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Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Avanafil for the Treatment of men With Erectile Dysfunction: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
Li J, Peng L, Cao D, He L, Li Y, Wei Q. Li J, et al. Am J Mens Health. 2019 Sep-Oct;13(5):1557988319880764. doi: 10.1177/1557988319880764. Am J Mens Health. 2019. PMID: 31672076 Free PMC article.
Previous studies have reported the clinical efficacy of avanafil for erectile dysfunction (ED), but these findings are controversial. This study aims to investigate the safety and efficacy of avanafil for ED. ...The present evidence suggests that avanafil (es …
Previous studies have reported the clinical efficacy of avanafil for erectile dysfunction (ED), but these findings are controversial. …
Avanafil for male erectile dysfunction: a systematic review and meta-analysis.
Cui YS, Li N, Zong HT, Yan HL, Zhang Y. Cui YS, et al. Asian J Androl. 2014 May-Jun;16(3):472-7. doi: 10.4103/1008-682X.123670. Asian J Androl. 2014. PMID: 24589460 Free PMC article.
Specific AEs with avanafil included headache and flushing, which were significantly less likely to occur with placebo. This meta-analysis indicates that avanafil 100 or 200 mg is an effective and well-tolerated treatment for ED. Compared with avanafil 100 mg, …
Specific AEs with avanafil included headache and flushing, which were significantly less likely to occur with placebo. This meta-anal …
The effectiveness and safety of avanafil for erectile dysfunction: a systematic review and meta-analysis.
Wang H, Yuan J, Hu X, Tao K, Liu J, Hu D. Wang H, et al. Curr Med Res Opin. 2014 Aug;30(8):1565-71. doi: 10.1185/03007995.2014.909391. Epub 2014 Apr 14. Curr Med Res Opin. 2014. PMID: 24701971
OBJECTIVE: To compare the efficacy and safety between different dosages of avanafil for the treatment of erectile dysfunction (ED). METHODS: PubMed, Cochrane Library, and Embase were searched to identify randomized controlled trials which compared avanafil with plac …
OBJECTIVE: To compare the efficacy and safety between different dosages of avanafil for the treatment of erectile dysfunction (ED). M …
The safety and efficacy of Avanafil, a new 2(nd) generation PDE5i: comprehensive review and meta-analysis.
Corona G, Rastrelli G, Burri A, Jannini EA, Maggi M. Corona G, et al. Expert Opin Drug Saf. 2016;15(2):237-47. doi: 10.1517/14740338.2016.1130126. Epub 2016 Jan 20. Expert Opin Drug Saf. 2016. PMID: 26646748 Review.
So far, 5 different RCTs on avanafil have been published, including 1379 and 605 patients in active and placebo groups, respectively. Avanafil was up to 3-fold superior to placebo in determining successful sexual intercourse. ...
So far, 5 different RCTs on avanafil have been published, including 1379 and 605 patients in active and placebo groups, respectively. …
Efficacy and safety of avanafil as compared with sildenafil in the treatment of erectile dysfunction: A randomized, double blind, multicenter clinical trial.
Kumar M, Pathade AD, Gupta SV, Goyal S, Rath D, Thakre M, Sanmukhani J, Mittal R. Kumar M, et al. Int J Urol. 2022 Apr;29(4):351-359. doi: 10.1111/iju.14785. Epub 2022 Jan 26. Int J Urol. 2022. PMID: 35080051 Free PMC article. Clinical Trial.
OBJECTIVE: To compare the efficacy and safety of avanafil as compared with sildenafil in the management of patients with erectile dysfunction. ...RESULTS: A total of 220 patients were randomized to receive either avanafil tablets 100 mg or sildenafil tablets 50 mg i …
OBJECTIVE: To compare the efficacy and safety of avanafil as compared with sildenafil in the management of patients with erectile dys …
Evaluation of daily avanafil efficacy in improving the endothelial function in Egyptian males with erectile dysfunction.
Elkamshoushi AM, Badae NM, Kabary MG, Omar SI. Elkamshoushi AM, et al. Andrologia. 2021 Feb;53(1):e13833. doi: 10.1111/and.13833. Epub 2020 Oct 28. Andrologia. 2021. PMID: 33112433 Clinical Trial.
