814. Clin Pract Cases Emerg Med. 2024. PMID: 38869345
CASE PRESENTATION: We present the case of a six-year-old child with autism who presented with persistent vomiting in the setting of a closed head injury (CHI). ...
CASE PRESENTATION: We present the case of a six-year-old child with autism who presented with persistent vomiting in the setting of a …
Prevalence of autism in first-episode psychosis in two Hong Kong teaching hospitals.
Kwok TT, Chan MM, Mo FY, Hung SF, Leung PW, Lai KY, Shea CK. Kwok TT, et al. Autism. 2024 Jun 13:13623613241259062. doi: 10.1177/13623613241259062. Online ahead of print. Autism. 2024. PMID: 38869152
By comprehensively examining the clinical profiles of 103 children and adolescents (below 18 years old) with first-episode psychosis and conducting the Autism Diagnostic Interview-Revised (the 'gold standard' autism diagnostic tool) with their primary caregivers, we …
By comprehensively examining the clinical profiles of 103 children and adolescents (below 18 years old) with first-episode psychosis and con …
The role of circadian rhythms and sleep in the aetiology of autism spectrum disorder and attention-deficit/hyperactivity disorder: New evidence from bidirectional two-sample Mendelian randomization analysis.
Dai X, Williams GJ, Groeger JA, Jones G, Brookes K, Zhou W, Hua J, Du W. Dai X, et al. Autism. 2024 Jun 13:13623613241258546. doi: 10.1177/13623613241258546. Online ahead of print. Autism. 2024. PMID: 38869021
Research shows that people with autism spectrum disorder and attention-deficit/hyperactivity disorder often have sleep issues and problems with the body's natural daily rhythms, known as circadian rhythms. ...It found that the timing of one's most active hour …
Research shows that people with autism spectrum disorder and attention-deficit/hyperactivity disorder often have sleep …
The Role of Sertoli Cell Hormones in Male Preponderance Observed in Autism Spectrum Disorder.
Göksoy ŞÇ, Tanır Y, Soylu N, Baki AM, Vural P, Karayağmurlu A. Göksoy ŞÇ, et al. Noro Psikiyatr Ars. 2024 May 29;61(2):141-147. doi: 10.29399/npa.28378. eCollection 2024. Noro Psikiyatr Ars. 2024. PMID: 38868849 Free PMC article.
INTRODUCTION: There is a significant, but poorly understood, male preponderance in prevalence of autism spectrum disorder (ASD). The aim of this study was to examine the relationship between male preponderance in ASD and Inhibin B (InhB) and Anti-Mullerian hormone ( …
INTRODUCTION: There is a significant, but poorly understood, male preponderance in prevalence of autism spectrum disorder (ASD …
Copy number variations in autistic children.
Alhazmi S, Alharthi M, Alzahrani M, Alrofaidi A, Basingab F, Almuhammadi A, Alkhatabi H, Ashi A, Chaudhary A, Elaimi A. Alhazmi S, et al. Biomed Rep. 2024 Jun 3;21(1):107. doi: 10.3892/br.2024.1795. eCollection 2024 Jul. Biomed Rep. 2024. PMID: 38868529 Free PMC article.
Autism spectrum disorder (ASD) manifests as a neurodevelopmental condition marked by challenges in social communication, interaction and the performing of repetitive behaviors. ...In the present study, CNVs in autistic Saudi Arabian children were identified t
Autism spectrum disorder (ASD) manifests as a neurodevelopmental condition marked by challenges in social communication, inter
Preliminary observations on the associations between sensory processing abnormalities and event-related potentials in adults with autism spectrum disorder.
Mizui R, Yamamuro K, Okazaki K, Uratani M, Kashida N, Ishida R, Makinodan M. Mizui R, et al. PCN Rep. 2024 Feb 14;3(1):e173. doi: 10.1002/pcn5.173. eCollection 2024 Mar. PCN Rep. 2024. PMID: 38868472 Free PMC article.
AIM: Autism spectrum disorder (ASD) is a neurodevelopmental disorder that is thought to involve a variety of neurophysiological characteristics. ...Correlations between each component and the scores of the Autism-Spectrum Quotient Japanese version (AQ- …
AIM: Autism spectrum disorder (ASD) is a neurodevelopmental disorder that is thought to involve a variety of neurophysi …
Association between marital satisfaction of female patients with persistent depressive disorder, and their own and husbands' autism spectrum disorder or attention deficit/hyperactivity disorder traits.
Toshishige Y, Kondo M, Watanabe T, Yamada A, Hashimoto H, Okazaki J, Tokuyama N, Kuwabara J, Mizushima H, Akechi T. Toshishige Y, et al. PCN Rep. 2023 May 16;2(2):e95. doi: 10.1002/pcn5.95. eCollection 2023 Jun. PCN Rep. 2023. PMID: 38868151 Free PMC article.
However, no studies have examined marital relationships in persistent depressive disorder (PDD) in terms of neurodevelopmental traits. This study aimed to explore the association between the autism spectrum disorder (ASD) or attention-deficit/hyperactivity …
However, no studies have examined marital relationships in persistent depressive disorder (PDD) in terms of neurodevelopmental traits …
Predictors of probable attention deficit hyperactivity disorder in elderly patients with mild cognitive impairment visiting a memory clinic.
Nagano S, Kamimura N, Sota S, Takahashi H, Suganuma N, Kazui H. Nagano S, et al. PCN Rep. 2023 May 25;2(2):e104. doi: 10.1002/pcn5.104. eCollection 2023 Jun. PCN Rep. 2023. PMID: 38868147 Free PMC article.
AIM: Characteristics of attention deficit hyperactivity disorder (ADHD) that persist into old age are often confused with symptoms of mild cognitive impairment (MCI), and the actual rate of probable ADHD in people with MCI is unknown. ...The MCI/ADHD (+) group mostly compr …
AIM: Characteristics of attention deficit hyperactivity disorder (ADHD) that persist into old age are often confused with symptoms of …
Prevalence of suspected autism spectrum disorder and attention-deficit hyperactivity disorder in a Japanese clinical sample with gambling disorder: A cross-sectional study.
So R, Sato Y, Hashimoto N, Furukawa TA. So R, et al. PCN Rep. 2023 Aug 13;2(3):e131. doi: 10.1002/pcn5.131. eCollection 2023 Sep. PCN Rep. 2023. PMID: 38867830 Free PMC article.
AIM: Studies show gambling disorders are associated with attention-deficit hyperactivity disorder (ADHD). The association between gambling disorders and autism spectrum disorder (ASD) has not been well studied, although ASD is often comorbid with ADHD and is …
AIM: Studies show gambling disorders are associated with attention-deficit hyperactivity disorder (ADHD). The association between gam …
[Neuroimaging-based study of scalp acupuncture targets for common psychiatric diseases (Part 2)].
Yu S, Cao J, Cui F, Zhang B, Liu J, Kong Q, Kong J. Yu S, et al. Zhongguo Zhen Jiu. 2024 Jun 12;44(6):703-14. doi: 10.13703/j.0255-2930.20230112-0003. Zhongguo Zhen Jiu. 2024. PMID: 38867635 Chinese.
In this study, based on the neuroimaging literature Meta analysis retrieved from Neurosynth platform, the scalp stimulation targets for common psychiatric diseases are developed, which provided the stimulation target protocols of scalp acupuncture for attention deficit hyperactiv …
In this study, based on the neuroimaging literature Meta analysis retrieved from Neurosynth platform, the scalp stimulation targets for comm …
Enhanced interest in letters and numbers in autistic children.
Ostrolenk A, Gagnon D, Boisvert M, Lemire O, Dick SC, Côté MP, Mottron L. Ostrolenk A, et al. Mol Autism. 2024 Jun 12;15(1):26. doi: 10.1186/s13229-024-00606-4. Mol Autism. 2024. PMID: 38867240
This study examines the magnitude and nature of the interest in written material in a large population of autistic and non-autistic children. METHODS: All 701 children (391 autistic, 310 non-autistic) under the age of 7 referred to an autism ass …
This study examines the magnitude and nature of the interest in written material in a large population of autistic and non-autisti
Assessing transcriptomic heterogeneity of single-cell RNASeq data by bulk-level gene expression data.
Tiong KL, Luzhbin D, Yeang CH. Tiong KL, et al. BMC Bioinformatics. 2024 Jun 12;25(1):209. doi: 10.1186/s12859-024-05825-3. BMC Bioinformatics. 2024. PMID: 38867193
In the true bulk-level mouse data, the sample mixture coefficients were unknown but the log-likelihood scores were strongly correlated with accuracy rates of inferred cell types. In the data of autism spectrum disorder (ASD) and normal controls, we found that ASD br …
In the true bulk-level mouse data, the sample mixture coefficients were unknown but the log-likelihood scores were strongly correlated with …
Combining developmental and sleep health measures for autism spectrum disorder screening: an ECHO study.
Shuffrey LC, Rennie B, Li X, Galai N, Pini N, Akbaryan A, Alshawabkeh A, Aschner J, Vargas JC, Costello L, D'Sa V, Deoni S, Dunlop A, Elliott AJ, Fifer WP, Hash J, Koinis-Mitchell D, Lai JS, Leventhal BL, Lewis J, Lucchini M, McArthur KL, Morales S, Nozadi SS, O'Connor TG, O'Shea TM, Page GP, Propper C, Sania A, Shuster C, Zimmerman E, Margolis AE; ECHO Cohort Consortium. Shuffrey LC, et al. Pediatr Res. 2024 Jun 12. doi: 10.1038/s41390-024-03306-0. Online ahead of print. Pediatr Res. 2024. PMID: 38867029
BACKGROUND: Sleep problems are reported for up to 80% of autistic individuals. We examined whether parsimonious sets of items derived from the Modified Checklist for Autism in Toddlers, Revised (M-CHAT-R) and the Brief Infant Sleep Questionnaire (BISQ) are superior …
BACKGROUND: Sleep problems are reported for up to 80% of autistic individuals. We examined whether parsimonious sets of items derived …
Association of preterm birth and birth size status with neurodevelopmental and psychiatric disorders in spontaneous births.
Kong L, Nivins S, Chen X, Liang Y, Gissler M, Lavebratt C. Kong L, et al. Eur Child Adolesc Psychiatry. 2024 Jun 12. doi: 10.1007/s00787-024-02489-5. Online ahead of print. Eur Child Adolesc Psychiatry. 2024. PMID: 38866929
We show that PTB across gestational ages, and SGA, were associated with higher risks for anxiety disorders, intellectual disabilities, specific developmental disorders (SDD), autism spectrum disorders (ASD), attention-deficit/hyperactivity disorders (ADHD) and other emotio …
We show that PTB across gestational ages, and SGA, were associated with higher risks for anxiety disorders, intellectual disabilities, speci …
Conditional knockout of Shank3 in the ventral CA1 by quantitative in vivo genome-editing impairs social memory in mice.
Chung M, Imanaka K, Huang Z, Watarai A, Wang MY, Tao K, Ejima H, Aida T, Feng G, Okuyama T. Chung M, et al. Nat Commun. 2024 Jun 12;15(1):4531. doi: 10.1038/s41467-024-48430-x. Nat Commun. 2024. PMID: 38866749
Individuals with autism spectrum disorder (ASD) have a higher prevalence of social memory impairment. ...
Individuals with autism spectrum disorder (ASD) have a higher prevalence of social memory impairment. ...
Pathways to epilepsy surgery in children with tuberous sclerosis complex-associated epilepsy.
Gauer L, Lagarde S, Valenti-Hirsch MP, Makhalova J, Milh M, Baer S, Lepine A, Ollivier I, Scavarda D, Hirsch E, Bartolomei F, De Saint-Martin A, Villeneuve N. Gauer L, et al. Rev Neurol (Paris). 2024 Jun 11:S0035-3787(24)00533-2. doi: 10.1016/j.neurol.2024.04.009. Online ahead of print. Rev Neurol (Paris). 2024. PMID: 38866657
The number of anti-seizure medications required decreased in 50% of cases after surgery. Infantile spasms, intellectual disability, autism spectrum disorder or severe behavioral disorders were not contraindications to surgery but were associated with a higher rate o …
The number of anti-seizure medications required decreased in 50% of cases after surgery. Infantile spasms, intellectual disability, autis
Engineered lignocellulosic based biochar to remove endocrine-disrupting chemicals: Assessment of binding mechanism.
Kumar V, Sharma P, Pasrija R, Chakraborty P, Basheer T, Thomas J, Sehgal SS, Gupta M, Muzammil K. Kumar V, et al. Chemosphere. 2024 Jun 10:142584. doi: 10.1016/j.chemosphere.2024.142584. Online ahead of print. Chemosphere. 2024. PMID: 38866332
These chemicals are associated with increasing occurrence of obesity, metabolic disorders, reproductive abnormalities, autism, cancer, epigenetic variation and cardiovascular risk. Conventional treatment processes are expensive, not environment friendly and unable to achie …
These chemicals are associated with increasing occurrence of obesity, metabolic disorders, reproductive abnormalities, autism, cancer …
Discovering the gene-brain-behavior link in autism via generative machine learning.
Kundu S, Sair H, Sherr EH, Mukherjee P, Rohde GK. Kundu S, et al. Sci Adv. 2024 Jun 14;10(24):eadl5307. doi: 10.1126/sciadv.adl5307. Epub 2024 Jun 12. Sci Adv. 2024. PMID: 38865470 Free article.
Autism is traditionally diagnosed behaviorally but has a strong genetic basis. A genetics-first approach could transform understanding and treatment of autism. However, isolating the gene-brain-behavior relationship from confounding sources of variability is a chall
Autism is traditionally diagnosed behaviorally but has a strong genetic basis. A genetics-first approach could transform understandin
Building Better Bridges: Outcomes of a Community-Partnered New School Transition Intervention for Students on the Autism Spectrum.
Nuske HJ, Smith T, Levato L, Bronstein B, Sparapani N, Garcia C, Castellon F, Lee HS, Vejnoska SF, Hochheimer S, Fitzgerald AR, Chiappe JC, Nunnally AD, Li J, Shih W, Brown A, Cullen M, Hund LM, Stahmer AC, Iadarola S, Mandell DS, Hassrick EM, Kataoka S, Kasari C. Nuske HJ, et al. J Autism Dev Disord. 2024 Jun 12. doi: 10.1007/s10803-024-06285-7. Online ahead of print. J Autism Dev Disord. 2024. PMID: 38865033
New school transitions can be challenging for students on the autism spectrum. No published, evidence-based interventions exist to support families and teachers of students transitioning to elementary and secondary school during this critical period. ...
New school transitions can be challenging for students on the autism spectrum. No published, evidence-based interventions exist to su …
Autistic adults in China and the Netherlands: Proxy-reported community integration and life satisfaction.
Liu F, Begeer S, Hoekstra RA, Wang C, Scheeren AM. Liu F, et al. Autism. 2024 Jun 12:13623613241258182. doi: 10.1177/13623613241258182. Online ahead of print. Autism. 2024. PMID: 38864577
Even though there are about 10 million Chinese autistic individuals, we know little about autistic adults in China. ...We included 99 autistic adults in China and 109 in the Netherlands (18-30 years). ...
Even though there are about 10 million Chinese autistic individuals, we know little about autistic adults in China. ...We incl …
Social challenges, autism spectrum disorder, and attention deficit/hyperactivity disorder in youth with neurofibromatosis type I.
Hocking MC, Albee MV, Kim M, Berman JI, Fisher MJ, Roberts TPL, Blaskey L. Hocking MC, et al. Appl Neuropsychol Child. 2024 Jun 12:1-9. doi: 10.1080/21622965.2024.2365383. Online ahead of print. Appl Neuropsychol Child. 2024. PMID: 38864448
OBJECTIVE: Youth with neurofibromatosis type I (NF1) demonstrate high rates of Autism Spectrum Disorder (ASD) and Attention Deficit/Hyperactivity Disorder (ADHD), which often have overlapping behaviors. ...RESULTS: ASD classification varied depending on the m …
OBJECTIVE: Youth with neurofibromatosis type I (NF1) demonstrate high rates of Autism Spectrum Disorder (ASD) and Attention De …
Academic learning challenges and links to vocational outcomes in young autistic adults.
Grosman HE, Aragon-Guevara D, McQuaid GA, Wallace GL, Lee NR. Grosman HE, et al. Autism. 2024 Jun 12:13623613241255774. doi: 10.1177/13623613241255774. Online ahead of print. Autism. 2024. PMID: 38864310
Finding a job can be hard for autistic adults. No studies have been completed that look into whether having difficulties learning and troubles finding a job are related in this population. ...These results suggest that the Learning Needs Screening Tool may help to identify …
Finding a job can be hard for autistic adults. No studies have been completed that look into whether having difficulties learning and …
Autistic adults' perspectives and experiences of diagnostic assessments that include play across the lifespan.
