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1967 1696
1968 2106
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1972 2312
1973 2343
1974 2262
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1983 1950
1984 2274
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1989 2652
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2000 4525
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2005 7137
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2012 14319
2013 15474
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Regulation of cerebral blood flow in humans: physiology and clinical implications of autoregulation.
Claassen JAHR, Thijssen DHJ, Panerai RB, Faraci FM. Claassen JAHR, et al. Physiol Rev. 2021 Oct 1;101(4):1487-1559. doi: 10.1152/physrev.00022.2020. Epub 2021 Mar 26. Physiol Rev. 2021. PMID: 33769101 Free PMC article. Review.
This review focuses primarily on autoregulation and its clinical implications. To place autoregulation in a more precise context, and to better understand integrated approaches in the cerebral circulation, we also briefly address reactivity to CO(2) and NVC. ...We r …
This review focuses primarily on autoregulation and its clinical implications. To place autoregulation in a more precise conte …
Beyond intracranial pressure: monitoring cerebral perfusion and autoregulation in severe traumatic brain injury.
Dietvorst S, Depreitere B, Meyfroidt G. Dietvorst S, et al. Curr Opin Crit Care. 2023 Apr 1;29(2):85-88. doi: 10.1097/MCC.0000000000001026. Epub 2023 Feb 9. Curr Opin Crit Care. 2023. PMID: 36762674 Review.
RECENT FINDINGS: Cerebral autoregulation is often impaired in TBI patients, and monitoring cerebral autoregulation might be useful to develop personalized therapy rather than treatment of one size fits all thresholds and guidelines based on unidimensional static rel …
RECENT FINDINGS: Cerebral autoregulation is often impaired in TBI patients, and monitoring cerebral autoregulation might be us …
Neonatal cerebrovascular autoregulation.
Rhee CJ, da Costa CS, Austin T, Brady KM, Czosnyka M, Lee JK. Rhee CJ, et al. Pediatr Res. 2018 Nov;84(5):602-610. doi: 10.1038/s41390-018-0141-6. Epub 2018 Sep 8. Pediatr Res. 2018. PMID: 30196311 Free PMC article. Review.
Cerebral vasoreactivity refers to the vasoconstriction and vasodilation that occur during fluctuations in arterial blood pressure (ABP) to maintain autoregulation. These are vital protective mechanisms of the brain. Impairments in pressure autoregulation increase th …
Cerebral vasoreactivity refers to the vasoconstriction and vasodilation that occur during fluctuations in arterial blood pressure (ABP) to m …
Static autoregulation in humans.
Wang Y, Payne SJ. Wang Y, et al. J Cereb Blood Flow Metab. 2024 Nov;44(11):1191-1207. doi: 10.1177/0271678X231210430. Epub 2023 Nov 7. J Cereb Blood Flow Metab. 2024. PMID: 37933742 Free PMC article. Review.
The significant difference in CBF directional sensitivity suggests that cerebral autoregulation appears to be more effective in buffering increases in ABP than decreases in ABP. ...Age and sex were found to have no effect on autoregulation strength. This data-driven …
The significant difference in CBF directional sensitivity suggests that cerebral autoregulation appears to be more effective in buffe …
Why and how to assess cerebral autoregulation?
Moerman A, De Hert S. Moerman A, et al. Best Pract Res Clin Anaesthesiol. 2019 Jun;33(2):211-220. doi: 10.1016/j.bpa.2019.05.007. Epub 2019 Jul 22. Best Pract Res Clin Anaesthesiol. 2019. PMID: 31582100 Review.
It is now acknowledged that cerebral autoregulation is much more complicated than we previously thought it was, with the shape of the autoregulation curve and limits of autoregulation that may vary enormously and unpredictably, both within and between patient …
It is now acknowledged that cerebral autoregulation is much more complicated than we previously thought it was, with the shape of the …
Monitoring of cerebral blood flow autoregulation: physiologic basis, measurement, and clinical implications.
Vu EL, Brown CH 4th, Brady KM, Hogue CW. Vu EL, et al. Br J Anaesth. 2024 Jun;132(6):1260-1273. doi: 10.1016/j.bja.2024.01.043. Epub 2024 Mar 12. Br J Anaesth. 2024. PMID: 38471987 Review.
Clinical methods for monitoring CBF autoregulation were first developed for neurocritically ill patients and have been extended to surgical patients. ...In contrast to the traditional teaching that 50 mm Hg is the autoregulation threshold, these investigations have …
Clinical methods for monitoring CBF autoregulation were first developed for neurocritically ill patients and have been extended to su …
Coronary autoregulation.
Feigl EO. Feigl EO. J Hypertens Suppl. 1989 Sep;7(4):S55-8; discussion S59. J Hypertens Suppl. 1989. PMID: 2681597 Review.
Local metabolic vascular control appears to be the dominant factor in coronary autoregulation. If myocardial metabolism is enhanced, coronary autoregulation occurs at a higher level of flow. The balance between myocardial oxygen supply and demand is critical for cor …
Local metabolic vascular control appears to be the dominant factor in coronary autoregulation. If myocardial metabolism is enhanced, …
Cerebral Autoregulation-guided Management of Adult and Pediatric Traumatic Brain Injury.
Lele AV, Vavilala MS. Lele AV, et al. J Neurosurg Anesthesiol. 2023 Oct 1;35(4):354-360. doi: 10.1097/ANA.0000000000000933. Epub 2023 Jul 31. J Neurosurg Anesthesiol. 2023. PMID: 37523326 Review.
Cerebral autoregulation (CA) plays a vital role in maintaining cerebral blood flow in response to changes in systemic blood pressure. ...
Cerebral autoregulation (CA) plays a vital role in maintaining cerebral blood flow in response to changes in systemic blood pressure. …
Cerebral autoregulation.
Paulson OB, Strandgaard S, Edvinsson L. Paulson OB, et al. Cerebrovasc Brain Metab Rev. 1990 Summer;2(2):161-92. Cerebrovasc Brain Metab Rev. 1990. PMID: 2201348 Review.
Disease states of the brain may impair or abolish CBF autoregulation. Thus, autoregulation is lost in severe head injury or acute ischemic stroke, leaving surviving brain tissue unprotected against the potentially harmful effect of blood pressure changes. Likewise, …
Disease states of the brain may impair or abolish CBF autoregulation. Thus, autoregulation is lost in severe head injury or ac …
Quantification of dynamic cerebral autoregulation: welcome to the jungle!
Brassard P, Roy MA, Burma JS, Labrecque L, Smirl JD. Brassard P, et al. Clin Auton Res. 2023 Dec;33(6):791-810. doi: 10.1007/s10286-023-00986-2. Epub 2023 Sep 27. Clin Auton Res. 2023. PMID: 37758907 Review.
METHODS: In this narrative review, we go beyond the classical view of cerebral autoregulation to discuss dynamic cerebral autoregulation, focusing on recent advances pitfalls and future directions. RESULTS: Following some historical background, this narrative review …
METHODS: In this narrative review, we go beyond the classical view of cerebral autoregulation to discuss dynamic cerebral autoregu …
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