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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1942 1
1944 2
1945 99
1946 377
1947 410
1948 517
1949 494
1950 1044
1951 1311
1952 1250
1953 1229
1954 1166
1955 1179
1956 1111
1957 1126
1958 1164
1959 978
1960 907
1961 1188
1962 1382
1963 2226
1964 2854
1965 2534
1966 2434
1967 2755
1968 3076
1969 3376
1970 3434
1971 3639
1972 3586
1973 3723
1974 3707
1975 3753
1976 3791
1977 3918
1978 4226
1979 4219
1980 4168
1981 4591
1982 5036
1983 5566
1984 6239
1985 6445
1986 6603
1987 7123
1988 7481
1989 7875
1990 7971
1991 7935
1992 8518
1993 8785
1994 8875
1995 8613
1996 8883
1997 9273
1998 9588
1999 9934
2000 10087
2001 10501
2002 11123
2003 11596
2004 12273
2005 13690
2006 13986
2007 14770
2008 15774
2009 16586
2010 17716
2011 18959
2012 20317
2013 20986
2014 21654
2015 22143
2016 22579
2017 22877
2018 23568
2019 23299
2020 16501
2021 736
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Search Results

546,429 results
Results by year
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Page 1
Autoimmune Addison's disease - An update on pathogenesis.
Hellesen A, Bratland E, Husebye ES. Hellesen A, et al. Ann Endocrinol (Paris). 2018 Jun;79(3):157-163. doi: 10.1016/j.ando.2018.03.008. Epub 2018 Apr 7. Ann Endocrinol (Paris). 2018. PMID: 29631795 Review.
The immune-mediated attack on adrenocortical cells cripples their ability to synthesize vital steroid hormones and necessitates life-long hormone replacement therapy. The autoimmune disease etiology is multifactorial involving variants in immune genes and environmen …
The immune-mediated attack on adrenocortical cells cripples their ability to synthesize vital steroid hormones and necessitates life-long ho …
Sex Hormones in Acquired Immunity and Autoimmune Disease.
Moulton VR. Moulton VR. Front Immunol. 2018 Oct 4;9:2279. doi: 10.3389/fimmu.2018.02279. eCollection 2018. Front Immunol. 2018. PMID: 30337927 Free PMC article. Review.
Paradoxically, the stronger immune response comes at a steep price, which is the high incidence of autoimmune diseases in women. The reasons why women have stronger immunity and higher incidence of autoimmunity are not clear. ...This review focuses on the role of se …
Paradoxically, the stronger immune response comes at a steep price, which is the high incidence of autoimmune diseases in wome …
Stress as a trigger of autoimmune disease.
Stojanovich L, Marisavljevich D. Stojanovich L, et al. Autoimmun Rev. 2008 Jan;7(3):209-13. doi: 10.1016/j.autrev.2007.11.007. Epub 2007 Nov 29. Autoimmun Rev. 2008. PMID: 18190880 Review.
The etiology of autoimmune diseases is multifactorial: genetic, environmental, hormonal, and immunological factors are all considered important in their development. ...The treatment of autoimmune disease should thus include stress management and behav …
The etiology of autoimmune diseases is multifactorial: genetic, environmental, hormonal, and immunological factors are all con …
Human autoimmune diseases: a comprehensive update.
Wang L, Wang FS, Gershwin ME. Wang L, et al. J Intern Med. 2015 Oct;278(4):369-95. doi: 10.1111/joim.12395. Epub 2015 Jul 25. J Intern Med. 2015. PMID: 26212387 Free article. Review.
Such pioneering efforts led to a better understanding not only of autoimmunity, but also of lymphoid cell development, thymic education, apoptosis and deletion of autoreactive cells. Contemporary theories suggest that the development of an autoimmune disease require …
Such pioneering efforts led to a better understanding not only of autoimmunity, but also of lymphoid cell development, thymic education, apo …
Pathogen infection and autoimmune disease.
Christen U. Christen U. Clin Exp Immunol. 2019 Jan;195(1):10-14. doi: 10.1111/cei.13239. Clin Exp Immunol. 2019. PMID: 30569518 Free PMC article. No abstract available.
Gene Therapy for Autoimmune Disease.
Shu SA, Wang J, Tao MH, Leung PS. Shu SA, et al. Clin Rev Allergy Immunol. 2015 Oct;49(2):163-76. doi: 10.1007/s12016-014-8451-x. Clin Rev Allergy Immunol. 2015. PMID: 25277817 Review.
Advances in understanding the immunological and molecular basis of autoimmune diseases have made gene therapy a promising approach to treat the affected patients. ...Here, we summarize the recent progress in identifying genes responsible for autoimmune dis
Advances in understanding the immunological and molecular basis of autoimmune diseases have made gene therapy a promising appr …
Prediction and Prevention of Autoimmune Disease in the 21st Century: A Review and Preview.
Rose NR. Rose NR. Am J Epidemiol. 2016 Mar 1;183(5):403-6. doi: 10.1093/aje/kwv292. Epub 2016 Feb 17. Am J Epidemiol. 2016. PMID: 26888748 Review.
Collectively, autoimmune diseases affect some 20 million Americans, predominantly women. Many of these diseases are increasing in frequency in industrialized countries. Treatment of autoimmune diseases improved greatly during the second half of …
Collectively, autoimmune diseases affect some 20 million Americans, predominantly women. Many of these diseases are inc …
[Leptin and autoimmune disease].
Fujita Y. Fujita Y. Nihon Rinsho Meneki Gakkai Kaishi. 2017;40(3):155-159. doi: 10.2177/jsci.40.155. Nihon Rinsho Meneki Gakkai Kaishi. 2017. PMID: 28747601 Free article. Review. Japanese.
On the other hand, the leptin receptor is also expressed in hematopoietic cells and its action on the immune system has become known, and the significance of leptin in autoimmune diseases has gradually become clear. It has been shown that leptin acts as an exacerbat …
On the other hand, the leptin receptor is also expressed in hematopoietic cells and its action on the immune system has become known, and th …
Antibody therapeutics and immunoregulation in cancer and autoimmune disease.
Yasunaga M. Yasunaga M. Semin Cancer Biol. 2020 Aug;64:1-12. doi: 10.1016/j.semcancer.2019.06.001. Epub 2019 Jun 7. Semin Cancer Biol. 2020. PMID: 31181267 Free article. Review.
Cancer and autoimmune disease are closely related, and many therapeutic antibodies are widely used in clinics for the treatment of both diseases. ...In addition, next-generation antibody therapeutics such as antibody-drug conjugates and bispecific antibodies, …
Cancer and autoimmune disease are closely related, and many therapeutic antibodies are widely used in clinics for the treatmen …
Type I Interferons in Autoimmune Disease.
Crow MK, Olferiev M, Kirou KA. Crow MK, et al. Annu Rev Pathol. 2019 Jan 24;14:369-393. doi: 10.1146/annurev-pathol-020117-043952. Epub 2018 Oct 17. Annu Rev Pathol. 2019. PMID: 30332560 Review.
Type I interferons, which make up the first cytokine family to be described and are the essential mediators of antivirus host defense, have emerged as central elements in the immunopathology of systemic autoimmune diseases, with systemic lupus erythematosus as the p …
Type I interferons, which make up the first cytokine family to be described and are the essential mediators of antivirus host defense, have …
546,429 results
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