Pritchard-Rowe E, de Lemos C, Howard K, Gibson J. Pritchard-Rowe E, et al. Autism. 2024 Jun 12:13623613241257601. doi: 10.1177/13623613241257601. Online ahead of print. Autism. 2024. PMID: 38864307
Play is often included in autism diagnostic assessments. These assessments tend to focus on negatives and how people who are not autistic interpret observable behaviours. ...For example, some completed a diagnostic tool called the Autism Diagnostic Observatio …
Play is often included in autism diagnostic assessments. These assessments tend to focus on negatives and how people who are not a
Experiences of racism and racial disparities in health care among children and youth with autism and their caregivers: a systematic review.
Lindsay S, Li Y, Joneja S, Hsu S. Lindsay S, et al. Disabil Rehabil. 2024 Jun 12:1-20. doi: 10.1080/09638288.2024.2364823. Online ahead of print. Disabil Rehabil. 2024. PMID: 38864302 Review.
PURPOSE: Although the health benefits of early diagnosis and therapeutic approaches for children and youth with autism spectrum disorder (ASD), racial disparities persist. This systematic review explored the experiences of racism and racial disparities in health car …
PURPOSE: Although the health benefits of early diagnosis and therapeutic approaches for children and youth with autism spectrum di
Magnetoencephalography for the pediatric population, indications, acquisition and interpretation for the clinician.
Dmytriw AA, Hadjinicolaou A, Ntolkeras G, Tamilia E, Pesce M, Berto LF, Grant PE, Pang E, Ahtam B. Dmytriw AA, et al. Neuroradiol J. 2024 Jun 12:19714009241260801. doi: 10.1177/19714009241260801. Online ahead of print. Neuroradiol J. 2024. PMID: 38864180 Review.
Finally, we describe the expanding clinical applications of MEG, including its pivotal role in presurgical evaluation of epilepsy patients, presurgical mapping of eloquent cortices (somatosensory and motor cortices, visual and auditory cortices, lateralization of language), its e …
Finally, we describe the expanding clinical applications of MEG, including its pivotal role in presurgical evaluation of epilepsy patients, …
Feasibility and acceptability of autism adapted safety plans: an external pilot randomised controlled trial.
Rodgers J, Cassidy S, Pelton M, Goodwin J, Wagnild J, Bhattarai N, Gordon I, Wilson C, Heslop P, Ogundimu E, O'Connor RC, Ramsay SE, Townsend E, Vale L. Rodgers J, et al. EClinicalMedicine. 2024 Jun 1;73:102662. doi: 10.1016/j.eclinm.2024.102662. eCollection 2024 Jul. EClinicalMedicine. 2024. PMID: 38864075 Free PMC article.
BACKGROUND: Autistic people are a high-risk group for self-harm and suicide. There are no evidence-based suicide prevention interventions developed specifically for autistic people. We undertook a pilot feasibility randomised controlled trial of autism adapte …
BACKGROUND: Autistic people are a high-risk group for self-harm and suicide. There are no evidence-based suicide prevention intervent …
Morita Therapy as a Treatment Approach for Adolescent Autism Spectrum Disorder: A Five-Year Case Report Incorporating Inpatient and Diary Therapy.
Nakamura M. Nakamura M. Cureus. 2024 Jun 5;16(6):e61750. doi: 10.7759/cureus.61750. eCollection 2024 Jun. Cureus. 2024. PMID: 38863770 Free PMC article.
In this report, a five-year course of treatment for a female patient with autism spectrum disorder (ASD) is presented. The patient exhibited dissociation, auditory hallucinations, overmedication, and wrist cutting, leading to multiple admissions to an adolescent war …
In this report, a five-year course of treatment for a female patient with autism spectrum disorder (ASD) is presented. The pat …
Environmental pollution and extreme weather conditions: insights into the effect on mental health.
Tota M, Karska J, Kowalski S, Piątek N, Pszczołowska M, Mazur K, Piotrowski P. Tota M, et al. Front Psychiatry. 2024 May 28;15:1389051. doi: 10.3389/fpsyt.2024.1389051. eCollection 2024. Front Psychiatry. 2024. PMID: 38863619 Free PMC article. Review.
In this review, we aim to summarize the current knowledge on the impact of environmental pollution and extreme weather conditions on mental health, focusing on anxiety spectrum disorders, autism spectrum disorders, schizophrenia, and depression. In air pollution studies, i …
In this review, we aim to summarize the current knowledge on the impact of environmental pollution and extreme weather conditions on mental …
Development and evaluation of a family-child reading picture book on reducing autism spectrum disorder caregivers' psychological stress: a mixed method study.
Yang L, Ye J, Zhu H, Tang Y, Li X. Yang L, et al. Front Psychiatry. 2024 May 8;15:1390430. doi: 10.3389/fpsyt.2024.1390430. eCollection 2024. Front Psychiatry. 2024. PMID: 38863613 Free PMC article.
METHODS: Based on the ADDIE (Analysis, Design, Development, Implementation, and Evaluation) model, we initially did in-depth interviews with 8 caregivers, and conducted field observation in two rehabilitation centers to analyze the daily lives, the empowered components, the emoti …
METHODS: Based on the ADDIE (Analysis, Design, Development, Implementation, and Evaluation) model, we initially did in-depth interviews with …
Case report: hikikomori syndrome in Italy and its link with autistic traits and internet gaming disorder.
Carpita B, Bonelli C, Giovannoni F, Parri F, Gambini M, Nardi B, Amatori G, Cremone IM, Pini S, Dell'Osso L. Carpita B, et al. Front Psychiatry. 2024 May 28;15:1378572. doi: 10.3389/fpsyt.2024.1378572. eCollection 2024. Front Psychiatry. 2024. PMID: 38863612 Free PMC article.
Despite initially considered a culture-bound syndrome, hikikomori syndrome later gained a wider recognition in different countries, ranging from an attempt to take refuge in an idealistic world, when society success' standards are not reached, to a maladaptive coping strategy com …
Despite initially considered a culture-bound syndrome, hikikomori syndrome later gained a wider recognition in different countries, ranging …
Temporal resolution relates to sensory hyperreactivity independently of stimulus detection sensitivity in individuals with autism spectrum disorder.
Kaneko A, Atsumi T, Ide M. Kaneko A, et al. Perception. 2024 Jun 12:3010066241259729. doi: 10.1177/03010066241259729. Online ahead of print. Perception. 2024. PMID: 38863412
Researchers have been focusing on perceptual characteristics of autism spectrum disorder (ASD) in terms of sensory hyperreactivity. ...
Researchers have been focusing on perceptual characteristics of autism spectrum disorder (ASD) in terms of sensory hyperreacti …
A transdiagnostic examination of cognitive heterogeneity in children and adolescents with neurodevelopmental disorders.
Al-Saoud S, Nichols ES, Brossard-Racine M, Wild CJ, Norton L, Duerden EG. Al-Saoud S, et al. Child Neuropsychol. 2024 Jun 11:1-19. doi: 10.1080/09297049.2024.2364957. Online ahead of print. Child Neuropsychol. 2024. PMID: 38863216
Measures of short-term memory, verbal ability, and reasoning were administered to participants with attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD), comorbid ADHD/ASD, and participants without neurodevelopmental disorders (non- …
Measures of short-term memory, verbal ability, and reasoning were administered to participants with attention-deficit/hyperactivity disor
Comparing the Implementation Context for Early Intervention Services Before and During the COVID-19 Pandemic.
Shire SY, Shih W, Chang YC, Kodjoe M, Nodzo S, Kasari C. Shire SY, et al. Prev Sci. 2024 Jun 11. doi: 10.1007/s11121-024-01696-5. Online ahead of print. Prev Sci. 2024. PMID: 38862831
Through secondary data analysis, characteristics of toddlers with autism being served in a publicly funded center-based early intervention program as well as the characteristics of their educators are examined, comparing those who were enrolled in (a) two randomized trials …
Through secondary data analysis, characteristics of toddlers with autism being served in a publicly funded center-based early interve …
Self-administered mindfulness interventions reduce stress in a large, randomized controlled multi-site study.
Sparacio A, IJzerman H, Ropovik I, Giorgini F, Spiessens C, Uchino BN, Landvatter J, Tacana T, Diller SJ, Derrick JL, Segundo J, Pierce JD, Ross RM, Francis Z, LaBoucane A, Ma-Kellams C, Ford MB, Schmidt K, Wong CC, Higgins WC, Stone BM, Stanley SK, Ribeiro G, Fuglestad PT, Jaklin V, Kübler A, Ziebell P, Jewell CL, Kovas Y, Allahghadri M, Fransham C, Baranski MF, Burgess H, Benz ABE, DeSousa M, Nylin CE, Brooks JC, Goldsmith CM, Benson JM, Griffin SM, Dunne S, Davis WE, Watermeyer TJ, Meese WB, Howell JL, Standiford Reyes L, Strickland MG, Dickerson SS, Pescatore S, Skakoon-Sparling S, Wunder ZI, Day MV, Brenton S, Linden AH, Hawk CE, O'Brien LV, Urgyen T, McDonald JS, van der Schans KL, Blocker H, Ng Tseung-Wong C, Jiga-Boy GM. Sparacio A, et al. Nat Hum Behav. 2024 Jun 11. doi: 10.1038/s41562-024-01907-7. Online ahead of print. Nat Hum Behav. 2024. PMID: 38862815
Altered intra- and inter-network connectivity in autism spectrum disorder.
Zhou R, Sun C, Sun M, Ruan Y, Li W, Gao X. Zhou R, et al. Aging (Albany NY). 2024 Jun 10;16. doi: 10.18632/aging.205913. Online ahead of print. Aging (Albany NY). 2024. PMID: 38862259 Free article.
OBJECTIVE: A neurodevelopmental illness termed as the autism spectrum disorder (ASD) is described by social interaction impairments. ...
OBJECTIVE: A neurodevelopmental illness termed as the autism spectrum disorder (ASD) is described by social interaction impair …
Does Gestural Communication Influence Later Spoken Language Ability in Minimally Verbal Autistic Children?
La Valle C, Shen L, Shih W, Kasari C, Shire S, Lord C, Tager-Flusberg H. La Valle C, et al. J Speech Lang Hear Res. 2024 Jun 11:1-14. doi: 10.1044/2024_JSLHR-23-00433. Online ahead of print. J Speech Lang Hear Res. 2024. PMID: 38861424
METHOD: Participants were 50 MV autistic children (40 boys), ages 54-105 months (M = 75.54, SD = 16.45). MV was defined as producing fewer than 20 spontaneous, unique, and socially communicative words. Autism symptom severity (Autism Diagnostic Observation Sc …
METHOD: Participants were 50 MV autistic children (40 boys), ages 54-105 months (M = 75.54, SD = 16.45). MV was defined as producing …
Auditory Challenges and Listening Effort in School-Age Children With Autism: Insights From Pupillary Dynamics During Speech-in-Noise Perception.
Xu S, Zhang H, Fan J, Jiang X, Zhang M, Guan J, Ding H, Zhang Y. Xu S, et al. J Speech Lang Hear Res. 2024 Jun 11:1-44. doi: 10.1044/2024_JSLHR-23-00553. Online ahead of print. J Speech Lang Hear Res. 2024. PMID: 38861391
PURPOSE: This study aimed to investigate challenges in speech-in-noise (SiN) processing faced by school-age children with autism spectrum conditions (ASCs) and their impact on listening effort. ...RESULTS: No main effect of group was found on accuracy rates. Instead, signi …
PURPOSE: This study aimed to investigate challenges in speech-in-noise (SiN) processing faced by school-age children with autism spec …
The Association Between Functional Variants in Long Non-coding RNAs and the Risk of Autism Spectrum Disorder Was Not Mediated by Gut Microbiota.
Zhu K, Xie X, Hou F, Chen Y, Wang H, Jiang Q, Feng Y, Xiao P, Zhang Q, Xiang Z, Fan Y, Wu X, Li L, Song R. Zhu K, et al. Mol Neurobiol. 2024 Jun 11. doi: 10.1007/s12035-024-04276-4. Online ahead of print. Mol Neurobiol. 2024. PMID: 38861233
The effect of functional variants in long non-coding RNA (lncRNA) gene regions on autism spectrum disorder (ASD) remains unclear. The present study aimed to investigate the association of functional variants located in lncRNA genes with the risk of ASD and explore w …
The effect of functional variants in long non-coding RNA (lncRNA) gene regions on autism spectrum disorder (ASD) remains uncle …
Atypical dynamic neural configuration in autism spectrum disorder and its relationship to gene expression profiles.
Shan X, Wang P, Yin Q, Li Y, Wang X, Feng Y, Xiao J, Li L, Huang X, Chen H, Duan X. Shan X, et al. Eur Child Adolesc Psychiatry. 2024 Jun 11. doi: 10.1007/s00787-024-02476-w. Online ahead of print. Eur Child Adolesc Psychiatry. 2024. PMID: 38861168
Although it is well recognized that autism spectrum disorder (ASD) is associated with atypical dynamic functional connectivity patterns, the dynamic changes in brain intrinsic activity over each time point and the potential molecular mechanisms associated with atypi …
Although it is well recognized that autism spectrum disorder (ASD) is associated with atypical dynamic functional connectivity …
Research progress on phosphodiesterase 4 inhibitors in central nervous system diseases.
Adili A, Dilihumaer A, Zhu H, Tang H. Adili A, et al. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2024 Jun 6:1-9. doi: 10.3724/zdxbyxb-2024-0023. Online ahead of print. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2024. PMID: 38860393 Chinese, English.
Alteration of PDE4 activity is the molecular basis of psychosis and cognitive disorders, therefore it is considered as one of the therapeutic targets for schizophrenia. PDE4 inhibitors play a role in depression; Autism spectrum and Huntington's disease by inhibiting the ad …
Alteration of PDE4 activity is the molecular basis of psychosis and cognitive disorders, therefore it is considered as one of the therapeuti …
Case report: Diagnostic challenges in an adolescent case of autistic catatonia.
Nadeem NJ, Moawad A, Howatson S, Ahmed A, Cassell D. Nadeem NJ, et al. Front Psychiatry. 2024 May 27;15:1386949. doi: 10.3389/fpsyt.2024.1386949. eCollection 2024. Front Psychiatry. 2024. PMID: 38859882 Free PMC article.
Catatonia occurs in several conditions including psychotic, affective and neurodevelopmental disorders such as autism spectrum disorder (ASD). ASD is a neurodevelopmental disorder characterized by persistent deficits in communication, social interaction, rest …
Catatonia occurs in several conditions including psychotic, affective and neurodevelopmental disorders such as autism spectrum dis
Optimising the oral midazolam dose for premedication in people with intellectual disabilities and/or autism spectrum disorder.
Higuchi H, Miyake K, Miyake S, Fujimoto M, Nishioka Y, Maeda S, Miyawaki T. Higuchi H, et al. J Appl Res Intellect Disabil. 2024 Jul;37(4):e13265. doi: 10.1111/jar.13265. J Appl Res Intellect Disabil. 2024. PMID: 38859732
BACKGROUND: In people with intellectual disabilities and/or autism spectrum disorder, oral midazolam (OM) is very effective as premedication for facilitating medical treatment. In this retrospective study, we investigated the optimal dosage of OM for premedication. …
BACKGROUND: In people with intellectual disabilities and/or autism spectrum disorder, oral midazolam (OM) is very effective as …
Psychological behavioral therapies to improve autistic children's behaviors during dental visits: A systematic review and meta-analysis.
Pui Ying LP, Hoi Wan FE, Tung Megan CY, Ming LC, McGrath CP, Kar Yung YC. Pui Ying LP, et al. Autism. 2024 Jun 10:13623613241255302. doi: 10.1177/13623613241255302. Online ahead of print. Autism. 2024. PMID: 38859552 Review.
This research review looked at how well different psychological behavioral therapies help improve the behavior of autistic children during dental visits. The researchers studied 18 different studies and found that, on average, about 56% of autistic children were abl …
This research review looked at how well different psychological behavioral therapies help improve the behavior of autistic children d …
Depression and parental distress among caregivers of autistic children: a serial mediator analysis in caregivers of autistic children.
Demirpençe Seçinti D, Diş D, Albayrak ZS, Şen E. Demirpençe Seçinti D, et al. BMC Psychol. 2024 Jun 10;12(1):339. doi: 10.1186/s40359-024-01704-x. BMC Psychol. 2024. PMID: 38858797 Free PMC article.
