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Gastrointestinal manifestations and their relation to faecal calprotectin in children with autism.
Azouz HG, Zakaria NHE, Khalil AF, Naguib SM, Khalil M. Azouz HG, et al. Prz Gastroenterol. 2021;16(4):352-357. doi: 10.5114/pg.2021.111420. Epub 2021 Dec 2. Prz Gastroenterol. 2021. PMID: 34976244 Free PMC article.
INTRODUCTION: A common comorbidity in autism spectrum disorder (ASD) children is gastrointestinal problems, and a possible link between active gastrointestinal inflammation and autism has been suggested. ...MATERIAL AND METHODS: Calprotectin levels wer …
INTRODUCTION: A common comorbidity in autism spectrum disorder (ASD) children is gastrointestinal problems, and a possible lin …
Targeting S100A9 attenuates social dysfunction by modulating neuroinflammation and myelination in a mouse model of autism.
Gong H, Lu Y, Deng SL, Lv KY, Luo J, Luo Y, Du ZL, Wu LF, Liu TY, Wang XQ, Zhao JH, Wang L, Xia ML, Zhu DM, Wang LW, Fan XT. Gong H, et al. Pharmacol Res. 2025 Jan;211:107568. doi: 10.1016/j.phrs.2024.107568. Epub 2024 Dec 27. Pharmacol Res. 2025. PMID: 39733843 Free article.
Growing evidence supports a role for dysregulated neuroinflammation in autism. However, the underlying mechanisms of microglia-evoked neuroinflammation in the development of autistic phenotypes have not been elucidated. This study aimed to investigate the role and u …
Growing evidence supports a role for dysregulated neuroinflammation in autism. However, the underlying mechanisms of microglia-evoked …
Fecal calprotectin levels correlate with main domains of the autism diagnostic interview-revised (ADI-R) in a sample of individuals with autism spectrum disorders from Slovakia.
Babinská K, Tomova A, Celušáková H, Babková J, Repiská G, Kubranská A, Filčíková D, Siklenková L, Ostatníková D. Babinská K, et al. Physiol Res. 2017 Dec 30;66(Suppl 4):S517-S522. doi: 10.33549/physiolres.933801. Physiol Res. 2017. PMID: 29355379 Free article.
Autism spectrum disorders (ASD) are neurodevelopmental disorders characterized by impaired social interaction and communication, as well as repetitive behavior and restricted interests. ...In non-relatives significantly lower values of fecal calprotectin were observ …
Autism spectrum disorders (ASD) are neurodevelopmental disorders characterized by impaired social interaction and communication, as w …
Gut Microbiota and Autism Spectrum Disorder: A Neuroinflammatory Mediated Mechanism of Pathogenesis?
Zarimeidani F, Rahmati R, Mostafavi M, Darvishi M, Khodadadi S, Mohammadi M, Shamlou F, Bakhtiyari S, Alipourfard I. Zarimeidani F, et al. Inflammation. 2025 Apr;48(2):501-519. doi: 10.1007/s10753-024-02061-y. Epub 2024 Aug 2. Inflammation. 2025. PMID: 39093342 Free PMC article. Review.
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impairments in social communication and behavior, frequently accompanied by restricted and repetitive patterns of interests or activities. ...It deems the repair of microbiota lo …
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impairments in social communication an …
Gut microbiota in children and adolescents with autism, ADHD and anorexia nervosa, and its link to the levels of satiety hormones.
Soltysova M, Tomova A, Paulinyova M, Lakatosova S, Trebaticka J, Ostatnikova D. Soltysova M, et al. Neuroscience. 2025 Oct 15;585:394-407. doi: 10.1016/j.neuroscience.2025.08.020. Epub 2025 Aug 20. Neuroscience. 2025. PMID: 40846210
Neurodevelopmental disorders such as autism spectrum disorder (ASD), attention-deficit/hyperactivity disorder (ADHD), and anorexia nervosa (AN) significantly impact affected individuals and their families. ...Girls with AN displayed a decreased Firmicutes and …
Neurodevelopmental disorders such as autism spectrum disorder (ASD), attention-deficit/hyperactivity disorder (ADHD), a …
The search for gastrointestinal inflammation in autism: a systematic review and meta-analysis of non-invasive gastrointestinal markers.