This study was conducted to assess the effect of daily avanafil on the endothelial markers' serum level and erectile function in patients with erectile dysfunction. ...These results permitted us to suggest that daily avanafil can improve the impaired endothelial fun …
This study was conducted to assess the effect of daily avanafil on the endothelial markers' serum level and erectile function in pati …
Avanafil for the treatment of erectile dysfunction: a multicenter, randomized, double-blind study in men with diabetes mellitus.
Goldstein I, Jones LA, Belkoff LH, Karlin GS, Bowden CH, Peterson CA, Trask BA, Day WW. Goldstein I, et al. Mayo Clin Proc. 2012 Sep;87(9):843-52. doi: 10.1016/j.mayocp.2012.06.016. Epub 2012 Aug 1. Mayo Clin Proc. 2012. PMID: 22857780 Free PMC article. Clinical Trial.
OBJECTIVE: To prospectively assess the safety and effectiveness of the investigational phosphodiesterase 5 inhibitor avanafil to treat erectile dysfunction in men with diabetes mellitus. PATIENTS AND METHODS: This 12-week, multicenter, double-blind, placebo-controlled stud …
OBJECTIVE: To prospectively assess the safety and effectiveness of the investigational phosphodiesterase 5 inhibitor avanafil to trea …
A Bioequivalence Study of Avanafil in Healthy Chinese Male Subjects Under Fasting and Fed Conditions: Results of a Randomized, Open-Label, Single-Dose, 2-Sequence, 2-Period Crossover Study.
Ren X, Yu H, Qi X, Chen Q, Yang J, Fang Y, Lei Y, Zhang D, Zuo Q, Liu D. Ren X, et al. Clin Pharmacol Drug Dev. 2021 Dec;10(12):1495-1502. doi: 10.1002/cpdd.998. Epub 2021 Jul 19. Clin Pharmacol Drug Dev. 2021. PMID: 34288578 Free PMC article. Clinical Trial.
This bioequivalence study was conducted to determine the pharmacokinetics and safety profiles of an originator and a generic avanafil formulation in Chinese male subjects under fed and fasting conditions. Each eligible subject was initially randomly given avanafil ( …
This bioequivalence study was conducted to determine the pharmacokinetics and safety profiles of an originator and a generic avanafil …
Efficacy of Avanafil 15 Minutes after Dosing in Men with Erectile Dysfunction: A Randomized, Double-Blind, Placebo Controlled Study.
Hellstrom WJ, Kaminetsky J, Belkoff LH, Goldstein I, Tursi JP, Uy J, Peterson CA, Bowden CH, Day WW. Hellstrom WJ, et al. J Urol. 2015 Aug;194(2):485-92. doi: 10.1016/j.juro.2014.12.101. Epub 2015 Jan 12. J Urol. 2015. PMID: 25591992 Clinical Trial.
PURPOSE: We examined the therapeutic effects of avanafil 15 minutes after dosing in men with mild to severe erectile dysfunction. MATERIALS AND METHODS: This randomized, double-blind, placebo controlled, 12-week study (4-week run-in and 8-week treatment) randomized 145 men …
PURPOSE: We examined the therapeutic effects of avanafil 15 minutes after dosing in men with mild to severe erectile dysfunction. MAT …
Tolerability and pharmacokinetics of avanafil, a phosphodiesterase type 5 inhibitor: a single- and multiple-dose, double-blind, randomized, placebo-controlled, dose-escalation study in healthy Korean male volunteers.
Jung J, Choi S, Cho SH, Ghim JL, Hwang A, Kim U, Kim BS, Koguchi A, Miyoshi S, Okabe H, Bae KS, Lim HS. Jung J, et al. Clin Ther. 2010 Jun;32(6):1178-87. doi: 10.1016/j.clinthera.2010.06.011. Clin Ther. 2010. PMID: 20637970 Clinical Trial.
BACKGROUND: Avanafil is a selective phosphodiesterase type 5 inhibitor being developed for the treatment of erectile dysfunction. OBJECTIVE: This study was conducted to meet Korean regulatory requirements for the marketing of avanafil. To this end, tolerability and …
BACKGROUND: Avanafil is a selective phosphodiesterase type 5 inhibitor being developed for the treatment of erectile dysfunction. OBJ …
25 results