BACKGROUND: This study aimed to investigate the relationship between the severity of autism, emotional and behavioral problems of autistic children, internalized stigma, depressive symptoms, and primary caregiver parental stress. ...METHOD: Mothers of 93 children wi …
BACKGROUND: This study aimed to investigate the relationship between the severity of autism, emotional and behavioral problems of …
New advances in the diagnosis and treatment of autism spectrum disorders.
Qin L, Wang H, Ning W, Cui M, Wang Q. Qin L, et al. Eur J Med Res. 2024 Jun 10;29(1):322. doi: 10.1186/s40001-024-01916-2. Eur J Med Res. 2024. PMID: 38858682 Free PMC article. Review.
Autism spectrum disorders (ASD) are a group of neurodevelopmental disorders that affect individuals' social interactions, communication skills, and behavioral patterns, with significant individual differences and complex etiology. ...
Autism spectrum disorders (ASD) are a group of neurodevelopmental disorders that affect individuals' social interactions, communicati
Pharmacological modulation of developmental and synaptic phenotypes in human SHANK3 deficient stem cell-derived neuronal models.
Thibaudeau A, Schmitt K, François L, Chatrousse L, Hoffmann D, Cousin L, Weiss A, Vuidel A, Jacob CB, Sommer P, Benchoua A, Wilbertz JH. Thibaudeau A, et al. Transl Psychiatry. 2024 Jun 10;14(1):249. doi: 10.1038/s41398-024-02947-3. Transl Psychiatry. 2024. PMID: 38858349 Free PMC article.
The resulting deficiency of the postsynaptic density scaffolding protein SHANK3 is associated with autism spectrum disorder (ASD). We examined 12 different PMDS patient and CRISPR-engineered stem cell-derived neuronal models and controls and found that reduced expre …
The resulting deficiency of the postsynaptic density scaffolding protein SHANK3 is associated with autism spectrum disorder (A …
Close Relationships Despite the Challenges: Sibling Relationships and Autism.
Trew S. Trew S. J Autism Dev Disord. 2024 Jun 11. doi: 10.1007/s10803-024-06412-4. Online ahead of print. J Autism Dev Disord. 2024. PMID: 38858310
This study explores the experiences of siblings of autistic adolescents within families. Without the novel insights generated from engaging with siblings of autistic adolescents within a qualitative framework, it can be challenging to develop strategies for practici …
This study explores the experiences of siblings of autistic adolescents within families. Without the novel insights generated from en …
Implications of Provider Specialty, Test Type, and Demographic Factors on Genetic Testing Outcomes for Patients with Autism Spectrum Disorder.
Harrington CN, Morales A, Bernstein JA, Calderwood L. Harrington CN, et al. J Autism Dev Disord. 2024 Jun 11. doi: 10.1007/s10803-024-06423-1. Online ahead of print. J Autism Dev Disord. 2024. PMID: 38858309
A minority of patients with autism spectrum disorder (ASD) are offered genetic testing by their providers or referred for genetics evaluation despite published guidelines and consensus statements supporting genetics-informed care for this population. ...
A minority of patients with autism spectrum disorder (ASD) are offered genetic testing by their providers or referred for gene …
Role of Semaphorin 3A in common psychiatric illnesses such as schizophrenia, depression, and anxiety.
Yang Y, Guan W, Sheng XM, Gu HJ. Yang Y, et al. Biochem Pharmacol. 2024 Jun 8:116358. doi: 10.1016/j.bcp.2024.116358. Online ahead of print. Biochem Pharmacol. 2024. PMID: 38857830 Review.
An increasing number of studies show that sema-3A plays important roles in synaptic and dendritic development, which are closely associated with the pathophysiological mechanisms of psychiatric disorders, including schizophrenia, depression, and autism, suggesting the invo …
An increasing number of studies show that sema-3A plays important roles in synaptic and dendritic development, which are closely associated …
Shared behavioural impairments in visual perception and place avoidance across different autism models are driven by periaqueductal grey hypoexcitability in Setd5 haploinsufficient mice.
Burnett LE, Koppensteiner P, Symonova O, Masson T, Vega-Zuniga T, Contreras X, Rülicke T, Shigemoto R, Novarino G, Joesch M. Burnett LE, et al. PLoS Biol. 2024 Jun 10;22(6):e3002668. doi: 10.1371/journal.pbio.3002668. Online ahead of print. PLoS Biol. 2024. PMID: 38857283 Free article.
Despite the diverse genetic origins of autism spectrum disorders (ASDs), affected individuals share strikingly similar and correlated behavioural traits that include perceptual and sensory processing challenges. Notably, the severity of these sensory symptoms is often pred …
Despite the diverse genetic origins of autism spectrum disorders (ASDs), affected individuals share strikingly similar and correlated …
Ideational Praxis, Play, and Playfulness: A Cross-Sectional Study of Autistic Children.
Serrada-Tejeda S, May-Benson TA, Bundy A, Santos-Del-Riego SE, Rodríguez-Pérez MP, Pérez-de-Heredia-Torres M. Serrada-Tejeda S, et al. Am J Occup Ther. 2024 Jul 1;78(4):7804185010. doi: 10.5014/ajot.2024.050397. Am J Occup Ther. 2024. PMID: 38857122
IMPORTANCE: Assessment of praxis skills is an essential aspect of understanding autistic children's development of play and playfulness. OBJECTIVE: To assess the relationship and influence of ideational praxis skills on play skills and playfulness among autistic chi …
IMPORTANCE: Assessment of praxis skills is an essential aspect of understanding autistic children's development of play and playfulne …
Spinal manipulation and mobilisation in paediatrics - an international evidence-based position statement for physiotherapists.
Gross AR, Olson KA, Pool J, Basson A, Clewley D, Dice JL, Milne N. Gross AR, et al. J Man Manip Ther. 2024 Jun 10:1-23. doi: 10.1080/10669817.2024.2332026. Online ahead of print. J Man Manip Ther. 2024. PMID: 38855972 Review.
Cervical and lumbar spine manipulation on children.Spinal manipulation and mobilisation on infants, children, and adolescents for non-musculoskeletal paediatric conditions including asthma, attention deficit hyperactivity disorder, autism spectrum disorder, b …
Cervical and lumbar spine manipulation on children.Spinal manipulation and mobilisation on infants, children, and adolescents for non-muscul …
Impact of smart technology use on sleep quality in individuals with autism spectrum disorder: a mixed-methods investigation.
Abouzed M, Salama B, Gabr A, Elag KA, Soliman M, Elsaadouni N, Elzahab NA. Abouzed M, et al. Front Psychiatry. 2024 May 24;15:1411993. doi: 10.3389/fpsyt.2024.1411993. eCollection 2024. Front Psychiatry. 2024. PMID: 38855644 Free PMC article.
BACKGROUND: Sleep disturbances are common among individuals with autism spectrum disorder (ASD) and can have a negative impact on their daily functioning and core symptoms. ...
BACKGROUND: Sleep disturbances are common among individuals with autism spectrum disorder (ASD) and can have a negative impact …
Rare Case of a 20p13 Duplication Trisomy With Craniostenosis.
Rizea RE, Tataranu LG, Kamel A, Ciurea AV, Gheorghita KL. Rizea RE, et al. Cureus. 2024 Jun 8;16(6):e61949. doi: 10.7759/cureus.61949. eCollection 2024 Jun. Cureus. 2024. PMID: 38855489 Free PMC article.
Here, we present a rare case of an 8-year-old boy diagnosed with trisomy 20, epilepsy with focal seizures of genetic origin, craniosynostosis, type 1 diabetes, and autism spectrum disorder. Duplication 20p is a complex diagnostic and presents a therapeutic challenge …
Here, we present a rare case of an 8-year-old boy diagnosed with trisomy 20, epilepsy with focal seizures of genetic origin, craniosynostosi …
Rich-club organization of whole-brain spatio-temporal multilayer functional connectivity networks.
Zheng J, Cheng Y, Wu X, Li X, Fu Y, Yang Z. Zheng J, et al. Front Neurosci. 2024 May 24;18:1405734. doi: 10.3389/fnins.2024.1405734. eCollection 2024. Front Neurosci. 2024. PMID: 38855440 Free PMC article.
The proposed method was validated in three independent differential analysis experiments: male-female gender difference analysis, analysis of abnormality in patients with autism spectrum disorders (ASD), and individual difference analysis. ...
The proposed method was validated in three independent differential analysis experiments: male-female gender difference analysis, analysis o …
Case report: A Boy with an inability to walk; do not forget about scurvy.
Noor Emilia EM, Said AH. Noor Emilia EM, et al. Malays Fam Physician. 2024 May 14;19:31. doi: 10.51866/cr.590. eCollection 2024. Malays Fam Physician. 2024. PMID: 38855399 Free PMC article.
Scurvy, a condition caused by vitamin C deficiency, is characterized by a syndrome of multisystem disorder due to defective collagen production and antioxidative function. ...Herein, we report a case of an 8-year-old boy with underlying autism spectrum disorder
Scurvy, a condition caused by vitamin C deficiency, is characterized by a syndrome of multisystem disorder due to defective collagen …
Improving Access to Autism Evaluation: A Coordinated Developmental-Behavioral Pediatrics and Pediatric Neurology Diagnostic Pathway.
Braddock B, Turner K, Kumarason K, Bock L, Stumpe K, Wallace M, Heithaus J, Goretzke S, Portnoy S. Braddock B, et al. Mo Med. 2024 May-Jun;121(3):225-230. Mo Med. 2024. PMID: 38854594 Free PMC article.
A shortage of board-certified developmental-behavioral pediatricians generates a bottleneck for children and families who seek autism diagnostic services. Wait time for autism evaluation commonly exceeds a year. ...Parents reported satisfaction with the autism
A shortage of board-certified developmental-behavioral pediatricians generates a bottleneck for children and families who seek autism
MED13 Gene Mutation Related to Autism Spectrum Disorder: A Case Report.
Rivera MD, Aponte SN, Rivera F, Arciniegas NJ, Carlo S. Rivera MD, et al. Cureus. 2024 May 8;16(5):e59904. doi: 10.7759/cureus.59904. eCollection 2024 May. Cureus. 2024. PMID: 38854223 Free PMC article.
This case report highlights an association between the MED13 gene and autism spectrum disorder (ASD). ASD is a neurodevelopmental disorder characterized by impaired social interactions, communication difficulties, and repetitive behaviors. ...
This case report highlights an association between the MED13 gene and autism spectrum disorder (ASD). ASD is a neurodevelopmen …
Sex Differences in Morphine Sensitivity of Neuroligin-3 Knockout Mice.
Brandner DD, Mashal MA, Grissom NM, Rothwell PE. Brandner DD, et al. bioRxiv [Preprint]. 2024 Jun 1:2024.06.01.596965. doi: 10.1101/2024.06.01.596965. bioRxiv. 2024. PMID: 38854153 Free PMC article. Preprint.
For example, studies of male mice carrying autism-associated mutations in neuroligin-3 are over-represented in the literature, including our own prior work showing diminished responses to chronic morphine exposure in male neuroligin-3 knockout mice. ...These results also s …
For example, studies of male mice carrying autism-associated mutations in neuroligin-3 are over-represented in the literature, includ …
Autism gene variants disrupt enteric neuron migration and cause gastrointestinal dysmotility.
McCluskey KE, Stovell KM, Law K, Kostyanovskaya E, Schmidt J, Exner CRT, Dea J, Brimble E, State MW, Willsey AJ, Willsey HR. McCluskey KE, et al. bioRxiv [Preprint]. 2024 May 29:2024.05.28.593642. doi: 10.1101/2024.05.28.593642. bioRxiv. 2024. PMID: 38854068 Free PMC article. Preprint.
The comorbidity of autism spectrum disorders and severe gastrointestinal symptoms is well-established, yet the molecular underpinnings remain unknown. The identification of high-confidence large-effect autism risk genes offers the opportunity to identify convergent, …
The comorbidity of autism spectrum disorders and severe gastrointestinal symptoms is well-established, yet the molecular underpinning …
Cortical determinants of loudness perception and auditory hypersensitivity.
Clayton KK, McGill M, Awwad B, Stecyk KS, Kremer C, Skerleva D, Narayanan DP, Zhu J, Hancock KE, Kujawa SG, Kozin ED, Polley DB. Clayton KK, et al. bioRxiv [Preprint]. 2024 May 30:2024.05.30.596691. doi: 10.1101/2024.05.30.596691. bioRxiv. 2024. PMID: 38853938 Free PMC article. Preprint.
PVN loudness adjustments were "sticky", such that a single bout of 40Hz PVN stimulation sustainably suppressed ACtx sound responsiveness, potentiated feedforward inhibition, and behaviorally desensitized mice to loudness. Sensory sensitivity is a cardinal feature of autism
PVN loudness adjustments were "sticky", such that a single bout of 40Hz PVN stimulation sustainably suppressed ACtx sound responsiveness, po …
Prediction of chronological age from resting-state EEG power in the first three years of life.
An WW, Bhowmik AC, Nelson CA, Wilkinson CL. An WW, et al. medRxiv [Preprint]. 2024 Jun 1:2024.05.31.24308275. doi: 10.1101/2024.05.31.24308275. medRxiv. 2024. PMID: 38853932 Free PMC article. Preprint.
Application of the model to EEG data from infants later diagnosed with autism spectrum disorder or Down syndrome revealed significant underestimations of chronological age. ...
Application of the model to EEG data from infants later diagnosed with autism spectrum disorder or Down syndrome revealed sign …
Posterior default mode network is associated with the social performance in male children with autism spectrum disorder: A dynamic causal modeling analysis based on triple-network model.
Wang L, Qin Y, Yang S, Jin D, Zhu Y, Li X, Li W, Wang Y, Jin C. Wang L, et al. Hum Brain Mapp. 2024 Jun 1;45(8):e26750. doi: 10.1002/hbm.26750. Hum Brain Mapp. 2024. PMID: 38853710 Free PMC article.
The triple-network model has been widely applied in neuropsychiatric disorders including autism spectrum disorder (ASD). However, the mechanism of causal regulations within the triple-network and their relations with symptoms of ASD remains unclear. 81 male ASD and …
The triple-network model has been widely applied in neuropsychiatric disorders including autism spectrum disorder (ASD). Howev …
Differential effectiveness of dietary zinc supplementation with autism-related behaviours in Shank2 knockout mice.
Lee K, Jung Y, Vyas Y, Mills Z, McNamara L, Montgomery JM. Lee K, et al. Philos Trans R Soc Lond B Biol Sci. 2024 Jul 29;379(1906):20230230. doi: 10.1098/rstb.2023.0230. Epub 2024 Jun 10. Philos Trans R Soc Lond B Biol Sci. 2024. PMID: 38853567
The family of SHANK proteins have been shown to be critical in regulating glutamatergic synaptic structure, function and plasticity. SHANK variants are also prevalent in autism spectrum disorders (ASDs), where glutamatergic synaptopathology has been shown to occur in multi …
The family of SHANK proteins have been shown to be critical in regulating glutamatergic synaptic structure, function and plasticity. SHANK v …
Adiponectin rescues synaptic plasticity in the dentate gyrus of a mouse model of Fragile X Syndrome.
Thacker JS, Bettio L, Liang S, Shkolnikov I, Collingridge GL, Christie BR. Thacker JS, et al. Philos Trans R Soc Lond B Biol Sci. 2024 Jul 29;379(1906):20230221. doi: 10.1098/rstb.2023.0221. Epub 2024 Jun 10. Philos Trans R Soc Lond B Biol Sci. 2024. PMID: 38853554
Fragile X syndrome (FXS) is the most common inherited cause of intellectual disability and is the leading known single-gene cause of autism spectrum disorder. Patients with FXS display varied behavioural deficits that include mild to severe cognitive impairments in …
Fragile X syndrome (FXS) is the most common inherited cause of intellectual disability and is the leading known single-gene cause of auti
Perception and behavior toward neuropsychiatric disorders in Saudi Arabia: A systematic review and quality assessment.
Woodman A, Waheed KB, Al-Ansari RY, Ahmad S, Rehman TU, Rasheed M, Jaoua N. Woodman A, et al. Autism. 2024 Jun 9:13623613241258544. doi: 10.1177/13623613241258544. Online ahead of print. Autism. 2024. PMID: 38853384 Review.