Mathew NE, McCaffrey D, Walker AK, Mallitt KA, Masi A, Morris MJ, Ooi CY. Mathew NE, et al. Mol Autism. 2024 Jan 17;15(1):4. doi: 10.1186/s13229-023-00575-0. Mol Autism. 2024. PMID: 38233886 Free PMC article.
A total of 508 autistic children and adolescents and 397 non-autistic children and adolescents were included in the meta-analysis of calprotectin studies which found no significant group differences (ROM: 1.30 [0.91, 1.86]). ...Preliminary evidence suggests h …
A total of 508 autistic children and adolescents and 397 non-autistic children and adolescents were included in the meta-analy …
No evidence for a clear link between active intestinal inflammation and autism based on analyses of faecal calprotectin and rectal nitric oxide.
Fernell E, Fagerberg UL, Hellström PM. Fernell E, et al. Acta Paediatr. 2007 Jul;96(7):1076-9. doi: 10.1111/j.1651-2227.2007.00298.x. Epub 2007 Apr 27. Acta Paediatr. 2007. PMID: 17465982
METHODS: Twenty-four consecutive children with autism (3-13 years) of unknown aetiology were investigated with respect to faecal calprotectin and rectal nitric oxide (NO). ...CONCLUSION: By the use of two independent markers of inflammatory reactions in the gut, i.e …
METHODS: Twenty-four consecutive children with autism (3-13 years) of unknown aetiology were investigated with respect to faecal c …
Evaluation of Intestinal Function in Children With Autism and Gastrointestinal Symptoms.
Kushak RI, Buie TM, Murray KF, Newburg DS, Chen C, Nestoridi E, Winter HS. Kushak RI, et al. J Pediatr Gastroenterol Nutr. 2016 May;62(5):687-91. doi: 10.1097/MPG.0000000000001174. J Pediatr Gastroenterol Nutr. 2016. PMID: 26913756
RESULTS: Some children with autism had mild levels of mucosal inflammation on intestinal biopsy. Disaccharidase activity was not different in autistic and nonautistic individuals. Fecal calprotectin and lactoferrin were similar in both groups. Differences bet …
RESULTS: Some children with autism had mild levels of mucosal inflammation on intestinal biopsy. Disaccharidase activity was not diff …
Kefir-derived probiotic mixture for children with autism spectrum disorder: a double-blind randomized clinical trial.
de Queiroz SAL, Guimarães DO, Ferreira LA, Martinelli L, Werly RMM, Amorim RF, Holzbach LBSS, Badaró R, Santos AAB, Vasquez EC, Silva RS. de Queiroz SAL, et al. BMC Pediatr. 2026 Jan 17;26(1):186. doi: 10.1186/s12887-026-06515-0. BMC Pediatr. 2026. PMID: 41547752 Free PMC article.
This trial aimed to evaluate the effects of kefir-derived probiotics (K11 and K11-TMAX) on adaptive functioning, autism-related traits, and inflammatory/metabolic markers in children with Autism Spectrum Disorder (ASD). ...The primary outcome was the change i …
This trial aimed to evaluate the effects of kefir-derived probiotics (K11 and K11-TMAX) on adaptive functioning, autism-related trait …
Plasma levels of glial cell marker S100B in children with autism.
Tomova A, Keményová P, Filčíková D, Szapuová Ž, Kováč A, Babinská K, Ostatníková D. Tomova A, et al. Physiol Res. 2019 Dec 20;68(Suppl 3):S315-S323. doi: 10.33549/physiolres.934350. Physiol Res. 2019. PMID: 31928049 Free article.
Autism spectrum disorder (ASD) is a neurodevelopmental condition with increasing incidence. ...Correlation of plasma S100B levels with stool calprotectin concentrations was found, suggesting not only brain astrocytes, but also enteric glial cells may take par …
Autism spectrum disorder (ASD) is a neurodevelopmental condition with increasing incidence. ...Correlation of plasma S100B lev …
24 results