However, various groups in Saudi society, including healthcare professionals, medical students, and the general public, lacked knowledge about these health conditions, often leading to stigmatized attitudes and behaviors toward people with attention deficit hyperactivity disor
However, various groups in Saudi society, including healthcare professionals, medical students, and the general public, lacked knowledge abo …
Assessing gastrointestinal symptoms in people with autism: Applying a new measure based on the Rome IV criteria.
Martínez-González AE, Cervin M, Pérez-Sánchez S. Martínez-González AE, et al. Dig Liver Dis. 2024 Jun 7:S1590-8658(24)00777-1. doi: 10.1016/j.dld.2024.05.019. Online ahead of print. Dig Liver Dis. 2024. PMID: 38851976 Free article.
BACKGROUND: People with autism spectrum disorder (ASD) often struggle with gastrointestinal symptoms, implicating alterations of the gut-microbiota-brain axis, which has also been linked to sensory reactivity, pain, and gastro-intestinal symptoms in ASD. ...
BACKGROUND: People with autism spectrum disorder (ASD) often struggle with gastrointestinal symptoms, implicating alterations …
The relationship between hair cortisol concentration and autism diagnosis.
Lin PI, John JR, Masi A, Ong LK, Mathew NE, Moni MA, Eapen V, Walker AK. Lin PI, et al. J Psychiatr Res. 2024 May 30;176:68-76. doi: 10.1016/j.jpsychires.2024.05.052. Online ahead of print. J Psychiatr Res. 2024. PMID: 38850580 Free article.
Here, we investigated whether hair cortisol concentration in a large sample of autistic children differed from non-autistic children, and after accounting for a range of child, parental and family-level characteristics. METHODS: Hair cortisol concentration was measu …
Here, we investigated whether hair cortisol concentration in a large sample of autistic children differed from non-autistic ch …
Do Wechsler intelligence scales predict academic achievement in children with ADHD or autism? A systematic review and meta-analysis.
Marinopoulou M, Åsberg Johnels J, Bornehag CG, Unenge Hallerbäck M, Billstedt E. Marinopoulou M, et al. Appl Neuropsychol Child. 2024 Jun 8:1-15. doi: 10.1080/21622965.2024.2361022. Online ahead of print. Appl Neuropsychol Child. 2024. PMID: 38850546 Review.
Intelligence tests predict academic achievement in typically developed children, however if this is the case also in children with attention-deficit/hyperactivity disorder (ADHD) and/or autism spectrum disorder (ASD) is not clear. ...
Intelligence tests predict academic achievement in typically developed children, however if this is the case also in children with attention …
Five autism-associated transcriptional regulators target shared loci proximal to brain-expressed genes.
Fazel Darbandi S, An JY, Lim K, Page NF, Liang L, Young DM, Ypsilanti AR, State MW, Nord AS, Sanders SJ, Rubenstein JLR. Fazel Darbandi S, et al. Cell Rep. 2024 Jun 7;43(6):114329. doi: 10.1016/j.celrep.2024.114329. Online ahead of print. Cell Rep. 2024. PMID: 38850535 Free article.
Many autism spectrum disorder (ASD)-associated genes act as transcriptional regulators (TRs). ...
Many autism spectrum disorder (ASD)-associated genes act as transcriptional regulators (TRs). ...
Comparison of propofol-esketamine versus propofol-sufentanil for deep sedation and analgesia in children with autism: A randomized double-blind clinical trial.
Miao Y, Zheng M, Li Q, Xiong L, Feng J, Liu X, Fan G, Chaturvedi R, Zhang F, Yin N. Miao Y, et al. Autism Res. 2024 Jun 8. doi: 10.1002/aur.3172. Online ahead of print. Autism Res. 2024. PMID: 38850067
This study aimed to compare the clinical efficacy and safety of propofol-esketamine (PE) versus propofol-sufentanil (PS) for deep sedation and analgesia in children with autism undergoing colonoscopy procedure. One hundred and twenty-four children with autism underg …
This study aimed to compare the clinical efficacy and safety of propofol-esketamine (PE) versus propofol-sufentanil (PS) for deep sedation a …
Identification of novel driver risk genes in CNV loci associated with neurodevelopmental disorders.
Chenlo SA, Gallego X, Durham L, Cáceres M, Guney E, Pérez-Cano L. Chenlo SA, et al. HGG Adv. 2024 Jun 6:100316. doi: 10.1016/j.xhgg.2024.100316. Online ahead of print. HGG Adv. 2024. PMID: 38850022 Free article.
While these types of variations can be commonly found in humans, large and rare CNVs are known to contribute to the development of various neurodevelopmental disorders (NDDs), including autism spectrum disorder (ASD). Nevertheless, given that these NDD-risk CNVs cov …
While these types of variations can be commonly found in humans, large and rare CNVs are known to contribute to the development of various n …
Associations between atypical intracortical myelin content and neuropsychological functions in middle to older aged adults with ASD.
Kohli JS, Linke AC, Martindale IA, Wilkinson M, Kinnear MK, Lincoln AJ, Hau J, Shryock I, Omaleki V, Alemu K, Pedrahita S, Fishman I, Müller RA, Carper RA. Kohli JS, et al. Brain Behav. 2024 Jun;14(6):e3594. doi: 10.1002/brb3.3594. Brain Behav. 2024. PMID: 38849980 Free PMC article.
INTRODUCTION: In vivo myeloarchitectonic mapping based on Magnetic Resonance Imaging (MRI) provides a unique view of gray matter myelin content and offers information complementary to other morphological indices commonly employed in studies of autism spectrum disorder
INTRODUCTION: In vivo myeloarchitectonic mapping based on Magnetic Resonance Imaging (MRI) provides a unique view of gray matter myelin cont …
Genetic and phenotypic heterogeneity in early neurodevelopmental traits in the Norwegian Mother, Father and Child Cohort Study.
Hegemann L, Corfield EC, Askelund AD, Allegrini AG, Askeland RB, Ronald A, Ask H, St Pourcain B, Andreassen OA, Hannigan LJ, Havdahl A. Hegemann L, et al. Mol Autism. 2024 Jun 7;15(1):25. doi: 10.1186/s13229-024-00599-0. Mol Autism. 2024. PMID: 38849897 Free PMC article.
BACKGROUND: Autism and different neurodevelopmental conditions frequently co-occur, as do their symptoms at sub-diagnostic threshold levels. ...RESULTS: We identified 11 latent factors at the phenotypic level. These factors showed associations with diagnoses of autism
BACKGROUND: Autism and different neurodevelopmental conditions frequently co-occur, as do their symptoms at sub-diagnostic threshold …
Sleep disturbances are associated with greater healthcare utilization in children with autism spectrum disorder.
Solomon S, Elbedour L, Meiri G, Michaelovski A, Sadaka Y, Ilan M, Faroy M, Dinstein I, Menashe I. Solomon S, et al. J Neurodev Disord. 2024 Jun 7;16(1):29. doi: 10.1186/s11689-024-09550-z. J Neurodev Disord. 2024. PMID: 38849752 Free PMC article.
BACKGROUND: Sleep disturbances are frequently reported in children with autism spectrum disorder (ASD) and are associated with the severity of co-occurring symptoms. ...STUDY DESIGN: A retrospective, cross-sectional study of 541 children with ASD from the Azrieli Na …
BACKGROUND: Sleep disturbances are frequently reported in children with autism spectrum disorder (ASD) and are associated with …
Effects of (S)-3,4-DCPG, an mGlu8 receptor agonist, on hippocampal long-term potentiation at perforant pathway-dentate gyrus synapses in prenatal valproic acid-induced rat model of autism.
Gholipour P, Ebrahimi Z, Mohammadkhani R, Ghahremani R, Salehi I, Sarihi A, Komaki A, Karimi SA. Gholipour P, et al. Sci Rep. 2024 Jun 7;14(1):13168. doi: 10.1038/s41598-024-63728-y. Sci Rep. 2024. PMID: 38849397 Free PMC article.
Autism spectrum disorder (ASD) is a pervasive neurodevelopmental condition characterized by social interaction deficits, communication impairments, repetitive behaviors, and sensory sensitivities. ...In conclusion, our study advances our understanding of the complex
Autism spectrum disorder (ASD) is a pervasive neurodevelopmental condition characterized by social interaction deficits, commu
Brain development and bioenergetic changes.
Rajan A, Fame RM. Rajan A, et al. Neurobiol Dis. 2024 Jun 5:106550. doi: 10.1016/j.nbd.2024.106550. Online ahead of print. Neurobiol Dis. 2024. PMID: 38849103 Free article. Review.
Bioenergetic-dependent neurodevelopmental disorders include neural tube closure defects, microcephaly, intellectual disability, autism spectrum disorders, epilepsy, mTORopathies, and oncogenic processes. ...
Bioenergetic-dependent neurodevelopmental disorders include neural tube closure defects, microcephaly, intellectual disability, autism
Probing cognitive flexibility in Shank2-deficient mice: Effects of D-cycloserine and NMDAR signaling hub dynamics.
Afzal S, Dürrast N, Hassan I, Soleimanpour E, Tsai PL, Dieterich DC, Fendt M. Afzal S, et al. Prog Neuropsychopharmacol Biol Psychiatry. 2024 Jun 5:111051. doi: 10.1016/j.pnpbp.2024.111051. Online ahead of print. Prog Neuropsychopharmacol Biol Psychiatry. 2024. PMID: 38849086 Free article.
Neurodevelopmental disorders such as autism spectrum disorder (ASD) have a heterogeneous etiology but are largely associated with genetic factors. ...
Neurodevelopmental disorders such as autism spectrum disorder (ASD) have a heterogeneous etiology but are largely associated w …
Exploring the potential of representation and transfer learning for anatomical neuroimaging: Application to psychiatry.
Dufumier B, Gori P, Petiton S, Louiset R, Mangin JF, Grigis A, Duchesnay E. Dufumier B, et al. Neuroimage. 2024 Jun 6;296:120665. doi: 10.1016/j.neuroimage.2024.120665. Online ahead of print. Neuroimage. 2024. PMID: 38848981 Free article.
This paper extensively compares DL and SML prediction capacity on five multi-site problems, including three increasingly complex clinical applications in psychiatry namely schizophrenia, bipolar disorder, and Autism Spectrum Disorder (ASD) diagnosis. To compe …
This paper extensively compares DL and SML prediction capacity on five multi-site problems, including three increasingly complex clinical ap …
Developmental Disruption of Mef2c in Medial Ganglionic Eminence-derived cortical inhibitory interneurons impairs cellular and circuit function.
Ward C, Nasrallah K, Tran D, Sabri E, Vazquez A, Sjulson L, Castillo PE, Batista-Brito R. Ward C, et al. Biol Psychiatry. 2024 Jun 5:S0006-3223(24)01360-X. doi: 10.1016/j.biopsych.2024.05.021. Online ahead of print. Biol Psychiatry. 2024. PMID: 38848814
BACKGROUND: MEF2C is strongly linked to various neurodevelopmental disorders (NDDs) including autism, intellectual disability, schizophrenia, and attention-deficit/hyperactivity. ...
BACKGROUND: MEF2C is strongly linked to various neurodevelopmental disorders (NDDs) including autism, intellectual disability, schizo …
Attention Analysis in Robotic-Assistive Therapy for Children with Autism.
Silva B, Santos L, Barata C, Geminiani A, Fassina G, Gonzalez AR, Ferreira S, Barahona-Correa B, Olivieri I, Pedrocchi A, Santos-Victor J. Silva B, et al. IEEE Trans Neural Syst Rehabil Eng. 2024 Jun 7;PP. doi: 10.1109/TNSRE.2024.3411299. Online ahead of print. IEEE Trans Neural Syst Rehabil Eng. 2024. PMID: 38848230
Children with Autism Spectrum Disorder (ASD) show severe attention deficits, hindering their capacity to acquire new skills. ...This work aims to develop a quantitativemodel, to evaluate the attention response of children with ASD, during robotic-assistive therapeut …
Children with Autism Spectrum Disorder (ASD) show severe attention deficits, hindering their capacity to acquire new skills. . …
The Effect of Naturalistic Developmental Behavioral Interventions and Aided AAC on the Language Development of Children on the Autism Spectrum with Minimal Speech: A Systematic Review and Meta-analysis.
Pope L, Light J, Laubscher E. Pope L, et al. J Autism Dev Disord. 2024 Jun 7. doi: 10.1007/s10803-024-06382-7. Online ahead of print. J Autism Dev Disord. 2024. PMID: 38848009
Both naturalistic developmental behavioral interventions (NDBIs) and augmentative and alternative communication (AAC) have been shown to support the language development of children with a diagnosis of autism spectrum disorder and minimal speech. However, little res …
Both naturalistic developmental behavioral interventions (NDBIs) and augmentative and alternative communication (AAC) have been shown to sup …
Brain Disorder Detection and Diagnosis using Machine Learning and Deep Learning - A Bibliometric Analysis.
Chaki J, Deshpande G. Chaki J, et al. Curr Neuropharmacol. 2024;22(13):e310524230577. doi: 10.2174/1570159X22999240531160344. Curr Neuropharmacol. 2024. PMID: 38847379 Review.
METHODS: We carried out a bibliometric analysis to create an overview of brain disorder detection and diagnosis using machine learning and deep learning. ...The majority of the authors referenced have concentrated on multiclass classification and innovative convolutional n …
METHODS: We carried out a bibliometric analysis to create an overview of brain disorder detection and diagnosis using machine learnin …
Case report: Early use of whole exome sequencing unveils HNRNPU-related neurodevelopmental disorder and answers additional clinical questions through reanalysis.
Dreikorn EN, Munro C, Robin Berman N, Kunovac A, Bellissimo D, Massart MB. Dreikorn EN, et al. Front Genet. 2024 May 23;15:1380552. doi: 10.3389/fgene.2024.1380552. eCollection 2024. Front Genet. 2024. PMID: 38846959 Free PMC article.
This case report chronicles the diagnostic odyssey and resolution of a 27-year-old female with a complex neurodevelopmental disorder (NDD) using Whole Exome Sequencing (WES). The patient presented to a precision medicine clinic with multiple diagnoses including intellectua …
This case report chronicles the diagnostic odyssey and resolution of a 27-year-old female with a complex neurodevelopmental disorder
A Rare Post-Infectious Autoimmune Manifestation of COVID-19.
Kaya F, Alsafdi T, Al-Suleh M. Kaya F, et al. Eur J Case Rep Intern Med. 2024 May 14;11(6):004542. doi: 10.12890/2024_004542. eCollection 2024. Eur J Case Rep Intern Med. 2024. PMID: 38846672 Free PMC article.
Moreover, high levels of neutrophils during infection promote autoimmune disease by releasing cytokine and chemokine cascades that accompany inflammation, and neutrophil extracellular traps regulating immune responses through cell-cell interactions. Furthermore, autism spe …
Moreover, high levels of neutrophils during infection promote autoimmune disease by releasing cytokine and chemokine cascades that accompany …
Comparative Effects of Applied Behavior Analysis on Male and Female Individuals With Autism Spectrum Disorder.
Peterson T, Dodson J, Sherwin R, Strale F Jr. Peterson T, et al. Cureus. 2024 May 7;16(5):e59802. doi: 10.7759/cureus.59802. eCollection 2024 May. Cureus. 2024. PMID: 38846190 Free PMC article.
Introduction Current evidence-based treatments for autism spectrum disorder (ASD) are based on applied behavior analysis (ABA). ...
Introduction Current evidence-based treatments for autism spectrum disorder (ASD) are based on applied behavior analysis (ABA) …
Potassium and calcium channels in different nerve cells act as therapeutic targets in neurological disorders.
Qiu Q, Yang M, Gong D, Liang H, Chen T. Qiu Q, et al. Neural Regen Res. 2024 Jun 3. doi: 10.4103/NRR.NRR-D-23-01766. Online ahead of print. Neural Regen Res. 2024. PMID: 38845230 Free article.
In this review, we focus on the functions of potassium and calcium ion channels in different nerve cells and their involvement in neurological disorders such as Parkinson's disease, Alzheimer's disease, depression, epilepsy, autism, and rare disorders. We also describe sev …
In this review, we focus on the functions of potassium and calcium ion channels in different nerve cells and their involvement in neurologic …
Development of a harmonized sociodemographic and clinical questionnaire for mental health research: A Delphi-method-based consensus recommendation.
Lotfaliany M, Agustini B, Walker AJ, Turner A, Wrobel AL, Williams LJ, Dean OM, Miles S, Rossell SL, Berk M, Mohebbi M; HDQ Investigator Group. Lotfaliany M, et al. Aust N Z J Psychiatry. 2024 Jun 6:48674241253452. doi: 10.1177/00048674241253452. Online ahead of print. Aust N Z J Psychiatry. 2024. PMID: 38845137 Free article. Review.
Measuring self and informant perspectives of Restricted and Repetitive Behaviours (RRBs): psychometric evaluation of the Repetitive Behaviours Questionnaire-3 (RBQ-3) in adult clinical practice and research settgs.
Jones CRG, Livingston LA, Fretwell C, Uljarević M, Carrington SJ, Shah P, Leekam SR. Jones CRG, et al. Mol Autism. 2024 Jun 6;15(1):24. doi: 10.1186/s13229-024-00603-7. Mol Autism. 2024. PMID: 38845057 Free PMC article.
We tested internal consistency, cross-informant reliability and convergent validity of the RBQ-3. In Study 2, a follow-up online study with autistic (N = 151) and non-autistic (N = 151) adults, we further tested internal consistency of the RBQ-3 self-report version. …
We tested internal consistency, cross-informant reliability and convergent validity of the RBQ-3. In Study 2, a follow-up online study with …
Relationship between sex biases in gene expression and sex biases in autism and Alzheimer's disease.
Fass SB, Mulvey B, Chase R, Yang W, Selmanovic D, Chaturvedi SM, Tycksen E, Weiss LA, Dougherty JD. Fass SB, et al. Biol Sex Differ. 2024 Jun 7;15(1):47. doi: 10.1186/s13293-024-00622-2. Biol Sex Differ. 2024. PMID: 38844994 Free PMC article.
We sought to understand why females have higher rates of Alzheimer's disease, and males have higher rates of autism. One idea was that the female brain at baseline may be more similar to an Alzheimer's brain, so it is easier for them to shift into that state (likewise, mal …
We sought to understand why females have higher rates of Alzheimer's disease, and males have higher rates of autism. One idea was tha …
The natural history of progressive myoclonus Ataxia.
van der Veen S, Eggink H, Elting JWJ, Sival D, Verschuuren-Bemelmans CC, De Koning TJ, Tijssen MAJ. van der Veen S, et al. Neurobiol Dis. 2024 Jun 4:106555. doi: 10.1016/j.nbd.2024.106555. Online ahead of print. Neurobiol Dis. 2024. PMID: 38844245 Free article.
Main accompanying neurological dysfunctions included cognitive impairment (62%), epilepsy (38%), autism spectrum disorder (27%), and behavioral problems (18%). Disease progression showed large variability ranging from an epilepsy free PMA phenotype (62%) to evolutio …
Main accompanying neurological dysfunctions included cognitive impairment (62%), epilepsy (38%), autism spectrum disorder (27% …
The investigation of dysregulated visual perceptual organization in adults with autism spectrum disorders with phase-amplitude coupling and directed connectivity.
Sun L. Sun L. PLoS One. 2024 Jun 6;19(6):e0303959. doi: 10.1371/journal.pone.0303959. eCollection 2024. PLoS One. 2024. PMID: 38843176 Free PMC article.
This study examined the possibility that dysregulated alpha-gamma modulation may be crucially involved in aberrant brain functioning in autism spectrum disorder (ASD). Magnetoencephalographic data were recorded from 13 adult participants with ASD and 16 controls. .. …
This study examined the possibility that dysregulated alpha-gamma modulation may be crucially involved in aberrant brain functioning in a
A Review on Autism Spectrum Disorder Screening by Artificial Intelligence Methods.
Jia SJ, Jing JQ, Yang CJ. Jia SJ, et al. J Autism Dev Disord. 2024 Jun 6. doi: 10.1007/s10803-024-06429-9. Online ahead of print. J Autism Dev Disord. 2024. PMID: 38842671
PURPOSE: With the increasing prevalence of autism spectrum disorders (ASD), the importance of early screening and diagnosis has been subject to considerable discussion. ...
PURPOSE: With the increasing prevalence of autism spectrum disorders (ASD), the importance of early screening and diagnosis has been …
Utilising Behavioural and Sensory Profiles and Associated Perinatal Factors to Identify Meaningful Subgroups in Autism Spectrum Disorder.
Shirley J, John JR, Montgomery A, Whitehouse A, Eapen V. Shirley J, et al. J Autism Dev Disord. 2024 Jun 6. doi: 10.1007/s10803-024-06421-3. Online ahead of print. J Autism Dev Disord. 2024. PMID: 38842670
The heterogeneity of autism spectrum disorder (ASD) clinically and aetiologically hinders intervention matching and prediction of outcomes. This study investigated if the behavioural, sensory, and perinatal factor profiles of autistic children could be used t …
The heterogeneity of autism spectrum disorder (ASD) clinically and aetiologically hinders intervention matching and prediction …
The Role of Pathways Early Autism Intervention in Improving Social Skills and Respeto for Young Hispanic Autistic Children.
Kosloski EE, Patel SD, Rollins PR. Kosloski EE, et al. J Autism Dev Disord. 2024 Jun 6. doi: 10.1007/s10803-024-06419-x. Online ahead of print. J Autism Dev Disord. 2024. PMID: 38842669
PURPOSE: We know very little about Hispanic autistic children's response to intervention as, historically, Hispanic children are underrepresented in intervention studies. Pathways parent-mediated early autism intervention is one of the few naturalistic developmental …
PURPOSE: We know very little about Hispanic autistic children's response to intervention as, historically, Hispanic children are unde …
It is More Anxiousness than Role-playing: Social Camouflaging Conceptualization Among Adults on the Autism Spectrum Compared to Persons with Social Anxiety Disorder.
Pyszkowska A. Pyszkowska A. J Autism Dev Disord. 2024 Jun 6. doi: 10.1007/s10803-024-06416-0. Online ahead of print. J Autism Dev Disord. 2024. PMID: 38842668
PURPOSE: Autistic individuals consider social camouflaging, e.g., masking autistic traits or social skills compensation, as exhausting and effortful, often leading to diminished well-being or burnout, as well as adaptive for satisfying social interactions. Developin …
PURPOSE: Autistic individuals consider social camouflaging, e.g., masking autistic traits or social skills compensation, as ex …
Quantitative Expression of Latent Disease Factors in Individuals Associated with Psychopathology Dimensions and Treatment Response.
Zhao S, Lv Q, Zhang G, Zhang J, Wang H, Zhang J, Wang M, Wang Z. Zhao S, et al. Neurosci Bull. 2024 Jun 6. doi: 10.1007/s12264-024-01224-z. Online ahead of print. Neurosci Bull. 2024. PMID: 38842612
Psychiatric comorbidity is common in symptom-based diagnoses like autism spectrum disorder (ASD), attention/deficit hyper-activity disorder (ADHD), and obsessive-compulsive disorder (OCD). ...
Psychiatric comorbidity is common in symptom-based diagnoses like autism spectrum disorder (ASD), attention/deficit hyper-acti …
Enhancing social behavior in an autism spectrum disorder mouse model: investigating the underlying mechanisms of Lactiplantibacillus plantarum intervention.
Chen CM, Wu CC, Kim Y, Hsu WY, Tsai YC, Chiu SL. Chen CM, et al. Gut Microbes. 2024 Jan-Dec;16(1):2359501. doi: 10.1080/19490976.2024.2359501. Epub 2024 Jun 6. Gut Microbes. 2024. PMID: 38841895 Free PMC article.
Autism spectrum disorder (ASD) is a neurodevelopmental disorder affecting over 1% of the global population. ...
Autism spectrum disorder (ASD) is a neurodevelopmental disorder affecting over 1% of the global population. ...
Assistive tools for classifying neurological disorders using fMRI and deep learning: A guide and example.
Warren SL, Khan DM, Moustafa AA. Warren SL, et al. Brain Behav. 2024 Jun;14(6):e3554. doi: 10.1002/brb3.3554. Brain Behav. 2024. PMID: 38841732 Free PMC article.
OBJECTIVES AND METHODS: In this study, we present an introductory guide to some popular DL and fMRI assistive tools. We also create an example autism spectrum disorder (ASD) classification model using assistive tools (e.g., Optuna, GIFT, and the ABIDE preprocessed r …
OBJECTIVES AND METHODS: In this study, we present an introductory guide to some popular DL and fMRI assistive tools. We also create an examp …
Clinical profile of children and adolescents with autism spectrum disorder in Durban, South Africa.
Gangai M, Karim E, Paruk S. Gangai M, et al. S Afr J Psychiatr. 2024 May 14;30:2230. doi: 10.4102/sajpsychiatry.v30i0.2230. eCollection 2024. S Afr J Psychiatr. 2024. PMID: 38841712 Free PMC article.
BACKGROUND: There are often delays in accessing care and diagnosing autism spectrum disorders (ASDs), with little data from Southern Africa on the clinical profile of affected children and adolescents. ...The most common reasons for referral were behavioural problems and s …
BACKGROUND: There are often delays in accessing care and diagnosing autism spectrum disorders (ASDs), with little data from Southern …
Knowledge of autism among students at a South African Institute of Higher Education.
De Jongh M, Mapisa HAM. De Jongh M, et al. Health SA. 2024 May 31;29:2301. doi: 10.4102/hsag.v29i0.2301. eCollection 2024. Health SA. 2024. PMID: 38841352 Free PMC article.
BACKGROUND: Autism is a significant concern because of the increase in the prevalence of the disorder. ...Students were found to have little awareness of autism's prevalence, causes, diagnosing experts, intervention methods and treatment. ...
BACKGROUND: Autism is a significant concern because of the increase in the prevalence of the disorder. ...Students were found …
A Witteveen-Kolk Syndrome Patient with Reflux Disease and a de novo Deletion of the SIN3A Gene.
Uctepe E, Kandemir N, Bir FD, Karhan AN, Tumer S, Ondes EB, Konuskan B, Yesilyurt A. Uctepe E, et al. Mol Syndromol. 2024 Jun;15(3):251-256. doi: 10.1159/000536072. Epub 2024 Jan 30. Mol Syndromol. 2024. PMID: 38841330
INTRODUCTION: The Witteveen-Kolk syndrome (WITKOS) (OMIM: 613406) is a heterogeneous emerging disorder caused by pathogenic variants or microdeletions encompassing the SIN3A gene (SIN3 Transcription Regulator Family Member A). ...Physicians should also be aware of reflux d …
INTRODUCTION: The Witteveen-Kolk syndrome (WITKOS) (OMIM: 613406) is a heterogeneous emerging disorder caused by pathogenic variants …
Bridging the gap: fostering interactive stimming between non-speaking autistic children and their parents.
Chen RSY. Chen RSY. Front Integr Neurosci. 2024 May 22;18:1374882. doi: 10.3389/fnint.2024.1374882. eCollection 2024. Front Integr Neurosci. 2024. PMID: 38841109 Free PMC article.
Non-speaking autistic individuals grapple with the profound impact of the 'double empathy problem' in their daily interactions with speaking others. ...By spotlighting the natural phenomenon of "interactive stimming," a powerful mode of communication among autistic
Non-speaking autistic individuals grapple with the profound impact of the 'double empathy problem' in their daily interactions with s …
The relation between specific motor skills and daily living skills in autistic children and adolescents.
Skaletski EC, Cardona SC, Travers BG. Skaletski EC, et al. Front Integr Neurosci. 2024 May 22;18:1334241. doi: 10.3389/fnint.2024.1334241. eCollection 2024. Front Integr Neurosci. 2024. PMID: 38841108 Free PMC article.
INTRODUCTION: Motor skill difficulties are common in autistic children and are related to daily living skills (DLS). However, it remains unclear which specific motor tasks are most likely to impact overall DLS. ...Our findings support the benefit of considering individual …
INTRODUCTION: Motor skill difficulties are common in autistic children and are related to daily living skills (DLS). However, it rema …
Altered cytokine and chemokine profile linked to autoantibody and pathogen reactivity in mothers of autistic children.
McLellan J, Croen L, Iosif AM, Yoshida C, Ashwood P, Yolken RH, Van de Water J. McLellan J, et al. Front Psychiatry. 2024 May 22;15:1348092. doi: 10.3389/fpsyt.2024.1348092. eCollection 2024. Front Psychiatry. 2024. PMID: 38840945 Free PMC article.
Maternal autoimmunity, and more specifically, the production of specific maternal autoantibodies, has been associated with altered offspring neurodevelopment. Maternal autoantibody-related (MAR) autism is a subtype of autism that is linked to gestational exposure to …
Maternal autoimmunity, and more specifically, the production of specific maternal autoantibodies, has been associated with altered offspring …
Trends in behavioral management techniques for dental treatment of patients with autism spectrum disorder: a 10-year retrospective analysis.
Son G, Oh S, Lee J, Jun S, Kim J, Kim J, Lee J, Han M, Shin J. Son G, et al. J Dent Anesth Pain Med. 2024 Jun;24(3):187-193. doi: 10.17245/jdapm.2024.24.3.187. Epub 2024 May 27. J Dent Anesth Pain Med. 2024. PMID: 38840652 Free PMC article.
BACKGROUND: Patients with autism spectrum disorder (ASD) present challenges in dental treatment cooperation owing to deficits in communication skills and social interaction. ...
BACKGROUND: Patients with autism spectrum disorder (ASD) present challenges in dental treatment cooperation owing to deficits …
Impaired inhibitory control when processing real but not cartoon emotional faces in autistic children: Evidence from an event-related potential study.
Lee HK, Tong SX. Lee HK, et al. Autism Res. 2024 Jun 5. doi: 10.1002/aur.3176. Online ahead of print. Autism Res. 2024. PMID: 38840481
Impaired socioemotional functioning characterizes autistic children, but does weak inhibition control underlie their socioemotional difficulty? ...Moreover, autistic children exhibited a reduced N170 to real face emotions only. ...
Impaired socioemotional functioning characterizes autistic children, but does weak inhibition control underlie their socioemotional d …
Hyper-focus, sticky attention, and springy attention in young autistic children: Associations with sensory behaviors and cognitive ability.
Dwyer P, Sillas A, Prieto M, Camp E, Nordahl CW, Rivera SM. Dwyer P, et al. Autism Res. 2024 Jun 5. doi: 10.1002/aur.3174. Online ahead of print. Autism Res. 2024. PMID: 38840328
The autistic-developed monotropism account suggests that atypical, domain-general attentional hyper-focus on interests is a central aspect of autism, but domain-general attention differences in autism can manifest differently. ...We found no evidence that …
The autistic-developed monotropism account suggests that atypical, domain-general attentional hyper-focus on interests is a central a …
Sex-specific associations of adolescent motherhood with cognitive function, behavioral problems, and autistic-like traits in offspring and the mediating roles of family conflict and altered brain structure.
Ren T, Zhang L, Liu Y, Zhang Q, Sun Y, Zhou W, Huang L, Wang M, Pu Y, Huang R, Chen J, He H, Zhu T, Wang S, Chen W, Zhang Q, Du W, Luo Q, Li F. Ren T, et al. BMC Med. 2024 Jun 5;22(1):226. doi: 10.1186/s12916-024-03442-8. BMC Med. 2024. PMID: 38840198 Free PMC article.
We employed a generalized linear mixed model to investigate the associations of adolescent motherhood with cognitive, behavioral, and autistic-like traits in offspring. We applied an inverse-probability-weighted marginal structural model to examine the potential mediating …
We employed a generalized linear mixed model to investigate the associations of adolescent motherhood with cognitive, behavioral, and aut
BLA-involved circuits in neuropsychiatric disorders.
Ma LH, Li S, Jiao XH, Li ZY, Zhou Y, Zhou CR, Zhou CH, Zheng H, Wu YQ. Ma LH, et al. Ageing Res Rev. 2024 Jun 3;99:102363. doi: 10.1016/j.arr.2024.102363. Online ahead of print. Ageing Res Rev. 2024. PMID: 38838785 Review.
In this review, we summarized the role of BLA-involved circuits in neuropsychiatric disorders including Alzheimer's disease, perioperative neurocognitive disorders, schizophrenia, anxiety disorders, depressive disorders, posttraumatic stress disorders, autism spectrum diso …
In this review, we summarized the role of BLA-involved circuits in neuropsychiatric disorders including Alzheimer's disease, perioperative n …
Phelan-McDermid Syndrome-SHANK3 Related.
Phelan K, Rogers RC, Boccuto L. Phelan K, et al. 2005 May 11 [updated 2024 Jun 6]. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2024. 2005 May 11 [updated 2024 Jun 6]. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2024. PMID: 20301377 Free Books & Documents. Review.
Neurobehavioral characteristics include mouthing or chewing non-food items, decreased perception of pain, and autism spectrum disorder or autistic-like affect and behavior. Some individuals experience regression / loss of skills, epilepsy, ataxic/abnormal gai …
Neurobehavioral characteristics include mouthing or chewing non-food items, decreased perception of pain, and autism spectrum diso
Tactile sensory processing deficits in genetic mouse models of autism spectrum disorder.
Falcão M, Monteiro P, Jacinto L. Falcão M, et al. J Neurochem. 2024 Jun 4. doi: 10.1111/jnc.16135. Online ahead of print. J Neurochem. 2024. PMID: 38837765 Review.
Altered sensory processing is a common feature in autism spectrum disorder (ASD), as recognized in the Diagnostic and Statistical Manual of Mental Disorders (DSM-5). ...
Altered sensory processing is a common feature in autism spectrum disorder (ASD), as recognized in the Diagnostic and Statisti …
Epigenetic underpinnings of the autistic mind: Histone modifications and prefrontal excitation/inhibition imbalance.
Fard YA, Sadeghi EN, Pajoohesh Z, Gharehdaghi Z, Khatibi DM, Khosravifar S, Pishkari Y, Nozari S, Hijazi A, Pakmehr S, Shayan SK. Fard YA, et al. Am J Med Genet B Neuropsychiatr Genet. 2024 Jun 4:e32986. doi: 10.1002/ajmg.b.32986. Online ahead of print. Am J Med Genet B Neuropsychiatr Genet. 2024. PMID: 38837296 Review.
Autism spectrum disorder (ASD) is complex neurobehavioral condition influenced by several cellular and molecular mechanisms that are often concerned with synaptogenesis and synaptic activity. ...
Autism spectrum disorder (ASD) is complex neurobehavioral condition influenced by several cellular and molecular mechanisms th
'If I Don't Have My Support Worker in the Room…': A Multi-perspective Mixed Methods Study of Remote Daily Living Support for Neurodivergent Young Adults.
Löthberg M, Wirström E, Meyer J, Girdler S, Bölte S, Jonsson U. Löthberg M, et al. J Autism Dev Disord. 2024 Jun 5. doi: 10.1007/s10803-024-06425-z. Online ahead of print. J Autism Dev Disord. 2024. PMID: 38837062
Young service users (aged 18 to 29) diagnosed with ADHD and/or autism (n = 35) and support workers (n = 64) from four municipalities in Sweden responded to a survey designed to tap into their lived experiences and views. ...
Young service users (aged 18 to 29) diagnosed with ADHD and/or autism (n = 35) and support workers (n = 64) from four municipalities …
Investigating the increased risk of schizophrenia and bipolar disorders in relatives of ADHD probands using colocalization analysis of common genetic variants.
Peyre H, Iftimovici A, Ellul P, Krebs MO, Delorme R, Baghdadli A, Pignon B, Chaumette B. Peyre H, et al. Eur Child Adolesc Psychiatry. 2024 Jun 5. doi: 10.1007/s00787-024-02479-7. Online ahead of print. Eur Child Adolesc Psychiatry. 2024. PMID: 38836921
BACKGROUND: Relatives of ADHD probands are known to be at increased risk of schizophrenia and bipolar disorder, suggesting shared genetic factors. In this study, we aim to identify shared common risk variants (i.e., Single-Nucleotide Polymorphisms, SNPs) between ADHD and s …
BACKGROUND: Relatives of ADHD probands are known to be at increased risk of schizophrenia and bipolar disorder, suggesting shared gen …
Mechanism of the effect of TREM2 on cognitive function in autistic mice.
Tian Y, Ai R, Xiao X, Liu W, Cheng S, Zhu X. Tian Y, et al. Cell Mol Biol (Noisy-le-grand). 2024 Jun 5;70(6):66-72. doi: 10.14715/cmb/2024.70.6.11. Cell Mol Biol (Noisy-le-grand). 2024. PMID: 38836680
This study aimed to investigate the mechanism of the effect of TREM2 on cognitive function in autistic mice. TREM2 overexpression and knockdown viruses were given to autism spectrum disorder (ASD) mice and BV2 microglia cell line. ...
This study aimed to investigate the mechanism of the effect of TREM2 on cognitive function in autistic mice. TREM2 overexpression and …
Abnormal Development of the Corpus Callosum in Autism Spectrum Disorder: An MRI Study.
Badhe S, Nivins S, Kulkarni P, Jose A, Manek D, Badhe S, Sane H, Gokulchandran N, Badhe P, Sharma A. Badhe S, et al. Top Magn Reson Imaging. 2024 Jun 4;33(3):e0312. doi: 10.1097/RMR.0000000000000312. eCollection 2024 Jun 1. Top Magn Reson Imaging. 2024. PMID: 38836588
BACKGROUND: Altered size in the corpus callosum (CC) has been reported in individuals with autism spectrum disorder (ASD), but few studies have investigated younger children. ...
BACKGROUND: Altered size in the corpus callosum (CC) has been reported in individuals with autism spectrum disorder (ASD), but …
4-Ethylphenyl Sulfate Detection by an Electrochemical Sensor Based on a MoS2 Nanosheet-Modified Molecularly Imprinted Biopolymer.
Archana, Kumar A, Solanki PR. Archana, et al. ACS Appl Bio Mater. 2024 Jun 5. doi: 10.1021/acsabm.4c00227. Online ahead of print. ACS Appl Bio Mater. 2024. PMID: 38836520
One of the gut-derived uremic toxins 4-ethylphenyl sulfate (4-EPS) exhibits significantly elevated plasma levels in chronic kidney diseases and autism, and its early quantification in bodily fluids is important. ...
One of the gut-derived uremic toxins 4-ethylphenyl sulfate (4-EPS) exhibits significantly elevated plasma levels in chronic kidney diseases …
Disease-Associated Variants in GRIN1, GRIN2A and GRIN2B genes: Insights into NMDA Receptor Structure, Function, and Pathophysiology.
Korinek M, Serra MC, Abdel Rahman F, Dobrovolski M, Kuchtiak V, Abramova V, Fili K, Tomovic E, Hrcka Krausova B, Krusek J, Cerny J, Vyklicky L, Balik A. Korinek M, et al. Physiol Res. 2024 May 31. Online ahead of print. Physiol Res. 2024. PMID: 38836461 Free article.
Rare or de-novo variants in GRIN genes encoding NMDAR subunits have been associated with neurodevelopmental disorders characterized by intellectual disability, developmental delay, autism, schizophrenia, or epilepsy. In recent years, some disease-associated variants in GRI …
Rare or de-novo variants in GRIN genes encoding NMDAR subunits have been associated with neurodevelopmental disorders characterized by intel …
Inextricably tied: Nonbinary autistic individuals' views on how their gender identity and autism are connected.
Voltaire S, Steinberg H, Garfield T, Chvasta K, Ardeleanu K, Brown M, Shea L. Voltaire S, et al. Autism. 2024 Jun 5:13623613241257600. doi: 10.1177/13623613241257600. Online ahead of print. Autism. 2024. PMID: 38836348
This study explores the experiences and identities of nonbinary autistic people. The relationship between autistic and nonbinary identities has not been researched in detail. Few studies focus specifically on nonbinary autistic adults. We interviewed 44 nonbi …
This study explores the experiences and identities of nonbinary autistic people. The relationship between autistic and nonbina …
Body-Focused Repetitive Behaviors in Patients with FOXP1 Syndrome: An International Cross-Sectional Survey-Based Study.
Curtis KL, Lipner SR. Curtis KL, et al. Skin Appendage Disord. 2024 Jun;10(3):229-231. doi: 10.1159/000537906. Epub 2024 Apr 2. Skin Appendage Disord. 2024. PMID: 38835719
INTRODUCTION: FOXP1 syndrome is a rare neurodevelopmental disorder due to forkhead box protein 1 (FOXP1) gene mutations and is associated with intellectual disability, dysmorphic features, and autism spectrum disorder. ...METHODS: A validated survey assessing …
INTRODUCTION: FOXP1 syndrome is a rare neurodevelopmental disorder due to forkhead box protein 1 (FOXP1) gene mutations and is associ …
Beyond words: an investigation of fine motor skills and the verbal communication spectrum in autism.
Simarro Gonzalez M, Ni G, Lam V, Demopoulos C. Simarro Gonzalez M, et al. Front Psychiatry. 2024 May 21;15:1379307. doi: 10.3389/fpsyt.2024.1379307. eCollection 2024. Front Psychiatry. 2024. PMID: 38835552 Free PMC article.
INTRODUCTION: This study investigated the associations between fine motor skills and expressive verbal abilities in a group of 97 autistic participants (age 8-17, mean=12.41) and 46 typically developing youth (age 8-17, mean=12.48). ...Based on prior research, we hypothesi …
INTRODUCTION: This study investigated the associations between fine motor skills and expressive verbal abilities in a group of 97 autisti
Augmentative and alternative communication in autism spectrum disorder: transitioning from letter board to iPad - a case study.
Mavritsakis D. Mavritsakis D. Front Psychiatry. 2024 May 21;15:1345447. doi: 10.3389/fpsyt.2024.1345447. eCollection 2024. Front Psychiatry. 2024. PMID: 38835547 Free PMC article.
This case study examines the effective use of Augmentative and Alternative Communication (AAC) tools in enhancing communication skills in a 15-year-old male with Autism Spectrum Disorder (ASD). Initially exhibiting non-verbal tendencies, the subject experienced sign …
This case study examines the effective use of Augmentative and Alternative Communication (AAC) tools in enhancing communication skills in a …
European Autism GEnomics Registry (EAGER): protocol for a multicentre cohort study and registry.
Bloomfield M, Lautarescu A, Heraty S, Douglas S, Violland P, Plas R, Ghosh A, Van den Bosch K, Eaton E, Absoud M, Battini R, Blázquez Hinojosa A, Bolshakova N, Bölte S, Bonanni P, Borg J, Calderoni S, Calvo Escalona R, Castelo-Branco M, Castro-Fornieles J, Caro P, Cliquet F, Danieli A, Delorme R, Elia M, Hempel M, Leblond CS, Madeira N, McAlonan G, Milone R, Molloy CJ, Mouga S, Montiel V, Pina Rodrigues A, Schaaf CP, Serrano M, Tammimies K, Tye C, Vigevano F, Oliveira G, Mazzone B, O'Neill C, Pender J, Romero V, Tillmann J, Oakley B, Murphy DGM, Gallagher L, Bourgeron T, Chatham C, Charman T. Bloomfield M, et al. BMJ Open. 2024 Jun 4;14(6):e080746. doi: 10.1136/bmjopen-2023-080746. BMJ Open. 2024. PMID: 38834317 Free PMC article.
Many autistic people have unmet healthcare needs that could be served by genomics-informed research and clinical trials. The primary aim of the European Autism GEnomics Registry (EAGER) is to establish a registry of participants with a diagnosis of autism or …
Many autistic people have unmet healthcare needs that could be served by genomics-informed research and clinical trials. The primary …
Investigating low birth weight and preterm birth as potential mediators in the relationship between prenatal infections and early child development: a linked administrative health data analysis.
Hardie I, Murray A, King J, Hall HA, Okelo K, Luedecke E, Marryat L, Thompson L, Minnis H, Lombardo M, Wilson P, Auyeung B. Hardie I, et al. J Epidemiol Community Health. 2024 Jun 4:jech-2023-221826. doi: 10.1136/jech-2023-221826. Online ahead of print. J Epidemiol Community Health. 2024. PMID: 38834230 Free article.
Autism Spectrum Disorders: Etiology, Epidemiology, and Challenges for Public Health.
Ostrowski J, Religioni U, Gellert B, Sytnik-Czetwertyński J, Pinkas J. Ostrowski J, et al. Med Sci Monit. 2024 Jun 4;30:e944161. doi: 10.12659/MSM.944161. Med Sci Monit. 2024. PMID: 38833427 Free PMC article. Review.
Autism spectrum disorder (ASD) is a growing public health problem. American psychiatrist Leo Kanner is considered the "father of autism." ASD encompasses a range of neurodevelopmental disorders that last throughout life. ...
Autism spectrum disorder (ASD) is a growing public health problem. American psychiatrist Leo Kanner is considered the "father
Valproate Use During Spermatogenesis and Risk to Offspring.
Christensen J, Trabjerg BB, Dreier JW. Christensen J, et al. JAMA Netw Open. 2024 Jun 3;7(6):e2414709. doi: 10.1001/jamanetworkopen.2024.14709. JAMA Netw Open. 2024. PMID: 38833248 Free PMC article.
When comparing the risk among valproate-exposed children with that among unexposed children, the ARR of major congenital malformations was 0.89 (95% CI, 0.67-1.18), the AHR of neurodevelopmental disorders was 1.10 (95% CI, 0.88-1.37), and the AHR of autism spectrum diso
When comparing the risk among valproate-exposed children with that among unexposed children, the ARR of major congenital malformations was 0 …
Results from a Pilot Randomized Controlled Trial of a Single-Session Growth-Mindset Intervention for Internalizing Symptoms in Autistic Youth.
Gerber AH, Nahmias A, Schleider JL, Lerner MD. Gerber AH, et al. J Autism Dev Disord. 2024 Jun 4. doi: 10.1007/s10803-024-06341-2. Online ahead of print. J Autism Dev Disord. 2024. PMID: 38833031
Autistic youth experience elevated rates of co-occurring internalizing symptoms. ...One promising option is a relatively new class of evidence-based treatments, single-session interventions (SSIs), however, no study has examined SSIs for depression symptoms in autistic
Autistic youth experience elevated rates of co-occurring internalizing symptoms. ...One promising option is a relatively new class of
Autism Symptom Presentation and Hierarchical Models of Intelligence.
Levine MA, Chen H, Wodka EL, Caffo BS, Ewen JB. Levine MA, et al. J Autism Dev Disord. 2024 Jun 4. doi: 10.1007/s10803-024-06411-5. Online ahead of print. J Autism Dev Disord. 2024. PMID: 38833030
METHOD: We examined correlations between autism diagnostic symptom magnitude (Autism Diagnostic Observational Schedule; ADOS) and a hierarchical statistical model of intelligence. ...Known cohort effects in the relationship between categorical autism diagnosi …
METHOD: We examined correlations between autism diagnostic symptom magnitude (Autism Diagnostic Observational Schedule; ADOS) …
Sleeping Sound Autism Spectrum Disorder (ASD): Cost-Effectiveness of a Brief Behavioural Sleep Intervention in Primary School-Aged Autistic Children.
Engel L, Chiotelis O, Papadopoulos N, Hiscock H, Howlin P, McGillivray J, Bellows ST, Rinehart N, Mihalopoulos C. Engel L, et al. J Autism Dev Disord. 2024 Jun 4. doi: 10.1007/s10803-024-06422-2. Online ahead of print. J Autism Dev Disord. 2024. PMID: 38833029
Disordered sleep is common in autistic children. This study aimed to evaluate the cost-effectiveness of a brief behavioural sleep intervention, the 'Sleeping Sound intervention', in primary school-aged autistic children in Australia. ...The Sleeping Sound interventi …
Disordered sleep is common in autistic children. This study aimed to evaluate the cost-effectiveness of a brief behavioural sleep int …
Screening Options in Autism Telediagnosis: Examination of TAP, M-CHAT-R, and DCI Concordance and Predictive Value in a Telediagnostic Model.
Weitlauf AS, Foster T, Slaughter JC, Fleck M, Harris J, Coffield C, Simcoe K, Baggett J, Stainbrook A, Warren ZE. Weitlauf AS, et al. J Autism Dev Disord. 2024 Jun 4. doi: 10.1007/s10803-024-06427-x. Online ahead of print. J Autism Dev Disord. 2024. PMID: 38833028
Tele-assessment of autism in early childhood has increased. However, it is unclear how autism screening tools (M-CHAT-R, DCI) function as part of tele-assessment and relate to a commonly used tele-assessment instrument, the TAP. 361 families from a clinically referr …
Tele-assessment of autism in early childhood has increased. However, it is unclear how autism screening tools (M-CHAT-R, DCI) …
Explaining deep learning-based representations of resting state functional connectivity data: focusing on interpreting nonlinear patterns in autism spectrum disorder.
Kim YG, Ravid O, Zheng X, Kim Y, Neria Y, Lee S, He X, Zhu X. Kim YG, et al. Front Psychiatry. 2024 May 20;15:1397093. doi: 10.3389/fpsyt.2024.1397093. eCollection 2024. Front Psychiatry. 2024. PMID: 38832332 Free PMC article.
This paper aims to address this gap by developing explainable VAE models and testing their utility using rs-fMRI data in autism spectrum disorder (ASD). METHODS: One-thousand one hundred and fifty participants (601 healthy controls [HC] and 549 patients with ASD) we …
This paper aims to address this gap by developing explainable VAE models and testing their utility using rs-fMRI data in autism spect …
Intellectual disability and autism prevalence in Western Australia: impact of the NDIS.
Bourke J, Sanders R, Jones J, Ranjan M, Wong K, Leonard H. Bourke J, et al. Front Psychiatry. 2024 May 20;15:1359505. doi: 10.3389/fpsyt.2024.1359505. eCollection 2024. Front Psychiatry. 2024. PMID: 38832329 Free PMC article.
INTRODUCTION: Estimates of the prevalence of intellectual disability or autism spectrum disorder (ASD) may vary depending on the methodology, geographical location, and sources of ascertainment. ...
INTRODUCTION: Estimates of the prevalence of intellectual disability or autism spectrum disorder (ASD) may vary depending on t …
Hyperventilation Syndrome and Hypocalcemia: A Unique Case in Autism Spectrum Disorder.
Kamboj R, Singh A, Ketha D, Das A, Chaudhary SM, Idris H, Mallipaddi MC. Kamboj R, et al. Cureus. 2024 May 4;16(5):e59639. doi: 10.7759/cureus.59639. eCollection 2024 May. Cureus. 2024. PMID: 38832161 Free PMC article.
This case report delves into the rare occurrence of hyperventilation syndrome (HVS) with hypocalcemia in an 18-year-old female diagnosed with autism spectrum disorder (ASD). The rare occurrence highlights the importance of recognizing the potential association betwe …
This case report delves into the rare occurrence of hyperventilation syndrome (HVS) with hypocalcemia in an 18-year-old female diagnosed wit …
Effect of intrahippocampal microinjection of VU0155041, a positive allosteric modulator of mGluR4, on long term potentiation in a valproic acid-induced autistic male rat model.
Ebrahimi Z, Gholipour P, Mohammadkhani R, Ghahremani R, Sarihi A, Komaki A, Salehi I, Karimi SA. Ebrahimi Z, et al. IBRO Neurosci Rep. 2024 May 22;16:629-634. doi: 10.1016/j.ibneur.2024.05.005. eCollection 2024 Jun. IBRO Neurosci Rep. 2024. PMID: 38832089 Free PMC article.
The precise cause of autism spectrum disorder (ASD) is not fully understood. Despite the involvement of glutamatergic dysregulation in autism, the specific contribution of mGlu4 receptors to synaptic plasticity remains unclear. Using the positive allosteric m …
The precise cause of autism spectrum disorder (ASD) is not fully understood. Despite the involvement of glutamatergic dysregul …
Discrimination sensitivity of visual shapes sharpens in autistic adults but only after explicit category learning.
Van Overwalle J, Geusens B, Van der Donck S, Boets B, Wagemans J. Van Overwalle J, et al. Mol Autism. 2024 Jun 3;15(1):23. doi: 10.1186/s13229-024-00604-6. Mol Autism. 2024. PMID: 38831439 Free PMC article.
RESULTS: Before training, NT participants immediately revealed a categorical tuning of discrimination, unlike ASC participants who showed largely similar discrimination sensitivity across the stimuli. During training, both autistic and non-autistic participants were …
RESULTS: Before training, NT participants immediately revealed a categorical tuning of discrimination, unlike ASC participants who showed la …
A Systematic Review of Gender Dysphoria Measures in Autistic Samples.
Mears K, Rai D, Shah P, Cooper K, Ashwin C. Mears K, et al. Arch Sex Behav. 2024 Jun 3. doi: 10.1007/s10508-024-02896-4. Online ahead of print. Arch Sex Behav. 2024. PMID: 38831234
Results showed that seven different measures of GD characteristics have been used with autistic samples and that the studies consistently reported a greater number of GD characteristics and a greater severity of GD in autistic compared to non-autistic samples …
Results showed that seven different measures of GD characteristics have been used with autistic samples and that the studies consiste …
Cell- and pathway-specific disruptions in the accumbens of Fragile X mouse.
Giua G, Pereira-Silva J, Caceres-Rodriguez A, Lassalle O, Chavis P, Manzoni OJ. Giua G, et al. J Neurosci. 2024 Jun 3:e1587232024. doi: 10.1523/JNEUROSCI.1587-23.2024. Online ahead of print. J Neurosci. 2024. PMID: 38830765
Fragile X syndrome (FXS) is a genetic cause of intellectual disability and autism spectrum disorder (ASD), associated with social deficits. The mesocorticolimbic system, which includes the prefrontal cortex (PFC), basolateral amygdala (BLA), and nucleus accumbens co …
Fragile X syndrome (FXS) is a genetic cause of intellectual disability and autism spectrum disorder (ASD), associated with soc …
Trans-synaptic association of vesicular zinc transporter 3 and Shank3 supports synapse-specific dendritic spine structure and function in mouse auditory cortex.
Manning A, Bender PTR, Boyd-Pratt H, Mendelson BZ, Hruska M, Anderson CT. Manning A, et al. J Neurosci. 2024 Jun 3:e0619242024. doi: 10.1523/JNEUROSCI.0619-24.2024. Online ahead of print. J Neurosci. 2024. PMID: 38830758
Alterations in ZnT3 are implicated in multiple neurodevelopmental disorders, and ZnT3 knock-out (KO) mice - which lack synaptic zinc - show behavioral deficits associated with autism spectrum disorder and schizophrenia. Using male and female mice, we show that ZnT3 …
Alterations in ZnT3 are implicated in multiple neurodevelopmental disorders, and ZnT3 knock-out (KO) mice - which lack synaptic zinc - show …
Taurine Improved Autism-Like Behaviours and Defective Neurogenesis of the Hippocampus in BTBR Mice through the PTEN/mTOR/AKT Signalling Pathway.
Xiaoyan H, Zhaoxi Y, Lingli Z, Jinyuan C, Wen Q. Xiaoyan H, et al. Folia Biol (Praha). 2024;70(1):45-52. doi: 10.14712/fb2024070010045. Folia Biol (Praha). 2024. PMID: 38830122 Free article.
Effective treatment of patients with autism spectrum disorder (ASD) is still absent so far. Taurine exhibits therapeutic effects towards the autism-like behaviour in ASD model animals. ...In conclusion, taurine reduced the autism-like behaviour in part …
Effective treatment of patients with autism spectrum disorder (ASD) is still absent so far. Taurine exhibits therapeutic effec …
Microcephaly type 22 and autism spectrum disorder: A case report and review of literature.
Ma J, Liu Y, Zhao K. Ma J, et al. Dialogues Clin Neurosci. 2024;26(1):24-27. doi: 10.1080/19585969.2024.2359918. Epub 2024 Jun 3. Dialogues Clin Neurosci. 2024. PMID: 38829782 Free PMC article. Review.
INTRODUCTION: Autism Spectrum Disorder (ASD) is a complex neurodevelopmental disorder with a multifaceted etiology. ...
INTRODUCTION: Autism Spectrum Disorder (ASD) is a complex neurodevelopmental disorder with a multifaceted etiology. ...
CELF2 Deficiency Demonstrates Autism-Like Behaviors and Interferes with Late Development of Cortical Neurons in Mice.
Duan X, Peng X, Jia X, Tan S, Guo H, Tan J, Hu Z. Duan X, et al. Mol Neurobiol. 2024 Jun 3. doi: 10.1007/s12035-024-04250-0. Online ahead of print. Mol Neurobiol. 2024. PMID: 38829512
CELF2 variants have been linked to neurodevelopmental disorders (NDD), including autism spectrum disorder (ASD). However, the molecular mechanisms remain unclear. ...Our study delineated the behavioral and neurodevelopmental phenotypes of Celf2, suggesting its poten …
CELF2 variants have been linked to neurodevelopmental disorders (NDD), including autism spectrum disorder (ASD). However, the …
The double empathy problem: A derivation chain analysis and cautionary note.
Livingston LA, Hargitai LD, Shah P. Livingston LA, et al. Psychol Rev. 2024 Jun 3. doi: 10.1037/rev0000468. Online ahead of print. Psychol Rev. 2024. PMID: 38829337
., clinical practice). It is most popular in research on conditions, like autism, which are characterized by social cognitive difficulties. ...
., clinical practice). It is most popular in research on conditions, like autism, which are characterized by social cognitive difficu …
The Association Between Coping Strategies and Psychological and Emotional Distress Among Health Care Providers Caring for Autistic Children in Jordan.
Abu Khait A, Menger A, Hamdan-Mansour AM, Aldalaykeh M, Hamaideh SH, Al-Mrayat YD, Nusair H. Abu Khait A, et al. West J Nurs Res. 2024 Jun 3:1939459241254782. doi: 10.1177/01939459241254782. Online ahead of print. West J Nurs Res. 2024. PMID: 38829033
BACKGROUND: Health care providers (HCPs) caring for autistic children report more perceived psychological and emotional distress related to their job. ...OBJECTIVE: This study aimed to examine the association between coping strategies (problem-focused, emotion-focused, and …
BACKGROUND: Health care providers (HCPs) caring for autistic children report more perceived psychological and emotional distress rela …
'A certain magic' - autistic adults' experiences of interacting with other autistic people and its relation to Quality of Life: A systematic review and thematic meta-synthesis.
Watts G, Crompton C, Grainger C, Long J, Botha M, Somerville M, Cage E. Watts G, et al. Autism. 2024 Jun 3:13623613241255811. doi: 10.1177/13623613241255811. Online ahead of print. Autism. 2024. PMID: 38829019 Free article.
Research has suggested that autistic people enjoy spending time with other autistic people and find them easier to talk to. We wanted to find out what autistic people say about spending time with other autistic people and whether this makes their life …
Research has suggested that autistic people enjoy spending time with other autistic people and find them easier to talk to. We …
ECHO Autism Washington: Autism Diagnostic Evaluations in Primary Care.
Gerdts J, Casagrande KA, Bateman KJ, Hudac CM, Bravo A, Mancini J, Mannheim J, Ogata B, Orville K, Stobbe GA. Gerdts J, et al. Clin Pediatr (Phila). 2024 Jun 3:99228241255866. doi: 10.1177/00099228241255866. Online ahead of print. Clin Pediatr (Phila). 2024. PMID: 38828759
ECHO (Extensions for Community Healthcare Outcomes) Autism is a telementoring learning model to increase community capacity for autism-related health care. ...Overall, 1 year of ECHO Autism Washington participation led to significant changes in autism
ECHO (Extensions for Community Healthcare Outcomes) Autism is a telementoring learning model to increase community capacity for au
Autistic adults exhibit typical sensitivity to changes in interpersonal distance.
Bunce C, Gehdu BK, Press C, Gray KLH, Cook R. Bunce C, et al. Autism Res. 2024 Jun 3. doi: 10.1002/aur.3164. Online ahead of print. Autism Res. 2024. PMID: 38828663
The visual processing differences seen in autism often impede individuals' visual perception of the social world. ...As expected, however, the autistic observers showed clear signs of impaired face recognition. ...
The visual processing differences seen in autism often impede individuals' visual perception of the social world. ...As expected, how …
Loneliness in daily life: A comparison between youths with autism spectrum disorders and 22q11.2 deletion syndrome (22q11DS).
Feller C, Ilen L, Eliez S, Schneider M. Feller C, et al. Autism Res. 2024 Jun 3. doi: 10.1002/aur.3173. Online ahead of print. Autism Res. 2024. PMID: 38828648
Loneliness is therefore important to investigate in neurodevelopmental populations known for having difficulties in the social sphere. This co-registered study involved 48 youths with autism spectrum disorders (ASD), 54 youths with 22q11.2 deletion syndrome (22q11DS) and 6 …
Loneliness is therefore important to investigate in neurodevelopmental populations known for having difficulties in the social sphere. This …
Language growth in verbal autistic children from 5 to 11 years.
Brignell A, Williams KJ, Reilly S, Morgan AT. Brignell A, et al. Autism Res. 2024 Jun 3. doi: 10.1002/aur.3171. Online ahead of print. Autism Res. 2024. PMID: 38828606
To examine predictors and growth in language for verbal autistic and non-autistic children with/without low language from 4 to 11 years. ...Groups were delineated on baseline assessment at 4 years. Non-autistic and autistic children with low language h …
To examine predictors and growth in language for verbal autistic and non-autistic children with/without low language from 4 to …
Assessing the impact of repetitive transcranial magnetic stimulation on effective connectivity in autism spectrum disorder: An initial exploration using TMS-EEG analysis.
Yang Y, Song P, Wang Y. Yang Y, et al. Heliyon. 2024 May 22;10(11):e31746. doi: 10.1016/j.heliyon.2024.e31746. eCollection 2024 Jun 15. Heliyon. 2024. PMID: 38828287 Free PMC article.
Initial indications propose that repetitive transcranial magnetic stimulation (rTMS) could mitigate clinical manifestations in patients with autism spectrum disorder (ASD). Nevertheless, the precise mechanisms responsible for these therapeutic and behavioral outcome …
Initial indications propose that repetitive transcranial magnetic stimulation (rTMS) could mitigate clinical manifestations in patients with …
Harmonizing data on correlates of sleep in children within and across neurodevelopmental disorders: lessons learned from an Ontario Brain Institute cross-program collaboration.
McPhee PG, Vaccarino AL, Naska S, Nylen K, Santisteban JA, Chepesiuk R, Andrade A, Georgiades S, Behan B, Iaboni A, Wan F, Aimola S, Cheema H, Gorter JW. McPhee PG, et al. Front Neuroinform. 2024 May 17;18:1385526. doi: 10.3389/fninf.2024.1385526. eCollection 2024. Front Neuroinform. 2024. PMID: 38828185 Free PMC article.
Three collaborative research networks contributed demographic data and data pertaining to sleep, internalizing symptoms, health-related quality of life, and severity of disorder for children with six different NDDs: autism spectrum disorder; attention deficit …
Three collaborative research networks contributed demographic data and data pertaining to sleep, internalizing symptoms, health-related qual …
A transdiagnostic approach to neurodiversity in a representative population sample: The N+ 4 model.
Apperly IA, Lee R, van der Kleij SW, Devine RT. Apperly IA, et al. JCPP Adv. 2024 Feb 1;4(2):e12219. doi: 10.1002/jcv2.12219. eCollection 2024 Jun. JCPP Adv. 2024. PMID: 38827989 Free PMC article.
METHOD: The present work examines broader phenotypes using seven widely used self-report assessments of traits associated with autism, ADHD, dyslexia, Developmental Coordination Disorder/dyspraxia, tic disorders/Tourette's, cortical hyperexcitability associated with …
METHOD: The present work examines broader phenotypes using seven widely used self-report assessments of traits associated with autism
Bifactor models of psychopathology using multi-informant and multi-instrument dimensional measures in the ABCD study.
Jacobs GR, Ameis SH, Szatmari P, Haltigan JD, Voineskos AN. Jacobs GR, et al. JCPP Adv. 2024 Feb 26;4(2):e12228. doi: 10.1002/jcv2.12228. eCollection 2024 Jun. JCPP Adv. 2024. PMID: 38827988 Free PMC article.
Using exploratory bifactor methods, this study investigated a comprehensive and representative structure of psychopathology in children to better understand how psychotic-like experiences (PLEs), autism spectrum disorder (ASD) symptoms, impulsivity, and sensitivity …
Using exploratory bifactor methods, this study investigated a comprehensive and representative structure of psychopathology in children to b …
Validity of the multidimensional assessment profile of disruptive behavior in autistic toddlers.
Fipp-Rosenfield H, Grauzer J, Roberts MY, Kaat AJ. Fipp-Rosenfield H, et al. JCPP Adv. 2024 Apr 15;4(2):e12233. doi: 10.1002/jcv2.12233. eCollection 2024 Jun. JCPP Adv. 2024. PMID: 38827986 Free PMC article.
OBJECTIVE: Early measurement of atypical disruptive behavior within autistic children is critical for later referrals to behavioral screenings, diagnoses, and services. Disruptive behavior in autistic toddlers is often measured using a categorical approach and ident …
OBJECTIVE: Early measurement of atypical disruptive behavior within autistic children is critical for later referrals to behavioral s …
Neurobiology of cognitive abilities in early childhood autism.
Denisova K. Denisova K. JCPP Adv. 2024 Jan 20;4(2):e12214. doi: 10.1002/jcv2.12214. eCollection 2024 Jun. JCPP Adv. 2024. PMID: 38827984 Free PMC article.
This perspective considers complexities in the relationship between impaired cognitive abilities and autism from a maturational, developmental perspective, and aims to serve as a helpful guide for the complex and growing investigation of cognitive abilities and Autism
This perspective considers complexities in the relationship between impaired cognitive abilities and autism from a maturational, deve …
The distribution of parent-reported attention-deficit/hyperactivity disorder and subclinical autistic traits in children with and without an ADHD diagnosis.
Chau T, Tiego J, Brown LE, Mellahn OJ, Johnson BP, Arnatkeviciute A, Fulcher BD, Matthews N, Bellgrove MA. Chau T, et al. JCPP Adv. 2024 Feb 24;4(2):e12223. doi: 10.1002/jcv2.12223. eCollection 2024 Jun. JCPP Adv. 2024. PMID: 38827983 Free PMC article.
BACKGROUND: Autistic traits are often reported to be elevated in children diagnosed with attention-deficit/hyperactivity disorder (ADHD). ...RESULTS: A 2-factor, 2-class factor mixture model with class varying factor variances and intercepts demonstrated the best fi …
BACKGROUND: Autistic traits are often reported to be elevated in children diagnosed with attention-deficit/hyperactivity disorder
Trajectories of adaptive functioning from early childhood to adolescence in autism: Identifying turning points and key correlates of chronogeneity.
Chen YJ, Duku E, Szatmari P, Salt M, Smith I, Richard A, Zwaigenbaum L, Vaillancourt T, Zaidman-Zait A, Bennett T, Elsabbagh M, Kerns C, Georgiades S. Chen YJ, et al. JCPP Adv. 2023 Dec 14;4(2):e12212. doi: 10.1002/jcv2.12212. eCollection 2024 Jun. JCPP Adv. 2023. PMID: 38827978 Free PMC article.
BACKGROUND: Previous research has demonstrated heterogeneous adaptive outcomes across the autism spectrum; however, the current literature remains limited in elucidating turning points and associated factors for longitudinal variability (chronogeneity). To address these em …
BACKGROUND: Previous research has demonstrated heterogeneous adaptive outcomes across the autism spectrum; however, the current liter …
Parents of children with autism spectrum disorder quality of life in Jordan: a comparative study.
Kasem A, Abuhammad S, Jamal N. Kasem A, et al. Future Sci OA. 2024 May 15;10(1):FSO909. doi: 10.2144/fsoa-2023-0096. eCollection 2024. Future Sci OA. 2024. PMID: 38827808 Free PMC article.
Aim: This study aimed to assess the quality of life (QoL) of parents of children with autism spectrum disorder (ASD) in Jordan and its associated factors. ...Data collection took four setting areas that include three centers for autism in three different muni …
Aim: This study aimed to assess the quality of life (QoL) of parents of children with autism spectrum disorder (ASD) in Jordan …
Association of mental disorders with sepsis: a bidirectional Mendelian randomization study.
Hu Y, Xiong Z, Huang P, He W, Zhong M, Zhang D, Tang G. Hu Y, et al. Front Public Health. 2024 May 17;12:1327315. doi: 10.3389/fpubh.2024.1327315. eCollection 2024. Front Public Health. 2024. PMID: 38827616 Free PMC article.
Nevertheless, the causal connection between a particular psychological disorder and sepsis remains unclear. METHODS: For investigating the causal relationships between mental disorders and sepsis, genetic variants correlated with mental disorders, including anorexia nervos …
Nevertheless, the causal connection between a particular psychological disorder and sepsis remains unclear. METHODS: For investigatin …
Causal effects of 731 immune cell phenotypes on autism spectrum disorder: a Mendelian randomization study.
Yu Y, Yang X, Hu G, Yin Y, Yu R. Yu Y, et al. Front Psychiatry. 2024 May 16;15:1397006. doi: 10.3389/fpsyt.2024.1397006. eCollection 2024. Front Psychiatry. 2024. PMID: 38827447 Free PMC article.
OBJECTIVE: The role of different immune cells in autism spectrum disorders (ASD) is still controversial. The purpose of this study was to evaluate the causal effects of different immune cell phenotypes on ASD via Mendelian randomization (MR). ...
OBJECTIVE: The role of different immune cells in autism spectrum disorders (ASD) is still controversial. The purpose of this study wa …
Defining cis-regulatory elements and transcription factors that control human cortical interneuron development.
Chapman G, Determan J, Jetter H, Kaushik K, Prakasam R, Kroll KL. Chapman G, et al. iScience. 2024 May 11;27(6):109967. doi: 10.1016/j.isci.2024.109967. eCollection 2024 Jun 21. iScience. 2024. PMID: 38827400 Free PMC article.
We used these data to define candidate transcription factors (TFs) that may bind these CREs to regulate interneuron progenitor specification. Among these were RFX3 and RFX4, risk genes for autism spectrum disorder (ASD) with uncharacterized roles in human neuronal d …
We used these data to define candidate transcription factors (TFs) that may bind these CREs to regulate interneuron progenitor specification …
Characterizing the clinical and sociodemographic profiles of hospitalized adolescents with autism spectrum disorder.
Avrahami M, Ben-Dor DH, Ratzon R, Weizman A, Perlman Danieli P. Avrahami M, et al. Glob Ment Health (Camb). 2024 May 13;11:e63. doi: 10.1017/gmh.2024.63. eCollection 2024. Glob Ment Health (Camb). 2024. PMID: 38827333 Free PMC article.
The prevalence of autism spectrum disorder (ASD) is increasing worldwide. Youngsters with ASD demonstrate higher rates of intellectual disabilities (IDs), comorbid psychopathology and psychiatric hospitalizations, compared to children in the general population. ...I …
The prevalence of autism spectrum disorder (ASD) is increasing worldwide. Youngsters with ASD demonstrate higher rates of inte …
Utilizing Large Language Models to Generate Synthetic Data to Increase the Performance of BERT-Based Neural Networks.
Woolsey CR, Bisht P, Rothman J, Leroy G. Woolsey CR, et al. AMIA Jt Summits Transl Sci Proc. 2024 May 31;2024:429-438. eCollection 2024. AMIA Jt Summits Transl Sci Proc. 2024. PMID: 38827067 Free PMC article.
We evaluated large language models (LLMs) for data creation. Using Autism Spectrum Disorders (ASD), we prompted GPT-3.5 and GPT-4 to generate 4,200 synthetic examples of behaviors to augment existing medical observations. Our goal is to label behaviors corresponding to …
We evaluated large language models (LLMs) for data creation. Using Autism Spectrum Disorders (ASD), we prompted GPT-3.5 and GPT-4 to …
Crowdsourcing with Enhanced Data Quality Assurance: An Efficient Approach to Mitigate Resource Scarcity Challenges in Training Large Language Models for Healthcare.
Barai P, Leroy G, Bisht P, Rothman JM, Lee S, Andrews J, Rice SA, Ahmed A. Barai P, et al. AMIA Jt Summits Transl Sci Proc. 2024 May 31;2024:75-84. eCollection 2024. AMIA Jt Summits Transl Sci Proc. 2024. PMID: 38827063 Free PMC article.
Our study evaluated the effectiveness of enhancing data quality through its impact on LLMs (Bio-BERT) for predicting autism-related symptoms. The results show that real-time quality control improves data quality by 19% compared to pre-quality control. ...
Our study evaluated the effectiveness of enhancing data quality through its impact on LLMs (Bio-BERT) for predicting autism-related s …
Amitriptyline-Induced Hyperprolactinemia in a Pediatric Patient.
Centner S, Cooper F, Gurnurkar S, Hasan S. Centner S, et al. Cureus. 2024 May 3;16(5):e59604. doi: 10.7759/cureus.59604. eCollection 2024 May. Cureus. 2024. PMID: 38826982 Free PMC article.
Hyperprolactinemia is an endocrinological disorder that might arise from various physiologic or pathologic conditions, as well as from pharmacologic sources. ...We present a case of a 10-year-old patient with a history of autism spectrum disorder (ASD), atten …
Hyperprolactinemia is an endocrinological disorder that might arise from various physiologic or pathologic conditions, as well as fro …
Navigating Community-Based Psychiatry Care of Pediatric Patients in Low-Resource Settings: A Case Report.
Regian N, Mittal A, Chammany M, Rai HP, Rommen M. Regian N, et al. Cureus. 2024 May 2;16(5):e59506. doi: 10.7759/cureus.59506. eCollection 2024 May. Cureus. 2024. PMID: 38826973 Free PMC article.
This case report examines the experience of a nine-year-old male with autism spectrum disorder (ASD) who was admitted to his rural community emergency department (ED) for the treatment of aggressive behaviors, agitation, and violence. Despite a high prevalence of su …
This case report examines the experience of a nine-year-old male with autism spectrum disorder (ASD) who was admitted to his r …
Recognition of autism spectrum disorder in children based on electroencephalogram network topology.
Li F, Zhang S, Jiang L, Duan K, Feng R, Zhang Y, Zhang G, Zhang Y, Li P, Yao D, Xie J, Xu W, Xu P. Li F, et al. Cogn Neurodyn. 2024 Jun;18(3):1033-1045. doi: 10.1007/s11571-023-09962-y. Epub 2023 Apr 12. Cogn Neurodyn. 2024. PMID: 38826670
Although our knowledge of autism spectrum disorder (ASD) has been deepened, the accurate diagnosis of ASD from normal individuals is still left behind. ...
Although our knowledge of autism spectrum disorder (ASD) has been deepened, the accurate diagnosis of ASD from normal individu …
EEG decoding for effects of visual joint attention training on ASD patients with interpretable and lightweight convolutional neural network.
Tan J, Zhan Y, Tang Y, Bao W, Tian Y. Tan J, et al. Cogn Neurodyn. 2024 Jun;18(3):947-960. doi: 10.1007/s11571-023-09947-x. Epub 2023 Mar 7. Cogn Neurodyn. 2024. PMID: 38826651 Free PMC article.
Visual joint attention, the ability to track gaze and recognize intent, plays a key role in the development of social and language skills in health humans, which is performed abnormally hard in autism spectrum disorder (ASD). The traditional convolutional neural net …
Visual joint attention, the ability to track gaze and recognize intent, plays a key role in the development of social and language skills in …
Quantitative Assessment of Morphological Changes in Lipid Droplets and Lipid-Mito Interactions with Aging in Brown Adipose.
Crabtree A, Neikirk K, Pinette J, Whiteside A, Shao B, McKenzie J, Vue Z, Vang L, Le H, Dermici M, Ahmad T, Owens TC, Oliver A, Zeleke F, Beasley HK, Lopez EG, Scudese E, Rodman T, Kabugi K, Koh A, Navarro S, Lam J, Kirk B, Mungai M, Sweetwyne M, Koh HJ, Zaganjor E, Damo SM, Gaddy JA, Kirabo A, Murray SA, Cooper A, Williams C, McReynolds MR, Marshall AG, Hinton A Jr. Crabtree A, et al. bioRxiv [Preprint]. 2024 May 21:2023.09.23.559135. doi: 10.1101/2023.09.23.559135. bioRxiv. 2024. PMID: 38826465 Free PMC article. Preprint.
Complimentary vertebrate Wac models exhibit phenotypes relevant to DeSanto-Shinawi Syndrome.
Lee KH, Stafford AM, Pacheco-Vergara M, Cichewicz K, Canales CP, Seban N, Corea M, Rahbarian D, Bonekamp KE, Gillie GR, Cruz DP, Gill AM, Hwang HE, Uhl KL, Jager TE, Shinawi M, Li X, Obenaus A, Crandall SR, Jeong J, Nord AS, Kim CH, Vogt D. Lee KH, et al. bioRxiv [Preprint]. 2024 May 26:2024.05.26.595966. doi: 10.1101/2024.05.26.595966. bioRxiv. 2024. PMID: 38826421 Free PMC article. Preprint.
Monogenic syndromes are associated with neurodevelopmental changes that result in cognitive impairments, neurobehavioral phenotypes including autism and attention deficit hyperactivity disorder (ADHD), and seizures. ...One such example is DeSanto-Shinawi Syndrome (D …
Monogenic syndromes are associated with neurodevelopmental changes that result in cognitive impairments, neurobehavioral phenotypes includin …
Cell-type-specific effects of autism-associated chromosome 15q11.2-13.1 duplications in human brain.
Dias C, Mo A, Cai C, Sun L, Cabral K, Brownstein CA, Rockowitz S, Walsh CA. Dias C, et al. bioRxiv [Preprint]. 2024 May 22:2024.05.22.595175. doi: 10.1101/2024.05.22.595175. bioRxiv. 2024. PMID: 38826276 Free PMC article. Preprint.
Recurrent copy number variation represents one of the most well-established genetic drivers in neurodevelopmental disorders, including autism spectrum disorder (ASD). Duplication of 15q11.2-13.1 (dup15q) is a well-described neurodevelopmental syndrome that increases …
Recurrent copy number variation represents one of the most well-established genetic drivers in neurodevelopmental disorders, including au
The interaction between social determinants of health, health behaviors, and child's intellectual developmental diagnosis.
Tchoua PP, Clarke E, Wasser H, Agrawal S, Scothorn R, Thompson K, Schenkelberg M, Willis EA. Tchoua PP, et al. medRxiv [Preprint]. 2024 May 25:2024.05.23.24307804. doi: 10.1101/2024.05.23.24307804. medRxiv. 2024. PMID: 38826242 Free PMC article. Preprint.
Therefore, we examined the influence of SDOH and children's diagnosis (typically developing [TD], Down syndrome [DS], autism) on caregiver's self-report of meeting evidence-based health practices. ...The DS group had the lowest SDOH score (mean = 8.41.0) compared to aut
Therefore, we examined the influence of SDOH and children's diagnosis (typically developing [TD], Down syndrome [DS], autism) on care …
A microglia-containing cerebral organoid model to study early life immune challenges.
Buonfiglioli A, Kübler R, Missall R, Jong R, Chan S, Haage V, Wendt S, Lin AJ, Mattei D, Graziani M, Latour B, Gigase F, Nygaard HB, De Jager PL, De Witte LD. Buonfiglioli A, et al. bioRxiv [Preprint]. 2024 May 29:2024.05.24.595814. doi: 10.1101/2024.05.24.595814. bioRxiv. 2024. PMID: 38826204 Free PMC article. Preprint.
Specifically, interferon-gamma (IFN-gamma) was found to alter the expression of genes linked to autism. This model provides a valuable tool to study how inflammatory perturbations and microglial presence affect neurodevelopmental processes....
Specifically, interferon-gamma (IFN-gamma) was found to alter the expression of genes linked to autism. This model provides a valuabl …
Exploiting ChatGPT for Diagnosing Autism-Associated Language Disorders and Identifying Distinct Features.
Hu C, Li W, Ruan M, Yu X, Paul LK, Wang S, Li X. Hu C, et al. Res Sq [Preprint]. 2024 May 21:rs.3.rs-4359726. doi: 10.21203/rs.3.rs-4359726/v1. Res Sq. 2024. PMID: 38826194 Free PMC article. Preprint.
Diagnosing language disorders associated with autism is a complex and nuanced challenge, often hindered by the subjective nature and variability of traditional assessment methods. ...Our approach not only promises greater diagnostic precision but also aligns with the goals …
Diagnosing language disorders associated with autism is a complex and nuanced challenge, often hindered by the subjective nature and …
Cost-utility analysis of Social Stories for children with autism spectrum disorder in mainstream primary schools: results from a randomised controlled trial.
Wang HI, Bell K, Blackwell J, Welch C, Mandefield L, Watson J, Standley E, McMillan D, Gilbody S, Wright B, Hewitt C, Parrott S. Wang HI, et al. BJPsych Open. 2024 Jun 3;10(4):e123. doi: 10.1192/bjo.2024.47. BJPsych Open. 2024. PMID: 38826027 Free article.
BACKGROUND: One in 57 children are diagnosed with autism in the UK, and the estimated cost for supporting these children in education is substantial. ...METHOD: Children with autism who were aged 4-11 years were recruited and randomised (N = 249). ...
BACKGROUND: One in 57 children are diagnosed with autism in the UK, and the estimated cost for supporting these children in education …
Shedding light on subiculum's role in human brain disorders.
Baset A, Huang F. Baset A, et al. Brain Res Bull. 2024 May 31;214:110993. doi: 10.1016/j.brainresbull.2024.110993. Online ahead of print. Brain Res Bull. 2024. PMID: 38825254 Free article. Review.
Moreover, the subiculum exhibits structural and functional changes in anxiety, schizophrenia, and Parkinson's disease, contributing to cognitive deficits. Bipolar disorder is linked to subiculum structural abnormalities, while autism spectrum disorder reveals …
Moreover, the subiculum exhibits structural and functional changes in anxiety, schizophrenia, and Parkinson's disease, contributing to cogni …